ACR Meeting Abstracts

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Abstracts tagged "Muscle strength"

  • Abstract Number: 2452 • ACR Convergence 2024

    Multimodal Ultrasound in the Assessment of Sarcopenia-related Muscle Involvement in Patients with Systemic Sclerosis: A Multicentric Study

    Riccardo Bixio1, Maria Giovanna Lommano2, Seda Colak3, Sonia farah4, Francesca Pistillo5, Richard Wakefield6, Fausto Salaffi4, Stefano Di Donato7, Ombretta Viapiana5, Rossella De Angelis8, Maurizio Rossini5, Edoardo Cipolletta9, Emilio Filippucci10, Luca Idolazzi5, Francesco Del Galdo11 and Andrea Di Matteo12, 1University of Verona, Verona, Verona, Italy, 2Università Politecnica delle Marche, Jesi, Italy, 3Gulhane Training and Research Hospital, Ankara, Turkey, 4Polytechnic University of Marche, Jesi (AN), Italy, 5Rheumatology Unit, University of Verona, Verona, Italy, 6NIHR Leeds Biomedical Research Centre, Leeds, UK., Leeds, United Kingdom, 7Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 8Polytechnic University of Marche, Ancona, Italy, Ancona, Italy, 9Polytechnic University of Marche, Ancona, Italy, 10Rheumatology Unit, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Jesi, Ancona, Italy, Jesi, Italy, 11University of Leeds, Leeds, United Kingdom, 12Faculty of Medicine and Health, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom

    Background/Purpose: Patients with systemic sclerosis (SSc) are at an increased risk of sarcopenia and muscle involvement. This study aims to describe the ultrasound findings of…
  • Abstract Number: 0175 • ACR Convergence 2024

    Do Knee Strength and Pain Relate to Developing Stair Climbing Difficulty for Knee Osteoarthritis?

    Jason Jakiela1, Yvonne Golightly2, Sydney Liles3, Judy Foxworth4 and Daniel White5, 1Winston-Salem State University, Winston-Salem, NC, 2University of Nebraska Medical Center, Omaha, NE, 3University of Delaware, Elkton, MD, 4Winston-Salem State University, Elon, NC, 5University of Delaware, Newark, DE

    Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and stair climbing difficulty is often the first-reported limitation. Previous work…
  • Abstract Number: 0489 • ACR Convergence 2024

    Use of Chair Sit-to-Stand as a Pragmatic Alternative to Assess Frailty in Rheumatoid Arthritis

    Hannah Brubeck1, Kylie Riggles2, Riley Bass3, Elizabeth Wahl4, James Andrews5, Namrata Singh6, ariela orkaby7, Joshua Baker8, Patti Katz9, Dolores Shoback10, Jose Garcia11 and Katherine Wysham12, 1VA Puget Sound Health Care System, Seattle, WA, 2VA Puget Sound Health Care System, Bellevue, WA, 3VA Puget Sound Health Care System, Seattle, 4VA Puget Sound Healthcare System, Seattle, WA, 5University of Alabama at Birmingham, Birmingham, AL, 6University of Washington, Bellevue, WA, 7New England VA Geriatric Research Education and Clinical Center/Boston VA/Division of Aging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 8University of Pennsylvania, Philadelphia, PA, 9UCSF, San Rafael, CA, 10San Francisco VA/University of California, San Francisco, San Francisco, CA, 11VA Puget Sound Health Care System/University of Washington, Seattle, WA, 12VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA

    Background/Purpose: Frailty occurs earlier in people with rheumatoid arthritis (RA) than in the general population and is associated with poor health outcomes1, making it important…
  • Abstract Number: 0560 • ACR Convergence 2024

    Association Between a Self-Report Screening Tool for Sarcopenia (SARC-F) and Disease Activity, Muscle Strength and Muscle Power Measures, Patient-Reported Outcomes and Body Composition in Patients with Spondyloarthritides

    Iuliia Kononenko1, Marius Bedei2, Bjoern Buehring3, Xenofon Baraliakos4 and Uta Kiltz5, 1Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Bochum, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Herne, Germany, 3Bergisches Rheuma-Zentrum, Wuppertal, Germany, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany

    Background/Purpose: The SARC-F is a self-report screening tool for sarcopenia (Sar) used to identify individuals at risk for poor functional outcomes [1]. The aim of this study was…
  • Abstract Number: 1182 • ACR Convergence 2024

