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Abstracts tagged "Lupus nephritis"

  • Abstract Number: 2153 • 2018 ACR/ARHP Annual Meeting

    The Effect of Socioeconomic Status on Treatment Outcomes in Lupus Nephritis: Private Versus Public Insurance

    Arezoo Haghshenas1, Phildrich Teh2, Kristal Choi3, Abigail Benitez4, Lorena Salto3, Mathew Firek5, Karina Torralba6 and Vaneet K. Sandhu1, 1Division of Rheumatology, Loma Linda University, Loma Linda, CA, 2Internal Medicine, University of California, Riverside, Riverside, CA, 3Loma Linda University, Loma Linda, CA, 4Rheumatology, Loma Linda University, Loma Linda, CA, 5Riverside university health system, Moreno valley, CA, 6Loma Linda University Medical Center, Loma Linda, CA

    Background/Purpose: Despite therapeutic advancements, lupus nephritis (LN) remains a major cause of mortality among patients with SLE. Loma Linda University Health serves a region in…
  • Abstract Number: 2416 • 2018 ACR/ARHP Annual Meeting

    Good Pregnancy and Neonatal Outcomes in Lupus Nephritis Patients with Complete Remission

    Weixin HU, Kang LI, Yinghua CHEN, Zhenzhao LIU, Liu YANG, Duqun CHEN and Haitao Zhang, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China

    Background/Purpose: To investigate the outcomes of pregnancy and neonatal and the risk factors of lupus flares and pregnancy complications in Chinese patients with lupus nephritis…
  • Abstract Number: 2436 • 2018 ACR/ARHP Annual Meeting

    The Impact of Different Classes of Lupus Nephritis on Maternal and Fetal Outcomes

    Bruna Costa Rodrigues1, Marcela Ignacchiti Lacerda1, Guilherme Ramires de Jesus2, Flavia Cunha dos Santos2, Nilson Ramires de Jesus2, Roger Abramino Levy1,3 and Evandro Mendes Klumb1, 1Rheumatology, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 2Obstetrics, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 3Immunology and Inflammation, GlaxoSmithKline, Upper Providence, PA

    Background/Purpose: During pregnancy, history of lupus nephritis (LN) has been independently associated with increased risk of adverse maternal and fetal outcomes, which are even more…
  • Abstract Number: 2636 • 2018 ACR/ARHP Annual Meeting

    Investigating Lupus Nephritis Patient Outcomes Receiving Belatacept Post Renal Transplant Using the UNOS Database

    Osman Bhatty1, Sarah Aurit2, Rouhin Sen3, Joseph Nahas4 and Sunil Jagadesh5, 1Department of Medicine, CHI Creighton University Medical Center, New Hempstead, NY, 2Department of Surgery, CHI Creighton University Medical Center, Omaha, NE, 3Internal Medicine, CHI Creighton University Medical Center, Omaha, NE, 4Department of Rheumatology, CHI Creighton University Medical Center, Omaha, NE, 5Department of Nephrology, CHI Creighton University Medical Center, Omaha, NE

    Background/Purpose: Twenty to sixty percent of patients with systemic lupus erythematous (SLE) can progress to lupus nephritis (LN) and those that do can develop end…
  • Abstract Number: 2662 • 2018 ACR/ARHP Annual Meeting

    Changes in Blood Pressure and Proteinuria at One Year in Two Lupus Nephritis Clinical Trials

    L. Michelle Gomez Mendez1, Marco Prunotto2, Jian Dai3, Paul Brakeman1, Maria Dall'Era1, Jay Garg3 and Matthew Cascino3, 1UCSF, San Francisco, CA, 2Hoffmann-La Roche, Basel, Switzerland, 3Genentech, Inc., South San Francisco, CA

    Background/Purpose: Hypertension predicts poor long-term renal outcomes for patients with lupus nephritis (LN) [1, 2]. We sought to characterize relationships between blood pressure and proteinuria…
  • Abstract Number: PP11 • 2018 ACR/ARHP Annual Meeting

    The Road Less Traveled– Nontraditional Approaches to Increased Patient Adherence and Positive Outcomes

    Carlene Harrison, AstraZeneca, Gaithersburg, MD

    Background/Diagnosis: African-American female diagnosed with SLE, Lupus Nephritis, Discoid Lupus, and Raynaud’s Phenomenon in 2011. Symptoms included joint pain, edema in the ankles, malar rash,…
  • Abstract Number: 2851 • 2018 ACR/ARHP Annual Meeting

    NF-Κappa b Signaling in the Myeloid Cell Lineage Drives the Pathogenesis of Immune-Mediated Nephritis

    Samantha Chalmers1, Sayra Garcia1, Justine Shum1, Leal Herlitz2 and Chaim Putterman3, 1Albert Einstein College of Medicine, Bronx, NY, 2Cleveland Clinic, Cleveland, OH, 3Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY

    Background/Purpose: Immune-mediated glomerulonephritis is a serious end organ pathology that commonly affects patients with systemic lupus erythematosus (SLE). Nephrotoxic serum nephritis, induced by passive transfer…
  • Abstract Number: 173 • 2017 ACR/ARHP Annual Meeting

