Abstracts tagged "MRI"

Abstract Number: 653 • 2018 ACR/ARHP Annual Meeting
Validation of Assessments in Spondyloarthritis International Society MRI Lesion Definitions in Axial Spondyloarthritis: Data from the Echography in Spondyloarthritis Cohort
Walter P. Maksymowych^1,2, Damien Loeuille³, Stephanie Wichuk⁴, Joel Paschke⁵, Olivia Judet⁶, Maxime Breban³, Maria-Antonietta D'Agostino⁷ and Robert G. Lambert⁸, ¹University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Ambroise Paré Hospital, Boulogne-Billancourt, France, ⁴Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁵CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, ⁶CHRU Vandoeuvre les Nancy, Vandœuvre-lès-Nancy, France, ⁷CHRU Vandoeuvre les Nancy, Vandoeuvre les Nancy, France, ⁸Radiology, Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The diversity of MRI lesions in the sacroiliac joints of patients with axial spondyloarthritis (axSpA) has only recently been appreciated and consistent terminology, descriptions,…
Abstract Number: 1347 • 2018 ACR/ARHP Annual Meeting
A Semi-Quantitative Whole Body Magnetic Resonance Imaging Assessment Tool to Define Musculoskeletal Abnormalities in Patients with Idiopathic Inflammatory Myopathies
Sara Faghihi-Kashani¹, Lisa G. Rider², David Bluemke³, Ashkan Malayeri⁴, Evrim Turkbey⁴, Joseph Shrader⁵, John McGrath⁶, Elizabeth Jones⁷, Jamie Marco⁸, Frederick W. Miller⁹ and Adam Schiffenbauer¹⁰, ¹Environmental Autoimmunity Group, National Institute of Environmental Health, Bethesda, MD, ²Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, ³Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁴Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁵Rehabilitation Medicine, National Institutes of Health, Bethesda, MD, ⁶Social and Scientific Systems, Inc., Durham, NC, ⁷Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, ⁸Radiology and Imaging Sciences National Institutes of Health, Bethesda, MD, ⁹Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, ¹⁰NIEHS, NIH, Bethesda, MD
Background/Purpose: There is a lack of standardized methodology for assessing whole body MRI (WBMRI) in idiopathic inflammatory myopathy (IIM) patients. This leads to difficulty in…
Abstract Number: 14L • 2017 ACR/ARHP Annual Meeting
Miv-711, a Novel Cathepsin K Inhibitor Demonstrates Evidence of Osteoarthritis Structure Modification: Results from a 6 Month Randomized Double-Blind Placebo-Controlled Phase IIA Trial
Philip G. Conaghan¹, Michael A Bowes², Sarah R. Kingsbury¹, Alan Brett², Gwenael Guillard², Åsa Jansson³, Cecilia Wadell³, Richard Bethell³ and John Öhd³, ¹University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³Medivir AB, Huddinge, Sweden

Background/Purpose: The need for drugs that achieve structure modification in OA is imminent but their development has been burdened by the need for large, long…
Abstract Number: 1504 • 2017 ACR/ARHP Annual Meeting
More Than 10 Percent Patients with Recent Onset Chronic Mechanical Back Pain Fulfill the Modified NY Criteria for Sacroiliitis
Anna Molto¹, Laure Gossec², Violaine Foltz², Romain Beaufort³, Jean Denis Laredo⁴, Pascal Richette⁵, Philippe Dieude⁶, Philippe Goupille⁷, Antoine Feydy⁸ and Maxime Dougados⁹, ¹Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³Private Practice,, Paris, France, ⁴Radiology Department, Lariboisière Hospital, Paris, France, ⁵Rheumatology Department, Université Paris Diderot, Paris, France, ⁶Université Paris-Diderot, Paris, France, ⁷Department of Rheumatology, CHRU de Tours; and Université François-Rabelais de Tours, Tours, France, ⁸Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁹Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: only scarce data are available regarding the diagnostic value of pelvic Xrays abnormalities suggestive of axial spondyloarthritis (axSpA) in patients with recent onset back…
Abstract Number: 235 • 2017 ACR/ARHP Annual Meeting
MRI in Rheumatoid Arthritis: Does Quantifying the Number of Erosive Lesions Improve Detection of Subtle Erosive Progression Compared to the Omeract RA MRI Scoring System?
