ACR Meeting Abstracts

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Abstracts tagged "Muscle Function"

  • Abstract Number: 0560 • ACR Convergence 2024

    Association Between a Self-Report Screening Tool for Sarcopenia (SARC-F) and Disease Activity, Muscle Strength and Muscle Power Measures, Patient-Reported Outcomes and Body Composition in Patients with Spondyloarthritides

    Iuliia Kononenko1, Marius Bedei2, Bjoern Buehring3, Xenofon Baraliakos4 and Uta Kiltz5, 1Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Bochum, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Herne, Germany, 3Bergisches Rheuma-Zentrum, Wuppertal, Germany, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany

    Background/Purpose: The SARC-F is a self-report screening tool for sarcopenia (Sar) used to identify individuals at risk for poor functional outcomes [1]. The aim of this study was…
  • Abstract Number: 0684 • ACR Convergence 2024

    The Diagnostic Accuracy of Ultrasound for Low Muscle Mass in Women with Systemic Sclerosis

    Lucas Dória1, Vanessa Hax2, André Mallmann2, Rafaela Santo3, Leonardo Santos2, Stephanie Pilotti2, Daniel Moraes2, Isabella Boening2, Pedro Glanze2, ODIRLEI MONTICIELO1, Ricardo Xavier4 and Rafael Chakr5, 1Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 2Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 3Health Research and Innovation Science Centre, Klaipeda University, Klaipeda, Lithuania, Porto Alegre, Rio Grande do Sul, Brazil, 4Universidade Federal do Rio Grande do Sul, Porto Alegre/RS, Rio Grande do Sul, Brazil, 5Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

    Background/Purpose: Patients with systemic sclerosis (SSc) often experience body composition changes, including low muscle mass (myopenia), associated with physical disability, hospitalization and death. Our purpose…
  • Abstract Number: 1079 • ACR Convergence 2024

    Early Recognition of Myositis: Time Correlation Between Transaminases and Inflammatory Myopathy in a Community-Based Rheumatology Practice

    Anjali nidhaan, Shannon Iriza, Abbie West, Michael martin and Gauri Pethe, prisma health, columbia, SC

    Background/Purpose: Recognizing muscle breakdown as a potential cause of elevated transaminases is crucial in the primary care setting to facilitate early referral to rheumatology for…
  • Abstract Number: 1182 • ACR Convergence 2024

    Assessing Male Pelvic Floor Contractions Using a Novel External Pressure Device and Ultrasound

    Benedetto Giardulli1, Mirko Job1, Filippo Recenti1, Gaia Leuzzi1, Alessandro Muda2, Ottavia Buccarella1 and Marco Testa1, 1University of Genova, Savona, Italy, 2Lavagna Hospital - Radiology Dept., Genova, Italy

    Background/Purpose: Men with rheumatic and musculoskeletal diseases (RMD) often experience sexual dysfunctions such as pelvic floor pain and erectile dysfunctions, which affect their sexual well-being.…
  • Abstract Number: 2061 • ACR Convergence 2024

    Associations Between Intramyocellular Lipid and Muscle Function in Patients with Osteoarthritis

    Rachel Gillcrist1, Marianna Olave2, Ryan Armbruster3 and Joshua Baker4, 1Corporal Michael J. Crescenz VA Medical Center, Philadelphia, 2Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, 3University of Pennsylvania, Philadelphia, 4Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Intramyocellular lipids (IMCL), stored within lipid droplets in skeletal muscle cells, serve as an important metabolic fuel source during exercise. Endurance athletes have demonstrated higher…
  • Abstract Number: 2670 • ACR Convergence 2024

    Sera from Patients with Idiopathic Inflammatory Myopathy Induces Muscle Weakness, Mitochondrial Dysfunction and Induction of Cytokines in Isolated Skeletal Muscle

