Abstracts tagged "Myositis"

Abstract Number: PP05 • ACR Convergence 2025
Mastering a Rare, Autoimmune Disease: My Journey Regaining Agency Through Education, Collaboration, and Community
Mustafa Shameem

Background/Purpose: After a complex diagnostic journey, my PCP working on a rheumatological theory ordered a myositis-specific autoantibody (MSA) panel. It revealed the presence of an…
Abstract Number: 2065 • ACR Convergence 2025
Pain in Idiopathic Inflammatory Myopathies: A Global Study of Patient Experience
Lekshmi Minikumari Rahulan¹, Shounak Ghosh², Manali Sarkar³, Didem Saygin⁴, Karin Lodin⁵, Rima Shrestha⁶, Tulika Chatterjee⁷, Jessica Day⁸, Samuel Shinjo⁹, Sreoshy Saha¹⁰, Lorenzo Cavagna¹¹, Masataka Kuwana¹², Vikas Agarwal¹³ and Latika Gupta¹⁴, ¹Sanjay Gandhi Postgraduate Institute of Medical sciences Lucknow, Lucknow, Uttar Pradesh, India, ²Department of Rheumatology, The Royal Wolverhampton NHS Trust, Wolverhampton, UK, Wolverhampton, United Kingdom, ³Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, ⁴Rush University Medical Center, Chicago, IL, ⁵Department of Gastro, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden, Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, ⁶Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Department of Research Services, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, ⁷Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, United States, Illinois, ⁸Walter and Eliza Hall Institute, Melbourne, Victoria, Australia, ⁹Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, ¹⁰Mymensingh Medical College, Mymensingh, Bangladesh, Mymensingh, Bangladesh, ¹¹Associate Professor in Rheumatology (Internal Medicine and Thepaeutics),University of Pavia, Pavia, Lombardy, Italy, Physician in Chief of Myositis Outpatients Clinic,Fondazione IRCCS Policlinico San Matteo, Pavia, Lombardia,Italy, Lombardia, Italy, ¹²Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ¹³Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, ¹⁴School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom
Background/Purpose: Pain remains a significant yet understudied aspect of idiopathic inflammatory myopathies (IIMs), considerably reducing quality of life despite advancements in immunomodulatory therapies. Information obtained…
Abstract Number: 1218 • ACR Convergence 2025
Social Determinants Shape Health Outcomes in Idiopathic Inflammatory Myopathies: Insights from Lived Experience of 1,252 Patients
Tsvetelina Velikova¹, Kostadin Kostadinov², Emilia Naseva³, Tamar Rubinstein⁴, Manali Sarkar⁵, Lavanya Mangla⁶, Joanna Makowska⁷, Raphael Micheroli⁸, Leandro ferreryra⁹, Linda Kobert¹⁰, Ioannis Parodis¹¹, Elena Nikiphorou¹², Samuel Shinjo¹³, Carlo Vinicio Caballero Uribe¹⁴, Vincenzo Venerito¹⁵, Vikas Agarwal¹⁶ and Latika Gupta¹⁷, ¹Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria, ²Department of Social Medicine and Public Health, Faculty of Public Health, Medical University, Plovdiv; Health and Quality of Life in a Green and Sustainable Environment Research Group, Strategic Research and Innovation Program for the Development of MU- Plovdiv, Medical University of Plovdiv, Environmental Health Division, Research Institute at Medical University of Plovdiv, Medical University of Plovdiv,, Plovdiv, Bulgaria, ³Faculty of Public Health, Medical University of Sofia, ¹⁵ Acad. Ivan Evstratiev Geshov, ¹⁶⁰⁶ Sofia; Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria, ⁴Albert Einstein College of Medicine, White Plains, NY, ⁵Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, ⁶Maulana Azad Medical College, ²-Bahadurshah Zafar Marg, New Delhi, New Delhi, India, ⁷Department of Rheumatology, Medical University of Lodz, Lodz, Poland, ⁸University Hospital Zurich, Zurich, Switzerland, ⁹HIBA, CABA, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁰The Myositis Association, Columbia, MD, ¹¹Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology, Stockholm, Sweden, ¹²King's College London, London, United Kingdom, ¹³Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, ¹⁴Department of Medicine, Hospital Universidad del Norte, Barranquilla, Atlantico, Colombi, Barranquilla, Colombia, ¹⁵Univeristy of Bari "Aldo Moro", Italy, Bari, Bari, Italy, ¹⁶Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, ¹⁷School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom
