Abstracts tagged "Nephritis"

Abstract Number: 1144 • ACR Convergence 2025
A quantitative study of renal medulla echogenicity in 250 Vietnames gout patients shows correlation with poor renal function
Thomas Bardin¹, Quang Nguyen², anouk Walter-Petrich³, Khoi Minh Tran², Duong Ba Pham², Quang Huy Nguyen⁴, Chuc Van Tran², Day Phuoc Huynh², Minh Do⁵, Emmanuel Letavernier⁶, richette pascal⁷, Matthieu Resche-Rigon³ and Jean-Michel Correas⁸, ¹Lariboisiere Hospital, Department of Rheumatology, Paris, France, ²Vien Gut Medical centre, Ho Chi Minh City, Vietnam, ³UMR U¹³⁴² ECSTRA team INERM, Université Paris Cité, Paris, France, ⁴Vien Gut Medicfal Centre, Ho Chi Minh City, ⁵University of Medicine and Pharmacy at Ho Chi Min City, Ho Chi Minh City, Vietnam, ⁶Sorbonne Université and INSERM, UMR S ¹¹⁵⁵, Hôpital Tenon, Paris, France, ⁷Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, ⁸Department of Radiology, NeckerUniversity Hospital, Paris, France
Background/Purpose: We previously described the frequent occurrence of an hyperechogenic pattern of the renal medulla following crystal deposition in untreated Vietnamese patients with severe tophaceous…
Abstract Number: 0922 • ACR Convergence 2025
Phenotypic and Transcriptomic Divergence in C3 Glomerular Mouse Models: Insights into Immune and Sex Correlates
Juan Liang¹ and kaiyuan zi², ¹Gempharmatech, Nanjing, Jiangsu, China, ²Gempharmatech, Nanjing, Jiangsu, Jiangsu, China
Background/Purpose: Complement component C3 plays a central role in the alternative pathway (AP) and is implicated in the pathogenesis of C3 glomerulopathy (C3G), a rare…
Abstract Number: 0646 • ACR Convergence 2025
A-319, a CD3×CD19 T Cell Engager, for the Treatment of Refractory Systemic Lupus Erythematosus: Preliminary Evidence of Autoimmune Reset
Chunli Mei¹, Xin Guan¹, Rong Du¹, Bin Wu², You Song¹, Xiaoqi Chen³, Mengjiao Li¹, Xiaojing Liu¹, Xi Cheng¹, Weiwei Wang¹, Cheng Wang¹, Huiling Mei¹, Xiaoru Duan¹, Lijuan Jiang¹, Wenlin Qiu¹, Likai Yu¹, Yuhong Liu¹, Di Wu¹, Guiqi Quan¹, Blal Chakhabi¹, Xing Zhao⁴, Xuanfan Zhong⁴, Shengjie Xue⁴, Wuzhong Shen⁴, Ying Tan⁴, Guojian Yu⁴, Guiyun Tu⁴, Hanyang Chen⁴, Amy Sun⁴, Jing Liang⁴, Sharon Song⁴, Jason Xu⁴, Xiaoqiang Yan⁴, Anbing Huang¹ and Qiubai Li⁵, ¹Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, WUHAN, China (People's Republic), ²First People’s Hospital of Jingzhou, Jingzhou, China (People's Republic), ³Zhongnan Hospital, Wuhan University, Wuhan, China (People's Republic), ⁴ITabMed Co., Ltd., Shanghai, China (People's Republic), ⁵Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (People's Republic)
Background/Purpose: Immune reset of autoimmune disease has been proposed to be a potential benefit of T cell engagers (TCEs) and CD19 CAR T therapy. A-319,…
Abstract Number: 0639 • ACR Convergence 2025
Kidney Transplantation In Lupus Nephritis. Multicenter Study Of 103 Patients
