ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstracts tagged "Muscle strength"

  • Abstract Number: L10 • ACR Convergence 2022

    Efgartigimod Prevents Necrosis and Allows for Muscle Fiber Regeneration in a Humanized Mouse Model of Immune-mediated Necrotizing Myopathy (IMNM)

    Sarah Julien1, Emma Briand1, Bas van der Woning2, Leentje de ceuninck3, Rachid zoubari1, olivier benveniste4, laurent drouot1 and olivier boyer5, 1INSERM U1234, PAn’THER FOCIS Center of Excellence, Rouen, France, 2argenx, Boston, MA, 3argenx, Ghent, Belgium, 4AP-HP, Pitié-Salpêtrière University Hospital, Department of Internal Medicine and Clinical Immunology, Paris, France, 5INSERM U1234, PAn’THER FOCIS Center of Excellence; Rouen University Hospital, Department of Immunology and Biotherapy, Rouen, France

    Background/Purpose: Immune-mediated necrotizing myopathy (IMNM) is a severe form of myositis characterized by muscle weakness and elevated creatine kinase levels in serum. The most frequent…
  • Abstract Number: 0041 • ACR Convergence 2022

    Modeling Juvenile Dermatomyositis with Engineered Human Skeletal Muscle: Effects of Type I Interferonβ and Janus Kinase Inhibitors

    Lauren Covert1, George Truskey2 and Jeffrey Dvergsten1, 1Duke University Hospital, Durham, NC, 2Duke University, Durham, NC

    Background/Purpose: Upregulation of Type I interferons (IFN I), including IFNβ, is a hallmark of adult and juvenile dermatomyositis (JDM), but its role in pathogenesis is…
  • Abstract Number: 0158 • ACR Convergence 2022

    Effect of Type I IFN on Mitochondria and Muscle Weakness in Myositis

    Melissa Morales, Joanna Parkes, Sabrina Narvesen and Rita Spathis, Department of Pharmaceutical Sciences, Binghamton University, Binghamton, NY

    Background/Purpose: Muscle weakness is a hallmark of autoimmune myositis. The mechanisms that contribute to muscle weakness are currently unknown. The observed ineffectiveness after immunomodulatory treatment…
  • Abstract Number: 0847 • ACR Convergence 2022

    Association of Frontal Plane Trunk Motion During Gait with Abductor Strength, Fatigue, and Physical Activity in Women with Hip Osteoarthritis

    Sanghamitra Nayak1, Burcu Aydemir2, Chun-Hao Huang3 and Kharma Foucher1, 1University of Illinois at Chicago, Chicago, IL, 2Northwestern University, Chicago, IL, 3Northeastern University, Boston, MA

    Background/Purpose: We have previously reported that fatigue and hip abductor weakness are associated with reduced physical activity (PA) in women with hip osteoarthritis (OA). We…
  • Abstract Number: 1886 • ACR Convergence 2022

    Statin-induced Immune-mediated Miopathy: Treatment with Glucocorticoid-free Protocols and Role of Muscle Biopsy in the Follow-up

    David Martínez-López1, Piotr Szczęsny2, Inger Nennesmo3, Karina Gheorghe4, Antonella Notarnicola5, Helene Alexanderson6, Ingrid Lundberg7 and Maryam Dastmalchi8, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 3Department of Pathology, Karolinska University Hospital,Pathology, Karolinska University Hospital., Stockholm, Sweden, 4Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet. Rheumatology, Karolinska University Hospital Stockholm, Sweden. Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 5Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 6Karolinska Institutet, Stockholm, Sweden, 7Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, 8Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a recently identified autoimmune condition associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies, characterized by progressive muscle weakness leading…
  • Abstract Number: 0694 • ACR Convergence 2021

    Glucagon-like Peptide-1 Receptor Agonist Suppresses Muscle Fiber Necroptosis and Muscle Inflammation and Ameliorates Muscle Weakness in Experimental Polymyositis

