Abstracts tagged "MRI"

Abstract Number: 953 • 2018 ACR/ARHP Annual Meeting
Evaluating MRI-Detected Knee Inflammation Prior to Total Knee Replacement As a Predictive Biomarker of Clinically Important Pain Reduction Two Years Later
Manjinder Kaur¹, Lili Zhou², Erin L. Ashbeck², Ernest Vina³, Frank Roemer⁴, Ali Guermazi⁵, David J. Hunter⁶ and C. Kent Kwoh^1,2, ¹Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, ²University of Arizona Arthritis Center, Tucson, AZ, ³University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, USA, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶University of Sydney, Sydney, Australia
Background/Purpose: Some patients do not experience clinical improvement after total knee replacement (TKR). Presence of structural abnormalities on MRI before surgery may inform pain prognosis…
Abstract Number: 2908 • 2018 ACR/ARHP Annual Meeting
Agreement between Ultrasound and Whole Body Magnetic Resonance Imaging Assessment of Joint Inflammation and Enthesitis in Rheumatoid Arthritis Patients
Sin Ngai Ng¹, Mette Bjørndal Axelsen², Mikkel Østergaard³, Iris Eshed⁴, Merete Lund Hetland², Jakob M. Møller⁵, Susanne J Pedersen^6,7 and Lene Terslev⁸, ¹Medicine, Queen Elizabeth Hospital , Hong Kong, Hong Kong, Hong Kong, ²Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, ⁵Dept. of Radiology, Copenhagen University Hospitals, Herlev and Gentofte, Copenhagen, Denmark, ⁶Depart of Rheumatology VRR, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁷Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁸Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark
Background/Purpose: To evaluate the agreement between ultrasound (US), whole body magnetic resonance imaging (WBMRI) and clinical assessment of joint inflammation and enthesitis in rheumatoid arthritis…
Abstract Number: 14L • 2017 ACR/ARHP Annual Meeting
Miv-711, a Novel Cathepsin K Inhibitor Demonstrates Evidence of Osteoarthritis Structure Modification: Results from a 6 Month Randomized Double-Blind Placebo-Controlled Phase IIA Trial
Philip G. Conaghan¹, Michael A Bowes², Sarah R. Kingsbury¹, Alan Brett², Gwenael Guillard², Åsa Jansson³, Cecilia Wadell³, Richard Bethell³ and John Öhd³, ¹University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³Medivir AB, Huddinge, Sweden