    Cecilia Leijding1, Suchada Kaewin2, Kristofer Andreasson1, Tomas Schiffer1, Angeles Galindo-Feria3, Begum Horuluoglu1, Mattias Carlstrom1, Stefano Gastaldello1, Helene Alexanderson4, Ingrid Lundberg5 and Daniel Andersson6, 1Karolinska Institutet, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, 3Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 4Karolinska University Hospital, Stockholm, Sweden, 5Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, 6Karolinska Institutet, Solna, Sweden

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune inflammatory muscle disorders characterized by symmetrical skeletal muscle weakness and accelerated fatigue. Although signs…
  • Abstract Number: 1147 • ACR Convergence 2023

    Blood-Based Biomarkers of Inflammation and Tissue Remodeling Can Discriminate Between Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis and Are Associated with Hand Function

    Helena Port I Linares1, Birte Coppers2, Sara Bayat2, Godonou Elie-Tino2, Larissa Valor-Mendez2, David Simon2, Filippo Fagni2, Giulia Corte2, Anne-Christine Bay-Jensen3, Koray Tascilar2, Axel Hueber4, Verena Schoenau2, Michael Sticherling5, Simon Heinrich6, Daniela Bohr2, Georg Schett7, Arnd Kleyer8, Sigrid Leyendecker6, Signe Holm Nielsen3 and Anna-Maria Liphardt9, 1Nordic Bioscience A/S / University of Copenhagen, Copenhagen, Denmark, 2Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology / Deutsches Zentrum Immuntherapie, Erlangen, Germany, 3Nordic Bioscience, Herlev, Denmark, 4Division of Rheumatology, Klinikum Nürnberg, Paracelsus Medical University / Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Nürnberg, Germany, 5Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Dermatology, Erlangen, Germany, 6Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Institute of Applied Dynamics, Erlangen, Germany, 7Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 8University Hospital Erlangen, Erlangen, Germany, 9Friedrich-Alexander-University Erlangen-Nuremberg, Internal Medicine 3 - Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany

    Background/Purpose: Inflammatory musculoskeletal diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are characterized by physical function impairment due to progressive inflammatory and structural changes.…
  • Abstract Number: 1177 • ACR Convergence 2023

    Anti-HMGCR Autoantibody Levels in the Follow-up of Statin-induced Immune-mediated Necrotizing Myopathy: Multicentric Study of 24 Patients

    David Martinez-Lopez1, Cristina Corrales Selaya2, Diana Prieto-Peña2, Piotr Szczesny3, Antonella Notarnicola4, Marcos Lopez-Hoyos5, Ricardo Blanco6, Ingrid Lundberg7 and Maryam Dastmalchi7, 1Hospital de Sierrallana, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 4Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 5Marques de Valdecilla University Hospital-IDIVAL, Santander, Spain, 6Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 7Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden

    Background/Purpose: Statin-induced immune-mediated necrotizing myopathy (IMNM) is associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. It is characterized by elevated creatine kinase (CK) levels, and severe muscle…
  • Abstract Number: 1789 • ACR Convergence 2023

    Microtrauma Exacerbates Arthritis and Enthesitis in Curdlan-administered SKG Mice by Inducing FGF16 Expresssion

    Seung Hoon Lee1, Chanhyeok Jeon1, Sungsin Jo1 and Tae-Hwan Kim2, 1Hanyang University Institute for Rheumatology Research, Seoul, South Korea, 2Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose: Microtrauma might be considered a crucial of various environmental factors in AS, but there is still unknown whether microtrauma has a direct/indirect role in…
  • Abstract Number: 1957 • ACR Convergence 2023

    Non-Linear Mendelian Randomization Analyses Support a Role for Low Vitamin D Status in Sarcopenia Risk

    Tingting Sha1, Yilun Wang2, Yuqing Zhang3, Nancy Lane4, Changjun Li5, Jie Wei6, Chao Zeng2 and Guanghua Lei2, 1Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China, 2Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, 3Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 4University of California, Hillsborough, CA, 5National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China, 6Health Management Center, Xiangya Hospital Central South University, Changsha, China

    Background/Purpose: Vitamin D deficiency is commonly associated with sarcopenia; however, the latest International Clinical Practice Guidelines for Sarcopenia do not recommend vitamin D supplementation for…
  • Abstract Number: 1971 • ACR Convergence 2023

