ACR Meeting Abstracts

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Abstracts tagged "meta-analysis"

  • Abstract Number: 0141 • ACR Convergence 2022

    Is Rituximab Associated with Worse Outcomes in COVID-19 Patients? A Meta-analysis

    Yasmin Gerais1, Chenyu Sun1, Bethany King2, Scott Lowe3, Biniyam Mohammed1, Rachel Bentley3, Yaru Li4, Binyu Wei5 and Chuanhui Xu6, 1Ascension Saint Joseph hospital, Chicago, IL, 2MercyOne Des Moines Medical center, Des Moines, IA, 3College of Osteopathic Medicine, Kansas City University, Kansas, MO, 4Swedish Hospital, Chicago, IL, 5Harvard Medical School, Boston, MA, 6Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: Rituximab targets the CD20 antigen to deplete B cells and is indicated for a number of autoimmune diseases and other conditions. Accumulating data suggest…
  • Abstract Number: 2169 • ACR Convergence 2022

    Cardiac Rhythm and Conduction Abnormalities in Systemic Sclerosis-meta-analysis

    Drashti Antala1, Angkawipa Trongtorsak1, Qingqing Meng1, Akshaya Ramachandran1, Aanshi Patel2, Pabitra Adhikari1, Prasun Pudasainee1 and Krutarth Pandya3, 1Ascension Saint Francis hospital, Evanston, IL, 2B.J. Medical College, Ahmedabad, Ahmedabad, India, 3Trumbull Regional Medical Centre, Warren, OH

    Background/Purpose: Systemic sclerosis( SSc) can primarily cause repeated focal ischaemic insults in the myocardium and result in irreversible myocardial fibrosis. Myocardial involvement, when becomes clinically…
  • Abstract Number: 0328 • ACR Convergence 2022

    Predicting Progression from Undifferentiated to Definitive Connective Tissue Diseases: A Systematic Review and Meta-analysis

    Sarah Dyball1, Mia Rodziewicz1, Claudia Mendoza Pinto2, Ian N. Bruce3 and Ben Parker4, 1The University of Manchester, Manchester, United Kingdom, 2Systemic Autoimmune Diseases Research Unit, High-Specialty Medical Unit-CIBIOR, Mexican Social Security Institute, Puebla, Mexico, 3Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, 4Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

    Background/Purpose: Undifferentiated connective tissue disease (UCTD) encapsulates a broad range of conditions including incomplete forms of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc), some…
  • Abstract Number: 0426 • ACR Convergence 2022

    The Relative Efficacy of Biologic and Targeted Synthetic DMARDs in Ankylosing Spondylitis: A Network Meta-Analysis

    Jesus Diaz1, Guillermo Quiceno2, Cathy Lee Ching3 and Adela Castro4, 1Hamilton Medical Center, Chattanooga, TN, 2UT Southwestern Medical Center, Dallas, TX, 3University of Mississippi Medical Center, Jackson, MS, 4Hamilton Physician Group-Specialty Care, Dalton, GA

    Background/Purpose: There is an unmet medical need for the treatment of patients with active ankylosing spondylitis (AS) who have an inadequate response to NSAIDs. Prior…
  • Abstract Number: 0108 • ACR Convergence 2021

    Efficacy of SARS-CoV-2 Vaccine in Patients with Rheumatic Diseases: A Systematic Review and Meta-Analysis

    Akhil Sood1, Vijaya Murthy1 and Emilio Gonzalez2, 1University of Texas Medical Branch, League City, TX, 2University of Texas Medical Branch (utmb Health), Galveston, TX

    Background/Purpose: The mRNA-based SARS-CoV-2 vaccine has shown efficacy in large vaccine trials. However, patients on immunosuppressive therapies including those with rheumatic disease (RD) were excluded.…
  • Abstract Number: 0109 • ACR Convergence 2021

    COVID-19 Infection and Outcomes in Patients with Rheumatic Diseases: A Systematic Review and Meta-Analysis

    Akhil Sood1, Ronak Gandhi2, Vijaya Murthy1, Emilio Gonzalez3 and Mukaila Raji2, 1University of Texas Medical Branch, League City, TX, 2University of Texas Medical Branch, Galveston, TX, 3University of Texas Medical Branch (utmb Health), Galveston, TX

    Background/Purpose: Early studies published at the beginning of COVID-19 pandemic suggested lower risk of COVID-19 and less severe disease course in patients with rheumatic diseases…
  • Abstract Number: 0669 • ACR Convergence 2021

