ACR Meeting Abstracts

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Abstracts tagged "meta-analysis"

  • Abstract Number: 0648 • ACR Convergence 2024

    Prevalence of Pulmonary Complications Among Patients with Systemic Lupus Erythematosus (SLE): A Systematic Review and Meta-analysis

    Athanasios Vassilopoulos1, Stephanos Vassilopoulos2, Jasneet Singh2, Ingrid Lazaridou2, Markos Kalligeros2, Eleftherios Mylonakis3 and Anthony M. Reginato4, 1Warren Alpert Medical School of Brown University, Providence, RI, 2Division of Internal Medicine, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island, Providence, RI, 3Department of Medicine, Houston Methodist Hospital, Houston, 4Brown University, Providence, RI

    Background/Purpose: Pleuritis remains the most common pulmonary manifestation in patients with SLE.  The prevalence of other less common complications of SLE such as: interstitial lung…
  • Abstract Number: 2614 • ACR Convergence 2024

    Risk of New Onset of Immune-Mediated Diseases After Sars-Cov-2 Infection: A Systematic Review and Meta-Analysis

    Ana Milena Gil1, Julián Barahona-Correa2, Jorge Bruce Flórez-Suárez3, Daniel Fernández-Ávila4 and Zulma Cucunubá1, 1Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogotá, Colombia, 2Division of Rheumatology, Pontificia Universidad Javeriana - Hospital Universitario San Ignacio, Bogotá, Colombia, 3Department of Immunology, Universidad Nacional de Colombia, Bogotá, Colombia, 45Hospital San Ignacio, Colombia, BOGOTA, Colombia

    Background/Purpose: The association between SARS-CoV-2 infection and the new onset of immune-mediated diseases is a topic of interest given the conflicting evidence available. This systematic…
  • Abstract Number: 0726 • ACR Convergence 2024

    Management of ANCA Vasculitis-Associated Orbital Inflammatory Disease: A Systematic Literature Review

    Emma Neary1, Katie Healey2, Marie Clements-Baker3, Jean-Paul Makhzoum4 and Arielle Mendel5, 1McGill University, Montreal, QC, Canada, 2Memorial University of Newfoundland, St. John's, NL, Canada, 3Queen's University, Kingston, ON, Canada, 4Vasculitis Clinic, Canadian Network for Research on Vasculitides, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 5McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Ocular manifestations are common in ANCA-associated vasculitides (AAV), with orbital inflammatory disease (OID) representing a significant subset. Despite being a vision-threatening complication, OID remains…
  • Abstract Number: 0787 • ACR Convergence 2024

    Efficacy of Intra-Articular Hyaluronic Acid Injection for Nonsurgical Management of Carpometacarpal Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Clinical Trials

    Mohamed Abdelsalam1, omnia Samy2 and Asmaa al-Najjar3, 1Rheumatology, Rehabilitation and Physical medicine department - faculty of medicine -Misr University for science and technology, 6th of October, Al Jizah, Egypt, 2Faculty of medicine - Zagazig university, Al Zagazig, Egypt, 3Faculty of medicine - Al-Azhar university in Gaza, Gaza, Palestinian Territories

    Background/Purpose: Carpometacarpal osteoarthritis (CMC OA) is a painful condition affecting 21% of hand OA patients. Various treatment modalities have been explored to reduce pain and…
  • Abstract Number: 1189 • ACR Convergence 2024

    Certain Dosages of Fasinumab Provides Superior Benefits over Placebo in Mitigating Osteoarthritis Symptoms Albeit at Increased Health Detriments: A Systematic Review and Meta-Analysis

