Abstracts tagged "monocytes and rheumatoid arthritis (RA)"

Abstract Number: 774 • 2013 ACR/ARHP Annual Meeting
Citrullination Of ENA-78/CXCL5 Changes Its Receptor Affinity From CXCR2 To CXCR1 and Induces Monocyte Migration
Ken Yoshida¹, Alisa E. Koch^1,2, Ray A. Ohara³, Phillip L. Campbell¹, M. Asif Amin¹, David A. Fox¹ and Jeffrey H. Ruth⁴, ¹Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, ²VA Medical Service, Ann Arbor, MI, ³University of Michigan Medical School, Ann Arbor, MI, ⁴Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI
Background/Purpose: We previously showed that citrullinated epithelial-derived neutrophil-activating peptide 78/CXCL5 (citENA-78/CXCL5) was significantly higher in rheumatoid arthritis (RA) synovial fluids (SFs) compared to osteoarthritis (OA)…
Abstract Number: 881 • 2012 ACR/ARHP Annual Meeting
Microrna-155 Regulates Chemokines and Chemokine Receptors in Rheumatoid Arthritis Monocyte
Aziza Elmesmari¹, Derek S. Gilchrist¹, Alasdair R. Fraser¹, Diane Vaughan¹, Ross McQueenie², Gerard J. Graham¹, James Brewer³, Iain B. McInnes¹ and Mariola Kurowska-Stolarska¹, ¹Immunology, Institute of Infection,Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ²Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ³Immunology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Rheumatoid arthritis (RA) is characterized by synovial tissue inflammation leading to joint destruction. Monocytes/macrophages are major effector cells in RA synovitis, principally by releasing…

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