Vanesa Calvo-Río¹, Lara Sánchez Bilbao¹, Carmen Secada-Gómez¹, Paúl Hernández Velasco², Celia González-García³, Enrique Morales⁴, María Galindo-Izquierdo⁵, Sebastián Sandoval-Moreno⁶, Josefina Cortés-Hernández⁷, César Antonio Egües Dubuc⁸, Niccolo Viveros-Pérez⁹, María Caeiro¹⁰, Adrián Mayo-Juanatey¹¹, Miriam Retuerto Guerrero¹², María Camila Osorio-Sanjuan¹³, Luis Sala¹⁴ and Ricardo Blanco¹, ¹Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, ²Nephrology, Hospital Universitario ¹² de Octubre, Madrid. Spain, Madrid, Madrid, Spain, ³Rheumatology, Hospital Universitario ¹² de Octubre, Madrid, Madrid, Spain, ⁴Nephrology, Hospital Universitario ¹² de Octubre, Madrid, Madrid, Spain, ⁵Department of Rheumatology, Hospital Universitario ¹² de Octubre, Madrid, Spain, Madrid, Madrid, Spain, ⁶Hospital Universitario Vall D'Hebron, Barcelona, Spain, ⁷Hospital Universitari Vall d’Hebron-Universitat Autónoma de Barcelona, Barcelona, Spain, ⁸Donostia University Hospital, San Sebastián, Pais Vasco, Spain, ⁹Hospital Universitario Germans Trias i Pujol, Badalona, Spain, ¹⁰Centro Hospitalario Universitario de Pontevedra, Pontevedra, Spain, ¹¹Hospital Universitario Doctor Peset, Valencia, Comunidad Valenciana, Spain, ¹²Complejo Asistencial Universitario de León, Leon, Castilla y Leon, Spain, ¹³Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain, ¹⁴Hospital Universitario de Torrejón, Madrid, Spain
Background/Purpose: Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE) affecting to 40-60% of SLE. End-stage renal disease (ESRD) occurs in up…
Abstract Number: 0636 • ACR Convergence 2025
AA Novel Kidney-Specific Biomarker Panel Accurately Differentiates Lupus Nephritis from Diabetic Kidney Disease through Distinct Molecular Pathways Novel Kidney-Specific Biomarker Panel Accurately Differentiates Lupus Nephritis from Diabetic Kidney Disease through Distinct Molecular Pathways
Sepehr Taghavi¹, Ines Silva², Jacob Vasquez³, Vasileios Kyttaris⁴, Tyler O'Malley⁵ and Mike Nerenberg⁶, ¹Exagen Inc, Escondido, CA, ²Exagen, Carlsbad, CA, ³Exagen, Inc., Vista, CA, ⁴Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, ⁵Exagen, Vista, CA, ⁶Exagen, DEL MAR, CA
Background/Purpose: Lupus nephritis (LN) and diabetic kidney disease (DKD) are leading causes of chronic kidney disease (CKD) that differ by age, sex, and underlying mechanisms.…
Abstract Number: 0142 • ACR Convergence 2025
Risk Factors for Antiphospholipid Syndrome-associated Nephropathy: A Retrospective Cohort Analysis
Xiaohan Wei¹, Zhixia Yang², Haoyu Pan², Yuying Fan², Jinyi Qian², Shuyi Yu² and Hui Shi³, ¹Shanghai JiaoTong University, Shanghai, China (People's Republic), ²Department of Rheumatology and Immunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Shanghai, Shanghai, China (People's Republic), ³Shanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China (People's Republic)
Background/Purpose: To identify independent clinical and laboratory risk factors associated with antiphospholipid syndrome-associated nephropathy (APSN) and highlight the clinical importance of early screening in high-risk…
Abstract Number: 0136 • ACR Convergence 2025
Beyond Thrombosis: Histological Spectrum, Predictors and Outcomes of Renal Involvement in Primary Antiphospholipid Syndrome: A Single-Centre Cohort Study
RITESH KUMAR MISHRA¹, SUBIN PHILIP², RIZWANA NAUSHAD², AISHWARYA GOPAL³, Chengappa Kavadichanda², CHRISTINA MARIASELVAM², RAJESH N G², Molly mary Thabah³ and VIR SINGH NEGI², ¹JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, Bhubaneswar, India, ²JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, Puducherry, India, ³JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, India
Background/Purpose: Renal involvement in primary APS is underrecognized and histologically diverse, encompassing both vascular and glomerular pathology. We aimed to describe the histopathology, outcomes of…