Ulf Sundin¹, Anna-Birgitte Aga², Tore K Kvien³, Siri Lillegraven⁴ and Espen A. Haavardsholm⁴, ¹*Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Early detection of erosive progression is an important application of MRI in RA. For research purposes the OMERACT Rheumatoid Arthritis MRI Scoring system (RAMRIS)…
Abstract Number: 1831 • 2017 ACR/ARHP Annual Meeting
A Positive MRI of the Sacroiliac Joints Is Not Specific for Axial Spondyloarthritis but Frequently Occurs in Healthy Individuals
Janneke de Winter¹, Manouk de Hooge², Marleen van de Sande¹, Lonneke van Hoeven³, Jet de Jong¹, Anoek de Koning², Inger Jorid Berg⁴, Roberta Ramonda⁵, Dominique Baeten^1,6, Désirée van der Heijde⁷, Angelique Weel⁸ and Robert B.M. Landewé⁹, ¹Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁴Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, ⁶UCB Pharma, Slough, United Kingdom, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁹Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands
Background/Purpose: Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%) but the specificity is not well known, hence we compared…
Abstract Number: 307 • 2017 ACR/ARHP Annual Meeting
Biochemical Intervertebral Disc Alterations in Patients with Low Back Pain and Radiculopathy
Philipp Sewerin¹, Christoph Schleich², Ruben Sengewein³, Matthias Schneider⁴ and Benedikt Ostendorf¹, ¹Department and Hiller-Research-Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ²Dep. for diagnostic and interventional Radiology, Heinrich-Heine University, Duesseldorf, Germany, ³Department and Hiller Research Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ⁴Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
Background/Purpose: To assess the glycosaminoglycan (GAG) content of lumbar intervertebral discs (IVD) in patients with low back pain (LBP) and radiculopathy using glycosaminoglycan chemical exchange…
Abstract Number: 1845 • 2017 ACR/ARHP Annual Meeting
Comparison of Magnetic Resonance Angiography (MRA) and 18f-Fluorodeoxyglucose Positron Emission Tomography (PET) in Large Vessel Vasculitis
Kaitlin A. Quinn^1,2, Ashkan Malayeri³, Mark Ahlman³, Armin Bagheri⁴, Robert Evers⁵, Ali Cahid Civelek³, Elaine Novakovich⁶ and Peter C. Grayson⁷, ¹Rheumatology, MedStar Georgetown University Hospital, Washington, DC, ²NIAMS/NIH, Bethesda, MD, ³Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁴Vasculitis Translational Research Program, NIAMS, NIH, Bethesda, MD, ⁵NIH, Bethesda, MD, ⁶Systemic Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD, ⁷National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD
Background/Purpose: Magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose positron emission tomography (PET) may provide unique or redundant information in large vessel vasculitis (LVV). The study objective…
Abstract Number: 372 • 2017 ACR/ARHP Annual Meeting
Phenotype of Chronic Recurrent Multifocal Osteomyelitis in a Tertiary Referral Centre: The Great Ormond Street Hospital Experience
Kulsoom Riaz¹ and Sandrine Lacassagne², ¹Paediatric Rheumatology/Gastroenterology, Great Ormond Street Hospital, London, United Kingdom, ²Paediatric Rheumatology, Great Ormond Street Hospital, London, United Kingdom
Background/Purpose: Recurrent Multifocal Osteomyelitis (CRMO) is an aseptic inflammatory bone disease that typically affects the metaphases of the long bones. It affects children, adolescents and…
