Abstracts tagged "Lupus"

Abstract Number: 1605 • 2014 ACR/ARHP Annual Meeting
Elevated Regulatory Mediators and Interferon Gamma Associated Responses, but Not Interferon Alpha, BLyS or IP-10, Accompany High-Titer Anti-Ro Autoantibodies in Asymptomatic Mothers of Children with Neonatal Lupus
Peter M. Izmirly¹, Robert M. Clancy², Melissa Munroe³, Sara Rasmussen², Amit Saxena^2,4, Jose U. Scher², Aikaterini Thanou⁵, Stan Kamp⁶, Joan T. Merrill⁷, Jill P. Buyon² and Judith James⁸, ¹Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Rheumatology, New York University School of Medicine, New York, NY, ⁵Arthritis and Clinical Immunology Reseach Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁷Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁸Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Mothers of children with neonatal lupus offer a unique opportunity to study the drivers and consequences of autoantibody production in the absence of ongoing…
Abstract Number: 687 • 2014 ACR/ARHP Annual Meeting
Effect of Corticosteroid Use By Dose on the Risk of Developing Organ Damage over Time in Systemic Lupus Erythematosus—the Hopkins Lupus Cohort
Sarah Al Sawah¹, Xiang Zhang¹, Baojin Zhu¹, Laurence S. Magder², Shonda A Foster¹, Noriko Iikuni¹ and Michelle Petri³, ¹Eli Lilly and Company, Indianapolis, IN, ²Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD, ³Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Reduction of corticosteroid dose remains an important goal in the management of systemic lupus erythematosus (SLE). Current standard of care in SLE relies heavily…
Abstract Number: 2523 • 2013 ACR/ARHP Annual Meeting
Inflammatory Arthritis Activity During Pregnancy In Systemic Lupus Erythematosus
Sara K. Tedeschi, Bonnie L. Bermas and Karen H. Costenbader, Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: While overall SLE disease and lupus nephritis activity during pregnancy have been studied, the activity of inflammatory arthritis during SLE pregnancy has not been…
Abstract Number: 1064 • 2013 ACR/ARHP Annual Meeting
Trends In Hospitalizations Due To Organ Damage In Patients With Systemic Lupus Erythematosus In Canada, 2006-2010
Amyn Sayani¹, Neerav Monga², Marni Freeman² and Jorge Alfonso Ross Terres³, ¹Medical Affairs, GlaxoSmithKline, Mississauga, ON, Canada, ²Health Economics and Outcomes Research, Medical Division, GlaxoSmithKline, Inc., Mississauga, ON, Canada, ³Medical Affairs, GlaxoSmithKline, Inc., Mississauga, ON, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can affect multiple organs in the body, including the heart, kidney and lung, leading to…
Abstract Number: 568 • 2013 ACR/ARHP Annual Meeting
Pneumococcal Polysaccharide Vaccination Regulates T and B Lymphocyte Cytokine Responses and Decreases Kidney Stat1 Levels In MRL/Lpr Mice In Vivo
Victor Gazivoda¹, Shikha Mehta², Luhan Wang³, Julia Ash⁴, Kirk E. Sperber³ and Ioannis Tassiulas³, ¹Medicine, New York Medical College, Valhalla, NY, ²New York Medical College, Valhalla, NY, ³Medicine-Rheumatology, New York Medical College, Valhalla, NY, ⁴Rheumatology, New York Medical College, Valhalla, NY
Background/Purpose: Zwitterionic polysaccharides can activate CD4+ T cells after processing and presentation by antigen-presenting cells. The 23-valent capsular polysaccharide pneumococcal vaccine, PneumoVax, protects against invasive…
Abstract Number: 2521 • 2013 ACR/ARHP Annual Meeting
Correlation Of Anti Single and Double Stranded DNA Antibodies and Disease Activity In Systemic Lupus Erythematosus
Cecilia Catoggio, Cecilia Reimundes and Carlos Edgardo Perandones, Rheumatology and Immunology, CEMIC, Buenos Aires, Argentina
Background/Purpose: Anti DNA antibodies are considered a hallmark of systemic lupus erythematosus (SLE). Anti double stranded DNA antibody (dsDNA) is part of the SLE classification…
Abstract Number: 1069 • 2013 ACR/ARHP Annual Meeting
Racial Differences In Systemic Lupus Erythematosus Patients’ Treatment Preferences: A Two-Site Study
Ernest R. Vina¹, Tammy O. Utset², Michael J. Hannon³, Nicole Roberts⁴, Christopher M. Masi⁵ and C. Kent Kwoh⁶, ¹Division of Rheumatology and Clinical Immunology, University of Pittsburgh and VA Pittsburgh Healthcare System, Pittsburgh, PA, ²Rheumatology, University of Chicago Medical Center, Chicago, IL, ³Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁴Rheumatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Internal Medicine, NorthShore University Health System, Evanston, IL, ⁶School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Racial disparities in systemic lupus erythematosus (SLE) exist, with African-American (AA) patients experiencing higher lupus damage scores and disease activity than white (WH) patients. …
Abstract Number: 545 • 2013 ACR/ARHP Annual Meeting
Preferential Infiltration Of Double-Negative (DN) T Cells Into The Glomeruli Of NZM 2328 Lupus Mice
Ning Yu, Shunhua Guo, William Stohl and Chaim O. Jacob, Division of Rheumatology, University of Southern California Keck School of Medicine, Los Angeles, CA
