Abstracts tagged "MRI"

Abstract Number: 864 • 2018 ACR/ARHP Annual Meeting
The Diagnostic Utility of the Relation between MRI Bone Marrow Edema and Other Types of MRI Lesions in the Sacroiliac Joints in Axial Spondyloarthritis
Sengül Seven¹, Pernille Hededal², Mikkel Østergaard³, Lone Morsel-Carlsen⁴, Inge Juul Sørensen⁵, Birthe Bonde⁶, Gorm Thamborg⁷, Oliver Hendricks⁸, Niklas Rye Jørgensen⁹ and Susanne J Pedersen¹⁰, ¹Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup., 2600 Glostrup, Denmark, ²Dept. of Radiology, Rigshospitalet, University of Copenhagen, Glostrup., Glostrup, Denmark, ³Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup., Glostrup, Denmark, ⁴Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ⁵Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark, ⁶Birthe Bonde Clinic of Physiotherapy, Copenhagen, Denmark, ⁷Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark, ⁸King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ⁹Dept. of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark, ¹⁰Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark
Background/Purpose: MRI detected bone marrow edema (BME) plays a central role in the ASAS (Assessment of Spondyloarthritis International Society) classification criteria for axial spondyloarthritis (axSpA).…
Abstract Number: 2286 • 2018 ACR/ARHP Annual Meeting
Myositis and Fasciitis By Magnetic Resonance Imaging in Recent-Onset Polymyalgia Rheumatica and Effect of Tocilizumab Therapy
Jean Patrick Laporte¹, Florent Garrigues², Anais Huwart², Sandrine Jousse-Joulin³, Thierry Marhadour¹, Dewi Guellec³, Divi Cornec⁴, Valérie Devauchelle-Pensec³ and Alain Saraux³, ¹CHU Brest, Brest, France, ²Radiology, CHU Brest, Brest, France, ³Rheumatology, CHU Brest, Brest, France, ⁴Rheumatology and UMR1227, Lymphocytes B et Autoimmunité, CHU Brest, Brest, France
Background/Purpose: To assess the prevalence of myofascial inflammatory lesions visible by magnetic resonance imaging (MRI) and their changes after tocilizumab therapy in active polymyalgia rheumatica…
Abstract Number: 14L • 2017 ACR/ARHP Annual Meeting
Miv-711, a Novel Cathepsin K Inhibitor Demonstrates Evidence of Osteoarthritis Structure Modification: Results from a 6 Month Randomized Double-Blind Placebo-Controlled Phase IIA Trial
Philip G. Conaghan¹, Michael A Bowes², Sarah R. Kingsbury¹, Alan Brett², Gwenael Guillard², Åsa Jansson³, Cecilia Wadell³, Richard Bethell³ and John Öhd³, ¹University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³Medivir AB, Huddinge, Sweden

Background/Purpose: The need for drugs that achieve structure modification in OA is imminent but their development has been burdened by the need for large, long…
Abstract Number: 591 • 2017 ACR/ARHP Annual Meeting
Inflammation on MRI of Spine and Sacroiliac Joints Is Highly Predictive of Structural Damage in Axial Spondyloarthritis: The 5 Years Data of the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Robert B.M. Landewé³, Maxime Dougados⁴ and Désirée van der Heijde¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, ⁴Paris-Descartes University,, Paris, France
Background/Purpose: The effect of local inflammation on structural damage in patients (pts) with axial spondyloarthritis is not well known. We aimed to test the possible…
Abstract Number: 2208 • 2017 ACR/ARHP Annual Meeting
A Novel Omeract MRI Scoring System Providing Insights in the Association of MRI Synovitis and Bone Marrow Lesions with Pain in Thumb Base Osteoarthritis
