Abstracts tagged "magnetic resonance imaging (MRI) and osteoarthritis"

Abstract Number: 320 • 2018 ACR/ARHP Annual Meeting
Development of a Magnetic Resonance Imaging Atlas for the Classification of Osteoarthritis of the First Metatarsophalangeal Joint
Shannon Munteanu, Karl Landorf, Jade Tan, Maria Auhl, Jamie Allan, Andrew Buldt and Hylton B. Menz, School of Allied Health, La Trobe University, Bundoora, Australia
Background/Purpose: Osteoarthritis (OA) of the first metatarsophalangeal joint (MTPJ) of the foot is the most common form of foot OA. The condition is typically evaluated…
Abstract Number: 423 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Pre-Radiographic Degeneration of the Extensor Mechanism and Cruciate Ligaments: Data from the Osteoarthritis Initiative
Julie Davis¹, Matthew Harkey¹, Robert J. Ward², James MacKay³, Lori Lyn Price^4,5, Charles B. Eaton⁶, Grace H. Lo⁷, Mary Barbe⁸, Timothy E. McAlindon⁹ and Jeffrey B. Driban¹⁰, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Radiology, Tufts Medical Center, Boston, MA, ³Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁷Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ⁸Temple University School of Medicine, Philadelphia, PA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA, ¹⁰Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Degeneration of knee ligaments and tendons, which may be signs of joint instability and abnormal joint loading, may antedate the onset of radiographic accelerated…
Abstract Number: 1362 • 2018 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging Features Can Classify Adults Who Will Develop Accelerated Knee Osteoarthritis
Lori Lyn Price^1,2, Matthew Harkey³, Robert J. Ward⁴, James MacKay⁵, Ming Zhang⁶, Julie Davis⁷, Timothy E. McAlindon⁸, Grace H. Lo⁹, Mamta Amin¹⁰, Charles B. Eaton¹¹, Bing Lu¹², Jeffrey Duryea¹³, Mary Barbe¹⁴ and Jeffrey B. Driban¹⁵, ¹Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ²Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ³Rheumatology, Tufts Medical Center, Boston, MA, ⁴Radiology, Tufts Medical Center, Boston, MA, ⁵Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁶Tufts Medical Center, Boston, MA, ⁷Rheumatology, Tufts Medical Center, BOSTON, MA, ⁸Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ¹⁰Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, ¹¹Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ¹²Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ¹³Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ¹⁴Temple University School of Medicine, Philadelphia, PA, ¹⁵Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Accelerated knee osteoarthritis (AKOA) is a painful disorder and is associated with several risk factors and pre-radiographic structural features. While no single factor can…
Abstract Number: 1208 • 2017 ACR/ARHP Annual Meeting
Levels of Serum Biomarkers from a Two-Year Multicentre Trial Are Associated with Treatment Response on Knee Osteoarthritis Cartilage Loss As Assessed By MRI: An Exploratory Study
Johanne Martel-Pelletier¹, Jean-Pierre Raynauld¹, François Mineau¹, François Abram², Patrice Paiement³, Philippe Delorme³ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³ArthroLab Inc., Montreal, QC, Canada
Background/Purpose: There is an obvious need to identify biomarkers that could predict patient response to an osteoarthritis (OA) treatment. This post hoc study explored in…
Abstract Number: 2344 • 2016 ACR/ARHP Annual Meeting
Inflammation and Glucose Homeostasis Are Associated with Specific Structural Features Among Adults without Knee Osteoarthritis
