Abstracts tagged "Lymph node"

Abstract Number: 938 • 2018 ACR/ARHP Annual Meeting
Dermal Lymphatic Dysfunction and Photosensitivity in the MRL/Lpr Lupus Model
Noa Schwartz¹, Susan Chyou², Thomas Li³, William D. Shipman^2,4,5 and Theresa T. Lu³, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY, ³Hospital for Special Surgery, New York, NY, ⁴Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, ⁵Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY
Background/Purpose: Proper function of lymphatic vessels is needed to limit the magnitude and duration of tissue inflammation. Chronic inflammatory states such as obesity and psoriasis…
Abstract Number: 993 • 2018 ACR/ARHP Annual Meeting
Elucidating the Role of the Lymphatic System in the Pathogenesis of Psoriasis and Psoriatic Arthritis
H. den Braanker^1,2, A Otten-Mus³, P Asmawidjaja⁴, N Davelaar⁵, A.A.E.A. de Smet⁶, G.P. Akkersdijk⁶, B. Fioole⁶, J.B. Jaquet⁷, A. Hofman⁸, O.P. Schuitema⁸, Sander W. Tas⁹, R. Mebius¹⁰, Erik Lubberts⁴, M.R. Kok¹¹ and R.J. Bisoendial¹¹, ¹Rheumatology, Maasstad hospital, Rotterdam, Netherlands, ²Immunology and Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ³Rheumatology and Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁴Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁵Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁶Vascular surgery, Maasstad hospital, Rotterdam, Netherlands, ⁷Maasstad hospital, Rotterdam, Netherlands, ⁸Plastic Surgery, Maasstad hospital, Rotterdam, Netherlands, ⁹Clinical Immunology & Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ¹⁰Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, Netherlands, ¹¹Clinical Immunology and Rheumatology, Maasstad hospital, Rotterdam, Netherlands
Background/Purpose: Psoriasis is a common T-cell driven inflammatory skin disorder that is featured by immune cell infiltration, and vasculopathy of both blood and lymphatic vasculature.…
Abstract Number: 1431 • 2018 ACR/ARHP Annual Meeting
Kikuchi-Fujimoto Disease: A Retrospective Analysis of 23 Pediatric Cases from a US Center
Ekemini Ogbu^1,2, Shanmuganathan Chandrakasan^1,2, Sunita Park^1,2 and Sampath Prahalad^1,2, ¹Pediatrics, Emory University, Atlanta, GA, ²Children's Healthcare of Atlanta, Atlanta, GA
Background/Purpose: Kikuchi-Fujimoto Disease (KFD) is often described as a benign self-limited disease. However, there is a risk of recurrence. It is most common in adult…
Abstract Number: 1447 • 2018 ACR/ARHP Annual Meeting
Decreased Lymphatic Drainage in the Hands of Flaring RA Patients As Measured By Indocyanine Green Clearance Via Real Time Near Infrared Imaging
Richard Bell¹, Homaira Rahimi², Alicia Lieberman³, Ronald Wood⁴, Edward Schwarz⁵ and Christopher T. Ritchlin⁶, ¹Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ²Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY, ³Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁴University of Rochester, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY, ⁶Division of Allergy/Immunology and Rheumatology and Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester Medical School, Rochester, New York, USA, Rochester, NY
Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis established abnormal lymphatic vessel (LV) function during arthritic…
Abstract Number: 1776 • 2015 ACR/ARHP Annual Meeting
Significantly Reduced Lymphadenopathy, Salivary Gland Infiltrates and Proteinuria in MRL-Lpr/Lpr Mice Treated with Ultrasoluble Curcumin/Turmeric: Increased Survival with Curcumin Treatment
Biji T Kurien^1,2,3, Valerie M Harris^1,4, Syed MS Quadri^1,4, Patricia Coutinho-de Souza¹, Joshua Cavett^5,6, Amanda Moyer⁴, Bilal Ittiq⁷, Angela Metcalf⁶, Husayn Ramji⁸, Dat Truong⁸, Kristi A. Koelsch^4,9,10, Mike Centola¹¹, Adam Payne¹², D. Danda¹³ and R. Hal Scofield^1,14, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²U.S. Department of Veterans Affairs Medical Center, Oklahoma City, OK, ³College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁵Allergy and Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁷University of Oklahoma Health Sciences Center, Oklahoma, OK, ⁸University of Oklahoma, Oklahoma City, OK, ⁹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Okalahoma City, OK, ¹⁰Department Veterans Affairs Medical Center, Oklahoma City, OK, ¹¹Haus Bioceuticals, Oklahoma City, OK, ¹²Arthritis and Immunology, Oklahoma Medical Research Foun, Oklahoma City, OK, ¹³Christian Medical College, Vellore, India, ¹⁴US Department of Veterans Affairs Medical Center, Oklahoma City, OK
Background/Purpose: Commercial curcumin (CU), derived from food spice turmeric, has been widely studied as a potential therapeutic for a variety of oncological and inflammatory conditions.…
Abstract Number: 2621 • 2015 ACR/ARHP Annual Meeting
Characteristics of Histopathology and Clinical Course of 19 Cases That Developed a Lymphoproliferative Disease (LPD) during Methotrexate (MTX) Treatment.
