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Abstracts tagged "magnetic resonance imaging (MRI) and rheumatoid arthritis (RA)"

  • Abstract Number: 308 • ACR/ARHP Annual Meeting 2018

    Carpal Bones Affectation Frequency in Rheumatoid Arthritis By Magnetic Resonance Imaging

    Maria Del Carmen Larios-Forte1, Cassandra Skinner-Taylor1, Dionicio A. Galarza-Delgado2, Jorge Esquivel-Valerio3, Janett Riega-Torres4, David Vega-Morales1 and Itzel Perez-Onofre5, 1Rheumatology, University Hospital “Dr. José Eleuterio González”, UANL, Monterrey, Mexico, 2Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 3Rheumatology, University Hospital “Dr. José Eleuterio González”, UANL, Mexico, Monterrey, Mexico, 4University Hospital “Dr. José Eleuterio González”, UANL, Monterrey, Mexico, 5Rheumatology, University Hospital “Dr. José Eleuterio González” U.A.N.L, Monterrey, Mexico

    Background/Purpose: Wrist joint between radio-ulna and first carpal row; scaphoid and triquetrum bones stabilize the central carpal column and support the flexion-extension or abduction-adduction movements1.…
  • Abstract Number: 870 • ACR/ARHP Annual Meeting 2017

    Detection of Left Ventricular Regional Function in Rheumatoid Arthritis Patients without Cardiac Symptons, As Assessed By Feature Tracking Cardiac Magnetic Resonance Imaging

    Hitomi Kobayashi1, Yasuyuki Kobayashi2, Isamu Yokoe3, Akiyuki Kotoku4, Atsuma Nishiwaki5, Kaita Sugiyama6, Noboru Kitamura5 and Masami Takei5, 1Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 3Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, 4Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, 5Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 6Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose: Cardiac involvements cause of morbidity and mortality globally in rheumatoid arthritis (RA). Myocardial disease is typically clinically silent, only manifesting as myocardial dysfunction after…
  • Abstract Number: 1992 • ACR/ARHP Annual Meeting 2017

    Changes in Clinical Disease Activity  Are Associated with Changes in the Total MRI Inflammation Score in Rheumatoid Arthritis Patients Who Are Escalating Therapy in a Treat-to-Target (T2T) Regimen

    Fiona M. McQueen1, Peter T. Chapman2, Terina Pollock3, Dena D'Souza4, Arier Lee5, Nicola Dalbeth6, Lisa K. Stamp7, Karen Lindsay8 and Anthony Doyle3,9, 1Molecular Medicine, Univ of Auckland Sch of Med, Auckland, New Zealand, 2Christchurch Hospital, Christchurch, New Zealand, 3Radiology, Auckland District Health Board, Auckland, New Zealand, 4Rheumatology, University of Auckland, Auckland, New Zealand, 5Biostatistics and Epidemiology, University of Auckland, Auckland, New Zealand, 6University of Auckland, Auckland, New Zealand, 7University of Otago, Christchurch, New Zealand, 8Rheumatology, Auckland District Health Board, Auckland, New Zealand, 9Anatomy with Radiology, University of Auckland, Auckland, New Zealand

    Background/Purpose: RA patients are managed using treat-to target (T2T) regimens often utilizing the DAS28CRP as an outcome measure. In this study we compared clinical changes…
  • Abstract Number: 1993 • ACR/ARHP Annual Meeting 2017

    Are MRI-Detected Erosions Specific for RA? a Large Explorative Cross-Sectional Study

    Debbie M. Boeters1, Wouter P. Nieuwenhuis1, Hanna W van Steenbergen1, M. Reijnierse2, Robert B.M. Landewé3 and Annette H.M. van der Helm-van Mil1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 3University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands

    Background/Purpose: Magnetic resonance imaging (MRI) is recommended in the diagnostic process of rheumatoid arthritis (RA), as it can detect joint damage early. However MRI-detected erosions…
  • Abstract Number: 9 • ACR/ARHP Annual Meeting 2016