    Assessing Male Pelvic Floor Contractions Using a Novel External Pressure Device and Ultrasound

    Benedetto Giardulli1, Mirko Job1, Filippo Recenti1, Gaia Leuzzi1, Alessandro Muda2, Ottavia Buccarella1 and Marco Testa1, 1University of Genova, Savona, Italy, 2Lavagna Hospital - Radiology Dept., Genova, Italy

    Background/Purpose: Men with rheumatic and musculoskeletal diseases (RMD) often experience sexual dysfunctions such as pelvic floor pain and erectile dysfunctions, which affect their sexual well-being.…
  • Abstract Number: 2125 • ACR Convergence 2024

    Strengthening Fracture Risk Prediction in Rheumatoid Arthritis: Integrating a Self-report Sarcopenia Screening Tool (SARC-F) and Fracture Risk Assessment Tool (FRAX) Scores

    Ana Rodriguez-Flores1, Ana Cecilia Bardan-Inchaustegui2, Mara Ponce2, Galilea Rodriguez3, Anahí Carrazco Chapa4, Valeria Monserrat De Hoyos-Perez5, Gilberto J Cervantes Charles5, Alma Damian Peñaloza5, Cinthia Maribel Cortez Lopez5, CASSANDRA SKINNER TAYLOR6, Roberto Negrete Lopez5, Jesus Cardenas-de la Garza2 and Dionicio Galarza-Delgado7, 1Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 2Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 3Hospital Universitario "Dr Jose Eleuterio Gonzalez", Monterrey, Mexico, 4Hospital Universitario Jose Eleuterio Gonzalez, UANL, Rheumatology, Monterrey, Mexico, Monterrey, Mexico, 5Hospital Universitario Dr José Eleuterio González, Monterrey, Nuevo León, Mexico, 6HOSPITAL UNIVERSITARIO DR JOSE ELEUTERIO GONZALEZ, MONTERREY, Mexico, 7UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) patients have an increased risk of fractures due to factors such as chronic inflammation, use of glucocorticoids, and reduced muscle mass.…
  • Abstract Number: 0294 • ACR Convergence 2023

    Tofacitinib Treatment in Rheumatoid Arthritis Is Associated with Increased Lower Limb Muscle Volume: The Rheumatoid Arthritis and Muscle (RAMUS) Study

    Joshua L Bennett1, Kieren G Hollingsworth2, Arthur Pratt3, Maha Egail3, Catherine Feeney4, Valeria Di Leo4, Robert W Taylor4, Richard Dodds5, Amy E Anderson3, Avan Aihie Sayer5 and John Isaacs6, 1Immunity and Inflammation Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle upon Tyne, United Kingdom, 2Innovation Methodology and Application Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 3Immunity and Inflammation Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 4Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 5AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, 6Translational and Clinical Research Institute, Newcastle University and Musculoskeletal Unit, Newcastle Hospitals, Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom

    Background/Purpose: Approximately 1 in 4 people with RA have sarcopenia, defined as generalised loss of skeletal muscle (SKM) strength and mass, resulting in an increased…
  • Abstract Number: 0302 • ACR Convergence 2023

    Remission in Anti-HMGCR Positive Immune-mediated Necrotizing Myopathy Without the Use of Glucocorticoids: A Multicentric Study of 24 Patients

    David Martinez-Lopez1, Cristina Corrales Selaya2, Diana Prieto-Peña2, Piotr Szczesny3, Antonella Notarnicola4, Ricardo Blanco5, Ingrid Lundberg6 and Maryam Dastmalchi6, 1Hospital de Sierrallana, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 4Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 6Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden

    Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. This condition is characterized by progressive…
  • Abstract Number: 0640 • ACR Convergence 2023

    Multidisciplinary and Multiparametric Evaluation of Sarcopenia in Patients with Systemic Sclerosis

    Marco Di Battista1, Alessandra Rossi1, Gaia Pisano1, Riccardo Morganti2, Alessandra Della Rossa3 and Marta Mosca4, 1Rheumatology Unit, University of Pisa, Pisa, Italy, 2Section of Statistics, University of Pisa, Pisa, Italy, 3University of Pisa, Rheumatology Unit, Pisa, Italy, 4Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

    Background/Purpose: Systemic sclerosis (SSc) is a chronic autoimmune disease with a heterogeneous clinical expression that heavily affects the functionality and quality of life of patients.…
  • Abstract Number: 0664 • ACR Convergence 2023

