Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1255 • ACR Convergence 2022
Rheumatologists Overcall Sacroiliitis on X-ray and MRI in Axial Spondyloarthritis Patients: Data from the BelGian Inflammatory Arthritis and SpoNdylitis cohorT (Be-GIANT)
Ann-Sophie Kathleen De Craemer¹, Manouk de Hooge², Thomas Renson³, Liselotte Deroo⁴, Gaelle Varkas³, Liesbet Van Praet⁵, Rik Joos⁶, Jan Lenaerts⁷, Mieke Devinck⁸, Lieve Gyselbrecht⁹, isabelle peene³, Kristof Thevissen¹⁰, Philippe Carron³, Filip Van den bosch¹¹ and Dirk Elewaut¹², ¹Ghent University Hospital, Gent, Belgium, ²Ghent University Hospital, Luxembourg, Luxembourg, ³Ghent University Hospital, Ghent, Belgium, ⁴Ghent University, Gent, Belgium, ⁵AZ Maria Middelares, Ghent, Belgium, ⁶Ghent University Hospital, Basel, Switzerland, ⁷Reuma Instituut Hasselt, Hasselt, Belgium, ⁸AZ Sint-Lucas, Brugge, Belgium, ⁹ASZ Aalst, Aalst, Belgium, ¹⁰Reumacentrum Genk, Genk, Belgium, ¹¹Department of Internal Medicine and Paediatrics, Ghent University and VIB Centre for Inflammation Research, Ghent, Belgium, ¹²Department of Rheumatology, Ghent University Hospital, Belgium, VIB-UGent Center for Inflammation Research, Ghent University, Heusden, Belgium
Background/Purpose: To investigate (1) agreement between local and central reading of sacroiliac joint images (X-ray and magnetic resonance imaging [MRI]) from axial spondylarthritis (axSpA) patients,…
Abstract Number: 2258 • ACR Convergence 2022
Relative Frequencies of the Spectrum of MRI Lesions in the Sacroiliac Joints of Healthy Individuals and Patients with Non-Specific Back Pain: What Is the Impact of Increasing Age?
Ulrich Weber¹, Susanne Pedersen², Mikkel Østergaard³, Pedro Machado⁴, Xenofon Baraliakos⁵, Robert G Lambert⁶ and Walter P Maksymowych⁷, ¹Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ²Rigshospitalet, København, Denmark, ³Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁴University College London, London, United Kingdom, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶University of Alberta, Edmonton, AB, Canada, ⁷Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Previous studies of patients with axial spondyloarthritis (axSpA) have demonstrated that certain MRI structural lesions in the sacroiliac joints (SIJ), notably erosions, has high…
Abstract Number: 0230 • ACR Convergence 2021
Fatigue and Inflammation in Rheumatoid Arthritis Are Already Disconnected Before Clinical Arthritis Develops
Sarah J.H. Khidir¹, Annette H.M van der Helm-van Mil¹ and Elise van Mulligen², ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Fatigue is disabling and common in Rheumatoid Arthritis (RA); the causation of fatigue in RA is multidimensional and only partially explained by inflammation. The…
Abstract Number: 0921 • ACR Convergence 2021
Effect of Secukinumab on Radiographic Progression and Inflammation in Sacroiliac Joints and Spine in Patients with Non-radiographic Axial Spondyloarthritis: 2-year Imaging Outcomes from a Phase III Randomized Trial
