ACR Meeting Abstracts

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Abstracts tagged "Lupus and SLE"

  • Abstract Number: 1573 • 2019 ACR/ARP Annual Meeting

    Incidence and Predictors of Atherosclerotic Vascular Events in a Multicentre Inception SLE Cohort

    Murray Urowitz1, Dafna Gladman 2, Jiandong Su 1, Vernon Farewell 3, Jorge Sanchez-Guerrero 4, Juanita Romero-Diaz 5, Sang-Cheol Bae 6, Paul Fortin 7, Ola Nived 8, Ann E Clarke 9, Sasha Bernatsky 10, Caroline Gordon 11, John Hanly 12, Daniel J Wallace 13, David A Isenberg 14, Anisur Rahman 15, Joan Merrill 16, Ellen M Ginzler 17, Graciela Alarcon 18, Michelle Petri 19, Ian Bruce 20, Munther A Khamashta 21, Cynthia Aranow 22, Susan Manzi 23, MA Dooley 24, Rosalind Ramsey-Goldman 25, Andreas Jönsen 8, Kristjan Steinsson 26, Asad Zoma 27, Guillermo Ruiz-Irastorza 28, S Sam Lim 29, Kenneth C Kalunian 30, Murat Inanc 31, Ronald van Vollenhoven 32, Manuel Ramos 33, Diane Kamen 34, Soren Jacobsen 35, Christine Peschken 36, Anca Askanase 37 and Thomas Stoll 38, 1University Health Network, University of Toronto, Toronto, ON, Canada, 2Toronto Western Hospital, Toronto, Canada, Toronto, ON, Canada, 3University of Cambridge, Cambridge, United Kingdom, 4Toronto Western Hospital, Toronto, ON, Canada, 5Instituto Nacional de Ciencias Medicas y Nutricion Salvador, Zubiran Vasco de Quiroga, Mexico City, Mexico, 6Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 7Division de Rhumatologie, Département de Médecine, CHU de Québec – Université Laval, Axe maladies infectieuses et inflammatoires, Centre de recherche du CHU de Québec – Université Laval, Canada, Quebec, QC, Canada, 8Lund University, Lund, Sweden, 9University of Calgary, Calgary, AB, Canada, 10Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 11University of Birmingham, Birmingham, United Kingdom, 12Queen Elizabeth II Health Science Centre (Nova Scotia Rehab Site), Halifax, NS, Canada, 13Cedars-Sinai Medical Centre, Beverly Hills, CA, 14Centre for Rheumatology, London, United Kingdom, 15University College London, London, United Kingdom, 16Oklahoma Medical Research Foundation, Oklahoma City, 17State University of New York Downstate Medical Center, Brooklyn, NY, 18The University of Alabama at Birmingham, Birmingham, AL, 19Johns Hopkins University School of Medicine, Baltimore, MD, 20University of Manchester, Manchester, United Kingdom, Manchester, England, United Kingdom, 21King's College London School of Medicine, London, United Kingdom, 22Feinstein Institute for Medical Research, Manhasset, NY, 23Allegheny Health Network, Pittsburg, PA, 24UnC Kidney Centre, Chapel Hill, NC, 25Northwestern University, Chicago, IL, 26Landspitali, University Hospital, Reykjavik, Iceland, 27Lanarkshire Centre for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland, United Kingdom, 28Unidad de Enfermedades Autoinmunes, BioCruces Health Research Institute, Bizkaia, Spain, 29Emory University, Atlanta, GA, 30UC San Diego School of Medicine, LaJolla, CA, 31Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 32Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, the Netherlands, Amsterdam, Netherlands, 33Department of Internal Medicine, Hospital Nuestra Señora del Prado, Talavera, Talavera, Spain, Talavera, Spain, 34Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Charleston, SC, 35Copenhagen Lupus and Vasculitis Clinic, Copenhagen, Denmark, 36University of Manitoba, Winnipeg, Canada, 37Columbia University Medical Center, New York, NY, 38University of Glasgow, Kilbride, Scotland, United Kingdom

