Abstracts tagged "Muscle strength"

Abstract Number: 0563 • ACR Convergence 2020
Relation of Pain Sensitization to Isokinetic Knee Extension Torque: The MOST Study
Patrick Corrigan¹, Tuhina Neogi², Laura Frey Law³, Neil Segal⁴, Michael Nevitt⁵, Beth Lewis⁶ and Joshua Stefanik¹, ¹Northeastern University, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³University of Iowa, Iowa City, IA, ⁴University of Kansas Medical Center, Iowa City, IA, ⁵Department of Epidemiology and Biostatistics, University of California San Francisco, Orinda, CA, ⁶University of Alabama at Birmingham, Birmingham
Background/Purpose: Central and local alterations in nociception are related to heightened pain severity and can be present in people who have knee osteoarthritis (OA). Yet,…
Abstract Number: 1916 • ACR Convergence 2020
KZR-616, a First-in-class Selective Inhibitor of the Immunoproteasome, Ameliorates Polymyositis in a Murine Model
Marta Del Rio Oliva¹, Michael Basler¹, Darrin Bomba², Diana Lam², Jennifer Brandl², Christopher Kirk² and Marcus Groettrup¹, ¹University of Konstanz, Konstanz, Germany, ²Kezar Life Sciences, Inc, San Francisco, CA
Background/Purpose: Polymyositis (PM) is a chronic autoimmune inflammatory myopathy affecting striated muscles and resulting in muscle weakness. PM is a rare disease, and there are…
Abstract Number: 599 • 2019 ACR/ARP Annual Meeting
Muscle Physical Properties in Young Adult Axial Spondyloarthritis Patients, the MyoSpA Study
Fernando Pimentel-Santos¹, Agna Neto ², Lúcia Domingues ³, Atlas Sardoo ³, Santiago Rodrigues-Manica ¹, Rita Pinheiro Torres ⁴, Carolina Crespo ⁵, Alexandre Sepriano ⁶, Sofia Ramiro ⁷, Kalyani Nair ⁸, Júlia Costa ⁹, Patrícia Gomes-Alves ¹⁰, Alfonse Masi ¹¹ and Jaime Branco ¹, ¹CEDOC, NOVA-Medical School | Hospital Egas Moniz, CHLO, Lisbon, Lisbon, Portugal, ²Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon; Hospital Central do Funchal, Madeira., Lisbon, Portugal, ³CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon, Lisbon, Portugal, ⁴Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon., Lisbon, Portugal, ⁵CEDOC, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal, Lisbon, Portugal, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, ⁸Bradley University and University of Illinois College of Medicine at Peoria, Illinois, USA, Peoria, IL, ⁹Instituto de Tecnologia Química e BiológicaAntónio Xavier, Universidade NOVA de Lisboa, Av. República, 2780-157 Oeiras, Portugal, Oeiras, Portugal, ¹⁰Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, ¹¹University of Illinois College of Medicine at Peoria and Bradley University, Peoria Illinois, USA, Peoria, IL
Background/Purpose: An important mechanism regarding axial spondyloarthritis (axSpA) susceptibility and progression is the biomechanical concept, suspected from axial myofascial hypertonicity and stiffness in ankylosing spondylitis…
Abstract Number: 380 • 2018 ACR/ARHP Annual Meeting
A New Tool to Assess Muscle Strength in Polymyositis and Dermatomyositis: Hand-Held Dynamometry
Didem Saygin¹, Chester V. Oddis², Siamak Moghadam-Kia³, Diane Koontz⁴, Nicole Marie Neiman³ and Rohit Aggarwal⁵, ¹Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Division of Rheumatology and Clinical Immunology, Department of Medicine, Unviersity of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA, ³Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Internal Medicine Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁵Medicine / Rheumatology, University of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: Idiopathic inflammatory myopathies (IIM) is a group of systemic autoimmune diseases characterized by proximal muscle weakness, which is often assessed clinically using manual muscle…
Abstract Number: 398 • 2018 ACR/ARHP Annual Meeting
Muscle Function and Health-Related Quality of Life in Patients with Polymyositis and Dermatomyositis
Kristofer Andreasson¹, Li Alemo Munters^1,2 and Helene Alexanderson^3,4, ¹Karolinska University Hospital, Function Area Occupational therapy and Physical therapy, Stockholm, Sweden, ²Swedish Rheumatism Association, Stockholm, Sweden, ³Department of NVS, Division of Physical Therapy, Karolinska Institutet, Huddinge, Sweden, ⁴Function Area Occupational therapy & Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital, Stockholm, Sweden