    Mari Kamiya1, Fumitaka Mizoguchi1, Hirokazu Sasaki2, Natsuka Umezawa1 and Shinsuke Yasuda3, 1Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 2Department of Lifetime Clinical Immunology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 3Tokyo Medical and Dental University (TMDU), Tokyo, Japan

    Background/Purpose: While glucocorticoids (GC) are the cornerstone of the treatment for polymyositis (PM), GC-induced myopathy is inevitable, which deteriorates muscle weakness. Therefore, novel therapeutic strategy…
  • Abstract Number: 0710 • ACR Convergence 2021

    Patients with Recent Onset, Active Polymyositis (PM), Dermatomyositis (DM) and Antisynthetase Syndrome (ASS) Have Reduced Muscle Endurance but Not Reduced Muscle Strength Compared to Patients with Established, Low-active Disease

    Kristofer Andreasson1 and Helene Alexanderson2, 1Karolinska Institute, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: To analyze for differences in quadriceps maximal isometric voluntary contraction (MVIC), muscle endurance (ME), muscle mass and fat mass (m. vastus lateralis, mid-thigh) in…
  • Abstract Number: 1664 • ACR Convergence 2021

    Changes in Physical Function Were Not Associated with Clinically Important Changes in Muscle Strength or Physical Performance over Time – A Cohort Study

    Rafaela Espírito Santo1, Joshua Baker2, Jordana Silva3, Lidiane Filippin4, Juliana Portes1, Claiton Brenol1, Rafael Chakr5 and Ricardo Xavier6, 1Hospital de Clínicas de Porto Alegre, Laboratório de Doenças Autoimunes, Serviço de Reumatologia, Porto Alegre, Brazil; Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Porto Alegre, Brazil, 2University of Pennsylvania, Philadelphia, PA, 3Institute of musculoskeletal medicine, University Hospital Munster, Munster, Germany, 4Universidade La Salle, Canoas, Brazil, 5Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 6Departamento de Reumatologia, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Background/Purpose: The Health Assessment Questionnaire Disability Index (HAQ) is negatively associated with muscle strength by handgrip test and positively associated with physical performance by timed…
  • Abstract Number: 0221 • ACR Convergence 2021

    Trunk Movement Compensation Is Associated with Physical Performance Measures and Fatigue Deficits in Hip Osteoarthritis

    Jesse Christensen1, David Quammen2, Justin Rigby2, Cory Christiansen3 and Jennifer Stevens-Lapsley3, 1VA Salt Lake City Health Care System, Salt Lake City, UT, 2University of Utah, Salt Lake City, UT, 3Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO

    Background/Purpose: Movement compensation is common in people with hip osteoarthritis (HOA) and a biomarker of physical performance and muscle strength deficits in older adults. Inertial…
  • Abstract Number: 0563 • ACR Convergence 2020

    Relation of Pain Sensitization to Isokinetic Knee Extension Torque: The MOST Study

    Patrick Corrigan1, Tuhina Neogi2, Laura Frey Law3, Neil Segal4, Michael Nevitt5, Beth Lewis6 and Joshua Stefanik1, 1Northeastern University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3University of Iowa, Iowa City, IA, 4University of Kansas Medical Center, Iowa City, IA, 5Department of Epidemiology and Biostatistics, University of California San Francisco, Orinda, CA, 6University of Alabama at Birmingham, Birmingham

    Background/Purpose: Central and local alterations in nociception are related to heightened pain severity and can be present in people who have knee osteoarthritis (OA). Yet,…
  • Abstract Number: 1916 • ACR Convergence 2020

    KZR-616, a First-in-class Selective Inhibitor of the Immunoproteasome, Ameliorates Polymyositis in a Murine Model

    Marta Del Rio Oliva1, Michael Basler1, Darrin Bomba2, Diana Lam2, Jennifer Brandl2, Christopher Kirk2 and Marcus Groettrup1, 1University of Konstanz, Konstanz, Germany, 2Kezar Life Sciences, Inc, San Francisco, CA