    Muhammad Sohaib Khan1, Wania Moeen2, Umm E Salma Shabbar Banatwala2, Muhammad Usman2, Umar Mahmood2, Syed Ashad Ahmed Fatmi2, Syed Muhammad Muneeb Akhtar2, Hania Shahzad3, Muhammad Talal Ibrahim4, Nisar Ahmed5, Badaruddin Sahito2 and Muhammad Sohaib Asghar6, 1Dow University of Health Sciences, Karachi, Pakistan, 2Dow University of Health Sciences, Karachi, Sindh, Pakistan, 3UC Davis Health, Sacramento, CA, 4The Ohio State University Wexner Medical Center, Columbus, OH, 5Rapido’s Clinica Familiar, Chicago, 6AdventHealth, Sebring, FL

    Background/Purpose: Fasinumab, a newly developed anti-nerve growth factor monoclonal antibody, is currently under investigation for its potential to alleviate symptoms in osteoarthritis patients. This meta-analysis…
  • Abstract Number: 1194 • ACR Convergence 2024

    Treatment Effect of Lorecivivint Across Multiple Trials in Patients with Knee OA: A Meta-analysis

    Christopher Swearingen1, Jeyanesh Tambiah2 and Yusuf Yazici3, 1Biosplice Therapeutics, Inc, San Diego, CA, 2Biosplice Therapeutics Inc., San Diego, CA, 3NYU Grossman School of Medicine, La Jolla, CA

    Background/Purpose: Lorecivivint (LOR), an intra-articular (IA) CLK/DYRK inhibitor thought to modulate inflammatory and Wnt pathways has previously appeared safe, improved patient-reported outcomes (PROs) compared with…
  • Abstract Number: 1219 • ACR Convergence 2024

    Association Between Fibromyalgia and Serum Levels of Calcitonin Gene-Related Peptide and Vascular Endothelial Growth Factor: A Meta-Analysis

    Osama Al Zoubi1, Dahlia Chavez2 and Robert Katz3, 1University of Illinois at Chicago, Chicago, IL, 2Rheumatology Associates, Rush University Medical Center, Chicago, IL, 3Rush University Medical Center, Chicago, IL

    Background/Purpose: Fibromyalgia syndrome (FMS) is characterized by generalized muscle pain, fatigue, psychological distress, cognitive dysfunction, and sleep disturbances. The physiopathology of FMS is not fully…
  • Abstract Number: 1384 • ACR Convergence 2024

    Disease-modifying Antirheumatic Drugs and Risk of Incident Interstitial Lung Disease Among Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

    Qianru Zhang1, Gregory McDermott2, Sung Hae Chang3, Pierre-Antoine Juge4, Kathleen Vanni5, Grace Qian6, Katarina Bade5, Kevin Mueller5, Emily Kowalski5, Alene Saavedra5 and Jeffrey Sparks7, 1Harard Medical School, Cambridge, 2Brigham and Women's Hospital, Brookline, MA, 3Soonchunhyang University College of Medicine, Bongmyeong-dong, Dongnam-gu, Cheonan-si, South Korea, 4Service de Rhumatologie, Hôpital Bichat - Claude-Bernard, AP-HP, Paris, Île-de-France, France, PARIS, Germany, 5Brigham and Women's Hospital, Boston, MA, 6Brigham and Women’s Hospital, Boston, MA, 7Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA

    Background/Purpose: Interstitial lung disease (ILD) is a serious extra-articular manifestation of RA, affecting 7-12% of patients and associated with three-fold increased mortality compared to RA…
  • Abstract Number: 1468 • ACR Convergence 2024

    Efficacy of bDMARDs in Early versus Established Disease in Axial Spondyloarthritis: A Meta-Analysis of Randomized Trials

    Diego Benavent1, Victoria Navarro Compán2, Dafne Capelusnik3 and Sofia Ramiro4, 1Rheumatology Department, Hospital Universitari de Bellvitge, Barcelona, Spain, CAMBRILS, Spain, 2La Paz University Hospital, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain, 3Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 4Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: The ASAS consensus definition of ‘early axial spondyloarthritis (axSpA)’ (axial symptoms ≤ 2 years) was expert-based given the scarcity of evidence1. We conducted a…
  • Abstract Number: 1471 • ACR Convergence 2024