Background/Purpose: The impact of social determinants of health (SDoH)—including socioeconomic status, social support, and geographic context—on disease outcomes in idiopathic inflammatory myopathies (IIM) remains underexplored.…
Abstract Number: 1197 • ACR Convergence 2025
Genetic Profiling of Idiopathic Inflammatory Myopathies in Indian Patients Reveals Genotype-Phenotype Correlation
Bandana Jassal¹, Aishwarya Dhall¹, Mohammed Faruq², Danveer Bhadu¹, Uma Kumar¹ and Mehar Chand Sharma¹, ¹All India Institute of Medical Sciences, New Delhi, New Delhi, Delhi, India, ²Institute of Genomics and Integrative Biology, New Delhi, Delhi, India
Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are rare autoimmune muscle disorders with complex genetic underpinnings. Most genetic studies have focused on limited populations. This study explores…
Abstract Number: 0344 • ACR Convergence 2025
Inpatient Zoledronic Acid for Glucocorticoid-Induced Osteoporosis Prevention
Gregory Challener¹, Zandra E. Walton¹, Christine M. Parsons¹, Aakash V. Patel², Alex Tinianow³, Molly E. Griffin¹, Raisa Lomanto Silva³, Avira Som¹, Laura J. Yockey⁴, WuQiang Fan⁵, Sheila L. Arvikar¹ and Marcy Bolster⁶, ¹Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, ²Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Massachusetts General Hospital, Boston, MA, ⁴MGH, Charlestown, MA, ⁵Division of Endocrinology, Department of Medicine, Massachusetts General Hospital, Boston, ⁶Massachusetts General Hospital, Concord, MA
Background/Purpose: Glucocorticoids are widely used in rheumatology and are associated with increased fracture risk. The 2022 ACR Guideline for the Prevention and Treatment of Glucocorticoid-induced…
Abstract Number: 0284 • ACR Convergence 2025
Glucocorticoid Tapering and Relapse Risk in Anti-ARS Antibody-Positive Myositis: A Retrospective Study in a Single-Center Cohort Treated with Immunosuppressants
Ayaka Inoue¹, Takashi Yamane², Noriaki Yasuda³ and Takahisa Ohnishi¹, ¹Kakogawa Central City Hospital, Kakogawa, Japan., kakogawa-cho, kakogawa city, Hyogo, Japan, ²Kakogawa Central City Hospital, Kobe, Hyogo, Japan, ³Kakogawa Central City Hospital, Kakogawa, Japan
Background/Purpose: Anti–synthetase syndrome is generally responsive to glucocorticoid (GC) therapy, though relapse frequently complicates tapering. Prolonged GC use is associated with adverse events and decreased…
Abstract Number: PP01 • ACR Convergence 2025
When You Become the Story: A Journalist’s Approach to Managing Complex Care
Lindsay Guentzel
Background/Purpose: As a journalist, I’ve spent my career digging for answers. But when I became the story, I had to learn how to ask the…
Abstract Number: 2064 • ACR Convergence 2025
Kinematics Underlying IBM-induced Dysphagia
Kevin Renz Ambrocio¹, Vaidehi Kothari¹, Rohit Aggarwal², Anna Miles³, James L. Coyle¹, Eaman Alhassan⁴, Sandra Stinnett¹, David Lacomis¹, Lea Sayce¹ and Kendrea (Focht) Garand¹, ¹University of Pittsburgh, Pittsburgh, PA, ²University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA, ³The University of Auckland, Auckland, New Zealand, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: Dysphagia remains a key contributor to mortality in IBM due to its connection with aspiration pneumonia and malnutrition (Shelly et al., 2021). Compared to…
Abstract Number: 1217 • ACR Convergence 2025
Validation and clincial use of anti-MDA5 test – LIA versus ELISA
TING-YUAN LAN¹, pei-Hsinq lai², Tai-Ju Lee³, Ting-Wei Chang⁴, Kuan-Yen Lin⁵, Shao-Yu Pai⁶ and Ko-Jen Li⁷, ¹National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan, ²Taipei City Hospital, Taichung, Taiwan, ³National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan (Republic of China), ⁴National Taiwan University Hospital Hsinchu Branch, Taichung, Taiwan, ⁵National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu City, Taiwan (Republic of China), ⁶National Taiwan University Hospital, Taichung City, Taiwan (Republic of China), ⁷National Taiwan University Hospital, Taipei, Taiwan
Background/Purpose: Although immunoprecipitation (IP) remains the gold standard for detecting myositis autoantibodies, it is technically demanding and not widely available. Line immunoassay (LIA) has become…
Abstract Number: 1196 • ACR Convergence 2025
Prevalence of and Factors Associated with Chronic Opioid Use among Individuals with Inflammatory Myopathies
Anuya Natu¹, Haley Zimmerman², Kristin Wipfler³, Kaleb Michaud⁴, Yvonne Lee⁵ and Didem Saygin², ¹John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, ²Rush University Medical Center, Chicago, IL, ³FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵Northwestern University, Chicago, IL
Background/Purpose: Idiopathic inflammatory myopathies (IIM) can be associated with significant pain and functional impairment. While the use of opioids has been documented in other inflammatory…
Abstract Number: 0305 • ACR Convergence 2025
From Movement to Meaning: Exploring Physical Function in IBM with Actigraphy
Vaidehi Kothari¹, Eaman Alhassan², Kevin Renz Ambrocio¹, Bonny Rockette-Wagner³, Chester V. Oddis¹, Kendrea (Focht) Garand¹ and Rohit Aggarwal⁴, ¹University of Pittsburgh, Pittsburgh, PA, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Pittsburgh, PITTSBURGH, ⁴University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA
Background/Purpose: Inclusion body myositis (IBM) is a progressive and severe inflammatory muscle disease that primarily affects adults over 50 years of age. It presents with…
Abstract Number: 0283 • ACR Convergence 2025
The Performance of Rule-Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records
Ana Valle¹, Amy Vo², Rochelle Castillo¹, Yumeko Kawano³, Leah Santacroce³, Daniel Solomon⁴, Katherine Liao³ and Candace Feldman³, ¹Brigham and Women's Hospital, Brookline, MA, ²Harvard Medical School, Boston, ³Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Idiopathic inflammatory myopathies (IIM; including dermatomyositis, polymyositis, and inclusion body myositis) are heterogenous systemic inflammatory conditions that cause significant disability and morbidity. The study…
Abstract Number: 2673 • ACR Convergence 2025
Quantitative 18F-FDG PET/CT analysis reveals new patterns of muscle involvement and prognostic indicators in idiopathic inflammatory myopathies: beyond proximal muscle weakness
Fatma Basibuyuk¹, Melih Yigithan Bahadir², Gokce Kenar Artin², Amac Kiray², Recep Bekis² and İsmail Sari², ¹Dokuz Eylul University, Izmir, Turkey, ²Dokuz Eylül University, İzmir, Izmir, Turkey
Background/Purpose: To characterize muscle involvement in idiopathic inflammatory myopathies (IIMs) using detailed anatomical segmentation and volumetric 18F-FDG PET/CT analysis, and to evaluate the prognostic value…
Abstract Number: 2063 • ACR Convergence 2025
Linking PROMIS scores to disease severity and treatment in dermatomyositis: a patient-centered evaluation
Julie Paik¹, Andrea Young², Zuzana Bologna³, Will Kelly³, Chris Mecoli⁴, Jemima Albayda² and Lisa Christopher-Stine², ¹Johns Hopkins Rheumatology, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University, Baltimore, ⁴Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Dermatomyositis (DM) is a chronic inflammatory myopathy characterized by muscle weakness and skin rashes, yet its full impact on patient-reported outcomes remains under-explored. We…
Abstract Number: 1215 • ACR Convergence 2025
Remission Rates and Predictors in Idiopathic Inflammatory Myopathy Subtypes: Insights from a Single-Center Cohort
Nantakarn Pongtarakulpanit¹, Sidra Tahir², Varshapriya Suresh², Vaidehi Kothari³, Shiri Keret⁴, Eugenia Gkiaouraki⁵, Siamak Moghadam-Kia⁶, Vladimir Liarski⁷, Dana Ascherman⁵ and Rohit Aggarwal⁸, ¹Mahidol University, University of Pittsburgh, Bangkok, Thailand, ²Internal medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Pittsburgh Medical Center, Pittsburgh, ⁴Bnai Zion Medical Center, Atlit, Israel, ⁵University of Pittsburgh, Pittsburgh, PA, ⁶University of Pittsburgh Medical Center, Pittsburgh, PA, ⁷University of Pittsburgh School of Medicine, Pittsburgh, ⁸University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA
Background/Purpose: With therapeutic advances in idiopathic inflammatory myopathy (IIM), achieving remission has become an important goal. However, comprehensive data on remission, particularly across IIM subtypes,…

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