    Early-Onset Gout (EOG) Patients Are an Important and Recalcitrant Phenotype Warranting Further Investigation: A Systematic Review

    Anthony Amatucci1, Brian LaMoreaux2 and David Bulbin3, 1Horizon Therapeutics, West Orange, NJ, 2Horizon Therapeutics plc, Deerfield, IL, 3Geisinger Health System, Danville, PA

    Background/Purpose: Data suggests that the number of patients with early-onset gout (EOG), defined as patients under the age of 40 years, is increasing1. There is…
  • Abstract Number: 0829 • ACR Convergence 2021

    Tapering and Withdrawal of Biologics or Targeted Synthetic Disease-Modifying Antirheumatic Drugs in Patients with Inflammatory Arthritis: A Systematic Review and Meta-Analyses of Randomised Trials

    Line Uhrenholt1, Robin Christensen2, Wilfred K Dinesen3, Caroline Liboriussen3, Stine Andersen3, Lene Dreyer1, Annette Schlemmer4, Ellen-Margrethe Hauge5, Conni Skrubbeltrang6 and Salome Kristensen1, 1Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, 2Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen & Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Copenhagen, Denmark, 3Department of Clinical Medicine, Aalborg University, Aalborg, Denmark, 4Department of Rheumatology, Randers Regional Hospital, Randers, Denmark, 5Aarhus University Hospital, Aarhus, Denmark, 6Medical Library, Aalborg University Hospital, Aalborg, Denmark

    Background/Purpose: Tapering and withdrawal of biological or targeted synthetic disease-modifying antirheumatic drugs (bDMARDs or tsDMARDs) in patients with inflammatory arthritis (IA) in remission or low…
  • Abstract Number: 1304 • ACR Convergence 2021

    Increased Risk of Vertebral Fracture Among Patients with Psoriatic Arthritis: A Systematic Review and Meta-analysis

    Patompong Ungprasert1, Nipith Charoenngam2, Ben Ponvilawan3, Jerapas Thongpiya4 and Pitchaporn Yingchoncharoen3, 1Cleveland Clinic, Cleveland Heights, OH, 2Mount Auburn Hospital, Boston, MA, 3Mahidol University, Bangkok, Thailand, 4Mahdiol University, Bangkok, Thailand

    Background/Purpose: Increased risk of vertebral fracture (VF) has been documented in several autoimmune diseases as a result of excessive inflammatory burden and use of corticosteroids.…
  • Abstract Number: 1384 • ACR Convergence 2021

    A Genomic Meta-Analysis of Clinical Variables and Association with Intrinsic Molecular Subsets in Systemic Sclerosis

    Jennifer Franks1, Diana Toledo1, Viktor Martyanov1, Yue Wang2, Suiyuan Huang3, Tammara Wood1, Cathie Spino3, Robyn Domsic4, Monique Hinchcliff5, Dinesh Khanna3 and Michael Whitfield6, 1Geisel School of Medicine at Dartmouth, Hanover, NH, 2Geisel School of Medicine at Dartmouth, West Lebanon, NH, 3University of Michigan, Ann Arbor, MI, 4University of Pittsburgh, Pittsburgh, PA, 5Yale School of Medicine, Westport, CT, 6Geisel School of Medicine, Lebanon, NH

    Background/Purpose: Four intrinsic molecular subsets (Inflammatory, Fibroproliferative, Limited, Normal-like) have been identified in systemic sclerosis (SSc) that may have different clinical associations. To test this…
  • Abstract Number: 1670 • ACR Convergence 2021

    Increased Prevalence of Gastroesophageal Disease Among Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

    Patompong Ungprasert1, Nipith Charoenngam2, Ben Ponvilawan3, Pitchaporn Yingchoncharoen3 and Jerapas Thongpiya4, 1Cleveland Clinic, Cleveland Heights, OH, 2Mount Auburn Hospital, Boston, MA, 3Mahidol University, Bangkok, Thailand, 4Mahdiol University, Bangkok, Thailand

    Background/Purpose: Recent experimental studies have suggested that systemic inflammatory response could lead to impairment of lower esophageal function, resulting in gastroesophageal reflux disease (GERD). Epidemiologic…
  • Abstract Number: 1682 • ACR Convergence 2021