F.P.B. Kroon¹, S. van Beest¹, W. Damman¹, R. Liu¹, J.L. Bloem², M. Reijnierse² and M. Kloppenburg^1,3, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Osteoarthritis (OA) in the thumb base joints (first carpometacarpal [CMC1] and scaphotrapeziotrapezoid [STT]) is highly prevalent and disabling, however much is still unknown about…
Abstract Number: 592 • 2017 ACR/ARHP Annual Meeting
Which Imaging Outcomes for AxSpA Are Most Sensitive to Change? a 5-Year Analysis of the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Désirée van der Heijde¹, Maxime Dougados³, Pascal Claudepierre⁴, Antoine Feydy⁵, M. Reijnierse⁶, Damien Loeuille⁷ and Robert B.M. Landewé⁸, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³Paris-Descartes University,, Paris, France, ⁴Hôpital Henri Mondor, Créteil, France, ⁵Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ⁸University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Several imaging outcomes have become available to assess inflammation and structural damage over time in patients with axial spondyloarthris (axSpA). However, no formal comparison…
Abstract Number: 2368 • 2017 ACR/ARHP Annual Meeting
Global Circumferential Strain By Assessed a Feature Tracking Cardiac Magnetic Resonance (CMR) Imaging Was Associated with Myocardial Fibrosis in RA Patients
Yasuyuki Kobayashi¹, Hitomi Kobayashi², Isamu Yokoe³, Atsuma Nishiwaki⁴, Akiyuki Kotoku⁵ and Masami Takei⁴, ¹Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ²Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁵Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Individuals with RA have a 1.5-2.0 fold higher risk of developing congestive heart failure (CHF) than the general population. It is important to understand…
Abstract Number: 594 • 2017 ACR/ARHP Annual Meeting
Imaging Biomarkers in Crohn’s Associated Axial Spondyloarthritis
Fardina Malik¹, John A. Carrino², Madeline Epsten³, Ellen Scherl⁴, Stephanie Wichuk⁵, Ulrich Weber⁶, Susanne J Pedersen⁷, Joel Paschke⁸, Jackie Szymonifka³, Georg Kroeber⁹, Randy Longman⁴, Walter P. Maksymowych⁵ and Lisa A. Mandl³, ¹Rheumatology, Hospital For Special Surgery, New York, NY, ²Radiology, Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Gastroenterology, Weill Cornell Medical College, New York, NY, ⁵Medicine, University of Alberta, Edmonton, AB, Canada, ⁶Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, ⁷Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, ⁸CARE Arthritis, Edmonton, AB, Canada, ⁹University of Southern Denmark, Odense, Denmark
Background/Purpose: Axial SpA has been reported in 4-16% of patients with Crohn's disease (CD). However, some plain radiograph or magnetic resonance imaging (MRI) studies in…
Abstract Number: 2406 • 2017 ACR/ARHP Annual Meeting
Increased Cartilage Damage in Metacarpophalangeal Joints of ACPA Positive Rheumatoid Arthritis (RA) Patients Using T2 Mapping in 3 Tesla Magnetresonance Imaging (MRI)
Nina Renner¹, Arnd Kleyer², David Simon², Gerhard Krönke³, Juergen Rech², Georg Schett², Goetz Welsch⁴ and Milena L. Pachowsky¹, ¹Department of Trauma and Orthopedic Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany, ²Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany., Erlangen, Germany, ³Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany., Erlangen, Austria, ⁴UKE Athleticum, University Hospital Hamburg-Eppendorf, Hamburg, Germany
Background/Purpose: T2 mapping is a non-invasive MRI approach to measure cartilage quality, reflecting cartilage hydration and collagen integrity without using contrast enhancement. It has been…
Abstract Number: 633 • 2017 ACR/ARHP Annual Meeting
Improvement of Joint Inflammation As Assessed By MRI and Power Doppler Ultrasound (PDUS) in an Open Label Study in Patients with Active Psoriatic Arthritis Treated with Secukinumab.
