Abstracts tagged "Lupus"

Abstract Number: 2557 • 2013 ACR/ARHP Annual Meeting
Fluctuations In sVCAM-1 and Adiponectin Mirror Fluctuations In Disease Activity In Lupus, But Cannot Be Use To Accurately Predict Impending Changes In Disease State
Carolina landolt-Marticorena¹, Stephenie Prokopec², Stacey Morrison³, Heather Reich⁴, James Scholey⁴, Dafna D. Gladman⁵, Murray B. Urowitz⁵, Paul Boutros², Paul R. Fortin⁶ and Joan E. Wither⁷, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Ontario Institute for Cancer Research, Toronto, ON, Canada, ³Div Rheumatology Rm MP-10-304, The Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Medicine, The Toronto Western Hospital, Toronto, ON, Canada, ⁵Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶University of Laval, Quebec, QC, Canada, ⁷1E420/Div of Rheumatology, Toronto Western Research Institute, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Previous reports have identified a number of pro-inflammatory cyto/chemokines as candidate activity-specific SLE biomarkers. In our preliminary studies we found that out of a…
Abstract Number: 1261 • 2013 ACR/ARHP Annual Meeting
The Usefulness Of Traditional Neurocognitive Testing and N-Methyl-D-Aspartate Receptor Antibodies In Pediatric Lupus Patients
Natasha M. Ruth¹, Mary C. Kral², Tamara K. Nowling³, Stephanie Slan⁴, Murray H. Passo⁵ and Gary S. Gilkeson⁴, ¹Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ²Genetics and Developmental Pediatrics, MUSC, Charleston, SC, ³Medicine/Rheumatology, Medical University of South Carolina and Ralph H. Johnson VA Medical Center, Charleston, SC, ⁴Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ⁵Pediatrics, Medical University of South Carolina, Charleston, SC
Background/Purpose: In order to identify lupus patients at risk for CNS disease, and specifically, cognitive dysfunction, the ACR recommended a standard battery of tests for…
Abstract Number: 600 • 2013 ACR/ARHP Annual Meeting
Factors Associated With Long-Term Renal Function Deterioration In Lupus Nephritis Treated Initially With Combined Prednisolone and Mycophenolate Mofetil (MMF) Or Tacrolimus (Tac)
Chi Chiu Mok¹, Chi Hung To¹, King Yee Ying², Cheuk-Wan Yim³ and Woon Leung Ng⁴, ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Department of Medicine, Princess Margaret Hospital, Hong Kong, Hong Kong, ³Dept of Medicine, United Christian Hospital, Hong Kong, Hong Kong, ⁴Medicine, United Christian Hospital, Hong Kong, Hong Kong
Background/Purpose: To study the risk factors for renal function decline in patients with lupus nephritis treated initially with combined steroid and MMF or Tac.Methods: Data…
Abstract Number: 2539 • 2013 ACR/ARHP Annual Meeting
The Reliability Of a Novel Automated System For ANA Immunofluorescence Analysis In Daily Clinical Practice
Mohammed Alsuwaidi¹, Margit Dollinger¹, Martin Fleck^1,2 and Boris P. Ehrenstein¹, ¹Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ²Internal Medicine I, University Medical Center of Regensburg, Regensburg, Germany
Background/Purpose: Recently, automated interpretation (AI) systems for anti-nuclear antibody (ANA) analysis have been introduced based on assessment of indirect immunofluorescence (IIF) patterns. However, the reliability…
Abstract Number: 1063 • 2013 ACR/ARHP Annual Meeting
The Influence Of Socioeconomic and Race In Damage Score In Patients With Systemic Lupus Erythematosus
Roberto Teixeira¹, Eduardo F. Borba², Georges Christopoulos Sr.³ and Emilia Sato⁴, ¹UNIVERSIDADE FEDERAL DE SÃO PAULO, SAO PAULO, Brazil, ²Rheumatology Division; University of São Paulo, São Paulo, Brazil, ³SANTA CASA DE MISERICORDIA DE MACEIO, MACEIO, Brazil, ⁴Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: The association between socioeconomic status and damage in Systemic lupus erythematosus patients is confounded by the influence of race in various previous studies. The…
Abstract Number: 564 • 2013 ACR/ARHP Annual Meeting
Role of TLR3 and dsRNA Hyper-Responsiveness in the Generation of the Lupus-Like Phenotype of New Zealand Black Congenic Mice
