ACR Meeting Abstracts

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Abstracts tagged "macrophages and rheumatoid arthritis"

  • Abstract Number: 178 • 2016 ACR/ARHP Annual Meeting

    Alpha-Enolase Promotes Pro-Inflammatory Phenotype of Monocytes-Derived Macrophages

    Pascal Rottenberg1,2, Manuel Fréret1,2, Sébastien Calbo1 and Olivier Vittecoq1,2, 1INSERM U905 & Normandy University, Institute for Research and Innovation in Biomedicine, Rouen, France, 2Rheumatology, Rouen University Hospital, Rouen, France

    Background/Purpose:  Monocytes of healthy donors were cultured with M-CSF (gcultured with ENO1, or control BSA, to investigate its effect on monocytes differentiation and macrophages polarization.…
  • Abstract Number: 2905 • 2014 ACR/ARHP Annual Meeting

    The IL-6/Th17 Axis Promotes Autoantibody-Associated Autoimmune Valvular Carditis in Mice

    Jennifer L. Auger1, Brianna J. Engelson2, Yaya Wang3, Erik J. Peterson4 and Bryce A. Binstadt5, 1Center for Immunology and Department of Pediatrics, University of Minnesota, Minneapolis, MN, 2Pediatrics, University of Minnesota, Minneapolis, MN, 3Medicine, University of Minnesota, Minneapolis, MN, 4University of Minnesota, Minneapolis, MN, 5Pediatric Rheumatology, University of Minnesota, Minneapolis, MN

    Background/Purpose: Autoimmune valvular carditis occurs in patients with systemic lupus erythematosus, rheumatoid arthritis and rheumatic fever, but the pathogenic mechanisms remain incompletely defined. Spontaneous autoimmune…
  • Abstract Number: 343 • 2014 ACR/ARHP Annual Meeting

    The Caspase 8/RIPK3 Signaling Axis Has Opposing Roles in Myeloid and Dendritic Cells during Progression of a Murine Model of Acute Inflammatory Arthritis

    Carla M. Cuda1, Alexander Misharin2, George Kenneth Haines III3 and Harris R. Perlman4, 1Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Chicago, IL, 3Pathology, The Mount Sinai Hospital, New York, NY, 4Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose Rheumatoid arthritis (RA) manifests in persistent synovial inflammation, cellular infiltration and pro-inflammatory cytokine production, and results in progressive joint destruction.  Both myeloid cells and…
  • Abstract Number: 2524 • 2012 ACR/ARHP Annual Meeting

    Snapin Is Critical for the Maturation of Autophagosome and Phagosome in Macrophages

    Bo Shi1, Qiquan Huang2, Robert Birkett1, Renee E. Koessler3, Andrea Dorfleutner4, Christian Stehlik4 and Richard M. Pope5, 1Division of Rheumatology, Department od Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, 4Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose:  We found that Snapin, a SNARE complex protein required for synaptic vesicle docking and fusion, was significantly increased in rheumatoid arthritis (RA) synovial tissue…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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