Background/Purpose: Lupus nephritis affects at least 50% of patients with SLE and is a major cause of morbidity. The pathologic picture of lupus nephritis is…
Abstract Number: 2529 • 2013 ACR/ARHP Annual Meeting
Improved Outcomes In High Risk Lupus Pregnancies: Usefulness Of a Protocol Based Multidisciplinary Approach In Kerala, India
Vinod Ravindran¹, S Bhadran², P Shyjus³, M Divakaran⁴ and V Reshma⁵, ¹Department of Rheumatology, MES Medical College, Kerala, INDIA, Perinthalmanna, India, ²Department of Obstetrics, National Hospital, Calicut, India, ³Department of Obstetrics, MES Medical College, Perinthalmanna, India, ⁴Department of Obstetrics, PVS Hospital, Calicut, India, ⁵Department of Obstetrics, Indira Gandhi Hospital, Thalassery, India
Background/Purpose: In patients with SLE who had previous adverse obstetric outcome(s) the risk of an adverse outcome in subsequent pregnancy rises. The primary objective of…
Abstract Number: 990 • 2013 ACR/ARHP Annual Meeting
Utilizing Facebook Chats To Convey Health Information To Lupus Patients At The Systemic Lupus Erythematosus – Antiphospholipid Syndrome Center Of Excellence At Hospital For Special Surgery
Nadine H. Spring¹, Elyse Bernstein², Su Jin Kim³, Monica C. Richey¹, Jessica Rowshandel⁴ and Jane E. Salmon¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Public Relations, Hospital for Special Surgery, New York, NY, ³Department of Social Work Programs, Hospital for Special Surgery, New York, NY, ⁴S.L.E. Lupus Foundation, New York, NY
Background/Purpose: The SLE-APS Center of Excellence at Hospital for Special Surgery (HSS) uses Facebook chats as a means to increase awareness, reach a wider audience,…
Abstract Number: 550 • 2013 ACR/ARHP Annual Meeting
Neutrophil Gelatinase Associated Lipocalin (NGAL/Lipocalin-2) Regulates the Onset Of Serum Autoantibodies In Pristane Induced Lupus
Rahul Pawar¹, Beatrice Goilav², Yumin Xia¹, Haoyang Zuang³, Leal Herlitz⁴, Westley H. Reeves⁵ and Chaim Putterman⁶, ¹Albert Einstein College of Medicine, Bronx, NY, ²Division of Nephrology, Children's Hospital at Montefiore, Bronx, NY, ³University of Florida, Gainesville, FL, ⁴The Department of Pathology, Columbia University Medical Center, New York, NY, ⁵Medicine, University of Florida, Gainesville, FL, ⁶The Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: NGAL (lipocalin-2), a member of the lipocalin superfamily, is expressed by a variety of cells including neutrophils, hepatocytes, alveolar epithelial cells and renal resident…
Abstract Number: 2511 • 2013 ACR/ARHP Annual Meeting
Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification
Majed M. Khraishi¹, Rana Aslanov², Sanjay Dixit³, Krista Fudge⁴, Vandana Ahluwalia⁵ and Sarah Khraishi⁶, ¹Nexus Clinical Research, St John's, NF, Canada, ²Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada, ⁵Past President, Ontario Rheumatology Association, Brampton, ON, Canada, ⁶Nexus Clinical Research, Memorial University of Newfoundland, St.John's, NF, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic immune modulated disease with variable clinical manifestations. New advances in the management of SLE mandated closer monitoring…
Abstract Number: 988 • 2013 ACR/ARHP Annual Meeting
Lupus Education For Providers Serving The Asian American Community: Hospital For Special Surgery’s LANtern® (Lupus Asian Network) Initiative
My-Lan N. Tran¹, Roberta Horton², Michael D. Lockshin³ and Arthur Yee⁴, ¹Social Work Programs, Hospital for Special Surgery, New York City, NY, ²Department of Social Work Programs, Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ⁴Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Lupus affects Asian Americans 2-3 times more than their white counterparts, with studies demonstrating health disparities in severity and outcomes. Our hospital’s national support…
Abstract Number: 551 • 2013 ACR/ARHP Annual Meeting
Different Cell Death Programs Contribute To Severity Of Lupus Glomerulonephritis In Males and Females
Neelakshi Jog¹ and Roberto Caricchio², ¹Rheumatology, Temple University, Philadelphia, PA, ²Medicine/Rheumatology, Temple University, Philadelphia, PA
Background/Purpose: Lupus glomerulonephritis (GN) is a leading cause of long-term disability in SLE. Although lupus is more common in females, GN occurs earlier and in…
Abstract Number: 2901 • 2013 ACR/ARHP Annual Meeting
Standardized Incidence Ratios For Cancer After Renal Transplant In Systemic Lupus Erythematosus and Non-Systemic Lupus Erythematosus Recipients
Rosalind Ramsey-Goldman¹, Amarpali Brar², Moro Salifu², Ann E. Clarke³, Rahul M. Jindal⁴ and Sasha Bernatsky³, ¹Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine, SUNY Downstate, Brooklyn, NY, ³McGill University, Montreal, QC, Canada, ⁴Surgery, Uniformed Services University and George Washington University, Washington, DC
Background/Purpose: Differentiating between effects of drugs vs. disease activity on cancer risk in SLE is difficult. Because all renal transplant recipients are on similar immunomodulatory…

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