    Quantitative Hand Held Dynamometry to Assess Muscle Strength in Scleroderma Associated Myopathy

    Julie Paik1, Christopher Mecoli2, Anshula Nallapati1, Ami Shah3, Fred Wigley4, Zsuzsanna McMahan5 and Laura Hummers1, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Ellicott City, MD, 4Department of Rheumatology, Johns Hopkins Medicine, Baltimore, MD, 5Johns Hopkins Rheumatology, Lutherville, MD

    Background/Purpose: Manual muscle strength testing can be challenging in SSc associated myopathy (SSc-AM) due to contractures or skin tightening. Since there is currently no validated…
  • Abstract Number: 1177 • ACR Convergence 2023

    Anti-HMGCR Autoantibody Levels in the Follow-up of Statin-induced Immune-mediated Necrotizing Myopathy: Multicentric Study of 24 Patients

    David Martinez-Lopez1, Cristina Corrales Selaya2, Diana Prieto-Peña2, Piotr Szczesny3, Antonella Notarnicola4, Marcos Lopez-Hoyos5, Ricardo Blanco6, Ingrid Lundberg7 and Maryam Dastmalchi7, 1Hospital de Sierrallana, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 4Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 5Marques de Valdecilla University Hospital-IDIVAL, Santander, Spain, 6Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 7Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden

    Background/Purpose: Statin-induced immune-mediated necrotizing myopathy (IMNM) is associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. It is characterized by elevated creatine kinase (CK) levels, and severe muscle…
  • Abstract Number: 1182 • ACR Convergence 2023

    Treatment Trajectories and Patient Outcomes in Idiopathic Inflammatory Myopathies

    Kristin Wipfler1, Michael Feely2, Gulsen Ozen3, Urbano Sbarigia4, Federico Zazzetti5, Anna Sheahan6, Iris Lin7, Evo Alemao8 and Kaleb Michaud2, 1FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University of Nebraska Medical Center, Bellevue, NE, 4Janssen Pharmaceutica, Beerse, Belgium, 5Janssen Research & Development, LLC, Spring House, PA, 6Janssen, Raleigh, NC, 7Janssen, Horsham, PA, 8Janssen Pharmaceuticals, New Hope, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are rare, heterogeneous diseases characterized by chronic skeletal muscle inflammation and weakness. Initial conventional therapy is based on expert opinion…
  • Abstract Number: 1878 • ACR Convergence 2023

    MRI-determined Intramuscular Fat Changes During Oral Glucocorticoid Treatment: Findings from a Feasibility Study

    Thurkka Rajeswaran1, Emma Harris2, hannah Mathieson1, John Biglands3, Paul Stewart1, Ai Lyn Tan1 and Sarah Mackie4, 1University of Leeds, Leeds, United Kingdom, 2The Open University, Milton Keynes, United Kingdom, 3NIHR Leeds Biomedical Research Centre and Medical Physics and Engineering , Leeds Teaching Hospitals NHS Trust Leeds, Leeds, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Oral glucocorticoid therapy has many adverse effects including insulin resistance and myopathy. Long-term glucocorticoid therapy causes a "sarcopenic obesity" phenotype of adiposity with muscle…
  • Abstract Number: 1914 • ACR Convergence 2023

    Intravenous Immunoglobulins in the Treatment of Idiopathic Inflammatory Myopathies in a Region of Northern Spain: Analysis by Subtypes

    Cristina Corrales Selaya1, David Martínez-Lopez2, Diana Prieto-Peña1, Fabricio Benavides1, Jose Luis Martin-Varillas3 and Ricardo Blanco4, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital de Laredo, Laredo, Spain, 4Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of diseases characterised mainly by the presence of inflammation and muscle weakness. The main subtypes of…
  • Abstract Number: 1957 • ACR Convergence 2023

    Non-Linear Mendelian Randomization Analyses Support a Role for Low Vitamin D Status in Sarcopenia Risk

    Tingting Sha1, Yilun Wang2, Yuqing Zhang3, Nancy Lane4, Changjun Li5, Jie Wei6, Chao Zeng2 and Guanghua Lei2, 1Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China, 2Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, 3Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 4University of California, Hillsborough, CA, 5National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China, 6Health Management Center, Xiangya Hospital Central South University, Changsha, China

    Background/Purpose: Vitamin D deficiency is commonly associated with sarcopenia; however, the latest International Clinical Practice Guidelines for Sarcopenia do not recommend vitamin D supplementation for…
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