    Background/Purpose: Polymyositis (PM) is a chronic autoimmune inflammatory myopathy affecting striated muscles and resulting in muscle weakness. PM is a rare disease, and there are…
  • Abstract Number: 599 • 2019 ACR/ARP Annual Meeting

    Muscle Physical Properties in Young Adult Axial Spondyloarthritis Patients, the MyoSpA Study

    Fernando Pimentel-Santos1, Agna Neto 2, Lúcia Domingues 3, Atlas Sardoo 3, Santiago Rodrigues-Manica 1, Rita Pinheiro Torres 4, Carolina Crespo 5, Alexandre Sepriano 6, Sofia Ramiro 7, Kalyani Nair 8, Júlia Costa 9, Patrícia Gomes-Alves 10, Alfonse Masi 11 and Jaime Branco 1, 1CEDOC, NOVA-Medical School | Hospital Egas Moniz, CHLO, Lisbon, Lisbon, Portugal, 2Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon; Hospital Central do Funchal, Madeira., Lisbon, Portugal, 3CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon, Lisbon, Portugal, 4Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon., Lisbon, Portugal, 5CEDOC, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal, Lisbon, Portugal, 6Leiden University Medical Center, Leiden, Netherlands, 7Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, 8Bradley University and University of Illinois College of Medicine at Peoria, Illinois, USA, Peoria, IL, 9Instituto de Tecnologia Química e BiológicaAntónio Xavier, Universidade NOVA de Lisboa, Av. República, 2780-157 Oeiras, Portugal, Oeiras, Portugal, 10Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, 11University of Illinois College of Medicine at Peoria and Bradley University, Peoria Illinois, USA, Peoria, IL

    Background/Purpose: An important mechanism regarding axial spondyloarthritis (axSpA) susceptibility and progression is the biomechanical concept, suspected from axial myofascial hypertonicity and stiffness in ankylosing spondylitis…
  • Abstract Number: 380 • 2018 ACR/ARHP Annual Meeting

    A New Tool to Assess Muscle Strength in Polymyositis and Dermatomyositis: Hand-Held Dynamometry

    Didem Saygin1, Chester V. Oddis2, Siamak Moghadam-Kia3, Diane Koontz4, Nicole Marie Neiman3 and Rohit Aggarwal5, 1Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Division of Rheumatology and Clinical Immunology, Department of Medicine, Unviersity of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA, 3Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Internal Medicine Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Medicine / Rheumatology, University of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) is a group of systemic autoimmune diseases characterized by proximal muscle weakness, which is often assessed clinically using manual muscle…
  • Abstract Number: 398 • 2018 ACR/ARHP Annual Meeting

    Muscle Function and Health-Related Quality of Life in Patients with Polymyositis and Dermatomyositis

    Kristofer Andreasson1, Li Alemo Munters1,2 and Helene Alexanderson3,4, 1Karolinska University Hospital, Function Area Occupational therapy and Physical therapy, Stockholm, Sweden, 2Swedish Rheumatism Association, Stockholm, Sweden, 3Department of NVS, Division of Physical Therapy, Karolinska Institutet, Huddinge, Sweden, 4Function Area Occupational therapy & Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Poly- and dermatomyositis (PM/DM) are idiopathic inflammatory muscle diseases characterized by reduced muscle function. Oral glucocorticoids and DMARD’s are the usual treatment options and…
  • Abstract Number: 418 • 2018 ACR/ARHP Annual Meeting

    Dose-Response Relationship between Neuromuscular Electrical Stimulation and Muscle Function in Patients with Rheumatoid Arthritis

    Gustavo J. Almeida1, Samannaaz S. Khoja2 and Sara R. Piva1, 1Physical Therapy, University of Pittsburgh, Pittsburgh, PA, 2Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Neuromuscular electrical stimulation (NMES) is a viable intervention to improve impaired muscle function of patients with rheumatoid arthritis (RA). However, there is limited evidence…
  • 1
  • 2
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2023 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences