ACR Meeting Abstracts

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Abstracts tagged "MRI"

  • Abstract Number: 594 • 2017 ACR/ARHP Annual Meeting

    Imaging Biomarkers in Crohn’s Associated Axial Spondyloarthritis

    Fardina Malik1, John A. Carrino2, Madeline Epsten3, Ellen Scherl4, Stephanie Wichuk5, Ulrich Weber6, Susanne J Pedersen7, Joel Paschke8, Jackie Szymonifka3, Georg Kroeber9, Randy Longman4, Walter P. Maksymowych5 and Lisa A. Mandl3, 1Rheumatology, Hospital For Special Surgery, New York, NY, 2Radiology, Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Gastroenterology, Weill Cornell Medical College, New York, NY, 5Medicine, University of Alberta, Edmonton, AB, Canada, 6Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, 7Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, 8CARE Arthritis, Edmonton, AB, Canada, 9University of Southern Denmark, Odense, Denmark

    Background/Purpose: Axial SpA has been reported in 4-16% of patients with Crohn's disease (CD). However, some plain radiograph or magnetic resonance imaging (MRI) studies in…
  • Abstract Number: 2406 • 2017 ACR/ARHP Annual Meeting

    Increased Cartilage Damage in Metacarpophalangeal Joints of ACPA Positive Rheumatoid Arthritis (RA) Patients Using T2 Mapping in 3 Tesla Magnetresonance Imaging (MRI)

    Nina Renner1, Arnd Kleyer2, David Simon2, Gerhard Krönke3, Juergen Rech2, Georg Schett2, Goetz Welsch4 and Milena L. Pachowsky1, 1Department of Trauma and Orthopedic Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany, 2Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany., Erlangen, Germany, 3Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany., Erlangen, Austria, 4UKE Athleticum, University Hospital Hamburg-Eppendorf, Hamburg, Germany

    Background/Purpose: T2 mapping is a non-invasive MRI approach to measure cartilage quality, reflecting cartilage hydration and collagen integrity without using contrast enhancement. It has been…
  • Abstract Number: 633 • 2017 ACR/ARHP Annual Meeting

    Improvement of Joint Inflammation As Assessed By MRI and Power Doppler Ultrasound (PDUS) in an Open Label Study in Patients with Active Psoriatic Arthritis Treated with Secukinumab.

    Eleni Kampylafka1, Isabelle Oliveira1, Christina Linz2, Veronika Lerchen1, Matthias Englbrecht1, Michael Sticherling3, Arnd Kleyer1, Juergen Rech1, Georg Schett1 and Axel J. Hueber1, 1Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, 2Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, e, Germany, 3Department of Dermatology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

    Background/Purpose: Secukinumab, an anti-interleukin 17A monoclonal antibody, showed significant improvement of signs and symptoms of psoriatic arthritis (PsA) in phase 3 studies. Available studies used…
  • Abstract Number: 2753 • 2017 ACR/ARHP Annual Meeting

    Brain Functional Connectivity Features of Pain Centralisation Relate to Degree of ‘Fibromyalgianess’ in Rheumatoid Arthritis

    Neil Basu1, Chelsea Cummiford2, Eric Ichesco2, Tony Larkin2, Richard E. Harris2, Alison Murray3, Gordon Waiter4 and Daniel J. Clauw5, 1Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom, 2Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 3Aberdeen Brain Imaging Center, University of Aberdeen, Aberdeen, United Kingdom, 4Aberdeen Brain Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, 5Anesthesiology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Many rheumatoid arthritis (RA) patients continue to report pain despite excellent control of inflammation with immunotherapy regimes. Variable degrees of co-existing fibromyalgia (FM) may…
  • Abstract Number: 720 • 2017 ACR/ARHP Annual Meeting

    Ambulatory Blood Pressure and Skin Sodium Concentrations in Patients with Systemic Lupus Erythematosus