Eleni Kampylafka¹, Isabelle Oliveira¹, Christina Linz², Veronika Lerchen¹, Matthias Englbrecht¹, Michael Sticherling³, Arnd Kleyer¹, Juergen Rech¹, Georg Schett¹ and Axel J. Hueber¹, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ²Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, e, Germany, ³Department of Dermatology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany
Background/Purpose: Secukinumab, an anti-interleukin 17A monoclonal antibody, showed significant improvement of signs and symptoms of psoriatic arthritis (PsA) in phase 3 studies. Available studies used…
Abstract Number: 2753 • 2017 ACR/ARHP Annual Meeting
Brain Functional Connectivity Features of Pain Centralisation Relate to Degree of ‘Fibromyalgianess’ in Rheumatoid Arthritis
Neil Basu¹, Chelsea Cummiford², Eric Ichesco², Tony Larkin², Richard E. Harris², Alison Murray³, Gordon Waiter⁴ and Daniel J. Clauw⁵, ¹Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom, ²Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ³Aberdeen Brain Imaging Center, University of Aberdeen, Aberdeen, United Kingdom, ⁴Aberdeen Brain Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ⁵Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Many rheumatoid arthritis (RA) patients continue to report pain despite excellent control of inflammation with immunotherapy regimes. Variable degrees of co-existing fibromyalgia (FM) may…
Abstract Number: 720 • 2017 ACR/ARHP Annual Meeting
Ambulatory Blood Pressure and Skin Sodium Concentrations in Patients with Systemic Lupus Erythematosus
Daniel Carranza Leon¹, Cecilia P. Chung¹, Michelle J. Ormseth², Annette M. Oeser³, Ping Wang⁴, Adriana Marton¹, Jens Titze³ and C. Michael Stein¹, ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Rheumatology, Vanderbilt Medical Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Radiology, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Ambulatory 24-hour blood pressure and nocturnal blood pressure measurements are better predictors of cardiovascular risk than office blood pressure. Patients with systemic lupus erythematosus…
Abstract Number: 2806 • 2017 ACR/ARHP Annual Meeting
Integrated Longitudinal Analysis Increases Precision and Reduces Bias: A Comparative 5-Year Analysis in the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Désirée van der Heijde¹, Maxime Dougados³, Pascal Claudepierre⁴, Antoine Feydy⁵, M. Reijnierse⁶, Damien Loeuille⁷ and Robert B.M. Landewé⁸, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³Paris-Descartes University,, Paris, France, ⁴Hôpital Henri Mondor, Créteil, France, ⁵Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ⁸University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Evaluation of imaging is important in spondyloarthritis (SpA) research, but loss to follow up often jeopardizes interpretation of the evaluation. The Interpretation may further…
Abstract Number: 741 • 2017 ACR/ARHP Annual Meeting
Cardiac MRI in Systemic Sclerosis As Prognostic Tool of Cardiac Mortality in Symptomatic Patients
Silvia Bosello¹, Giovanni Canestrari¹, Enrico De Lorenzis¹, Gerlando Natalello², Federico Parisi¹, Agostino Meduri³, Riccardo Marano³, Gianfranco Ferraccioli⁴ and Elisa Gremese⁵, ¹Division of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ²Division of Rhematology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ³Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ⁴Institute of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ⁵Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy
Background/Purpose: Cardiac involvement is a relevant prognostic determinant of outcome in Systemic Sclerosis (SSc). Since the role of cardiac MRI (CMR) is still uncertain, we…
Abstract Number: 2912 • 2017 ACR/ARHP Annual Meeting
The Neural Correlates of Inflammation in RA: A Multi-Modal MRI Study
Andrew Schrepf¹, Chelsea Cummiford¹, Eric Ichesco¹, Tony Larkin¹, Steven E. Harte¹, Richard E. Harris¹, Alison Murray², Gordon Waiter³, Daniel J. Clauw⁴ and Neil Basu⁵, ¹Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Aberdeen Brain Imaging Center, University of Aberdeen, Aberdeen, United Kingdom, ³Aberdeen Brain Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ⁴Chronic Pain & Fatigue Research Center, University of Michigan, Ann Arbor, MI, ⁵Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom
Background/Purpose: Inflammation is the hallmark of disease activity in rheumatoid arthritis (RA). RA is characterized by fatigue and cognitive/affective disturbances, and these symptoms often worsen…

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