    Effects of Alcohol Consumption on the Severity of Inflammation in Hand and Foot Joints Detected with MR Imaging

    L. Mangnus1, M. Reijnierse2 and A.H.M. van der Helm- van Mil3, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Moderate alcohol consumption is associated with a lower risk on RA development. (1,2) It is also associated with less severe systemic inflammation. Based on these…
  • Abstract Number: 167 • ACR/ARHP Annual Meeting 2016

    Bone Mineral Density Loss in Clinically Suspect Arthralgia Is Associated with Subclinical Inflammation and Progression to Clinical Arthritis

    L. Mangnus1, H.W. van Steenbergen2, M. Reijnierse3, J. Kälvesten4,5,6 and A.H.M. van der Helm-van Mil2, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands, 4Radiology, Faculty of Health Sciences, Linköping, Sweden, 5Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden, 6Sectra AB, Linköping, Sweden

    Background/Purpose: Peripheral bone mineral density (BMD) can be decreased in early rheumatoid arthritis but it is unknown if BMD loss emerges already before arthritis is…
  • Abstract Number: 515 • ACR/ARHP Annual Meeting 2016

    The Association of Body Mass Index with the Severity of  Magnetic Resonance Imaging-Detected Inflammation at Presentation; Opposite Effects in Early Rheumatoid Arthritis Compared to Other Arthritides and an Asymptomatic Population

    L. Mangnus1, W.P. Nieuwenhuis2, H.W. van Steenbergen2, T.W.J. Huizinga3, M. Reijnierse4 and A.H.M. van der Helm-van Mil2, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: An increased body mass index (BMI) has been associated with slightly increased inflammatory markers in the population. Within rheumatoid arthritis (RA) a high BMI…
  • Abstract Number: 2055 • ACR/ARHP Annual Meeting 2016

    Myocardial Abnormalities Are Associated with Corrected QT Interval in Patients with Rheumatoid Arthritis without Cardiac Symptoms Assessed Using Cardiac Magnetic Resonance Imaging

    Yasuyuki Kobayashi1, Hitomi Kobayashi2, Atsuma Nishiwaki3, Kaita Sugiyama3, Yosuke Nagasawa4, Takamasa Nozaki2, Noboru Kitamura5, Masami Takei4, Natsumi Ikumi6 and Hirotake Inomata3, 1Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 2Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Nihon University School of Medicine, Tokyo, Japan, 4Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 5Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan, 6Nihon University School of Medicine, Shinjuku, Japan

    Background/Purpose: Individuals with rheumatoid arthritis (RA) have two-fold higher risk of sudden death than age- and sex-matched controls without RA. We hypothesized that myocardial abnormalities…
  • Abstract Number: 1309 • ACR/ARHP Annual Meeting 2015

    Defining an Acceptable Level of MRI Inflammation in Rheumatoid Arthritis

    Joshua Baker1, Mikkel Østergaard2, Daniel Baker3, Paul Emery4 and Philip G. Conaghan5, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, 3Immunology, Centocor Inc., Malvern, PA, 4Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, 5University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom

    Background/Purpose: Imaging-detected inflammation persists in many rheumatoid arthritis (RA) patients despite therapy. We used data from two clinical trials of golimumab to determine thresholds for…
  • Abstract Number: 1316 • ACR/ARHP Annual Meeting 2015

    Is MRI of Use in Identifying Which Undifferentiated Arthritis Patients Will Develop RA?

    W.P. Nieuwenhuis1, E.C. Newsum1, H.W. van Steenbergen2, L. Mangnus1, T. W. J. Huizinga1, M. Reijnierse3 and A.H.M. van der Helm- van Mil2, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The 2010 ACR/EULAR criteria for rheumatoid arthritis (RA) identify RA patients earlier than the 1987 ACR criteria. However, still a considerable amount of patients…
  • Abstract Number: 1579 • ACR/ARHP Annual Meeting 2015

    Association of Myocardial Abnormalities with N-Terminal Pro-Brain Natriuretic Peptide and Disease Activity in Rheumatoid Arthritis without Cardiac Symptoms, Assessed By Cardiac Magnetic Resonance Imaging

