Abstracts tagged "lymph node and rheumatoid arthritis (RA)"

Abstract Number: 51 • 2018 ACR/ARHP Annual Meeting
Genetic Ablation of Inducible Nitric Oxide Synthase in TNF Transgenic Mice with Inflammatory-Erosive Arthritis Prevents Lymph Node Expansion and Decreases Synovial Infiltrates
Richard Bell¹, Emily Wu², Lianping Xing³, Christopher T. Ritchlin⁴ and Edward Schwarz⁵, ¹Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ²Department of Immunology, Microbiology, and Virology, University of Rochester, Rochester, NY, ³University of Rochester Medical Center, Rochester, NY, ⁴Division of Allergy/Immunology and Rheumatology and Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester Medical School, Rochester, New York, USA, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY
Background/Purpose: Recent studies in the TNF-Tg mouse model of rheumatoid arthritis (RA) demonstrated a critical role of lymphatic vessel (LV) function in joint homeostasis and…
Abstract Number: 325 • 2014 ACR/ARHP Annual Meeting
Tadalafil Decreases Joint Inflammation in TNF-Tg Mice By Restoring Passive Lymphatic Transport
Echoe M. Bouta¹, Igor Kuzin², Ronald Wood³, Christopher T. Ritchlin⁴, Andrea Bottaro² and Edward M. Schwarz⁵, ¹University of Rochester, Rochester, NY, ²Cooper Medical School, Camden, NJ, ³Department of Urology, University of Rochester Medical Center, Rochester, NY, ⁴Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with enigmatic episodic flares. Using longitudinal imaging, we recently demonstrated that arthritic knee flare in…
Abstract Number: 333 • 2012 ACR/ARHP Annual Meeting
Pressure and Blood Flow Measurements in Efferent Lymphatics As Biomarkers of Arthritic Flare
Echoe M. Bouta¹, Ronald Wood², Christopher T. Ritchlin³, Lianping Xing⁴ and Edward M. Schwarz⁵, ¹University of Rochester, Rochester, NY, ²Department of Urology, University of Rochester School of Medicine and Dentistry, Rochester, NY, ³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁴Pathology & Lab Medicine, University of Rochester, Rochester, NY, ⁵Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic disease with episodic flares in affected joints. These flares are associated with decreased lymphatic drainage. In TNF-Tg mice,…