Abstracts tagged "Macrophage"

Abstract Number: 2235 • 2013 ACR/ARHP Annual Meeting
Fas Signaling In Macrophages Promotes Chronicity In K/BxN Serum Transfer Induced Arthritis
Qi Quan Huang¹, Robert Birkett², Renee E. Koessler¹, Carla M. Cuda³, J.-P. Jin⁴, Harris R. Perlman⁵ and Richard M. Pope⁶, ¹Medicine/Rheumatology, Northwestern University, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, ³Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Physiology, Wayne State University, Detroit, MI, ⁵Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL
Background/Purpose: A non-apoptotic role for Fas signaling has been implicated in the regulation of inflammation and innate immunity. These studies were performed to elucidate the…
Abstract Number: 1764 • 2013 ACR/ARHP Annual Meeting
Binding Of Apoptotic Fetal Cardiocytes By Anti-Ro Antibodies Stimulates uPA/uPAR- Dependent Macrophage Infiltration and M2 Type Phenotype
Paraskevi Briasouli¹, Savvas Pavlides², Leslie Gold³, Mark Halushka⁴ and Jill P. Buyon⁵, ¹Rheumatology, New York University Medical Center, New York, NY, ²New York University Medical Center, new York, NY, ³new York University Medical Center, new York, NY, ⁴Division of Cardiovascular Pathology, John Hopkins Pathology, Baltimore, MD, ⁵Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY
Background/Purpose: Organ injury induced by antibodies characteristic of Sjogren's Syndrome and Systemic Lupus Erythematosus, while varied in the adult and fetus, may share in common…
Abstract Number: 1730 • 2013 ACR/ARHP Annual Meeting
Novel Role For Ly6C^– Monocyte Subsets and Joint Macrophages In Mouse Model Of Rheumatoid Arthritis
Alexander Misharin¹, Carla M. Cuda², Rana Saber³, Angelica K. Gierut⁴, G. Kenneth Haines III⁵, Steffen Jung⁶ and Harris R. Perlman⁷, ¹Medicine, Division of Rheumatology, Northwestern University, Chicago, IL, ²Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Medicine/Rheumatology, Northwestern University, Chicago, IL, ⁴Rheumatology, Northwestern Med Faculty Found, Chicago, IL, ⁵Department of Pathology, Yale University, New Haven, CT, ⁶Immunology, Weizmann Institute, Rehovot, Israel, ⁷Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Monocytes and macrophages play a key role in the pathogenesis of rheumatoid arthritis. However, role of the individual subsets of monocytes and macrophages in…
Abstract Number: 1279 • 2013 ACR/ARHP Annual Meeting
Anti-IL-6 Receptor Antibody Is Effective In Arthritis Regardless Of Obesity In Mouse Model
Miho Suzuki, Hiroto Yoshida and Yoshihiro Matsumoto, Product Research Department, Chugai Pharmaceutical Co., Ltd., Gotemba, Japan
Background/Purpose: Compared with non-obese patients, obese patients with rheumatoid arthritis (RA) reportedly experience worsening of symptoms [Arthritis Care Res (Hoboken). 2013; 65: 78-87] and do…
Abstract Number: 1159 • 2013 ACR/ARHP Annual Meeting
Exercise Suppresses Systemic Inflammation Via Inhibition Of NF-κB Activation In Monocytes
Alisa Blazek¹, Derrick Knapik², Lai-Chu Wu³, Nicholas A. Young³, Wael N. Jarjour⁴ and Sudha Agarwal⁵, ¹Molecular, Cellular and Developmental Biology, The Ohio State University, Columbus, OH, ²College of Medicine, The Ohio State University, Columbus, OH, ³Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁴Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Division of Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: Inflammation is integral to joint damage and bone erosion in rheumatoid arthritis. We reported previously that physiologic levels of exercise are anti-inflammatory and suppress local…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].