Abstract Number: 2520 • ACR Convergence 2025
Evolution in Risk Stratification for Renal Outcomes in ANCA-Associated Vasculitides Using Established Scores and Histopathological Criteria in a Large European Cohort
Stefan Krämer¹, Kristian Vogt², Martin Busch³, Tobias Schmitt⁴, Raoul Bergner⁵, Sebastian Mosberger⁵, Thomas Neumann⁶, Teresa Schreibing¹, Fabian Schumbrink¹ and Thomas Rauen², ¹Department of Internal Medicine II, RWTH University Hospital Aachen, Aachen, Germany, ²Department of Internal Medicine II, RWTH University Hospital AachenMedicine II, Aachen, Germany, ³Department of Internal Medicine III, University Hospital, Friedrich-Schiller University, Jena, Jena, Germany, ⁴University Hospital Jena, Friedrich-Schiller University, Department of Internal Medicine III, Jena, Germany, ⁵Department of Internal Medicine A, Nephrology and Rheumatology, Municipal Hospital Ludwigshafen, Ludwigshafen, Germany, ⁶Department of Rheumatology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
Background/Purpose: Glomerulonephritis is a common and threatening manifestation in ANCA-associated vasculitis (AAV). To assess the risk of end-stage kidney disease (ESKD), various scores have been…
Abstract Number: 2446 • ACR Convergence 2025
Use of Voclosporin in Pediatric Patients: A Summary of Available Data from Post-marketing Reports
Eugenia Chock¹, Ankana Daga², Tasim Begum³, Kathryn Dao³ and Michelle Dardeno³, ¹Yale School of Medicine, New Haven, CT, ²Boston Children's Hospital, Boston, MA, ³Aurinia Pharmaceuticals Inc., Rockville, MD
Background/Purpose: Lupus nephritis (LN) is common in pediatric patients with systemic lupus erythematosus (SLE), with more than 50% developing renal manifestations, typically within the first…
Abstract Number: 2427 • ACR Convergence 2025
Kidney-Specific Four-Protein Index Outperforms Conventional Measures for Detecting Early Kidney Damage in Lupus Nephritis and Diabetic Kidney Disease
Sepehr Taghavi¹, Ines Silva², Jacob Vasquez³, Vasileios Kyttaris⁴, Tyler O'Malley⁵ and Mike Nerenberg⁶, ¹Exagen Inc, Escondido, CA, ²Exagen, Carlsbad, CA, ³Exagen, Inc., Vista, CA, ⁴Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, ⁵Exagen, Vista, CA, ⁶Exagen, DEL MAR, CA
Background/Purpose: Early detection of renal involvement in diabetic kidney disease (DKD) and lupus nephritis (LN) is critical but remains challenging. Conventional renal biomarkers (serum creatinine,…
Abstract Number: 1841 • ACR Convergence 2025
Differential metabolomic signatures along lupus nephritis spectrum
Mariana Jiménez Tirado¹, karina santana², Jiram Torres Ruiz³, Jennifer Tiaré Balderas Miranda⁴, Diana Gómez-Martín⁵, José Carlos Páez Franco⁶, Nancy R Mejía Domínguez⁷, Hilda Sánchez Vidal⁶ and Imelda Cecilia Zarzoza Mendoza⁸, ¹Instituto Nacional de Nutrición Salvador Zubirán, Mexico City, Distrito Federal, Mexico, ²INCMNSZ, Ciudad de México, Federal District, Mexico, ³INCMNSZ, Mexico, Federal District, Mexico, ⁴Universidad Nacional Autónoma de México, Coyoacán, Federal District, Mexico, ⁵INCMNSZ, Mexico city, Federal District, Mexico, ⁶Red de Apoyo a la Investigación, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Distrito Federal, Mexico, ⁷Universidad Nacional Autónoma de México, Mexico City, Distrito Federal, Mexico, ⁸Red de Apoyo a la Investigación, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán and Universidad Nacional Autónoma de México, Mexico City, Distrito Federal, Mexico
