Abstracts tagged "Lupus"

Abstract Number: 1596 • 2017 ACR/ARHP Annual Meeting
Effect of the Metabolic Syndrome on Organ Damage, Renal Function and Mortality in Patients with Systemic Lupus Erythematosus: A Longitudinal Analysis
Chi Chiu Mok¹, Sau Mei Tse¹ and Ling Yin Ho², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong
Background/Purpose: To study the effect of the metabolic syndrome (MetS) on organ damage, renal function and mortality in patients with SLE. Methods: Consecutive patients who…
Abstract Number: 2033 • 2017 ACR/ARHP Annual Meeting
Low Health Literacy Does Not Impact Adherence to Hydroxychloroquine in Patients with Systemic Lupus
Alexandra Perel-Winkler¹, Kayla Neville², Samantha Nguyen¹, Miya Okado¹, James Miceli¹, Jon T. Giles³ and Anca Askanase¹, ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Columbia University College of Physicians & Surgeons, New York, NY, ³Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Background/Purpose: Low health literacy has been associated with poor health outcomes and increased hospital admissions. Adherence to medication has been shown to significantly impact mortality, morbidity,…
Abstract Number: 2813 • 2017 ACR/ARHP Annual Meeting
Interferon-Induced APOL1 over-Expression Causes Autophagic Dysfunction and Mitochondrial Stress in Risk Variant-Carrying Endothelial Cells
Ashira Blazer¹, Sara Rasmussen², Androo Markham³, Shilpi Mehta-Lee⁴, Jill P. Buyon⁴ and Robert M. Clancy², ¹Division of Rheumatology, NYU School of Medicine, New York, NY, ²Department of Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, ³Medicine, NYU School of Medicine, New York, NY, ⁴NYU School of Medicine, New York, NY
Background/Purpose: In SLE Apolipoprotein L1 (APOL1) risk variants (RV) associate with cardiovascular and end stage renal disease. APOL1 induction initially promotes cellular maintenance through autophagy;…
Abstract Number: 844 • 2017 ACR/ARHP Annual Meeting
Social Support, Stress and Health Outcomes in Systemic Lupus Erythematosus: Georgians Organized Against Lupus (GOAL) Cohort
Charmayne M. Dunlop-Thomas, S. Sam Lim, Gaobin Bao and Cristina Drenkard, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA
Background/Purpose: Stress can influence immune and neuroendocrine processes, and may lead to poor outcomes in people with systemic lupus erythematosus (SLE). Social support can potentially…
Abstract Number: 1616 • 2017 ACR/ARHP Annual Meeting
Early and Late Onset Biopsy Proven Lupus Nephritis without Other Associated Autoimmune Diseases: Severity and Long-Term Outcome
Michelle Lopes¹, Laryssa Santos², Luciana Seguro³ and Eloisa Bonfa⁴, ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Lupus nephritis (LN) usually develops within the first years of Systemic Lupus Erythematosus (SLE) onset and rarely after that. There are scarce studies comparing…
Abstract Number: 2123 • 2017 ACR/ARHP Annual Meeting
Protein-Losing Enteropathy in Patients with Systemic Autoimmune Diseases: Characterization of 263 Cases (GEAS-SEMI Spanish Cohort)
Alejandra Flores-Chavez^1,2,3, Soledad Retamozo^4,5,6, Angel Robles⁷, Guadalupe Fraile Rodriguez⁸, Sofia Arteaga^9,10, Celeste Galceran-Chaves¹¹, Roberto Pérez-Alvarez¹², Marta Pérez de Lis¹², Belchin Kostov¹³, Manuel Ramos-Casals^14,15 and Pilar Brito-Zerón^14,16, ¹Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona, Spain., Barcelona, Spain, ²Unidad de Investigación Biomédica 02 (Unidad de Investigación en Epidemiología Clínica), UMAE, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Jalisco, Mexico, ³Programa de Doctorado en Ciencias Médicas, Centro Universitario de Investigaciones Biomédicas (CUIB), Universidad de Colima, Colima, Mexico, Mexico, Mexico, ⁴Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas (INICSA-UNC-CONICET), Cordoba, Argentina, ⁵Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Barcelona, Spain, ⁶Rheumatology Unit, Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina, ⁷Department of Internal Medicine, Hospital La Paz, Madrid, Madrid, Spain, ⁸Internal Medicine, Hospital Ramón y Cajal, Madrid, Madrid, Spain, ⁹Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona, Barcelona, Spain, ¹⁰Universidad de Antioquía, Medellín, Colombia, Medellin, Colombia, ¹¹Neuroscience Clinical Institute, Hospital Clínic, Barcelona, Barcelona, Spain, ¹²Department of Internal Medicine, Hospital Alvaro Cunqueiro, Vigo, Vigo, Spain, ¹³Primary Care Research Group, IDIBAPS, Centre d’Assistència Primària ABS Les Corts, CAPSE, Barcelona, Barcelona, Spain, ¹⁴Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ¹⁵Department of Medicine, University of Barcelona, Barcelona, Spain., Barcelona, Spain, ¹⁶Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona., Bacelona, Spain
Background/Purpose: Protein-losing enteropathy (PLE) is a rare condition characterized by a loss of serum protein into the gastrointestinal tract resulting in hypoproteinemia, which can be…
Abstract Number: 2818 • 2017 ACR/ARHP Annual Meeting
Gene Expression Analysis Demonstrates That Multiple Type 1 Interferons Are Involved in Lupus Pathogenesis
Michelle Catalina¹, Prathyusha Bachali², Sushma Madamanchi¹, Amrie Grammer¹ and Peter Lipsky¹, ¹Ampel BioSolutions LLC, Charlottesville, VA, ²Ampel BioSolutions LLC, Charlottesville, MA
Background/Purpose: A role for interferon (IFN) in lupus pathogenesis has been inferred from the prominent IFN gene signature (IGS) found in lupus peripheral blood. However,…
Abstract Number: 26 • 2017 Pediatric Rheumatology Symposium
Gray Matter Volume Loss in Youth with SLE
Andrea Knight¹, Michelle Vickery², Arastoo Vossough³, Guray Erus⁴, Jimit Doshi⁵ and Susan Furth⁶, ¹Center for Pediatric Clinical Effectiveness & PolicyLab, Philadelphia, PA, ²PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, ³Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Section on Biomedical Image Analysis, University of Pennsylvania, Philadelphia, PA, ⁵Section of Biomedical Image Analysis, University of Pennsylvania, Philadelphia, PA, ⁶Division of Nephrology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Neuropsychiatric SLE in children and adolescents presents diagnostic challenge due to limitations of conventional magnetic resonance imaging (MRI) to detect clinically relevant brain changes.…
Abstract Number: 98 • 2017 Pediatric Rheumatology Symposium
Contraceptive use, Counseling given and the Occurrence of Venous Thrombus Embolism in Adolescent Systemic Lupus Erythematosus
Martha Curry¹, Jennifer Kurkowski², Jane Geyer³, Julie Hakim³, Haleh Sangi⁴ and Marietta deGuzman⁵, ¹Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Division Pediatric and Adolescent Gynecology, Houston, TX, ³Baylor College of Medicine, Division of Pediatric and Adolescent Gynecology, Houston, TX, ⁴Baylor College of Medicnine,Division of Pediatric and Adolescent Gynecology, Houston, TX, ⁵Baylor College of Medicine, Division of Pediatric Rheumatology, Houston, TX
Background/Purpose: According to the Center for Disease Control, 46.8% of high school students surveyed in 2013 have been sexually active. Of those surveyed 34% had…
Abstract Number: 27 • 2017 Pediatric Rheumatology Symposium
Assessing the Safety of Kidney Biopsies Performed on Childhood-onset Systemic Lupus Erythmatosus Patients
Shreya Goyal¹, Daniel Ashton^2,3, Kamlesh Kukreja^3,4, Michael C. Braun^5,6 and Scott E. Wenderfer^5,7, ¹Pediatrics, Baylor College of Medicine, Houston, TX, ²Interventional Radiology, Texas Children's Hospital, Houston, TX, ³Radiology, Baylor College of Medicine, Houston, TX, ⁴Interventional RAdiology, Texas Children's Hospital, Houston, TX, ⁵Texas Children's Hospital, Houston, TX, ⁶Pediatrics-Renal, Baylor College of Medicine, Houston, TX, ⁷Pediatrics-Renal, Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Title: Assessing the Safety of Kidney Biopsies Performed on Childhood-onset Systemic Lupus Erythematosus Patients Background/Purpose: There is very little data in the literature on…