Alina Stout¹, Mary Barbe², Charles B. Eaton³, Mamta Amin⁴, Fatimah Al Eid¹, Lori Lyn Price⁵, Bing Lu⁶, Grace H. Lo⁷, Ming Zhang⁸, Timothy E. McAlindon⁹ and Jeffrey Driban⁸, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Temple University School of Medicine, Philadelphia, PA, ³Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁴Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, ⁵Clinical Care Research, Tufts Medical Center, Boston, MA, ⁶Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁷Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ⁸Tufts Medical Center, Boston, MA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Adults with osteoarthritis (OA) have greater glucose concentrations and inflammation. It remains unclear if inflammation and glucose homeostasis are related to specific features of…
Abstract Number: 2393 • 2015 ACR/ARHP Annual Meeting
Validation of a Web-Based Overlay for Sectoral Scoring of Active Lesions on MRI in Hip Osteoarthritis: Femoral Bone Marrow Lesions Predict Response to Intra-Articular Hyaluronate
Damien Loeuille¹, Nicolas Deseyne², Jacob Jaremko³, Ulrich Weber⁴, Thierry Conrozier⁵, Joel Paschke⁶, Walter Maksymowych⁷, Bernard Maillet⁸ and Henri Lellouche⁹, ¹Rheumatology, Department of Rheumatology, CHRU Vandoeuvre les Nancy, Vandoeuvre les Nancy, France, ²Department of Rheumatology, CHRU Vandoeuvre les Nancy,, Vandoeuvre, France, ³Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵Service de Rhumatologie,CHU de NANCY- Brabois, Vandoeuvre, France, ⁶CaRE Arthritis, Edmonton, AB, Canada, ⁷Medicine, University of Alberta, Edmonton, AB, Canada, ⁸Rheumatology, Clinique Saint Odilon, Moulins, France, ⁹Rheumatology, Hôpital Lariboisière, Paris, France
Background/Purpose: Bone marrow lesions (BML) and synovitis are MRI features that have been associated with symptoms and disease progression in patients with osteoarthritis. The Hip…
Abstract Number: 218 • 2014 ACR/ARHP Annual Meeting
Surface Area and Fatty Infiltration of Vastus Medialis Measured By Magnetic Resonance Imaging Are Risk Factors for the Progression of Knee Osteoarthritis and Discriminate Two Osteoarthritis Phenotypes
Johanne Martel-Pelletier¹, Jean-Pierre Raynauld¹, François Abram², Marc Dorais³, Yuanyuan Wang⁴, Jessica Fairley⁴, Flavia Cicuttini⁴ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada, ⁴Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Osteoarthritis (OA) is the most common arthritic condition but its treatment still remains symptomatic. Understanding factors affecting the progression of this disease may enable…
Abstract Number: 2669 • 2013 ACR/ARHP Annual Meeting
Treatment Of Knee Osteoarthritis Patients With Strontium Ranelate Reduces The Loss Of Cartilage Volume and Bone Marrow Lesions As Assessed By Magnetic Resonance Imaging: Data From The Phase III Strontium Ranelate Efficacy In Knee Osteoarthrtis Trial
Johanne Martel-Pelletier¹, Camille Roubille¹, Jean-Pierre Raynauld¹, François Abram², Marc Dorais³, Philippe Delorme¹ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada
Background/Purpose: This study aimed to evaluate in a subpopulation of osteoarthritis (OA) patients from the SEKOIA Phase III trial the disease-modifying (DMOAD) effect of strontium…
Abstract Number: 2670 • 2013 ACR/ARHP Annual Meeting
Does Change In Femorotibial Cartilage Thickness Differ Between Acutely Anterior-Cruciate Ligament Injured Knees Treated With and Without Reconstructive Surgery
Wolfgang Wirth¹, Felix Eckstein¹, Martin Hudelmaier², Stefan Lohmander³ and Richard Frobell⁴, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Paracelsus Medical University, Salzburg, Austria, ³Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ⁴Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: An ACL tear is a serious knee injury, involving chronic alterations in joint biomechanics. The risk of developing knee OA after an ACL tear…
Abstract Number: 2145 • 2013 ACR/ARHP Annual Meeting
Impact On Cartilage Volume Changes Over Time Of Conventional Treatment and Of Glucosamine and Chondroitin Sulfate In Knee Osteoarthritis Patients: Data From The Osteoarthritis Initiative Cohort