Background/Purpose: Lupus nephritis (LN) is a common feature in systemic lupus erythematosus (SLE) affecting up to 50% of the individuals with this disease. The gold…
Abstract Number: 1839 • ACR Convergence 2025
Transcriptional Profiling of Whole Blood and Kidney Biopsy Samples from Lupus Nephritis and IgA Nephropathy Patients Suggests Different Disease Pathways
Christopher Sisk¹, Loqmane Seridi², Alan Perlman³, Matthew Loza², Sheng Gao², Thomas Parker⁴, Daniel Levine⁴, Thangamani Muthukumar⁵, Yonatan Bardash⁶, Benjamin Horowitz⁷, Surya Seshan⁵ and James Chevalier³, ¹Johnson & Johnson, San Diego, CA, USA, San Diego, CA, CA, ²Johnson & Johnson, Spring House, PA, ³The Rogosin Institute, New York, NY, ⁴The Rogosin Institute, Weill Cornell Medical College, New York, NY, ⁵Weill Cornell Medical College, New York, NY, ⁶Hackensack Meridian Health, Hackensack, NJ, ⁷Columbia University Medical Center, New York, NY
Background/Purpose: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), associated with significant morbidity and mortality. IgA nephropathy (IgAN) is the most…
Abstract Number: 1759 • ACR Convergence 2025
Role of a pathogenic bacterial factor produced by a human gut pathobiont in inducing platelet activation and thrombo-inflammation.
Abhimanyu Amarnani¹, Cristobal F. Rivera², Susan RS Gottesman³, Zakia Azad¹, Mingyang Yi⁴, Joshua Prasad⁴, Cynthia Loomis⁴, Andy Lee⁴, Nimat Ullah⁴, Bhama Ramkhelawon⁵ and Gregg J. Silverman¹, ¹New York University Grossman School of Medicine, New York, NY, ²New York University Grossman Department of Surgery, New York, ³SUNY Downstate Health Sciences University, New York, ⁴New York University Grossman School of Medicine, New York, ⁵New York University Department of Surgery, New York
Background/Purpose: SLE is an autoimmune disease that causes progressive multi-organ damage, leading to renal injury, or lupus nephritis (LN), in half of patients. Despite treatment,…
Abstract Number: 1544 • ACR Convergence 2025
Voclosporin in Lupus Nephritis: Meta-Analysis of 6-Month and 1-Year Efficacy with 1-Year Safety Outcomes
Sri Laxmi Priya Sunkara¹, Ravi Medarametla², Megha Kotha³ and Wael Jarjour⁴, ¹White river medical center, batesville, AR, ²Mamata Medical College, Guntur, Andhra Pradesh, India, ³Ohio State University, Columbus, OH, ⁴The Ohio State University, Columbus, OH
Background/Purpose: Lupus nephritis (LN), is the most sever organ manifestation of systemic lupus erythematosus (SLE) and it contributes significantly to morbidity and mortality. . Standard…
Abstract Number: 1488 • ACR Convergence 2025
Limited Concordance Between anti-dsDNA Assays and Association with Lupus Nephritis
Jessica Dai¹, Peter Izmirly², Jill Buyon³ and H Michael Belmont⁴, ¹New York University Grossman School of Medicine, Tenafly, NJ, ²New York University Grossman School of Medicine, New York, NY, ³NYU Grossman School of Medicine, New York, NY, ⁴NYU School of Medicine, New York, NY
Background/Purpose: Anti-dsDNA antibodies are a key diagnostic marker of systemic lupus erythematosus (SLE), often associated with active disease. Its presence is detected using various commercial…

1
2
3
…
7
Next Page »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].