    Muscle Pathology in Patients with Primary Biliary Cholangitis

    Jose Cesar Milisenda1, Iago Pinal-Fernandez2, Katherine Pak2, Maria Casal-Dominguez3, Yaiza Duque-Jaimez4, Gloria Garrabou1, Sandra Muñoz-Braceras5, Mariona Guitart-Manpel1, Jose Jiram Torres-Ruiz5, Ester Tobias4, Maria Dolores Cano4, Iban Aldecoa4, Josep Maria Grau1 and Andrew Mammen3, 1Muscle Research Unit, Internal Medicine Service, Hospital Clinic, Barcelona, Spain, 2National Institutes of Health, Bethesda, MD, 3NIH, Bethesda, MD, 4Hospital Clínic de Barcelona, Barcelona, Spain, 5Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD

    Background/Purpose: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that primarily affects middle-aged women. It is characterized by elevated serum alkaline phosphatase levels,…
  • Abstract Number: 2467 • ACR Convergence 2023

    Quadriceps Muscle Fat Composition but Not Muscle Energetics Is Associated with Knee Osteoarthritis: Initial Results from the Study of Muscle, Mobility, and Aging

    Giovanna Distefano1, Daniel Evans2, Peggy Cawthon2, John Lynch2, Thomas Link2, Philip Kramer3, Stephanie Harrison2, Bret Goodpaster4, Jane Cauley5, Theresa Mau2, Paul Coen4, Lauren Sparks4 and Nancy Lane6, 1AventisHealth, Orlando, FL, 2University of California San Francisco, San Francisco, CA, 3Wake Forest, Winston-Salem, NC, 4Aventis Health, Orlando, FL, 5University of Pittsburgh, Pittsburgh, PA, 6University of California, Hillsborough, CA

    Background/Purpose: Osteoarthritis (OA) remains the most common cause of joint pain and disability with age, and to date, effective treatments to reduce pain and slow…
  • Abstract Number: 0302 • ACR Convergence 2023

    Remission in Anti-HMGCR Positive Immune-mediated Necrotizing Myopathy Without the Use of Glucocorticoids: A Multicentric Study of 24 Patients

    David Martinez-Lopez1, Cristina Corrales Selaya2, Diana Prieto-Peña2, Piotr Szczesny3, Antonella Notarnicola4, Ricardo Blanco5, Ingrid Lundberg6 and Maryam Dastmalchi6, 1Hospital de Sierrallana, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 4Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 6Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden

    Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies. This condition is characterized by progressive…
  • Abstract Number: 1233 • ACR Convergence 2022

    Ultrasound Is Reliable in the Assessment of Muscle Echogenicity in Patients with Rheumatic Diseases: Results of a Multicenter International Web-based Study