    Background/Purpose: The prevalence of atherosclerotic vascular events (AVE) in published literature of an inception cohort with SLE is 10%. We aimed to investigate the accrual…
  • Abstract Number: 1185 • 2018 ACR/ARHP Annual Meeting

    Cause and Rate of Hospitalization of Lupus Patients

    Reem Aldarmaki1, Hiba Khogali2 and Ali AlDhanhani3, 1Medical Student, UAEU, College of Medicine, Al Ain, United Arab Emirates, 2Rheumatologist, Tawam hospital, SEHA, Al Ain, United Arab Emirates, 3Assistant professor, UAEU, College of Medicine, Al Ain, United Arab Emirates

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic multiorgan disease that is associated with significant morbidity and mortality. Literature suggests improvement in the survival rates…
  • Abstract Number: 2157 • 2018 ACR/ARHP Annual Meeting

    Nationwide Estimated Prevalence of SLE: United States Population-Based Study, 2001-2011

    KimNgan P. Nguyen1, Eric Yen2, Ning Li3 and Ram R. Singh2, 1David Geffen School of Medicine, UCLA, LOS ANGELES, CA, 2UCLA, Los Angeles, CA, 3Biomathematics, University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: In the published literature, the prevalence rates of SLE have widely varied by as much as 12-fold over the years. This is likely due…
  • Abstract Number: 6L • 2017 ACR/ARHP Annual Meeting

    Efficacy and Safety of Ustekinumab, an Interleukin 12/23 Inhibitor, in Patients with Active Systemic Lupus Erythematosus: Results of a Phase 2, Randomized Placebo-Controlled Study

    Ronald van Vollenhoven1, Bevra H. Hahn2, George C. Tsokos3, Carrie Wagner4, Peter Lipsky5, Benjamin Hsu4, Marc Chevrier4, Robert Gordon4, Manon Triebel6 and Shawn Rose4, 1Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, Netherlands, 2UCLA David Geffen School of Medicine, Los Angeles, CA, 3Division of Rheumatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 4Janssen Research & Development, LLC, Spring House, PA, 5Ampel BioSolutions LLC, Charlottesville, VA, 6Janssen Biologics Europe, Leiden, Netherlands

    Background/Purpose: The IL-12/23 pathway has been implicated in the pathogenesis of SLE. The anti-IL12/23 monoclonal antibody ustekinumab (UST) is efficacious in the treatment of psoriasis,…
  • Abstract Number: 888 • 2017 ACR/ARHP Annual Meeting

    Phase 3 Trial Results with Blisibimod, a Selective Inhibitor of B-Cell Activating Factor, in Subjects with Moderate-to-Severe Systemic Lupus Erythematosus

    Joan T. Merrill1, Renee S. Martin2, William Shanahan2, Morton Scheinberg3, Kenneth C. Kalunian4 and David Wofsy5, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Anthera, Hayward, CA, 3Department of Immunology, Center for Clinical Immunology, Sao Paulo SP, Brazil, 4Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine, La Jolla, CA, 5Rheumatology, UCSF, San Francisco, CA

    Background/Purpose: The Phase 3 CHABLIS-SC1 trial (NCT01395745) evaluated blisibimod, an inhibitor of B-cell activating factor (BAFF), in SLE. Prior SLE trials suggested that treatments are…
  • Abstract Number: 1808 • 2016 ACR/ARHP Annual Meeting

    Frequency and Factors Associated with Thirty Day Hospital Readmissions Among Systemic Lupus Erythematosus Patients in a Community Hospital in the California Central Valley

    Candice Yuvienco1, Ololade Oladimeji2, Ashenafi Legesse2 and Paul Mills2, 1Internal Medicine, Division of Rheumatology, University of California San Francisco, Fresno Medical Education Program, Fresno, CA, 2Internal Medicine, University of California San Francisco, Fresno Medical Education Program, Fresno, CA

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune condition which has one of the highest rates of hospital readmissions in the United States. There…
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