    Impact of Type, Dose and Duration of Oral Polyunsaturated Fatty Acid Supplementation on Disease Activity in Inflammatory Rheumatic Diseases: A Systematic Literature Review and Meta-analysis

    Johanna Sigaux1, Sylvain Mathieu2, Yann N guyen3, Pauline Sanchez4, Jean-Guillaume LETAROUILLY5, Martin Soubrier2, sebastien czernichow6, Rene-Marc FLIPO7, Jeremie Sellam8 and Claire Daïen4, 1Department of Rheumatology, Hôpital Avicenne, APHP, INSERM U1125, Université Sorbonne Paris Nord, Bobigny, France, 2Department of Rheumatology, CHU Gabriel-Montpied, Clermont-Ferrand, France, 3Department of Internal Medicine, Hôpital Beaujon, APHP nord, Université de Paris, F-92100 Clichy, France, Paris, France, 4Department of Rheumatology, CHU de Montpellier, & University of Montpellier, PhyMedExp, INSERM, CNRS UMR, Montpellier FRANCE University of Montpellier, PhyMedExp, INSERM, CNRS UMR, Montpellier, France, 5Rheumatology Department, University Hospital of Lille, Lille, France, 6Department of Nutrition, Specialized Obesity Center, Hôpital Européen Georges Pompidou, Université de Paris, Paris, France, 7Rheumatology Department, Lille University Hospital, Lille, France, 8INSERM UMRS_938, Sorbonne Université, St-Antoine Hospital, Paris, France, Paris, France

    Background/Purpose: This systematic literature review and meta-analysis aimed to better estimate the effect of oral supplementation with polyunsaturated fatty acid (PUFA; omega (n)-3 and n-6)…
  • Abstract Number: 1728 • ACR Convergence 2021

    Takayasu’s Arteritis and Pregnancy: A Meta-analysis

    Aine Gorman1, Leah Rooney2, Matthew Turk1, Louise Moore3, Jared Bierbrier4, Celine O'Brien5, Anne Clohessy6, Eamonn Molloy7, Lorraine O Neill8, Fionnuala McAuliffe9 and Douglas Veale10, 1St Vincents Hospital, Dublin, Ireland, 2St Vincent's University Hospital, Dublin, Ireland, 3Our Lady's Hospice and Care Services, Harold's Cross, Dublin 6W, Kinnegad, Ireland, 4McMaster University, Hamilton, ON, Canada, 5Perinatal Research Centre, Obstetrics and Gynaecology, School of Medicine, University College Dublin and National Maternity Hospital, Dublin, Dublin, Ireland, 6National Maternity Hopistal, Dublin, Ireland, 7St Vincent's Healthcare Group, Dublin, Ireland, 8St. Vincent's Hospital, Dublin, Ireland, 9National Maternity Hopsital Dublin, Dublin, Ireland, 10University College Dublin, Dublin, Ireland

    Background/Purpose: Takayasu’s arteritis is a systemic autoimmune disease characterised by large vessel vasculitis. It usually affects women of childbearing age, with 90% of patients diagnosed…
  • Abstract Number: 1732 • ACR Convergence 2021

    Effects of B Cell Activating Factors/B Lymphocyte Stimulator Inhibitors Added to Standard of Care on Infection in Patients with Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Ruoning Ni1, Jiayi Zheng2 and Ruru Guo3, 1Saint Agnes Healthcare, Baltimore, MD, 2Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China (People's Republic), 3Renji Hospital, Shanghai, China (People's Republic)

    Background/Purpose: The efficacy of B cell activator factor/B lymphocyte stimulator inhibitors (BAFFi/BLySi) for systemic lupus erythematosus (SLE) has been proven in clinical trials. However, it…
  • Abstract Number: 1452 • ACR Convergence 2020

    Transcriptomic Meta-analysis Reveals a Core Transcriptional Program in Murine B Cell Anergy and Implicates Immunometabolic Regulation as a Central Pathway in Maintaining Non-responsiveness of Autoreactive B-cells in Both Mouse and Man

    Isaac Harley1, Bergren Crute2, Andrew Getahun2 and John Cambier3, 1University of Colorado Anschutz Medical Campus, Aurora, CO, 2University of Colorado – Anschutz Medical Campus, Aurora, 3Univ, Aurora

    Background/Purpose: The mechanisms self-tolerance loss that lead to autoantibody-mediated autoimmune disease remain underdefined. The rapid reversibility of peripheral B-cell tolerance in murine models suggests that…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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