Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 313 • 2015 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging Outcomes Using an Intra-Articular Injection (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study
Yusuf Yazici¹, Sharmila Majumdar², Timothy E. McAlindon³, Roy Fleischmann⁴, Allan Gibofsky⁵, Marc C. Hochberg⁶, Christopher J. Swearingen¹, Anita DiFrancesco¹, Jeyanesh R. S. Tambiah¹, John Hood¹ and Nancy E. Lane⁷, ¹Samumed, San Diego, CA, ²Radiology, UCSF School of Medicine, San Francisco, CA, ³Rheumatology, Tufts Medical Center, Boston, MA, ⁴University of Texas Southwestern Medical Center, Dallas, TX, ⁵Weill Cornell Medical College and Hospital for Special Surgery, New York, NY, ⁶Department of Medicine, University of Maryland, Baltimore, MD, ⁷Center for Musculoskeletal Health, Univ of California at Davis, Sacramento, CA
Background/Purpose: Knee osteoarthritis (OA) is characterized by the destruction of articular cartilage, subchrondral bone alterations and varying degrees of synovitis. Current OA treatments are limited…
Abstract Number: 2986 • 2014 ACR/ARHP Annual Meeting
Fat Metaplasia on MRI of the Sacroiliac Joints Is a Lead Indicator of Radiographic Progression in the Spine of Patients with Ankylosing Spondylitis
Walter P. Maksymowych¹, S Wichuk², P Chiowchanwisawakit³, RG Lambert⁴ and Sj Pedersen⁵, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³Mahidol University, Bangkok, Thailand, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Fat Metaplasia on MRI of the Sacroiliac joints is a Lead Indicator of Radiographic Progression in the Spine of Patients with Ankylosing SpondylitisMaksymowych WP, Wichuk…
Abstract Number: 2993 • 2014 ACR/ARHP Annual Meeting
MRI in Neuropsychiatric Lupus: Correlations with the 1999 ACR Case Definitions
Minyoung Her¹, Dongyook Kim², Na young Park², Seong-Kyu Kim³, Lee Sung Won⁴ and Lee sang Yeob⁵, ¹Pusan Paik Hospital, Inje Univ, Inje University, Pusan Paik Hospital, Busan, South Korea, Busan, South Korea, ²Inje University, Pusan Paik Hospital, Busan, South Korea, Busan, South Korea, ³Devision of Rheumatology, Department of Internal Medicine, Arthritis & Autoimmunity Research Center, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁴Dong-A university,Busan, South Korea, Pusan, South Korea, ⁵Dong -A university, Dong-A university,Busan, South Korea, Pusan, South Korea
Background/Purpose: Neurological manifestations in SLE are diverse. Because of its varied manifestations and low prevalence, the ACR has developed nomenclature and case definitions for neuropsychiatric…
Abstract Number: 2661 • 2014 ACR/ARHP Annual Meeting
Serum Neuronal Biomarkers and Brain Atrophy in Childhood-Onset Systemic Lupus Erythematosus
Aline T. Lapa¹, Mariana Postal¹, Nailu A. Sinicato¹, Renata Barbosa², Fernando Cendes³, Roberto Marini⁴ and Simone Appenzeller⁵, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Medicine, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Germany, ³Neurology, State University of Campinas, Campinas, Brazil, ⁴Departament of Pediatrics, State University of Campinas, Campinas, Brazil, ⁵Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose We aimedto investigate the association of serum biomarkers and regional and diffuse brain atrophy in cSLE. Methods We included consecutive cSLE patients (disease-onset before…
Abstract Number: 2660 • 2014 ACR/ARHP Annual Meeting
Metabolic Syndrome Features Can Influenciate Cognitive Functions and Brain Lesions in Childhood-Onset Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Aline T. Lapa¹, Mariana Postal¹, Bruna Bellini¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³Departament of Pediatrics, State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: The underlying factor for an association between the metabolic syndrome (MetS) and cognitive decline might be a subclinical inflammation. Inflammatory mechanisms are hypothesized to…
Abstract Number: 2613 • 2014 ACR/ARHP Annual Meeting
Positive Spine MRI for Inflammation Predicts Radiographic Progression in Patients with Ankylosing Spondylitis
Walter P. Maksymowych¹, S Wichuk², Z Zhao³, P Chiowchanwisawakit⁴, RG Lambert⁵ and Sj Pedersen⁶, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³PLA General Hospital, Beijing, China, ⁴Mahidol University, Bangkok, Thailand, ⁵Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Inflammation at vertebral corners on MRI has been shown to predict development of syndesmophytes in patients with AS. However, it is unclear at a…
Abstract Number: 1183 • 2014 ACR/ARHP Annual Meeting
Validation of the Omeract Psoriatic Arthritis Magnetic Resonance Imaging Score for the Hand and Foot in a Randomized Placebo-Controlled Trial
Daniel Malm¹, P. Bird², Frédérique Gandjbakhch³, Philip J. Mease⁴, Pernille Bøyesen⁵, Mikkel Østergaard⁶, Charles G. Peterfy⁷ and Philip G. Conaghan⁸, ¹Center for Rheumatology and Spinal Diseases, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, ²Combined Rheumatology Practice, Sydney, Australia, ³Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, Paris, France, ⁴Swedish Medical Center and University of Washington, Seattle, WA, ⁵Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, ⁷Spire Sciences LLC, Boca Raton, FL, ⁸Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom
Background/Purpose The joint involvement in psoriatic arthritis (PsA) is heterogeneous, and inflammation is seen in both axial and peripheral joints, including the small joints of…
Abstract Number: 1174 • 2014 ACR/ARHP Annual Meeting
Evaluating MRI-Detected Tenosynovitis of the Hand and Wrist in Early Arthritis
W.P. Nieuwenhuis¹, A. Krabben¹, W. Stomp², T. W. J. Huizinga¹, D. M. van der Heijde¹, J.L Bloem², M. Reijnierse³ and A.H.M. van der Helm-van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands
Background/Purpose Magnetic resonance imaging (MRI) is a sensitive method to detect local inflammation in rheumatoid arthritis (RA), visualizing synovitis, bone marrow edema and tenosynovitis. The…
Abstract Number: 854 • 2014 ACR/ARHP Annual Meeting
Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy (SpA): A 48-Week Randomized Controlled Trial
Chi Chiu Mok¹, Angela Li², Kar Li Chan¹ and Ling Yin Ho¹, ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Radiology, Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose To compare the efficacy of golimumab(GLM) and pamidronate(PAM) in the treatment of SpA.Methods Inclusion criteria: (1) patients ≥18 years of age; (2) fulfills the…
Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting
Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative
Jeffrey B. Driban¹, Felix Liu², Alina O'Brien³, Lori Lyn Price⁴, Grace H. Lo⁵, Michael C. Nevitt⁶, Charles Eaton⁷, Timothy E. McAlindon⁸ and John A. Lynch⁹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²University of California at San Francisco, San Francisco, CA, ³Tufts Medical Center, Boston, MA, ⁴Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ⁶Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁷Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁸Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁹Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA
Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
Abstract Number: 829 • 2013 ACR/ARHP Annual Meeting
Is The Severity Of Knee Osteoarthritis On MRI Associated With Outcome Of Exercise Therapy?
Jesper Knoop¹, Joost Dekker², Marike van der Leeden^3,4, Martin van der Esch⁴, J.P. Klein⁵, David J. Hunter⁶, Leo D. Roorda⁴, Martijn P.M. Steultjens⁷ and Willem F. Lems⁸, ¹Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²Rehabilitation Medicine, Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, ³Rehabilitation Medicine/EMGO, VU University Medical Center, Amsterdam, Netherlands, ⁴Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁵Radiology, VU University Medical Center, Amsterdam, Netherlands, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, ⁸Rheumatology, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: To evaluate associations between severity of knee osteoarthritis (OA) on MRI and treatment outcome in knee OA patients treated with exercise therapy. Methods: Ninety-five…
Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting
Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla
Hitomi Kobayashi^1,2, Isamu Yokoe³, Hiroshi Sato², Yasuyuki Kobayashi⁴, Kihei Yoneyama⁵, Masaharu Hirano⁶ and Masami Takei⁷, ¹Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ³Nihon University School of Medicine, Tokyo, Japan, ⁴Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁵Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁶Cardiology, Tokyo Medical Colleage, Tokyo, Japan, ⁷Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan
Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
Abstract Number: 82 • 2013 ACR/ARHP Annual Meeting
Anatomical Variation In The Morphology Of The Posterior Cruciate Ligament Synovio-Entheseal Complex and Correlation With Degenerative Change
Daniel Binks¹, Diane Bergin², Tony Freemont³, Aleksandra Radjenovic¹ and Dennis McGonagle⁴, ¹NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ²Radiology, Galway University Hospitals, Galway, Ireland, ³School of Medicine, University of Manchester, Manchester, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Ligament attachments are often found to form complex anatomical functional units involving the ligaments themselves as well as associated synovium and bony tuberosities. Furthermore,…
Abstract Number: 151 • 2013 ACR/ARHP Annual Meeting
The mtDNA Haplogroups Influence The Cartilage Integrity In Osteoarthritis. Data From The Osteoarthritis Initiative (OAI)
Ignacio Rego-Pérez¹, Angel Soto-Hermida², Mercedes Fernández-Moreno², Sonia Pértega-Díaz³, Juan Fernández-Tajes², María Eugenia Vázquez-Mosquera², Estefanía Cortés-Pereira², Sara Relaño-Fernández², Natividad Oreiro-Villar², Carlos Fernández-López² and Francisco J. Blanco^4,5,6, ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, ³Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ⁴Osteoarticular and Aging Res. Lab. CIBER-BBN. INIBIC- University of A Coruña, A Coruña, Spain, ⁵Proteo-Red/ISCIII, Madrid, Spain, ⁶CIBER-BBN-ISCIII, Madrid, Spain
Background/Purpose: Magnetic resonance imaging (MRI) is ideally suited for detect structural changes and degradation in cartilage against the limitations of radiographic common methods. Changes in…
Abstract Number: 65 • 2013 ACR/ARHP Annual Meeting
The Frequency Of Bone Marrow Oedema Adjacent To The Cruciate Ligament Peri-Entheseal Vascular Channels In Inflammatory and Degenerative Arthritis
Daniel Binks^1,2, Melissa Matzelle³, Diane Bergin⁴, Richard J. Hodgson^2,5, Ai Lyn Tan^1,2, Ellen M. Gravallese⁶, Dennis McGonagle^1,2,7 and Aleksandra Radjenovic^1,2, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ³Department of Medicine, Division of Rheumatology, University of Massachusetts Medical School, Worcester, MA, ⁴Radiology, Galway University Hospitals, Galway, Ireland, ⁵NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁶Department of Medicine, Division of Rheumatology, UMass Memorial Medical Center, Worcester, MA, ⁷Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: We noted in mouse models of inflammatory arthritis (IA) that an early point of entry of inflammation into the marrow space occurred at sites…

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