    Daniel Carranza Leon1, Cecilia P. Chung1, Michelle J. Ormseth2, Annette M. Oeser3, Ping Wang4, Adriana Marton1, Jens Titze3 and C. Michael Stein1, 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Rheumatology, Vanderbilt Medical Center, Nashville, TN, 3Vanderbilt University Medical Center, Nashville, TN, 4Radiology, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Ambulatory 24-hour blood pressure and nocturnal blood pressure measurements are better predictors of cardiovascular risk than office blood pressure. Patients with systemic lupus erythematosus…
  • Abstract Number: 2806 • 2017 ACR/ARHP Annual Meeting

    Integrated Longitudinal Analysis Increases Precision and Reduces Bias: A Comparative 5-Year Analysis in the DESIR Cohort

    Alexandre Sepriano1, Sofia Ramiro2, Désirée van der Heijde1, Maxime Dougados3, Pascal Claudepierre4, Antoine Feydy5, M. Reijnierse6, Damien Loeuille7 and Robert B.M. Landewé8, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 3Paris-Descartes University,, Paris, France, 4Hôpital Henri Mondor, Créteil, France, 5Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, 6Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 8University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands

    Background/Purpose: Evaluation of imaging is important in spondyloarthritis (SpA) research, but loss to follow up often jeopardizes interpretation of the evaluation. The Interpretation may further…
  • Abstract Number: 741 • 2017 ACR/ARHP Annual Meeting

    Cardiac MRI in Systemic Sclerosis As Prognostic Tool of Cardiac Mortality in Symptomatic Patients

    Silvia Bosello1, Giovanni Canestrari1, Enrico De Lorenzis1, Gerlando Natalello2, Federico Parisi1, Agostino Meduri3, Riccardo Marano3, Gianfranco Ferraccioli4 and Elisa Gremese5, 1Division of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, 2Division of Rhematology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, 3Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, 4Institute of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, 5Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy

    Background/Purpose: Cardiac involvement is a relevant prognostic determinant of outcome in Systemic Sclerosis (SSc). Since the role of cardiac MRI (CMR) is still uncertain, we…
  • Abstract Number: 2912 • 2017 ACR/ARHP Annual Meeting

    The Neural Correlates of Inflammation in RA: A Multi-Modal MRI Study

    Andrew Schrepf1, Chelsea Cummiford1, Eric Ichesco1, Tony Larkin1, Steven E. Harte1, Richard E. Harris1, Alison Murray2, Gordon Waiter3, Daniel J. Clauw4 and Neil Basu5, 1Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 2Aberdeen Brain Imaging Center, University of Aberdeen, Aberdeen, United Kingdom, 3Aberdeen Brain Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, 4Chronic Pain & Fatigue Research Center, University of Michigan, Ann Arbor, MI, 5Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom

    Background/Purpose: Inflammation is the hallmark of disease activity in rheumatoid arthritis (RA). RA is characterized by fatigue and cognitive/affective disturbances, and these symptoms often worsen…
  • Abstract Number: 872 • 2017 ACR/ARHP Annual Meeting

    Myocardial Abnormalities Improve in RA Patients Treated Actively – a Cardiac MRI Follow-up Study

    Riitta Koivuniemi1,2, Mia Holmström3, Antti Kuuliala2, Sari Kivistö3 and Marjatta Leirisalo-Repo1,2, 1Rheumatology, University of Helsinki, Helsinki, Finland, 2Rheumatology, Helsinki University Hospital, Helsinki, Finland, 3Radiology, HUS Medical Imaging Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

    Background/Purpose: Patients with RA are prone to develop myocardial dysfunction, in which chronic inflammation is suggested to play an important role. We have previously shown…
  • Abstract Number: 2947 • 2017 ACR/ARHP Annual Meeting

    Do Bone Marrow Lesions Reactivate Endochondral Ossification Leading to Osteophyte Genesis? Data from the Osteoarthritis Initiative

    Leticia Deveza1, Laurence Teoh2, Elena Ochoa-Albiztegui3, Ali Guermazi4, Frank Roemer4,5 and David Hunter1, 1Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 2Department of General Medicine, Middlemore Hospital, Auckland, New Zealand, Auckland, New Zealand, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, New York, NY, 4Department of Radiology, Boston University School of Medicine, Boston, MA, USA, Boston, MA, 5Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: Osteophytes are formed through reactivation of endochondral ossification. In adults, reactivation of endochondral ossification may occur in the context of fracture repair. As yet,…
  • Abstract Number: 1386 • 2017 ACR/ARHP Annual Meeting