    Hitomi Kobayashi1, Yasuyuki Kobayashi2, Isamu Yokoe3, Natsumi Ikumi4,5, Hirotake Inomata6, Atsuma Nishiwaki6, Noboru Kitamura1, Kaita Sugiyama6, Hidetake Shiraiwa6, Masataka Nozaki6, Yosuke Nagasawa6, Yoshihiro Matsukawa5 and Masami Takei1, 1Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 3Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, 4Nihon University School of Medicine, Shinjuku, Japan, 5Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 6Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is a multi-organ inflammatory disorder associated with high cardiovascular morbidity and mortality. Cardiac involvements are typically clinically silent, only manifesting as…
  • Abstract Number: 2586 • ACR/ARHP Annual Meeting 2015

    Cardiac Magnetic Resonance Imaging Reveals Myocardial Damage in Patients with Active Rheumatoid Arthritis

    Miia Holmström1, Riitta Koivuniemi2, Tarja Tiippana-Kinnunen2, Antti Kuuliala3, Marjatta Leirisalo-Repo2 and Sari Kivistö1, 1Radiology, HUS Medical Imaging Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, 2Rheumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, 3Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

    Background/Purpose: In rheumatoid arthritis (RA), cardiac involvement is common and frequently subclinical. We used cardiac MRI to identify myocardial abnormalities in patients with active RA,…
  • Abstract Number: 2389 • ACR/ARHP Annual Meeting 2014

    MRI Osteitis at Baseline Predicts the Development of Rapid Radiographic Progression at 1 Year Toward Patients with Early-Stage Rheumatoid Arthritis

    Yoshikazu Nakashima1, Mami Tamai2, Junko Kita3, Sousuke Tsuji1, Shoichi Fukui1, Masataka Umeda1, Ayako Nishino1, Takahisa Suzuki1, Yoshiro Horai1, Akitomo Okada4, Tomohiro Koga1, Shinya Kawashiri5, Naoki Iwamoto1, Kunihiro Ichinose1, Yasuko Hirai1, Kazuhiko Arima5, Hideki Nakamura1, Tomoki Origuchi6, Masataka Uetani7, Kiyoshi Aoyagi5, Katsumi Eguchi8 and Atsushi Kawakami1, 1Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 2Departments of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 3Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 4Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 5Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 6Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 8Sasebo City General Hospital, Sasebo, Japan

    Background/Purpose: EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis (RA) states that magnetic resonance imaging (MRI)…
  • Abstract Number: 1891 • ACR/ARHP Annual Meeting 2014

    Early MRI Endpoints Provide a Valid Measure of Structural Damage While Reducing Study Duration and Participant Numbers in Rheumatoid Arthritis Clinical Trials

    Joshua Baker1, Philip G. Conaghan2, Paul Emery3, Daniel Baker4 and Mikkel Østergaard5, 1Medicine/Rheumatology, Philadelphia VA Medical Center, Philadelphia, PA, 2University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 3NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Janseen R&D, Spring House, PA, 5Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark

    Background/Purpose We used data from a large randomized controlled clinical trial of an effective biologic (golimumab, GO-BEFORE study) to compare the associations of disease activity…
  • Abstract Number: 1381 • ACR/ARHP Annual Meeting 2014

    Subaxial Cervical Spine Involvement in Symptomatic Rheumatoid Arthritis Patients: Comparison with Cervical Spondylosis

    Helena Borrell1, Javier Narváez2, Jose Antonio Narvaez3, Marta Serrallonga4, Carmen Gomez Vaquero1, Eugenia de Lama5, Javier Hernandez Gañan3 and Joan Miquel Nolla1, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, 3Radiology Department, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, 4Institut de Diagnostic per la Imatge (IDI), Centre Bellvitge, Barcelona, Spain, 5Radiology, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: To investigate the frequency, location, nature, and clinical significance of subaxial involvement (below C1-C2) in a series of patients with rheumatoid arthritis (RA) and…
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