Abstract Number: 1877 • 2017 ACR/ARHP Annual Meeting
The Performance of MRI Using the 3D Volumetric Interpolated Breath-Hold Sequence (VIBE) Technique to Detect Structural Changes in Patients with Early Axial Spondyloarthritis in Comparison to Conventional Radiography and Computed Tomography
Xenofon Baraliakos¹, Florian Hoffmann¹, Xiaohu Deng², Yanyan Wang³, Feng Huang⁴ and Jürgen Braun⁵, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Chinese PLA General Hospital, Chinese PLA General Hospital, Beijing, China, ³Rheumatology, Chinese PLA General Hospital, Beijing, China, ⁴Chinese PLA General Hospital, Beijing, China, ⁵Institut für angewandte Statistik Dr. Jörg Schnitker GmbH, Bielefeld, Germany
Background/Purpose: Magnetic resonance imaging (MRI) is the gold standard for detection of inflammation in the sacroiliac joints (SIJ) of patients (pts) with axial spondyloarthritis (axSpA),…
Abstract Number: 586 • 2017 ACR/ARHP Annual Meeting
Validation of Online Calibration Modules for the Spondyloarthritis Research Consortium of Canada MRI Scores Based on Real-Time Experiential Learning
Matthew Maksymowych¹, Hanne Boutrup², Jonathan Cheah³, Riccardo Guglielmi⁴, Eric Heffernan⁵, Jacob Jaremko¹, Mats-Peter Johansson⁶, Simon Krabbe⁷, Georg Kroeber⁸, Fardina Malik⁹, Susanne Juhl Pedersen⁷, Sander Shafer⁶, Ulrich Weber¹⁰, Pam Weiss¹¹, Brian Trinh¹², Joel Paschke¹³ and Robert G. Lambert¹⁴, ¹Radiology, University of Alberta, Edmonton, AB, Canada, ²University of Copenhagen, Copenhagen, Denmark, ³Medicine, Hospital for Special Surgery, New York, NY, ⁴Radiology, Ente Ospedaliero Cantonale, Lugano, Switzerland, ⁵Radiology, St. Vincent's University Hospital, Dublin, Ireland, ⁶Rheumatology, Gentofte Hospital, Copenhagen, Denmark, ⁷Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, ⁸University of Southern Denmark, Odense, Denmark, ⁹Medicine- Rheumatology, Weill Cornell Medical College, New York, NY, ¹⁰Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, ¹¹Pediatrics, Children's Hospital Philadelphia, Philadelphia, PA, ¹²CARE Arthritis, EDMONTON, AB, Canada, ¹³CARE Arthritis, Edmonton, AB, Canada, ¹⁴University of Alberta, Edmonton, AB, Canada
Background/Purpose: The appropriate use of imaging-based scoring instruments is usually an ad hoc process based on passive learning from published manuscripts. Moreover, most instruments lack…
Abstract Number: 1996 • 2017 ACR/ARHP Annual Meeting
Changes in Cartilage Matrix Measured By MR T1ρ Are Correlated with Changes in Bone Erosion Volume Measured By HR-pQCT Three Months after MTX and Anti-TNF Treatment in Patients with Rheumatoid Arthritis: A Multi-Modality Imaging Study
Tomohiro Shimizu^1,2,3, Kenji Mamoto¹, Ursula Heilmeier¹, Matthew Tanaka¹, Andrew J Burghardt¹, Thomas Link¹, Jonathan Graf⁴, John B. Imboden Jr.⁵ and Xiaojuan Li⁶, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, ³Department of Orthopaedic Surgery, Hokkaido University, Sapporo, Japan, ⁴Department of Medicine, Division of Rheumatology Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, ⁵Medicine, University of California, San Francisco, San Francisco, CA, ⁶Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA
Background/Purpose: MR-based T1rho relaxation time mapping allows non-invasive quantification of early cartilage deterioration, while high-resolution peripheral quantitative computed tomography (HR-pQCT) can detect early changes in…
