Abstracts tagged "MRI"

Abstract Number: 2790 • 2014 ACR/ARHP Annual Meeting
CMR with Quantitative T2 Mapping in Patients with Active SLE
Stacy P. Ardoin¹, Wael N. Jarjour², Subha V. Raman², Amanda Kibler² and Tam Tran², ¹Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ²Ohio State University, Columbus, OH
Background/Purpose: Cardiovascular (CV) disease is an important cause of morbidity in systemic lupus erythematosus (SLE) . Myocarditis is considered an uncommon complication of SLE…
Abstract Number: 1578 • 2014 ACR/ARHP Annual Meeting
Abatacept Improves Synovitis As Assessed By Magnetic Resonance Imaging (MRI) in Psoriatic Arthritis – Preliminary Analysis from a Single Centre, Placebo-Controlled, Crossover Study
Agnes Szentpetery¹, Eric J. Heffernan², Muhammad Haroon³, Phil Gallagher¹, Anne-Marie Baker¹, Martina Cooney¹ and Oliver FitzGerald¹, ¹Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ²Radiology, St. Vincent's University Hospital, Dublin, Ireland, ³Newmarket On Fergus, Cork University Hospital, Cork, Ireland
Background/Purpose Abatacept is a soluble, fully human fusion protein which selectively inhibits T-cell activation via the CD80/CD86:CD28 co-stimulation pathway and decreases serum levels of inflammatory…
Abstract Number: 1180 • 2014 ACR/ARHP Annual Meeting
Dynamic Magnetic Resonance Imaging in the Assessment of the Response to Certolizumab Pegol in Rheumatoid Arthritis Patients: Results from a Phase IIIb Randomized Study
Mikkel Østergaard¹, Mette Bjørndal Axelsen², Lennart T.H. Jacobsson³, Christopher Schaufelberger³, Michael Sejer Hansen⁴, Johannes W.J. Bijlsma⁵, Anna Dudek⁶, Maria Rell-Bakalarska⁷, Fabienne Staelens⁸, Robert Haake⁹, Britt Sundman-Engberg¹⁰ and Henning Bliddal¹¹, ¹Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, ²Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, ³Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ⁴Department of Rheumatology, Gentofte Hospital, Copenhagen, Denmark, ⁵Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁶Medica Pro Familia, Warsaw, Poland, ⁷Rheuma Medicus, Warsaw, Poland, ⁸UCB Pharma, Brussels, Belgium, ⁹UCB Pharma, Raleigh, NC, ¹⁰UCB Pharma, Stockholm, Sweden, ¹¹The Parker Institute, Department of Rheumatology, Frederiksberg, Denmark
Background/Purpose Magnetic resonance imaging (MRI) can detect early joint inflammation with high sensitivity, without use of radiation. The MARVELOUS study (NCT01235598), using the OMERACT RA…
Abstract Number: 205 • 2014 ACR/ARHP Annual Meeting
Natural History and Clinical Significance of Meniscal Tears over 8 Years in a Largely Non-Osteoarthritic Cohort
Hussain Ijaz Khan¹, Dawn Aitken¹, Changhai Ding², Leigh Blizzard³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicutinni⁵ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia
Background/Purpose: Meniscal tears are a key player in knee osteoarthritis (OA) and family history of the disease has been shown to play an important role.…
Abstract Number: 2601 • 2014 ACR/ARHP Annual Meeting
Serum Biomarkers Associated with Changes in ASDAS and MRI Following Treatment of Ankylosing Spondylitis with Golimumab
Robert D. Inman¹, Xenofon Baraliakos², Kay-Geert A. Hermann³, Jürgen Braun⁴, Atul A. Deodhar⁵, Désirée van der Heijde⁶, Stephen Xu⁷ and Benjamin Hsu⁷, ¹Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ³Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Oregon Health and Sciences University, Portland, OR, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Janssen Research & Development, LLC., Spring House, PA
Background/Purpose Serum biomarkers that can predict subsequent clinical or imaging outcomes would aid decision-making in the management of ankylosing spondylitis (AS). Using data from the…