    Applying Urine Proteomics for Discovery of Lupus Nephritis Damage Biomarkers in a Pediatric Cohort

    Jessica Turnier1, Bruce Aronow2, Kenneth Greis3, Michael Bennett4, Wendy Haffey3, Sherry Thornton5, Gaurav Gulati6, Michael Wagner7, David Witte8, Prasad Devarajan9 and Hermine I. Brunner10, 1Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Computational Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3University of Cincinnati College of Medicine, Cincinnati, OH, 4Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, 7Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 8Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9Nephrology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 10Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Non-invasive biomarkers of lupus nephritis (LN) damage are needed to guide treatment decisions and determine risk for kidney failure. Urinary proteomics has advanced as…
  • Abstract Number: 665 • 2017 ACR/ARHP Annual Meeting

    Low Vitamin D Is Associated with End Stage Renal Disease in Systemic Lupus Erythematosus

    Michelle Petri1, Wei Fu2 and Daniel Goldman2, 1Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Vitamin D insufficiency/deficiency is common in SLE. Replacement therapy may help renal disease activity. We asked whether low vitamin D predicted later organ damage.…
  • Abstract Number: 668 • 2017 ACR/ARHP Annual Meeting

    Is Uric Acid Level a Predictor of Long-Term Renal Outcome in Lupus Nephritis?

    Michelle Lopes1, Samara Gavinier2, Elaine Leon2, Vilma Viana2, Eduardo Ferreira Borba1 and Eloisa Bonfa3, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, São Paulo, Brazil, 3Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Hyperuricemia has been reported to be associated with chronic kidney disease (CKD) in several clinical conditions, and recent studies also observed an association between…
  • Abstract Number: 671 • 2017 ACR/ARHP Annual Meeting

    A New Histological Index for Predicting a Decline in Kidney Function in Patients with Lupus Nephritis. a Mexican Cohort Study of 186 Patients with a Kidney Biopsy

    Marco Ulises Martinez-Martinez1, Cesar Eduardo Vallín Orozco2, David Martínez-Galla3 and Carlos Abud-Mendoza4, 1Unidad de Investigaciones Reumatológicas, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico, 2Rheumatology, Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico, 3Pathology, Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico, 4Unidad de Investigaciones Reumatológicas y Osteoporosis, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico

    -       Background/Purpose: The NIH indexes (of activity and chronicity) were proposed by Austin et al., in 1984. At the moment, there are therapies which can…
  • Abstract Number: 672 • 2017 ACR/ARHP Annual Meeting

    Baseline Hyperuricemia As a Predictive Value for Development of Lupus Nephritis in Premenopausal SLE Patients

    Doo-Ho Lim1, Seokchan Hong2, Ji Seon Oh3, Yong-Gil Kim2, Chang Keun Lee2, Seung Won Choi1 and Bin Yoo2, 1Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 3Division of Rheumatology, Department of Internal Medicine, National Medical Center, Seoul, Korea, Republic of (South)

    Background/Purpose: Although lupus nephritis is a common and serious manifestation of SLE, there have been few predictive markers for development of lupus nephritis in SLE…
  • Abstract Number: 702 • 2017 ACR/ARHP Annual Meeting

    Positive Direct Coombs’ Test in the Absence of Hemolytic Anemia Predicts High Disease Activity and Poor Renal Response in Systemic Lupus Erythematosus

    Hironari Hanaoka, Harunobu Iida, Tomofumi Kiyokawa, Yukiko Takakuwa and Kimito Kawahata, Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Direct Coombs' test in the absence of hemolytic anemia was newly included in the immunologic criterion of the SLICC/ACR 2012 criteria for SLE. Since…
  • Abstract Number: 1843 • 2017 ACR/ARHP Annual Meeting

    Serum Albumin at 12 Months Post Biopsy Has Excellent Sensitivity and Specificity for Favorable 4 Year Renal Outcome in Lupus Nephritis (LN)

    Vinicius Domingues1, Nicole Bornkamp1, Benjamin A. Levinson2, Judith D. Goldberg2, Jill P. Buyon1 and H. Michael Belmont1, 1Medicine, New York University School of Medicine, New York, NY, 2Population Health, New York University School of Medicine, New York, NY

    Background/Purpose:  LN is a common, deleterious manifestation of systemic lupus erythematosus (SLE) and despite recent advances in treatment remains the most significant end organ injury…
  • Abstract Number: 1920 • 2017 ACR/ARHP Annual Meeting

    Tacrolimus Induces Remission in Refractory and Relapsing Lupus Nephritis By Decreasing P-Glycoprotein Expression and Function on Peripheral Blood Lymphocytes

    Vikas Gupta, Sukesh Edavalath, Mohit Kumar Rai, Harshit Singh, Saurabh Chaturvedi and Vikas Agarwal, Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

     Background/Purpose: About 15-30% of Lupus Nephritis (LN) patients do not respond to first-line immunosuppressive therapy. P-glycoprotein (P-gp) mediated efflux of corticosteroids (CS) may contribute to…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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