    Andrea Di Matteo1, Erica Moscioni2, Maria Giovanna Lommano1, Edoardo Cipolletta1, Gianluca Smerilli1, Sonia Farah1, Carla Airoldi3, Sibel Aydin4, Becciolini Andrea5, Karina Bonfiglioli6, Marina Carotti7, Greta Carrara8, Tomas Cazenave9, Davide Corradini10, Micaela Ana Cosatti11, Juan Josè de Agustin12, Giulia Maria Destro Castaniti13, Marco Di Carlo1, Eleonora Di Donato5, Luca Di geso14, Ashley Elliott15, Daniela Fodor16, Francesca Francioso1, Alessandra Gabba17, Cristina Hernández-Díaz18, Rudolf Horvath19, Jana Hurnakova19, Diogo Jesus20, Josefina Marin21, Maria Victoria Martire22, Riccardo Mashadi-Mirza23, Marco Massarotti24, Alice Andreea Musca25, Jagdish Nair26, Tadashi Okano27, Ioannis Papalopoulos28, Javier Eduardo Rosa21, Marcos Rosemffet29, João Rovisco30, Davide Rozza8, Fausto Salaffi1, Crescenzio Scioscia31, Carlo Alberto Scirè8, Maria-Magdalena Tamas32, Shun Tanimura33, Lucio Ventura-Rios18, Catalina Villota-Eraso34, Orlando Villota35, Paraksevi V Voulgari36, Florentin Ananu Vreju37, Gentiana Vukatana37, Johana Zacariaz Hereter21, Anna Zanetti8, Walter Grassi1 and Emilio Filippucci1, 1Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi, Italy, 2Polytechnic University of Marche, Jesi, Italy, 3Hospital Provincial, Rosario, Argentina, 4University of Ottawa, Rheumatology, Ottawa, Canada, Ottawa, ON, Canada, 5Department of Medicine, Internal Medicine and Rheumatology Unit, Azienda Ospedaliero Universitaria di Parma, Parma, Italy, 6Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Department of Radiology, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy, 8Epidemiology Unit, Italian Society of Rheumatology, Milano, Italy, 9Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 10Rheumatology Unit, University Clinic AOU Cagliari, Cagliari, Italy, 11CEMIC, Centro de educación médica e investigaciones médicas "Norberto Quirno", Buenos Aires, Argentina, 12Vall D'hebron University Hospital, Barcelona, Spain, 13Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Rheumatology section, University of Palermo, Palermo, Italy, 14Ospedale Madonna del Soccorso, Department of Internal Medicine, San Benedetto del Tronto, Italy, 15Centre for Experimental Medicine, Queen's University, Belfast, Northern Ireland, United Kingdom, 162nd Internal Medicine Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, 17Local Health Unit (ASL), Oristano, Italy, 18Division de Reumatologia. Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, 19Department of Paediatric and Adult Rheumatology, University Hospital Motol, Prague, Czech Republic, 20Rheumatology Department, Centro Hospitalar de Leiria, Leira, Portugal, 21Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 22San Roque Hospital, La Plata, Buenos Aires, Argentina, 23Radiology Department, A.O. Ospedali Riuniti Marche Nord, Pesaro, Italy, 24Department of Rheumatology, University Hospitals Dorset NHS Foundation Trust, Christchurch Hospital, Christchurch, United Kingdom, 25Department of Rheumatology - Colentina Clinical Hospital, Bucharest, Romania, 26Rheumatology, Liverpool University Hospitals Foundation Trust, Liverpool, United Kingdom, 27Department of Orthopedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan, 28Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Heraklion, Heraklion, Greece, 29Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 30Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 31Department of Emergency and Organ Transplantations-Rheumatology Unit, University of Bari "Aldo Moro", Bari, Italy, 32Department of Rheumatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, 33Rheumatology Department, Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan, 34IPS Servicio integral de reumatología e inmunología Dr Orlando Villota, Pasto, Colombia, 35Division of Rheumatology, Fundación Hospital San Pedro, Pasto, Colombia, 36Department of Rheumatology, School of Health Science, Faculty of Medicine, University of Ioannina, Ioannina, Greece, 37Rheumatology Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania, 37Rheumatology Unit; IRCCS Policlinico S. Orsola Malpighi, Bologna, Italy

    Background/Purpose: Studies have showed that an increased ultrasound (US) muscle echogenicity indicating fatty replacement/fibrosis of muscle tissue may represent an early indicator of muscle involvement associated…
  • Abstract Number: 1886 • ACR Convergence 2022

    Statin-induced Immune-mediated Miopathy: Treatment with Glucocorticoid-free Protocols and Role of Muscle Biopsy in the Follow-up

    David Martínez-López1, Piotr Szczęsny2, Inger Nennesmo3, Karina Gheorghe4, Antonella Notarnicola5, Helene Alexanderson6, Ingrid Lundberg7 and Maryam Dastmalchi8, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 3Department of Pathology, Karolinska University Hospital,Pathology, Karolinska University Hospital., Stockholm, Sweden, 4Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet. Rheumatology, Karolinska University Hospital Stockholm, Sweden. Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 5Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 6Karolinska Institutet, Stockholm, Sweden, 7Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, 8Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a recently identified autoimmune condition associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies, characterized by progressive muscle weakness leading…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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