    Tenosynovitis in the Forefoot at Disease Presentation Is Specific for RA: Results from a Cross-Sectional MRI Study in Early Arthritis

    Yousra J. Dakkak1, Debbie M. Boeters2, Annette H.M. van der Helm-van Mil2 and M. Reijnierse3, 1Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The foot is a preferential location for rheumatoid arthritis (RA)-manifestation, but physical examination of the metatarsophalangeal (MTP) joints is difficult. Magnetic Resonance Imaging (MRI)…
  • Abstract Number: 2964 • 2017 ACR/ARHP Annual Meeting

    Structural Damage in Patients with Very Early RA Is Predicted with Clinical Measures of Baseline Disease Activity: DAS28 (CRP), SDAI, M-DAS28 and RAPID3 but Not CDAI

    Edward C. Keystone1, H Ahmad2, Yusuf Yazici3, X Liu2 and MJ Bergman4, 1University of Toronto, Toronto, ON, Canada, 2Bristol-Myers Squibb, Princeton, NJ, 3New York University School of Medicine, New York, NY, 4Drexel University College of Medicine, Philadelphia, PA

    Background/Purpose: Clinicians rely on time-efficient, validated disease activity assessments to help accurately predict disease progression in patients with RA. The utility of the Routine Assessment…
  • Abstract Number: 1504 • 2017 ACR/ARHP Annual Meeting

    More Than 10 Percent Patients with Recent Onset Chronic Mechanical Back Pain Fulfill the Modified NY Criteria for Sacroiliitis

    Anna Molto1, Laure Gossec2, Violaine Foltz2, Romain Beaufort3, Jean Denis Laredo4, Pascal Richette5, Philippe Dieude6, Philippe Goupille7, Antoine Feydy8 and Maxime Dougados9, 1Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, 2UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, 3Private Practice,, Paris, France, 4Radiology Department, Lariboisière Hospital, Paris, France, 5Rheumatology Department, Université Paris Diderot, Paris, France, 6Université Paris-Diderot, Paris, France, 7Department of Rheumatology, CHRU de Tours; and Université François-Rabelais de Tours, Tours, France, 8Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, 9Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France

    Background/Purpose: only scarce data are available regarding the diagnostic value of pelvic Xrays abnormalities suggestive of axial spondyloarthritis (axSpA) in patients with recent onset back…
  • Abstract Number: 235 • 2017 ACR/ARHP Annual Meeting

    MRI in Rheumatoid Arthritis: Does Quantifying the Number of Erosive Lesions Improve Detection of Subtle Erosive Progression Compared to the Omeract RA MRI Scoring System?

    Ulf Sundin1, Anna-Birgitte Aga2, Tore K Kvien3, Siri Lillegraven4 and Espen A. Haavardsholm4, 1*Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Diakonhjemmet Hospital, Oslo, Norway, 4Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Early detection of erosive progression is an important application of MRI in RA. For research purposes the OMERACT Rheumatoid Arthritis MRI Scoring system (RAMRIS)…
  • Abstract Number: 1831 • 2017 ACR/ARHP Annual Meeting

    A Positive MRI of the Sacroiliac Joints Is Not Specific for Axial Spondyloarthritis but Frequently Occurs in Healthy Individuals

    Janneke de Winter1, Manouk de Hooge2, Marleen van de Sande1, Lonneke van Hoeven3, Jet de Jong1, Anoek de Koning2, Inger Jorid Berg4, Roberta Ramonda5, Dominique Baeten1,6, Désirée van der Heijde7, Angelique Weel8 and Robert B.M. Landewé9, 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, 6UCB Pharma, Slough, United Kingdom, 7Leiden University Medical Center, Leiden, Netherlands, 8Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 9Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands

    Background/Purpose: Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%) but the specificity is not well known, hence we compared…
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