Abstracts tagged "MRI"

Abstract Number: 1300 • 2016 ACR/ARHP Annual Meeting
MRI-Detected Inflammation Is Associated with Functional Disability in Early Arthritis – Results of a Cross-Sectional Study
Leonie E Burgers¹, Wouter P Nieuwenhuis¹, Hanna W van Steenbergen¹, Elize C Newsum¹, Tom WJ Huizinga¹, Monique Reijnierse², Saskia le Cessie³ and Annette HM van der Helm-van Mil¹, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Medical statistics and Epidemiology, Department of Medical Statistics and Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Magnetic resonance imaging (MRI) sensitively detects inflammation, but the clinical relevance of MRI-detected inflammation is undetermined in early arthritis. Therefore, this cross-sectional study investigated…
Abstract Number: 3210 • 2016 ACR/ARHP Annual Meeting
10+ Years’ Follow-up of a Danish 2-Year Treat-to-Target RCT in Patients with Early Rheumatoid Arthritis: Baseline Predictors of Functional and Radiographic Outcomes
Merete Lund Hetland¹, Kristian Stengaard-Pedersen², Peter Junker¹, Hanne Lindegaard¹, Torkell Ellingsen¹, Jan Pødenphant², Henrik Skjødt¹, Aage Vestergaard², Bo Jannik Ejbjerg¹, Søren Jacobsen¹, Niels Steen Krogh¹, Mikkel Ostergaard¹ and Kim Hørslev-Petersen², ¹Rigshospitalet (Glostrup and Blegdamsvej), Århus University Hospital, Odense University Hospital, Herlev/Gentofte Hospital, Slagelse Sygehus, Chr X hospital (University of South Denmark) and Zitelab Aps, DANBIO Registry and Departments of Rheumatology, Glostrup, Denmark, ²Rigshospitalet (Glostrup and Blegdamsvej), Århus University Hospital, Odense University Hospital, Herlev/Gentofte Hospital, Slagelse Sygehus, Chr X hospital (University of South Denmark) and Zitelab Aps, DANBIO Registry and Departments of Rheumatology, Copenhagen, Denmark
Background/Purpose: Few RCTs have investigated long-term (10+ years) outcomes of goal-directed synovitis suppression in early rheumatoid arthritis (RA). The CIMESTRA trial was a 2-year double-blinded…
Abstract Number: 675 • 2016 ACR/ARHP Annual Meeting
Association Between Structural Lesions in the Sacroiliac Joints and Spinal Inflammatory Lesions in Patients with Non-Radiographic Axial Spondyloarthritis
Maxime Dougados¹, Robert G Lambert², Stephanie Wichuk³, Jean-Claude Becker⁴, Jack F Bukowski⁵, Heather Jones⁶, Lisa Marshall⁶, Annette Szumski⁷ and Walter Maksymowych³, ¹Rheumatology, Paris Descartes University, Paris, France, ²Department of Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Becker Clinical Research Consulting, New York, NY, ⁵Clinical Affairs, Pfizer, Collegeville, PA, ⁶Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁷inVentiv Health, Princeton, NJ
Background/Purpose: The relevance of structural lesions in non-radiographic axial SpA (nr-axSpA) is unclear, particularly without signs of MRI inflammation. In a post hoc analysis we…
Abstract Number: 1301 • 2016 ACR/ARHP Annual Meeting
Analysis of Anatomical Sites Causing Dactylitis and Their Responsiveness to Change Under TNF-Therapy in Psoriatic Arthritis By High Resolution MRI
Dr. Philipp Sewerin, PD Dr. Stefan Vordenbäumen, Dr. Ruben Sengewein, Prof. Dr. Matthias Schneider and Prof. Dr. Benedikt Ostendorf, Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany
Background/Purpose: Results: The following sites were most commonly involved in dactylitis: collateral ligament enthesitis 11/12 (92%); extensor tendons enthesitis 5/12 (42%); flexor tenosynovitis 9/12 (75%),…
Abstract Number: 678 • 2016 ACR/ARHP Annual Meeting
Additional Information from CT or MRI Imaging Can Increase Rheumatologists’ Consensus on Grading Sacroiliitis By Radiography: Results of the Trimage Project
Nigil Haroon¹, Xenofon Baraliakos², Anne Grethe Jurik³, Gercek Can⁴, Ali Balcı⁵, Muhammet Cinar⁶, Ediz Dalkilic⁷, Salim Donmez⁸, Omer Nuri Pamuk⁹, Yavuz Pehlivan¹⁰, Salih Pay¹¹, Handan Yarkan¹², Gokce Kenar¹³ and Nurullah Akkoc¹³, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ³Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁴Department of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ⁵Radiology, Dokuz Eylul University, Izmir, Turkey, ⁶Division of Rheumatology, Gülhane Military Medical Academy, School of Medicine, Ankara, Turkey, ⁷Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, ⁸Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, ⁹Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, ¹⁰Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, ¹¹Rheumatology, Yüksek Ihtisas University, Special Koru Hospital, Ankara, Turkey, ¹²Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, ¹³Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
Background/Purpose: The diagnosis of ankylosing spondylitis (AS) is anchored on definitive changes of sacroiliits by radiography. This is relevant not only to clinical diagnosis, but…
Abstract Number: 1302 • 2016 ACR/ARHP Annual Meeting
Silent Progression in Patients with Rheumatoid Arthritis: Is DAS28 Remission an Insufficient Goal in RA? Results from the German Remission-PLUS Cohort
Dr. Philipp Sewerin¹, PD Dr. Stefan Vordenbäumen¹, Annika Hoyer², Ralph Brinks¹, Dr. Christian Buchbender³, Dr. Christoph Schleich⁴, Sabine Kamp¹, Prof. Dr. Gerald Antoch³, Prof. Dr. Matthias Schneider¹ and Prof. Dr. Benedikt Ostendorf¹, ¹Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany, ²Institute for Biometry and Epidemiology, German Diabetes Center, Duesseldorf, Germany, ³Diagnostic and Interventional Radiology, Heinrich-Heine-University, Düsseldorf, Germany, ⁴Dep. for diagnostic and interventional Radiology, Heinrich-Heine-University, Duesseldorf, Germany
Background/Purpose: disease activity score in 28 joints; Methods: Data-sets of 80 RA patients from the REMISSION-plus study cohort who fulfilled the following criteria were retrospectively…
Abstract Number: 688 • 2016 ACR/ARHP Annual Meeting
Spondyloarthritis Research Consortium of Canada (SPARCC) Baseline MRI SI Joint Score ≥2 Better Predicts Response to Golimumab Than Does Assessment of Spondyloarthritis International Society (ASAS) MRI Positivity in Nonradiographic Axial Spondyloarthritis
Walter Maksymowych¹, Anjela Tzontcheva², George Philip², Gina Bergman², Susan Huyck² and Sean P. Curtis², ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Merck & Co., Inc., Kenilworth, NJ
Background/Purpose: Golimumab (GLM) was shown to be effective for nonradiographic axial spondyloarthritis (nr-axSpA) in a randomized, double-blind, placebo-controlled, phase 3 study (GO-AHEAD; NCT01453725).1 The SPondyloArthritis…
Abstract Number: 1303 • 2016 ACR/ARHP Annual Meeting
Extended T2-Times in Cardiovascular Magnetic Resonance (CMR) in Patients with Systemic Lupus Erythematosus (SLE) and Persisted Dyspnoea: Is SLE-Associated Myocarditis an Underestimated Problem?
Dr. Philipp Sewerin¹, Vera Lachmann², Mareike Gastl², Patrick Behm³, PD Dr. Rebecca Fischer-Betz⁴, Prof. Dr. Benedikt Ostendorf¹, Dr. Gamal Chehab⁵, Prof. Dr. Matthias Schneider¹, Prof. Dr. Malte Kelm² and Dr. Florian Bönner², ¹Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, Düsseldorf, Germany, ²Department of Internal Medicine, Division of Cardiology, Pulmology and Vascular Medicine and Molecular Cardiology, Heinrich-Heine University, Düsseldorf, Germany, ³Heinrich-Heine University, Düsseldorf, Germany, ⁴Department of Rheumatology & Hiller Research Unit, Heinrich-Heine-University, Duesseldorf, Germany, ⁵Department of Rheumatology & Hiller Research Unit, Heinrich-Heine University, 40225 Duesseldorf, Germany
Background/Purpose: To investigate the value of cardiovascular magnetic resonance (CMR) and T2-mapping in patients with systemic lupus erythematosus (SLE) and persistent dyspnoea without sings for…
Abstract Number: 697 • 2016 ACR/ARHP Annual Meeting
Does Axial Spondyloarthritis Phenotype Correlate with Imaging Morphotype?
Xenofon Baraliakos¹, Annette Szumski², Heather Jones³ and Lianne S. Gensler⁴, ¹Rheumazentrum, Ruhr University, Bochum, Germany, ²inVentiv Health, Princeton, NJ, ³Inflammation & Immunology, Pfizer, Collegeville, PA, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Traditionally, radiographic imaging was used to describe morphological differences between various types of axial SpA (axSpA). MRI has advanced understanding of disease, enabled earlier…
Abstract Number: 1304 • 2016 ACR/ARHP Annual Meeting
2D and 3D Measurements of Osteoarthritis Joint Space Width Have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from the Osteoarthritis Initiative
Aaron Ray¹, Michael A Bowes², Bright Dube¹, Elizabeth M.A. Hensor¹, Andrew J Barr¹ and Philip G. Conaghan¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom
2D and 3D Measurements of Osteoarthritis Joint Space Width have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from…
Abstract Number: 716 • 2016 ACR/ARHP Annual Meeting
Radiographic Progression and Changes in Inflammation and Structural Damage on Serial MRI Examinations over 5 Years in Patients with Ankylosing Spondylitis Treated with TNF-Alpha Inhibitors
Susanne Juhl Pedersen¹, Ulrich Weber², Roula Said Nahal³, Inge Juul Sorensen¹, Anne Gitte Loft⁴, Niels Tvede¹, Gina Kollerup¹, Lars Juul¹, Gorm Thamsborg¹, Ole Rintek Madsen¹, Jakob M. Møller⁵, Lone Balding⁶, Anne Grethe Jurik⁷ and Mikkel Østergaard⁸, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ²Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, ³Ambroise Paré Hospital, Boulogne-Billancourt, France, ⁴Departments of Rheumatology at Vejle and Aarhus Hospitals, Vejle and Aarhus, Denmark, ⁵Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark, ⁶Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, ⁷Dept. of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁸Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark
Background/Purpose: Only few studies have investigated long-term radiographic progression in the spine of patients with ankylosing spondylitis (AS). Moreover, no studies have reported changes in…
Abstract Number: 1307 • 2016 ACR/ARHP Annual Meeting
Anatomical Patterns Suggest the Involvement of Biomechanical Stress in the Pathogenesis of Erosions in Rheumatoid Arthritis
Matthew A. Jessome¹, Michael A. Tomizza¹, Karen A. Beattie², William G. Bensen², Raja S. Bobba², Alfred Cividino², Patrick D. Emond², Chris Gordon², Lawrence Hart², Maggie Larche², Arthur Lau³, Ruben Tavares², Stephen Tytus² and Jonathan D. Adachi², ¹Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, ²St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ³50 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: There is limited data outlining the anatomic characteristics of bone erosions of the small joints in rheumatoid arthritis (RA). In particular, there is minimal…
Abstract Number: 893 • 2016 ACR/ARHP Annual Meeting
Preliminary Results of a Multi Modal Imaging Study Suggests a Better Accuracy for the Diagnosis of Giant Cell Arteritis
Augustin Lecler¹, Samuel Bidot², Frederique Charbonneau¹, Sabine Derrien², Herve Picard³ and Gaelle Clavel⁴, ¹Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France, ²Department of Ophthalmology, Fondation Ophtalmologique A. de Rothschild, Paris, France, ³Clinical Research Unit, Fondation Ophtalmologique A. de Rothschild, Paris, France, ⁴Department of Internal Medecine, Fondation Ophtalmologique A. de Rothschild, Paris, France
Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in patient over 50 years of age. It is a medical emergency as it…
Abstract Number: 1494 • 2016 ACR/ARHP Annual Meeting
Myocardial Structure, Function, and Fibrosis in Patients with Rheumatoid Arthritis and Matched Control Subjects
Michelle J. Ormseth¹, William Bradham², Comfort Elumogo³, Srikanth Palanisamy⁴, Chia Liu⁵, Mark Lawson², Jonathan Soslow², Nadine Kawel⁶, David A. Bluemke⁷ and C Michael Stein², ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Vanderbilt University Medical Center, Nashville, TN, ³National Institutes of Health, Bethesada, MD, ⁴Cornell University, Ithaca, NY, ⁵National Institutes of Health, Bethsada, MD, ⁶National Institutes of Health, Bethsada, TN, ⁷National Institutes of Health, Bethesda, MD
Background/Purpose: The prevalence of heart failure is increased 2-fold in RA; this is not explained by ischemic heart disease or other risk factors for heart…
Abstract Number: 907 • 2016 ACR/ARHP Annual Meeting
Rituximab in Patients with Takayasu Arteritis: A Single Center Experience on Five Patients
Giulia Pazzola¹, Francesco Muratore¹, Luigi Boiardi², Mariagazia Catanoso¹, Alessandra Soriano³, Pierluigi Macchioni¹, Lucia Spaggiari⁴, Massimiliano Casali⁵, Nicolò Pipitone¹, Niccolò Possemato⁶ and Carlo Salvarani¹, ¹Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ²Rheumatology Unit, Arcispedale S.Maria Nuova, IRCCS, Reggio Emilia, Italy, ³Rheumatology Unti, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁴Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁵Nuclear Medicine, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁶Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy
Background/Purpose: Takayasu arteritis (TAK) is a large vessel vasculitis involving the aorta and its major branches in patients younger than 40 years. Glucocorticoids (GCs) are…

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