Noriyuki HAYASHI¹, Kae HAMAMOTO², Kouichiro YODA², Maki YODA², Shinsuke YAMADA³, Hitoshi GOTO² and Masaaki INABA², ¹Rheumatology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan, ³Rheumatology, Osaka City University Graduate School of Midicine, Osaka, Japan
Background/Purpose: We examined the clinical features of the cases after discontinuation or decrease of dosage of MTX in the MTX-LPD.Methods: We retrospectively examined a patient…
Abstract Number: 2353 • 2014 ACR/ARHP Annual Meeting
The Nitric Oxide Receptor Soluble Guanylyl Cyclase Is Found in Lymphatic Vessels of Arthritic Mice and Inhibition Alters Lymphatic Pulse
Homaira Rahimi¹, Yawen Ju², Echoe M. Bouta³, Ronald Wood⁴, Christopher T. Ritchlin⁵ and Edward M. Schwarz⁶, ¹Rheumatology, University of Rochester/Golisano Children's Hospit, Rochester, NY, ²Univ of Rochester Med Ctr, University of Rochester, Rochester, NY, ³University of Rochester School of Medicine and Dentistry, Rochester, NY, ⁴Department of Urology, University of Rochester Medical Center, Rochester, NY, ⁵Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁶Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic erosive inflammatory condition that is characterized by episodes of “flare” due to synovitis of an affected joint. It…
Abstract Number: 934 • 2014 ACR/ARHP Annual Meeting
Amelioration of Inflammatory Arthritis By Anti-TNF Therapy Is Associated with Restoration of Lymphatic Contraction
Echoe M. Bouta¹, Igor Kuzin², Karen de Mesy-Bentley¹, Ronald Wood³, Homaira Rahimi⁴, Rui-Cheng Ji⁵, Christopher T. Ritchlin⁶, Andrea Bottaro², Lianping Xing⁷ and Edward M. Schwarz⁸, ¹University of Rochester, Rochester, NY, ²Cooper Medical School, Camden, NJ, ³Department of Urology, University of Rochester Medical Center, Rochester, NY, ⁴Rheumatology, University of Rochester/Golisano Children's Hospit, Rochester, NY, ⁵Department of Anatomy, Biology and Medicine, Oita University, Oita, Japan, ⁶Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁷Pathology & Lab Medicine, University of Rochester, Rochester, NY, ⁸Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with episodic flares. In tumor necrosis factor transgenic (TNF-Tg) mice, a model of inflammatory-erosive arthritis,…
Abstract Number: 1978 • 2013 ACR/ARHP Annual Meeting
The Effect Of Certolizumab On Lymphatic Volume and Flow In Rheumatoid Arthritis Patients With Acute Flare
Homaira Rahimi¹, Vaseem Chengazi², Gregory Dieudonne², Edward M. Schwarz³ and Christopher T. Ritchlin⁴, ¹Pediatrics, University of Rochester, Rochester, NY, ²Radiology, University of Rochester, Rochester, NY, ³Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ⁴Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY
Background/Purpose: Episodic flare occurs in rheumatoid arthritis (RA) but the mechanisms of this process are not well understood. Our prior reports on MRI analysis of…
Abstract Number: 1383 • 2013 ACR/ARHP Annual Meeting
Validation Of Popliteal Lymph Node Phenotype and Bin Expansion As Biomarkers Of Rheumatoid Arthritis Knee Flare
Homaira Rahimi¹, Ronald Wood², Igor Kuzin³, Wakenda Tyler⁴, Gregory Dieudonne⁵, Stephen Kates⁶, Christopher T. Ritchlin³ and Edward M. Schwarz⁷, ¹Pediatrics, University of Rochester, Rochester, NY, ²Department of Urology, University of Rochester Medical Center, Rochester, NY, ³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁴Orthopedics, University of Rochester, Rochester, NY, ⁵Radiology, University of Rochester, Rochester, NY, ⁶Orthopedic Surgery, University of Rochester Medical Center, Rochester, NY, ⁷Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Factors precipitating joint flare in rheumatoid arthritis (RA) patients are poorly understood. Contrast enhanced (CE) MRI studies in murine models have identified popliteal lymph…
Abstract Number: 198 • 2012 ACR/ARHP Annual Meeting
Diagnostic Predictors and Clinical Outcomes in Patients Presenting Solely with Lymphadenopathy
Huifang Lu, Xerxes Pundole and Khanh Vu, General Internal Medicine, UT MD Anderson Cancer Center, Houston, TX
Background/Purpose: Patients presenting solely with radiologic evidence of lymphadenopathy (LAD) to tertiary cancer centers are often diagnosed with malignancy or autoimmune diseases such as sarcoidosis.…
Abstract Number: 132 • 2012 ACR/ARHP Annual Meeting
FDG-PET Evaluation of Axillary Lymph Nodes and Large Joints of Patients with Rheumatoid Arthritis Treated with Anti-TNF Drugs
Koichi Okamura¹, Yukio Yonemoto², Tetsuya Kaneko³, Kimihiko Takeuchi⁴, Tsutomu Kobayashi¹ and Kenji Takagishi¹, ¹Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan, ²Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan, ³Department of Orthopaedic Surgery, Inoue Hospital, Takasaki, Gunma, Japan, ⁴Department of Rheumatology, Isesaki Fukushima Hospital, Isesaki, Gunma, Japan
Background/Purpose: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) can be used to image synovial inflammation in patients with rheumatoid arthritis (RA). The development of molecular…

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