Abstract Number: 1581 • 2014 ACR/ARHP Annual Meeting
Inflammatory Back Pain in Psoriasis and Psoriatic Arthritis Is Suggestive of Undiagnosed Spondyloarthropathies
Majed Khraishi¹, Heather Jones^2,3 and Annette Szumski⁴, ¹Clinical Professor of Medicine (Rheumatology), Memorial University of Newfoundland, St. John's, NF, Canada, ²Inflammation & Immunology, Pfizer Inc., Collegeville, PA, ³Pfizer Inc., Collegeville, PA, ⁴Specialty Care, Pfizer Inc., Collegeville, PA
Background/Purpose: Patients with psoriasis (Ps) and/or psoriatic arthritis (PsA) may have clinical features suggestive of axial skeletal abnormalities and should be assessed for the presence…
Abstract Number: 1024 • 2014 ACR/ARHP Annual Meeting
Racial Differences in Biochemical Knee Cartilage Composition Between African American and Caucasian American Women with MR-Based T2 Relaxation Time Measurements – Data from the Osteoarthritis Initiative
Martin Kretzschmar¹, Ursula Heilmeier², Aihong Yu³, Gabby B. Joseph⁴, Felix Liu⁵, Hans Liebl³, Charles E. McChulloch⁶, Michael C. Nevitt⁷, Nancy E. Lane⁸ and Thomas M Link⁹, ¹Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging,, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, ⁴Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San FRancisco, CA, ⁵University of California at San Francisco, San Francisco, CA, ⁶Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, ⁷Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁸Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁹Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: To determine whether knee cartilage composition differs between African-American and matched Caucasian-American women at risk for Osteoarthitis (OA) using in-vivo 3T MRI T2 relaxation…
Abstract Number: 215 • 2014 ACR/ARHP Annual Meeting
External Hip Adduction Moment and Progression of Medial Tibiofemoral Cartilage Damage and Bone Marrow Lesions in Persons with Knee Osteoarthritis
Kirsten Moisio¹, Alison H. Chang², Ali Guermazi³, Joan S. Chmiel¹, Orit Almagor¹, Pottumarthi Prasad¹, Yunhui Zhang¹, Karen W. Hayes¹, Laura Belisle¹, Jamie Rayahin⁴ and Leena Sharma¹, ¹Northwestern University, Chicago, IL, ²Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, ³Radiology, Boston University School of Medicine, Boston, MA, ⁴University of Illinois at Chicago, Chicago, IL
Background/Purpose Gait mechanics at the hip may affect medial joint loading at the knee in persons with knee OA. Greater external hip adduction moment (reflecting…
Abstract Number: 2597 • 2014 ACR/ARHP Annual Meeting
Impact of Repeating Imaging of the Sacro-Iliac Joints over One Year on the Classification According the ASAS Axial Spa Criteria of Patients
Pauline Bakker¹, Manouk de Hooge¹, Rosaline van den Berg², Floris van Gaalen², Monique Reijnierse¹, T.W.J. Huizinga¹ and Désirée van der Heijde³, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: It is known that in axial spondyloarthritis (axSpA) inflammatory lesions on MRI of the SI joints (MRI-SI) can change over time. The usefulness of…
Abstract Number: 1424 • 2014 ACR/ARHP Annual Meeting
Bone Erosions in Patients with RA: Exploring the Impact of the Anatomy of Interest on the Relationship Between MRI and X-Ray Erosion Detection
Michael Tomizza¹, Isabel Rodrigues¹, Matthew Jessome¹, Joshua Barbosa¹, Karen Beattie², William G. Bensen², Raja Bobba², Alfred Cividino², Patrick D. Emond², Karen Finlay³, Chris Gordon², Lawrence Hart², George Ioannidis², Erik Jurriaans³, Melissa Koh¹, Maggie Larche², Arthur Lau², Naveen Parasu³, Ruben Tavares², Stephen Tytus², Hao Wu¹ and Jonathan D. Adachi^1,2, ¹McMaster University, Hamilton, ON, Canada, ²St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ³Radiology, Hamilton Health Sciences, Hamilton, ON, Canada