Juergen Braun¹, Ricardo Blanco², Helena Marzo-Ortega³, Lianne Gensler⁴, Filip Van den Bosch⁵, Stephen Hall⁶, Hideto Kameda⁷, Denis Poddubnyy⁸, Marleen van de Sande⁹, Désirée van der Heijde¹⁰, Tingting Zhuang¹¹, Anna Stefanska¹², Aimee Readie¹¹, Hanno Richards¹³ and Atul Deodhar¹⁴, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Hospital University Marqués de Valdecilla, IDIVAL, Division of Rheumatology, Santander, Spain, ³NIHR Leeds Biomedical Research Centre and University of Leeds, Leeds, United Kingdom, ⁴Department of Rheumatology, University of California San Francisco, San Francisco, CA, ⁵Dept. of Rheumatology - Ghent University Hospital, Ghent, Belgium, Ghent, Belgium, ⁶Emeritus Research and Monash University, Melbourne, Australia, Melbourne, Australia, ⁷Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Toho University, Tokyo, Japan, ⁸Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, ⁹Amsterdam UMC, University of Amsterdam, Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, ¹⁰Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹¹Novartis Pharmaceuticals Corporation, East Hanover, NJ, ¹²Novartis Ireland Limited, Dublin, Ireland, Dublin, Ireland, ¹³Novartis Pharma AG, Basel, Switzerland, ¹⁴Oregon Health & Science University, Portland, OR
Background/Purpose: Axial spondyloarthritis (axSpA) is characterized by inflammation of the sacroiliac joints (SIJ) and the spine. Secukinumab (SEC) treatment was clinically efficacious and reduced SIJ…
Abstract Number: 0305 • ACR Convergence 2021
Artificial Neural Networks Approaches to Predict Myocardial Fibrosis in Primary Sjögren Syndrome Patients Without Cardiac Symptoms
Hitomi Kobayashi¹, Yasuyuki Kobayashi², Atsuma Nishiwaki¹, Isamu Yokoe¹, Haraoka Masaki³, Eichi Takaya³, Yousuke Nagasawa¹, Noboru Kitamura¹, Masami Takei¹ and Hideki Nakamura¹, ¹Nihon University School of Medicine, Itabashi, Japan, ²St. Marianna University School of Medicine, kowasaki, Japan, ³St. Marianna University School of Medicine, Kawaski, Japan
Background/Purpose: A recent meta-analysis of cardiovascular diseases demonstrated that the odds of heart failure (HF) was more than 2.54-fold higher in primary Sjögren syndrome (pSS)…
Abstract Number: 0930 • ACR Convergence 2021
Effect of Tofacitinib on Spinal Vertebral Body and Posterolateral Element Inflammation and Structural Lesions Using the Canada-Denmark MRI Scoring System in Patients with Ankylosing Spondylitis: Results from a Phase 2 Study
Mikkel Ostergaard¹, Joseph Wu², Lara Fallon³, Sarah P Sherlock⁴, Cunshan Wang², Dona L Fleishaker², Keith S Kanik² and Walter Maksymowych⁵, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark, ²Pfizer Inc, Groton, CT, ³Pfizer Canada, Montréal, QC, Canada, ⁴Pfizer Inc, Cambridge, MA, ⁵Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada
Background/Purpose: The Canada-Denmark (CANDEN) MRI scoring system enables detailed anatomy-based evaluation of inflammatory and structural lesions in spinal vertebral bodies and posterior elements in patients…
Abstract Number: 0364 • ACR Convergence 2021
Dose Tapering of TNF Inhibitors in Patients with Axial Spondyloarthritis in Routine Care – 2-year Clinical and MRI Outcomes and Predictors of Successful Tapering
Marie Wetterslev¹, Stylianos Georgiadis², Inge Juul Sørensen³, Susanne Juhl Pedersen², Sara Nysom Christiansen⁴, Merete Lund Hetland¹, Cecilie Heegaard Brahe², Mads Bakkegaard⁵, Anne Duer⁶, Mikael Boesen⁷, Kasper Kjærulf Gosvig⁸, Jakob Møllenbach Møller⁸, Niels Steen Krogh⁹, Bente Jensen⁵, Ole Rintek Madsen⁵, Jan Christensen⁵, Annette Hansen⁵, Jesper Nørregaard⁵, Henrik Røgind⁵ and Mikkel Ostergaard¹⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁵Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ⁶Department of Radiology, Rigshospitalet, Glostrup, Copenhagen, Denmark, ⁷Department of Radiology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁸Department of Radiology, Herlev and Gentofte Hospital, Copenhagen, Denmark, ⁹ZiteLab ApS, Copenhagen, Denmark, Frederiksberg, Denmark, ¹⁰Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark
Background/Purpose: In a 2-year follow-up study of patients with axial spondyloarthritis (axSpA) in clinical remission who tapered Tumor Necrosis Factor inhibitor (TNFi) treatment according to…
Abstract Number: 1148 • ACR Convergence 2021
Prevalence and Risk Factors of Insufficiency Fractures of the Foot and Ankle Joint in Rheumatic and Musculoskeletal Diseases
Bjoern Buehring¹, Nadine Al-Azem¹, Ioana Andreica¹, David Kiefer², Uta Kiltz¹, Styliani Tsiami¹, Xenofon Baraliakos¹ and Juergen Braun¹, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Essen, Germany
Background/Purpose: Unlike fragility fractures, high-trauma and insufficiency fractures (IF) are not classically considered osteoporotic fractures. Patients with rheumatic and musculoskeletal diseases (RMD), especially those with…
Abstract Number: 0405 • ACR Convergence 2021
Retrospective Study on the Prognostic Value of Cardiac Magnetic Resonance Imaging Abnormalities in Systemic Sclerosis
Hao Cheng Shen¹, Catherine Faucher², Anne Chin³, Carl Chartrand-Lefebvre³, Ragui Chehata⁴, Julia Cadrin-Tourigny⁵, Francois-Pierre Mongeon⁶, Jean-Paul Makhzoum⁷, Océane Landon-Cardinal⁸, Josiane Bourré-Tessier⁸, Éric Rich⁹, Jean-Richard Goulet⁸, Paul R Fortin¹⁰, Jean-Luc Senécal⁸ and Sabrina Hoa⁸, ¹Department of Medicine, Université de Montréal, Montréal, QC, Canada, ²Department of Medicine, Université Laval, Québec, QC, Canada, ³Department of Radiology, Centre hospitalier de l’Université de Montréal, Montréal, QC, Canada, ⁴Department of Medicine, Université de Montréal, Montreal, Montréal, QC, Canada, ⁵Division of Non-Invasive Cardiology, Department of Specialized Medicine, Montreal Heart Institute; Department of Medicine, Université de Montréal, Montréal, QC, Canada, ⁶Division of electrophysiology, Department of Specialized Medicine, Montreal Heart Institute; Department of Medicine, Université de Montréal, Montréal, QC, Canada, ⁷Division of Internal Medicine, Hôpital Sacré-Coeur de Montréal; Department of Medicine, Université de Montréal, Montréal, QC, Canada, ⁸Division of Rheumatology, Centre hospitalier de l'Université de Montréal; Department of Medicine, Université de Montréal, Montréal, QC, Canada, ⁹Division of Rheumatology, Centre hospitalier de l’Université de Québec-Université Laval, Montréal, QC, Canada, ¹⁰CHU de Quebec - Universite Laval, Québec City, QC, Canada
Background/Purpose: Cardiac involvement is a leading cause of death in systemic sclerosis (SSc). Cardiac MRI (CMR) is useful in the early assessment of cardiac disease.…
Abstract Number: 1196 • ACR Convergence 2021
Morning Stiffness Already Associates with Systemic Inflammation and Subclinical Joint Inflammation in the Pre-RA Phase of Arthralgia
Doortje Krijbolder¹, Fenne Wouters¹, Elise van Mulligen² and Annette H.M van der Helm-van Mil¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Morning stiffness (MS) is characteristic for Rheumatoid Arthritis (RA) and associates with markers of systemic and local inflammation in RA-patients. In patients with arthralgia,…
Abstract Number: 0407 • ACR Convergence 2021
The Clinical Role of T1 Mapping Cardiac Magnetic Resonance Imaging for Detecting Cardiac Involvement in the Early Stage of Systemic Sclerosis