Background/Purpose: The need for drugs that achieve structure modification in OA is imminent but their development has been burdened by the need for large, long…
Abstract Number: 720 • 2017 ACR/ARHP Annual Meeting
Ambulatory Blood Pressure and Skin Sodium Concentrations in Patients with Systemic Lupus Erythematosus
Daniel Carranza Leon¹, Cecilia P. Chung¹, Michelle J. Ormseth², Annette M. Oeser³, Ping Wang⁴, Adriana Marton¹, Jens Titze³ and C. Michael Stein¹, ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Rheumatology, Vanderbilt Medical Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Radiology, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Ambulatory 24-hour blood pressure and nocturnal blood pressure measurements are better predictors of cardiovascular risk than office blood pressure. Patients with systemic lupus erythematosus…
Abstract Number: 2806 • 2017 ACR/ARHP Annual Meeting
Integrated Longitudinal Analysis Increases Precision and Reduces Bias: A Comparative 5-Year Analysis in the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Désirée van der Heijde¹, Maxime Dougados³, Pascal Claudepierre⁴, Antoine Feydy⁵, M. Reijnierse⁶, Damien Loeuille⁷ and Robert B.M. Landewé⁸, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³Paris-Descartes University,, Paris, France, ⁴Hôpital Henri Mondor, Créteil, France, ⁵Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ⁸University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Evaluation of imaging is important in spondyloarthritis (SpA) research, but loss to follow up often jeopardizes interpretation of the evaluation. The Interpretation may further…
Abstract Number: 741 • 2017 ACR/ARHP Annual Meeting
Cardiac MRI in Systemic Sclerosis As Prognostic Tool of Cardiac Mortality in Symptomatic Patients
Silvia Bosello¹, Giovanni Canestrari¹, Enrico De Lorenzis¹, Gerlando Natalello², Federico Parisi¹, Agostino Meduri³, Riccardo Marano³, Gianfranco Ferraccioli⁴ and Elisa Gremese⁵, ¹Division of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ²Division of Rhematology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ³Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ⁴Institute of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ⁵Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy
Background/Purpose: Cardiac involvement is a relevant prognostic determinant of outcome in Systemic Sclerosis (SSc). Since the role of cardiac MRI (CMR) is still uncertain, we…
Abstract Number: 2912 • 2017 ACR/ARHP Annual Meeting
The Neural Correlates of Inflammation in RA: A Multi-Modal MRI Study
Andrew Schrepf¹, Chelsea Cummiford¹, Eric Ichesco¹, Tony Larkin¹, Steven E. Harte¹, Richard E. Harris¹, Alison Murray², Gordon Waiter³, Daniel J. Clauw⁴ and Neil Basu⁵, ¹Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Aberdeen Brain Imaging Center, University of Aberdeen, Aberdeen, United Kingdom, ³Aberdeen Brain Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ⁴Chronic Pain & Fatigue Research Center, University of Michigan, Ann Arbor, MI, ⁵Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom
Background/Purpose: Inflammation is the hallmark of disease activity in rheumatoid arthritis (RA). RA is characterized by fatigue and cognitive/affective disturbances, and these symptoms often worsen…
Abstract Number: 872 • 2017 ACR/ARHP Annual Meeting
Myocardial Abnormalities Improve in RA Patients Treated Actively – a Cardiac MRI Follow-up Study
Riitta Koivuniemi^1,2, Mia Holmström³, Antti Kuuliala², Sari Kivistö³ and Marjatta Leirisalo-Repo^1,2, ¹Rheumatology, University of Helsinki, Helsinki, Finland, ²Rheumatology, Helsinki University Hospital, Helsinki, Finland, ³Radiology, HUS Medical Imaging Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Background/Purpose: Patients with RA are prone to develop myocardial dysfunction, in which chronic inflammation is suggested to play an important role. We have previously shown…
Abstract Number: 2947 • 2017 ACR/ARHP Annual Meeting
Do Bone Marrow Lesions Reactivate Endochondral Ossification Leading to Osteophyte Genesis? Data from the Osteoarthritis Initiative
Leticia Deveza¹, Laurence Teoh², Elena Ochoa-Albiztegui³, Ali Guermazi⁴, Frank Roemer^4,5 and David Hunter¹, ¹Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ²Department of General Medicine, Middlemore Hospital, Auckland, New Zealand, Auckland, New Zealand, ³Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, New York, NY, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, USA, Boston, MA, ⁵Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Osteophytes are formed through reactivation of endochondral ossification. In adults, reactivation of endochondral ossification may occur in the context of fracture repair. As yet,…
Abstract Number: 1386 • 2017 ACR/ARHP Annual Meeting
Tenosynovitis in the Forefoot at Disease Presentation Is Specific for RA: Results from a Cross-Sectional MRI Study in Early Arthritis
Yousra J. Dakkak¹, Debbie M. Boeters², Annette H.M. van der Helm-van Mil² and M. Reijnierse³, ¹Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The foot is a preferential location for rheumatoid arthritis (RA)-manifestation, but physical examination of the metatarsophalangeal (MTP) joints is difficult. Magnetic Resonance Imaging (MRI)…
Abstract Number: 2964 • 2017 ACR/ARHP Annual Meeting
Structural Damage in Patients with Very Early RA Is Predicted with Clinical Measures of Baseline Disease Activity: DAS28 (CRP), SDAI, M-DAS28 and RAPID3 but Not CDAI
Edward C. Keystone¹, H Ahmad², Yusuf Yazici³, X Liu² and MJ Bergman⁴, ¹University of Toronto, Toronto, ON, Canada, ²Bristol-Myers Squibb, Princeton, NJ, ³New York University School of Medicine, New York, NY, ⁴Drexel University College of Medicine, Philadelphia, PA
Background/Purpose: Clinicians rely on time-efficient, validated disease activity assessments to help accurately predict disease progression in patients with RA. The utility of the Routine Assessment…
Abstract Number: 1504 • 2017 ACR/ARHP Annual Meeting
More Than 10 Percent Patients with Recent Onset Chronic Mechanical Back Pain Fulfill the Modified NY Criteria for Sacroiliitis
Anna Molto¹, Laure Gossec², Violaine Foltz², Romain Beaufort³, Jean Denis Laredo⁴, Pascal Richette⁵, Philippe Dieude⁶, Philippe Goupille⁷, Antoine Feydy⁸ and Maxime Dougados⁹, ¹Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ²UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ³Private Practice,, Paris, France, ⁴Radiology Department, Lariboisière Hospital, Paris, France, ⁵Rheumatology Department, Université Paris Diderot, Paris, France, ⁶Université Paris-Diderot, Paris, France, ⁷Department of Rheumatology, CHRU de Tours; and Université François-Rabelais de Tours, Tours, France, ⁸Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁹Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: only scarce data are available regarding the diagnostic value of pelvic Xrays abnormalities suggestive of axial spondyloarthritis (axSpA) in patients with recent onset back…
Abstract Number: 235 • 2017 ACR/ARHP Annual Meeting
MRI in Rheumatoid Arthritis: Does Quantifying the Number of Erosive Lesions Improve Detection of Subtle Erosive Progression Compared to the Omeract RA MRI Scoring System?
Ulf Sundin¹, Anna-Birgitte Aga², Tore K Kvien³, Siri Lillegraven⁴ and Espen A. Haavardsholm⁴, ¹*Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Early detection of erosive progression is an important application of MRI in RA. For research purposes the OMERACT Rheumatoid Arthritis MRI Scoring system (RAMRIS)…
Abstract Number: 1831 • 2017 ACR/ARHP Annual Meeting
A Positive MRI of the Sacroiliac Joints Is Not Specific for Axial Spondyloarthritis but Frequently Occurs in Healthy Individuals
Janneke de Winter¹, Manouk de Hooge², Marleen van de Sande¹, Lonneke van Hoeven³, Jet de Jong¹, Anoek de Koning², Inger Jorid Berg⁴, Roberta Ramonda⁵, Dominique Baeten^1,6, Désirée van der Heijde⁷, Angelique Weel⁸ and Robert B.M. Landewé⁹, ¹Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁴Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, ⁶UCB Pharma, Slough, United Kingdom, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁹Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands
Background/Purpose: Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%) but the specificity is not well known, hence we compared…
Abstract Number: 307 • 2017 ACR/ARHP Annual Meeting
Biochemical Intervertebral Disc Alterations in Patients with Low Back Pain and Radiculopathy
Philipp Sewerin¹, Christoph Schleich², Ruben Sengewein³, Matthias Schneider⁴ and Benedikt Ostendorf¹, ¹Department and Hiller-Research-Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ²Dep. for diagnostic and interventional Radiology, Heinrich-Heine University, Duesseldorf, Germany, ³Department and Hiller Research Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ⁴Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
Background/Purpose: To assess the glycosaminoglycan (GAG) content of lumbar intervertebral discs (IVD) in patients with low back pain (LBP) and radiculopathy using glycosaminoglycan chemical exchange…

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