Abstracts tagged "neopterin"

Abstract Number: 0775 • ACR Convergence 2021
Decreased HDL Levels and Antioxidant Function in Juvenile Dermatomyositis
Amer Khojah¹, Arya Kadakia², Christina Charles-Schoeman³, Jacob Spitznagle⁴, Jennifer Wang³, Ani Shahbazian³, Gabrielle Morgan⁵ and Lauren Pachman⁶, ¹Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ²Ann and Robert H. Lurie Children’s Hospital, Chicago, IL, ³Department of Medicine, University of California, Los Angeles, Los Angeles, CA, ⁴Hospital for Special Surgery, New York, NY, ⁵Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Northwestern's Feinberg School of Medicine. Ann and Robert H. Lurie Children's Hospital of Chicago; Stanley Manne Children's Research Institute of Chicago, Lake Forest, IL
Background/Purpose: Juvenile Dermatomyositis (JDM) is the most common inflammatory myopathy of childhood and is characterized by chronic inflammation targeting muscle and skin. Older patients who…
Abstract Number: 0978 • ACR Convergence 2021
Immunological and Clinical Features of Untreated Juvenile Dermatomyositis Patients with Elevated Neopterin
Amer Khojah¹, Gabrielle Morgan² and Lauren Pachman³, ¹Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ²Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern's Feinberg School of Medicine. Ann and Robert H. Lurie Children's Hospital of Chicago; Stanley Manne Children's Research Institute of Chicago, Lake Forest, IL
Background/Purpose: Neopterin is a metabolic product of guanosine triphosphate, which is produced by macrophages upon stimulation with interferon-gamma from activated T helper cells. Despite the…