Gillian Minty¹, Nan-Hua Chang², Kieran Manion³, Yuriy Baglaenko¹, Evelyn Pau⁴ and Joan E. Wither⁵, ¹Immunology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Genetics and Development, Toronto Western Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ³Immunology, University of Toronto, Toronto, ON, Canada, ⁴Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁵1E420/Div of Rheumatology, Toronto Western Research Institute, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: New Zealand Black (NZB) mice develop a spontaneous lupus-like autoimmune disease, similar to human systemic lupus erythematosus. Genetic mapping studies have linked loci on…
Abstract Number: 2523 • 2013 ACR/ARHP Annual Meeting
Inflammatory Arthritis Activity During Pregnancy In Systemic Lupus Erythematosus
Sara K. Tedeschi, Bonnie L. Bermas and Karen H. Costenbader, Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: While overall SLE disease and lupus nephritis activity during pregnancy have been studied, the activity of inflammatory arthritis during SLE pregnancy has not been…
Abstract Number: 1064 • 2013 ACR/ARHP Annual Meeting
Trends In Hospitalizations Due To Organ Damage In Patients With Systemic Lupus Erythematosus In Canada, 2006-2010
Amyn Sayani¹, Neerav Monga², Marni Freeman² and Jorge Alfonso Ross Terres³, ¹Medical Affairs, GlaxoSmithKline, Mississauga, ON, Canada, ²Health Economics and Outcomes Research, Medical Division, GlaxoSmithKline, Inc., Mississauga, ON, Canada, ³Medical Affairs, GlaxoSmithKline, Inc., Mississauga, ON, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can affect multiple organs in the body, including the heart, kidney and lung, leading to…
Abstract Number: 568 • 2013 ACR/ARHP Annual Meeting
Pneumococcal Polysaccharide Vaccination Regulates T and B Lymphocyte Cytokine Responses and Decreases Kidney Stat1 Levels In MRL/Lpr Mice In Vivo
Victor Gazivoda¹, Shikha Mehta², Luhan Wang³, Julia Ash⁴, Kirk E. Sperber³ and Ioannis Tassiulas³, ¹Medicine, New York Medical College, Valhalla, NY, ²New York Medical College, Valhalla, NY, ³Medicine-Rheumatology, New York Medical College, Valhalla, NY, ⁴Rheumatology, New York Medical College, Valhalla, NY
Background/Purpose: Zwitterionic polysaccharides can activate CD4+ T cells after processing and presentation by antigen-presenting cells. The 23-valent capsular polysaccharide pneumococcal vaccine, PneumoVax, protects against invasive…
Abstract Number: 2521 • 2013 ACR/ARHP Annual Meeting
Correlation Of Anti Single and Double Stranded DNA Antibodies and Disease Activity In Systemic Lupus Erythematosus
Cecilia Catoggio, Cecilia Reimundes and Carlos Edgardo Perandones, Rheumatology and Immunology, CEMIC, Buenos Aires, Argentina
Background/Purpose: Anti DNA antibodies are considered a hallmark of systemic lupus erythematosus (SLE). Anti double stranded DNA antibody (dsDNA) is part of the SLE classification…
Abstract Number: 1069 • 2013 ACR/ARHP Annual Meeting
Racial Differences In Systemic Lupus Erythematosus Patients’ Treatment Preferences: A Two-Site Study
Ernest R. Vina¹, Tammy O. Utset², Michael J. Hannon³, Nicole Roberts⁴, Christopher M. Masi⁵ and C. Kent Kwoh⁶, ¹Division of Rheumatology and Clinical Immunology, University of Pittsburgh and VA Pittsburgh Healthcare System, Pittsburgh, PA, ²Rheumatology, University of Chicago Medical Center, Chicago, IL, ³Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁴Rheumatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Internal Medicine, NorthShore University Health System, Evanston, IL, ⁶School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Racial disparities in systemic lupus erythematosus (SLE) exist, with African-American (AA) patients experiencing higher lupus damage scores and disease activity than white (WH) patients. …
Abstract Number: 545 • 2013 ACR/ARHP Annual Meeting
Preferential Infiltration Of Double-Negative (DN) T Cells Into The Glomeruli Of NZM 2328 Lupus Mice
Ning Yu, Shunhua Guo, William Stohl and Chaim O. Jacob, Division of Rheumatology, University of Southern California Keck School of Medicine, Los Angeles, CA
Background/Purpose: Lupus nephritis affects at least 50% of patients with SLE and is a major cause of morbidity. The pathologic picture of lupus nephritis is…

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