Background/Purpose: Poly- and dermatomyositis (PM/DM) are idiopathic inflammatory muscle diseases characterized by reduced muscle function. Oral glucocorticoids and DMARD’s are the usual treatment options and…
Abstract Number: 418 • 2018 ACR/ARHP Annual Meeting
Dose-Response Relationship between Neuromuscular Electrical Stimulation and Muscle Function in Patients with Rheumatoid Arthritis
Gustavo J. Almeida¹, Samannaaz S. Khoja² and Sara R. Piva¹, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Neuromuscular electrical stimulation (NMES) is a viable intervention to improve impaired muscle function of patients with rheumatoid arthritis (RA). However, there is limited evidence…
Abstract Number: 913 • 2018 ACR/ARHP Annual Meeting
Risk Factors for Knee Pain Exacerbation on Walking: A within-Person Knee-Matched Study
Qiang Liu^1,2, David J. Hunter³, Manuela Ferreira⁴, Barton L Wise⁵, Ke Tao¹, Yuqing Zhang⁶ and Jianhao Lin¹, ¹Arthritis Clinic and Research Center, Peking University People's Hospital, Beijing, China, ²Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁴Institute of Bone and Joint Research | The Kolling Institute, Sydney Medical School, Sydney, Australia, ⁵Orthopaedics, Internal Medicine, University of California, Davis School of Medicine, Sacramento, CA, ⁶Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA
Background/Purpose: Pain exacerbation on walking is common among patients with knee osteoarthritis and often lead to activity avoidance. To date, few risk factors for pain…
Abstract Number: 2332 • 2018 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Effect´s on Bone Mass and Muscle
María Lorena Brance¹, Bernardo A Pons-Estel², Javier Quagliatto³, Marisa Jorfen⁴, Noel Cortese⁴, Guillermo Berbotto⁵, Juan Carlos Raggio⁶, Juan Soldano³, Mariano Palatnik¹, Ignacio Chavero¹, Carolina Dieguez¹, Silvana Di Gregorio⁷ and Lucas Ricardo Brun⁸, ¹Centro de Reumatología, Rosario, Argentina, ²Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Rosario, Argentina, ³Hospital Provincial, Rosario, Argentina, ⁴Municipalidad de Rosario, Rosario, Argentina, ⁵Hospital Escuela Eva Perón, Granadero Baigorria, Argentina, Granadero Baigorria, Argentina, ⁶Hospital Eva Perón, Granadero Baigorria, Argentina, ⁷Centre Medic Cetir, Barcelona, Spain, ⁸School of Medicine. Rosario National University, Bone Biology Laboratory, Rosario, Argentina
Background/Purpose: Rheumatoid arthritis (RA) is a progressive auto-immune disease characterized by chronic inflammation which leads to joint deformity and disability. However, the bone and muscle…
Abstract Number: 1541 • 2016 ACR/ARHP Annual Meeting
Frailty Is Associated with Decreased Physical Function in Adults with Rheumatoid Arthritis
James Andrews¹, Ken Covinsky², Catherine Hough¹, Laura Trupin³, Edward H. Yelin³ and Patricia P. Katz³, ¹Medicine, University of Washington, Seattle, WA, ²Medicine, University of California San Francisco, San Francisco, CA, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Reduced physical function and health-related quality of life remain common in Rheumatoid Arthritis (RA), and further studies are needed that examine potential, novel determinates…
Abstract Number: 217 • 2014 ACR/ARHP Annual Meeting
The Relationship of Quadriceps and Hamstrings Intramuscular Fat and Lean Muscle with Power in Women with Knee Osteoarthritis
Michael J. Davison¹, Monica R. Maly², Karen A. Beattie³, Peter J. Keir⁴ and Jonathan D. Adachi⁵, ¹Medical Sciences, McMaster University, Hamilton, ON, Canada, ²School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, ³Medicine, McMaster University, Hamilton, ON, Canada, ⁴Kinesiology, McMaster University, Hamilton, ON, Canada, ⁵Division of Rheumatology, McMaster University, Hamilton, ON, Canada
Background/PurposeReduced quadriceps and hamstrings strength is a risk factor for knee osteoarthritis (OA). This strength loss is partly due to the loss of lean muscle…
Abstract Number: 2096 • 2013 ACR/ARHP Annual Meeting
Impaired Shoulder-Arm Mobility and Muscle Function In Patients With Systemic Sclerosis
Helene Alexanderson¹, Fia Bringby², Annica Nordin³, Lena Björnådal⁴, Elisabet Svenungsson⁵ and Carina Boström⁶, ¹Department of Neurobiology, Care Science and Society, Division of Physiotherapy, Division of Physiotherapy, Karolinska Institutet, Huddinge, Stockholm, Sweden, ²Capio Arthro Clinic, Stockholm, Sweden, ³Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, ⁴Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Medicine, Unit of Rheumatology, Karolinska Institutet, Stockholm, Sweden, ⁶Department of Neurobiology, Care Sciences and Society,, Division of Physiotherapy, Karolinska Institutet Huddinge, Stockholm, Sweden
Background/Purpose: Patients with systemic sclerosis (SSc) have reduced hand function and self-reported limitations in daily activities. Few studies have explored limitations in shoulder-arm mobility and…
Abstract Number: 2054 • 2013 ACR/ARHP Annual Meeting
Efficacy and Safety Of Low-Intensity Resistance Training Combined With Vascular Occlusion In Polymyositis and Dermatomyositis
Melina Mattar¹, Luiz A. Perandini¹, Thalita Dassouki², Samuel K. Shinjo¹, Bruno Gualano³, Hamilton Roschel³, Fernanda R. Lima⁴ and Ana Lucia S. Pinto¹, ¹University of Sao Paulo, Rheumatology Division, LACRE, Sao Paulo, Brazil, ²Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ³University of Sao Paulo, School of Physical Education and Sport, Sao Paulo, Brazil, ⁴University of Sao Paulo, Rheumatology Division, Sao Paulo, Brazil
Background/Purpose: Previous studies have demonstrated that low-intensity resistance training combined with vascular occlusion (VO) improves muscle strength to the magnitude of traditional high-intensity resistance training…
Abstract Number: 252 • 2013 ACR/ARHP Annual Meeting
The Association Of Knee Buckling With Vibratory Perception and Muscle Strength: The Multicenter Osteoarthritis Study
Najia Shakoor¹, David T. Felson², Jingbo Niu³, Neil A. Segal⁴, Uyen Sa D.T. Nguyen⁵, Jasvinder A. Singh⁶ and Michael C. Nevitt⁷, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁵Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁶Department of Medicine, University of Alabama, Tuscaloosa, AL, ⁷Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA
Background/Purpose: Knee buckling (“giving way”) is a common symptom in knee osteoarthritis (OA). Yet, little is known regarding risk factors for buckling. Knee buckling has…
Abstract Number: 208 • 2012 ACR/ARHP Annual Meeting
Outcome of Muscle Function and Disease Activity in Patients Recently Diagnosed with Polymyositis and Dermatomyositis – Preliminary Results of a 1-Year Follow-up Registry Study
Helene Alexanderson¹, Jenny Bergegård², Christina Ottosson³, Maryam Dastmalchi⁴ and Ingrid E. Lundberg⁵, ¹Dept of Neuroscience, Care Science and Society, Karolinska Institutet, Stockholm, Sweden, ²Department of Physical Therapy, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Solna, Stockholm, Sweden, ³Department of Medicine, Rheumatology Unit, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden., Stockholm, Sweden, ⁴Department of Medicine, Karolinska University Hospital, Department of Medicine, Solna, Unit of Rheumatology, Stockholm, Sweden, ⁵Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Most patients with polymyositis (PM) and dermatomyositis (DM) develop sustained muscle impairment. The aim of this study was to evaluate the muscle endurance (Functional…
Abstract Number: 1947 • 2012 ACR/ARHP Annual Meeting
Muscle Wasting in HTNFtg Mice, an Animal Model for Rheumatoid Arthritis, Due to Increased Cathepsin L and LC3B Expression
Martin Willburger¹, Birgit Niederreiter¹, Ewald Unger², Josef S. Smolen³, Kurt Redlich¹ and Silvia Hayer¹, ¹Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Center for Medical Physics and Biomedicla Engineering, Medical University of Vienna, Vienna, Austria, ³Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: To investigate the impact of systemic inflammation on skeletal muscles in human tumor necrosis factor transgenic (hTNFtg) animals. Methods: We isolated triceps surae, quadriceps,…