Abstract Number: 587 • 2017 ACR/ARHP Annual Meeting
Detection of Structural Lesions on T1 Weighted MRI Versus Radiography of the Sacroiliac Joints in Early Axial Spa: 2-Year Data
Walter P. Maksymowych¹, Pascal Claudepierre², Manouk de Hooge³, Robert G. Lambert⁴, Robert B.M. Landewé⁵, Anna Molto⁶, Désirée van der Heijde³, Jack F Bukowski⁷, Heather Jones⁸, Isabelle Logeart⁹, Lisa Marshall⁸, Ronald Pedersen¹⁰, Annette Szumski¹¹, Bonnie Vlahos¹² and Maxime Dougados¹³, ¹Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ²Universite Paris Est Creteil, Paris, France, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University of Alberta, Edmonton, AB, Canada, ⁵Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, ⁶Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ⁷Clinical Affairs, Pfizer, Collegeville, PA, ⁸Inflammation & Immunology Global Medical Affairs, Pfizer, Collegeville, PA, ⁹Medical Affairs, Pfizer, France, Paris, France, ¹⁰Department of Biostatistics, Pfizer, Collegeville, PA, ¹¹inVentiv Health, Princeton, NJ, ¹²Clinical Sciences, Pfizer, Collegeville, PA, ¹³Hopital Cochin, Paris Descartes University, Paris, France
Background/Purpose: At the SI joint (SIJ) level, several methods exist for evaluating structural damage, e.g., MRI, CT scan, radiographs. In EMBARK (NCT01258738) and DESIR (NCT01648907),…
Abstract Number: 2000 • 2017 ACR/ARHP Annual Meeting
MRI Contributes to Accurate and Early Diagnosis of Non-Radiographic HLA-B27 Negative Axial Spondyloarthritis
Chun-Chi Lu¹, Guo-Shu Hunag², Tony Szu-Hsien Lee³, En Chao⁴, Hsiang-Cheng Chen², Shi-Jye Chu², Feng-Cheng Liu², San-Yuan Kao², Tsung-Yun Hou², Chen-Hung Chen⁵, Sin-Yi Lyu⁶ and Deh-Ming Chang⁷, ¹University of Washington; Tri-Service General Hopsital, National Defense Medical Center, Seattle, WA, ²Tri-Service General Hopsital, National Defense Medical Center, Taipei, Taiwan, ³National Taiwan Normal University, Taipei, Taiwan, ⁴Tri-Service General Hospital Songshan branch, National Defense Medical Center, Taipei, Taiwan, ⁵Taipei Tzu Chi Hospital, Taipei, Taiwan, ⁶Taoyuan General Hospital, Ministry of Health and Welfare, Taipei, Taiwan, ⁷Tri-Service General Hospital, National Defense Medical Center; Taipei Veteran General Hospital, Taipei, Taiwan
Background/Purpose: According to the ASAS classification criteria for axial spondyloarthritis (SpA), the presence of structure changes of sacroiliac (SI) joints such as sclerosis, bone erosion,…
Abstract Number: 588 • 2017 ACR/ARHP Annual Meeting
Inflammatory Lesions of the Sacroiliac Joints, but Not of the Spine, Are of High Utility for Recent Onset Axial Spondyloarthritis Recognition
Anna Molto¹, Laure Gossec², Violaine Foltz², Romain Beaufort³, Jean Denis Laredo⁴, Pascal Richette⁵, Philippe Dieude⁶, Philippe Goupille⁷, Antoine Feydy⁸ and Maxime Dougados⁹, ¹Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³Private Practice,, Paris, France, ⁴Radiology Department, Lariboisière Hospital, Paris, France, ⁵Rheumatology Department, Université Paris Diderot, Paris, France, ⁶Université Paris-Diderot, Paris, France, ⁷Université François-Rabelais, Tours, France, ⁸Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁹Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: only scarce data are available regarding the prevalence of MRI inflammatory lesions of the sacroiliac joints (SIJ) or the spine suggestive of axial Spondyloarthritis…

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