Abstract Number: 1243 • 2012 ACR/ARHP Annual Meeting
Effect of Tocilizumab Treatment On Regional Left Ventricular Function, As Assessed by Cardiac Magnetic Resonance Imaging, in Rheumatoid Arthritis Patients without Cardiac Symptoms
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of congestive heart failure, possibly via shared mechanisms of inflammation. This study was undertaken to…Abstract Number: 802 • 2012 ACR/ARHP Annual Meeting
Milnacipran Reduces Brain Activity During Pain in Fibromyalgia
Background/Purpose: Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain and a number of concomitant symptoms such as fatigue, sleep disturbance, cognitive…Abstract Number: 1119 • 2012 ACR/ARHP Annual Meeting
Prediction of MRI-Detected Cartilage Loss Over 30 Months Using Simplified Radiographic and Clinical Stratification: The MOST Study
Background/Purpose: MRI-detected cartilage loss is the main structural outcome measure in large studies of knee OA. Definition of subjects at high risk for cartilage loss…Abstract Number: 805 • 2012 ACR/ARHP Annual Meeting
Milnacipran Increases Cortical to Brainstem Connectivity During Pain in Fibromyalgia
Background/Purpose: Fibromyalgia (FM) is a chronic widespread pain disorder characterized by muscle tenderness, fatigue, poor sleep, and mood disturbance. Milnacipran is a dual serotonin-norepinephrine reuptake…Abstract Number: 1124 • 2012 ACR/ARHP Annual Meeting
Total Knee Replacement As an Osteoarthritis Study Outcome: Predictors Derived From Long-Term Observation Following a Randomized Clinical Trial
Background/Purpose: Using data from a 4-year follow-up of knee OA patients who formerly received treatment with chondroitin sulfate (CS) within a 6-month clinical trial, we…Abstract Number: 806 • 2012 ACR/ARHP Annual Meeting
Posterior Insula Combined Glutamate and Glutamine Is Associated with Pain in Fibromyalgia: A Replication Study
Background/Purpose: Central pain augmentation resulting from enhanced excitatory and/or decreased inhibitory neurotransmission is a proposed mechanism underlying the pathophysiology of functional pain syndromes such as…Abstract Number: 1131 • 2012 ACR/ARHP Annual Meeting
Intraarticular Infliximab for Knee Osteoarthritis: High Baseline Levels of Synovial Cellularity and High MRI Cartilage Injury At the Lateral Tibial Plateau Predict Improvement in Total WOMAC Score
Background/Purpose: Synovial tissue from patients with OA often demonstrates inflammation. We hypothesized that a single intraarticular (IA) injection of an anti-TNF drug would decrease inflammatory…Abstract Number: 721 • 2012 ACR/ARHP Annual Meeting
Measurement of Pulmonary Arteries by Cardiac Magnetic Resonance Imaging: A Simple and Useful Tool for the Detection of Pulmonary Hypertension in Systemic Sclerosis Patients without Overt Cardiac Microvascular Perfusion Defects or Fibrosis
Background/Purpose: Pulmonary hypertension (PH) is a major complication of systemic sclerosis (SSc). We observed that a significant proportion of our SSc patients with PH as…Abstract Number: 2534 • 2012 ACR/ARHP Annual Meeting
The Intensive Diet and Exercise for Arthritis Trial (IDEA): 18-Month Radiographic and MRI Outcomes
Background/Purpose: Dietary induced weight loss is a proven non-pharmacologic intervention for osteoarthritis. Based upon current literature it is unclear if weight loss modifies structural progression.…Abstract Number: 1103 • 2012 ACR/ARHP Annual Meeting
Cumulative Occupational Physical Load As Risk Factor for Knee Osteoarthritis
Background/Purpose: Knee osteoarthritis (OA) results from the interaction of multiple risk factors, one of which may be physically demanding occupations. The purpose of this study…Abstract Number: 611 • 2012 ACR/ARHP Annual Meeting
Impaired Diffusion Tensor Imaging Findings in the Corpus Callosum and Cingulum May Underlie Impaired Learning and Memory Abilities in Systemic Lupus Erythematosus
Background/Purpose: Memory impairment is prevalent in systemic lupus erythematosus (SLE), however the pathogenesis is unknown. In a previous functional Magnetic Resonance Imaging (MRI) study we…Abstract Number: 2538 • 2012 ACR/ARHP Annual Meeting
The Association of Fat Mass and Skeletal Muscle Mass with Clinical and Structural Knee Osteoarthritis: The Netherlands Epidemiology of Obesity Study
Background/Purpose: Body mass index (BMI) is an important risk factor for knee osteoarthritis (OA), but BMI depends only upon height and weight and gives no…Abstract Number: 1111 • 2012 ACR/ARHP Annual Meeting
Erosive Evolution in Hand Osteoarthritis Is Associated with Incident Joint Tenderness Independent of MRI-Defined Bone Marrow Lesions and Synovitis
Background/Purpose: Previous studies have shown no association between increased amount of radiographic hand osteoarthritis (OA) resulting in more hand pain/disabilities. In this longitudinal study, our…Abstract Number: 571 • 2012 ACR/ARHP Annual Meeting
Description of Distribution of Active Inflammatory Lesions On Magnetic Resonance Imaging of the Sacroiliac Joints and the Spine in Patients with Early Axial Spondyloarthritis – Analysis of the Esther Trial Baseline Data
Background/Purpose: To address the question whether active inflammation starts at specific sites of the sacroiliac joints (SI-joints) and/ or the spine. Methods: Wb-MRIs of…Abstract Number: 2512 • 2012 ACR/ARHP Annual Meeting
Changes in Bone Marrow Lesion Volume Relate to Changes in Knee Pain. Data From the Osteoarthritis Initiative
Background/Purpose: Changes in bone marrow lesions (BMLs), common magnetic resonance (MR) imaging findings in osteoarthritis (OA), are predictive of OA progression. However, it is unclear…