Background/Purpose: Detection of bone erosions in patients with RA is critical in clinical practice, with treatment initiation and effectiveness largely based on limiting erosive progression.…
Abstract Number: 925 • 2014 ACR/ARHP Annual Meeting
Cortical Reorganization after Duloxetine Treatment-Related Pain Decrease in Knee Osteoarthritis
Pascal Tetreault¹, Marwan Baliki¹, Etienne Vachon-Presseau¹, Renita Evonne Yeasted², Thomas J. Schnitzer³ and A. Vania Apkarian^1,4, ¹Physiology, Northwestern University, Chicago, IL, ²PM&R, Northwestern University, Chicago, IL, ³PM&R and Int Med, Northwestern University, Chicago, IL, ⁴Anaesthesia and Surgery, Northwestern University, Chicago, IL
Background/Purpose: Structural brain properties of patients coping with chronic painful conditions are becoming better understood but knowledge on how pain treatment affects these properties is…
Abstract Number: 2581 • 2014 ACR/ARHP Annual Meeting
Clinically Active Non-Radiographic Axial Spondyloarthritis Patients Who Initially Have a Negative MRI and Normal CRP May Develop a Positive MRI or Elevated CRP at a Later Timepoint
Xenofon Baraliakos¹, Joachim Sieper², Su Chen³, Aileen L. Pangan³ and Jaclyn K. Anderson³, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Charité Universitätsmedizin Berlin, Berlin, Germany, ³AbbVie Inc., North Chicago, IL
Background/Purpose: Patients (pts) with non-radiographic axial spondyloarthritis (nr-axSpA) and active disease may have objective evidence of inflammation, either as bone marrow edema (BME) on magnetic…
Abstract Number: 1193 • 2014 ACR/ARHP Annual Meeting
Diagnostic value of Contrast-Enhanced MR-Angiography in diagnosing large Vessel Vasculitis
Sabine Adler¹, Marco Sprecher¹, Harald Bonel², Thorsten Klink² and Peter M. Villiger³, ¹Rheumatology, Immunology, Allergology, University Hospital Bern, Bern, Switzerland, ²Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Bern, Switzerland, ³Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland
Background/Purpose Diagnosis of large-vessel vasculitis (LVV) remains difficult despite clinical and serological signs and symptoms. Detection by histology might be unavailable in exclusive thoracic or…
Abstract Number: 897 • 2014 ACR/ARHP Annual Meeting
Resting State Functional Connectivity Differs Between Chronic Fatigue Syndrome Patients and Healthy Controls
Jason Craggs¹, Charles Gay¹, Andrew O'Shea¹, Ricky Madhavan², Donald Price³, Michael Robinson¹ and Roland Staud⁴, ¹Clinical & Health Psychology, University of Florida, Gainesville, FL, ²Medicine/Rheumatology, University of Florida, Gainesville, FL, ³Maxillo-Facial Surgery, University of Florida, Gainesville, FL, ⁴Dept Med/Rheum/Clin Immun Div, Univ of Florida Med Ctr/JHMHC, Gainesville, FL
Background/Purpose: Examining neural activity in the absence of task (i.e. resting state) is an active area of research. Functional connectivity, defined as correlations in BOLD…
Abstract Number: 2577 • 2014 ACR/ARHP Annual Meeting
The Ankylosing Spondylitis Disease Activity Score More Closely Reflects MRI Parameters of Sacroiliitis Than the Bath Ankylosing Spondylitis Disease Activity Index in Patients with Non-Radiographic Axial Spondyloarthritis
Walter P. Maksymowych¹, S Wichuk¹, H Jones², A Szumski³, L Marshall², J Bukowski² and RG Lambert⁴, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Pfizer Inc., Collegeville, PA, ³Specialty Care, Pfizer Inc., Collegeville, PA, ⁴Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Validation of clinical measures of disease in non-radiographic axial SpA (nr-axSpA) has been limited, especially using inflammatory and structural lesions on MRI as gold…

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