    Sex-related Differences in Efficacy and Safety Outcomes in Axial Spondyloarthritis Randomized Clinical Trials: A Systematic Literature Review and Meta-analysis

    Angel Gao1, Jordi Pardo Pardo2, Steven Dang3, Lianne S Gensler4, Philip Mease5 and Lihi Eder6, 1Queens University, Kingston, Canada, 2University of Ottawa, Ottawa, Canada, 3Women's College Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada, 4Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 5Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 6University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada

    Background/Purpose: Limited information exists on sex-related differences in axial spondyloarthritis (axSpA) randomized controlled trials (RCTs). Through a systematic literature review and meta-analysis we aimed to assess…
  • Abstract Number: 1498 • ACR Convergence 2024

    Gender Disparities in Clinical Manifestations and Outcomes of Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis

    Mazen Allouni1, Muhammad Shamim2, Krista Topalsky3 and Omer Pamuk4, 1Case Western Reserve, University Hospitals, Cleveland Medical Center, Cleveland, OH, 2University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 3University Hospitals/ Case Western Reserve University, Shaker Heights, OH, 4University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: The clinical manifestations and outcomes of systemic lupus erythematosus (SLE) reveal notable gender differences, which may impact treatment strategies and patient outcomes. This meta-analysis…
  • Abstract Number: 0029 • ACR Convergence 2024

    Effect of Metformin on the Incidence of Total Knee Replacement: A Systematic Review and Meta-Analysis

    Syed Hasan1, Aali Furqan2, Afia Salman3, hira Khan4, Sarah Aslam5, Alishba Rizvi4, Hafsah Alim Ur Rahman3, Muhammad Ahmed Ali Fahim3, Madiha Salman3, Eman Ali3, Yumna Furqan6, Shanta bai7, Farah Yasmin8 and Muhammad Sohaib Asghar9, 1Dow University of Health Sciences, Karachi, PK., Karachi, Sindh, Pakistan, 2University of North Texas Health Science Center (UNT HSC), Texas, TX, 3Dow University of Health Sciences, Karachi, Pakistan, 4dow medical college, Karachi, Pakistan, 5Dow International Medical College, Karachi, Pakistan, 6Texas A&M School of Medicine, Dallas, TX, 7Liaquat National Hospital and Medical College, Karachi, Pakistan, 8Yale University School of Medicine, New Haven, CT 06511, U.S.A., New Haven, CT, 9AdventHealth, Sebring, FL

    Background/Purpose: Osteoarthritis (OA) is among the most common debilitating conditions, causing disability and pain in older adults. For end-stage OA, total knee replacement (TKR) is…
  • Abstract Number: 1524 • ACR Convergence 2024

    Thrombocytopenia and Systemic Lupus Erythematosus: A Meta-analysis of Observational Studies

    Alexandre Matar1 and Omer Pamuk2, 1MetroHealth, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Thrombocytopenia is one of the hematological abnormalities that can occur in patients with systemic lupus erythematosus (SLE), and it has been shown to affect…
  • Abstract Number: 0228 • ACR Convergence 2024

    Do Imaging Tests Have a Role in Predicting Progression to Rheumatoid Arthritis in People with Clinically Suspect Arthralgia? A Systematic Review & Meta-Analysis

    Ankita Gupta1, Sulaiman Anis2 and Paola de Pablo2, 1Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, 2University of Birmingham, Birmingham, United Kingdom

    Background/Purpose: Clinically suspect arthralgia (CSA) has been associated with an increased risk of developing inflammatory arthritis (IA). Subclinical inflammation on imaging tests may help to…
  • Abstract Number: 1525 • ACR Convergence 2024

    Early versus Late Lupus Nephritis: A Meta-analysis of Observational Studies

    Alexandre Matar1 and Omer Pamuk2, 1MetroHealth, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic systemic autoimmune disorder characterized by a broad range of clinical and immunological manifestations, one of which is…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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