Abstract Number: 35 • 2017 Pediatric Rheumatology Symposium
Kv1.3 Expression on Urinary Leukocytes in Lupus Nephritis: Potential for Targeted Immunotherapy
Anne Stevens¹, Andrew Hinkle², Megan Yuasa³, David Peckham⁴, Chelsea Olsen⁵, Craig Philips⁵, Shawn P. Iadonato⁴ and Peter Probst⁶, ¹University of Washington, Pediatrics, Seattle, WA, ²Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, ³Seattle Children’s Research Institute, Seattle, WA, ⁴Kineta Inc, Seattle, WA, ⁵KPI Therapeutics, Inc., Seattle, WA, ⁶Kineta, Inc, Seattle, WA
Background/Purpose: Lymphocyte activation depends upon a calcium signaling cascade that is regulated by voltage-gated potassium channels. Effector memory T cells (TEM), which are implicated in…
Abstract Number: 7 • 2017 Pediatric Rheumatology Symposium
Activation of Immature, Transitional B cells by Integrated BCR, TLR and TACI signals promotes systemic autoimmunity in high BAFF settings
Holly Jacobs, Samuel Du, Tanvi Arkatkar and Shaun Jackson, Seattle Children's Research Institute, Seattle, WA
Background/Purpose: B cell activating factor of the TNF family (BAFF, also known as BLyS) promotes B cell survival and activation by binding distinct B cell…
Abstract Number: 446 • 2016 ACR/ARHP Annual Meeting
A Multi-Group Confirmatory Factor Analyses of the Lupuspro Between Southern California and Filipino Samples of Patients with SLE
Desiree Azizoddin¹, R. Olmstead², Chelsie Cost³, Geraldine Zamora Racaza⁴, Julia Ayeroff⁵, Lekeisha Sumner⁶, Michael Weisman⁷, Perry M. Nicassio⁸ and Meenakshi Jolly⁹, ¹Department of Psychology, Loma Linda University, Loma Linda, CA, ²UCLA, Los Angeles, CA, ³Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ⁴Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Postbaccalaureate Premedical Program, University of Southern California, Los Angeles, CA, CA, ⁶Department of Psychology, Cedars Sinai Medical Center, Los Angeles, CA, ⁷Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁸Cousins Center for PNI, UCLA, LA, CA, ⁹Rush, Chicago, IL
Background/Purpose: Systemic lupus erythematosus (SLE) leads to a variety of health outcomes through complex disease paths. The LupusPro (LP) is a comprehensive self-report measure which…
Abstract Number: 1175 • 2016 ACR/ARHP Annual Meeting
Thirty Day Readmission Rates for Patients Diagnosed with Systemic Lupus Erythematosus: Analysis at a Tertiary Care Center
Sadiq Ali¹, Stephen Mullis², Nkechi Emejuaiwe¹ and Dennis Ang¹, ¹Section on Rheumatology and Immunology, Wake Forest University, Winston Salem, NC, ²Department of Internal Medicine, Wake Forest University, Winston Salem, NC
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic illness that has been associated with high hospital readmission rates. Based on a recently published (Arth Rheumatol…
Abstract Number: 1838 • 2016 ACR/ARHP Annual Meeting
Antibodies Against Bacterial Products Curli/DNA Are Found in Lupus Patients and Are Associated with Disease Flares
Ryan Pachucki¹, Sarah Tursi², Chelsea Corradetti¹, Lynne Kohler³, Stefania Gallucci², Cagla Tukel² and Roberto Caricchio¹, ¹Medicine Rheumatology, Lewis Katz School of Medicine, Philadelphia, PA, ²Microbiology and Immunology, Lewis Katz School of Medicine, Philadelphia, PA, ³Lewis Katz School of Medicine, Philadelphia, PA
Background/Purpose: Bacterial infections are a major contributor to morbidity and mortality in SLE, a known trigger of flares and they are often difficult to distinguish…

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