Munkhtuul Purevsuren¹, Masae Uehara¹, Masato Ishizuka¹, Toru Hara¹, Nobutaka Kakuda¹, Taeko Tsuji¹, Tadashi Yamazaki¹, Miyazaki Miki², Hayakazu Sumida², Ayumi Yoshizaki², Yoshihide Asano², Shinichi Sato³, Masaru Hatano¹ and Komuro Issei¹, ¹1. Department of Cardiovascular Medicine, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan., Tokyo, Japan, ²2. Department of Dermatology, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan., Tokyo, Japan, ³Department of Dermatology, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan
Background/Purpose: Systemic sclerosis (SSc) is characterized by skin and internal organs tissue fibrosis including the myocardium. Cardiovascular magnetic resonance (CMR) parametric mapping is a promising…
Abstract Number: 1362 • ACR Convergence 2021
No Change in Bone Marrow Edema of the Sacroiliac Joints and Spine After High Intensity Interval Training in PsA
Ruth Stoklund Thomsen¹, Tom Nilsen², Mari Hoff¹, Glenn Haugeberg³ and Arthur Kavanaugh⁴, ¹Dept. of Rheumatology, University Hospital of Trondheim, Norway ; Norwegian University of Science and Technology, Trondheim, Norway, Trondheim, Norway, ²Norwegian University of Science and Technology, Trondheim, Norway, Trondheim, Norway, ³Dept. of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway; Norwegian University of Science and Technology, Trondheim, Norway, ⁴University of California San Diego, La Jolla, CA
Background/Purpose: Physical activity is recommended for patients with psoriatic arthritis (PsA) especially due to the high prevalence of overweight/obesity, and the risk of comorbidities such…
Abstract Number: 0154 • ACR Convergence 2021
Utilization of Magnetic Resonance Imaging in Early Rheumatoid Arthritis: Results from a Population-based Cohort (1999-2014)
Caitrin Coffey¹, Cynthia Crowson², Cassondra Hulshizer¹, Gavin McKenzie¹, Nicholas Rhodes¹, John Davis¹ and Kerry Wright¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Early diagnosis and treatment initiation improve outcomes for patients with rheumatoid arthritis (RA). Delays to diagnosis and treatment affect patients with seronegative vs seropositive…
Abstract Number: 0425 • ACR Convergence 2021
Diagnostic Accuracy of Muscle MRI for Muscular Vasculitis in Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis: A Pilot Study
Ryuta Inaba, Daisuke Waki, Keisuke Nishimura, Tomohiro Yoshida, Kaoru Mizukawa, Shintaro Yamamoto, Osamu Iri, Kohei Yo and Hiroyuki Murabe, Department of Endocrinology and Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan
Background/Purpose: Histopathologic confirmation is the golden standard for diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), but sometimes can be difficult because of its invasion (e.g.…
Abstract Number: 1368 • ACR Convergence 2021
Characterising Exercise Capacity in Systemic Sclerosis Using Cardiac Magnetic Resonance Imaging, Skeletal Muscle Imaging and Cardiopulmonary Exercise Testing
Laura Ross¹, Benedict Costello², Dylan Hansen³, Anniina Lindqvist², Zoe Brown⁴, Andrew Burns⁴, David Prior⁴, Wendy Stevens⁴, Marcus Pianta⁴, Warren Perera⁴, Andre La Gerche² and Mandana Nikpour¹, ¹University of Melbourne at St Vincent's Hospital, Melbourne, Australia, ²Baker Heart and Diabetes Institute, Melbourne, Australia, ³St. Vincent’s Hospital Melbourne, Victoria, Australia, Adelaide, Australia, ⁴St Vincent's Hospital, Melbourne, Australia
Background/Purpose: Impaired exercise capacity contributes to functional impairment, negatively impacting individuals’ quality of life. Functional impairment is notable from early in the disease course of…

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