Johanne Martel-Pelletier¹, Camille Roubille¹, Jean-Pierre Raynauld¹, François Abram², Pierre Dodin³, Marc Dorais⁴, Philippe Delorme¹ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ⁴StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada
Background/Purpose: To explore, using data from participants enrolled in the progression cohort of the Osteoarthritis Initiative (OAI), the effects of conventional knee osteoarthritis (OA) pharmacological…
Abstract Number: 1136 • 2013 ACR/ARHP Annual Meeting
MR T1ρ and T2 Of Meniscus After Acute Anterior Cruciate Ligament Injuries
Elijah Abramson¹, Michael Hoppe², Toran MacLeod¹, Lorenzo Nardo¹, Julien Rivoire², Richard Souza¹, Thomas M Link³, C. Benjamin Ma⁴ and Xiaojuan Li³, ¹University of California, San Francisco, San Francisco, CA, ²Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ³Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁴Department of Orthopedic Surgery, UCSF, San Francisco, CA
Background/Purpose: Acute anterior cruciate ligament (ACL) injuries are high-risk factors for post-traumatic osteoarthritis. Cartilage changes in such cases have been widely studied; however, there are…
Abstract Number: 238 • 2013 ACR/ARHP Annual Meeting
Structural Predictors Of Ten Year Knee Cartilage Volume Loss
Dawn Aitken¹, Hussain Ijaz Khan¹, Changhai Ding², Leigh Blizzard³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicuttini⁵ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia
Background/Purpose: Cartilage volume loss is considered a key feature of knee osteoarthritis (OA) and increased loss over two years is associated with future knee replacement…
Abstract Number: 38 • 2012 ACR/ARHP Annual Meeting
Bone Marrow Lesions On Magnetic Resonance Imaging Are Not Associated with Regions of Hypermetabolism in an Animal Model of Osteoarthritis
Arash Panahifar¹, Jacob Jaremko², Robert GW Lambert², Walter P. Maksymowych³ and Michael R. Doschak¹, ¹Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada, ²Radiology, University of Alberta, Edmonton, AB, Canada, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The underlying histopathological basis for bone marrow lesions (BML) on magnetic resonance imaging (MRI) in osteoarthritis (OA) is unclear, but may be associated with…
Abstract Number: 2467 • 2012 ACR/ARHP Annual Meeting
Tissue Lesions in Osteoarthritis Initiative Participants with Normal X-Rays and Risk Factors for Incident Cartilage Damage
Leena Sharma¹, Ali Guermazi², Orit Almagor¹, Michel Crema², Dorothy D. Dunlop³, Frank Roemer⁴, Marc C. Hochberg⁵, Charles Eaton⁶, Joan M. Bathon⁷, Rebecca D. Jackson⁸, W.J. Mysiw⁸, C. Kent Kwoh⁹, Michael C. Nevitt¹⁰ and Joan S. Chmiel¹, ¹Northwestern University, Chicago, IL, ²Boston University, Boston, MA, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Klinikum Augsburg, Augsburg, Germany, ⁵Department of Medicine, University of Maryland, Baltimore, MD, ⁶Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁷Columbia University, New York, NY, ⁸Ohio State University, Columbus, OH, ⁹School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹⁰Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA
Background/Purpose: Understanding factors underlying initial development of knee OA is crucial to effective prevention strategy design. Our goals were to: 1) determine extent of tissue…
Abstract Number: 1117 • 2012 ACR/ARHP Annual Meeting
Association Between Hip Bone Marrow Lesions (BMLs) and Bone Mineral Density: A Cross-Sectional and Longitudinal Population-Based Study
Harbeer Ahedi¹, Dawn Dore¹, Leigh Blizzard², Flavia Cicuttini³ and Graeme Jones⁴, ¹Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ³Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia, ⁴Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Bone marrow lesions (BMLs) have been identified one of the key pathologic features in knee osteoarthritis (OA) 1. However, there is limited data on…

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