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Abstracts tagged "Lupus and hydroxychloroquine"

  • Abstract Number: 1601 • 2017 ACR/ARHP Annual Meeting

    Hydroxychloroquine Non-Adherence Is Associated with Higher Sledai Scores in a Predominantly Hispanic Population

    Alexandra Perel-Winkler1, Kayla Neville1, James Miceli1, Samantha Nguyen1, Miya Okado1, Laura Geraldino-Pardilla1, Teja Kapoor1, Jon T. Giles2 and Anca Askanase1, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Non-adherence to medication has been shown to impact mortality, morbidity, and health care utilization in SLE and ranges from 40-80% depending on the methods…
  • Abstract Number: 744 • 2016 ACR/ARHP Annual Meeting

    Factors Related to Blood Hydroxychloroquine Concentration in Patients with Systemic Lupus Erythematosus

    Ji Yeon Lee1, Jennifer Lee2, Seung-Ki Kwok3, Ji Hyeon Ju4, Kyung-Su Park5 and Sung-Hwan Park4, 1International Healthcare Center, Seoul St Mary's Hosiptal, Seoul, Korea, Republic of, 2Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, 3[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, 4Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, 5Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea, The Republic of

    Background/Purpose:  To identify factors associated with blood concentrations of hydroxychloroquine (HCQ) and its major metabolite, N-desethylhydroxychloroquine (DHCQ), in patients with systemic lupus erythematosus (SLE) receiving…
  • Abstract Number: 779 • 2016 ACR/ARHP Annual Meeting

    Factors Determining Hydroxychloroquine Serum Levels in a Cohort of Chinese Patients with Systemic Lupus Erythematosus

    Chi Chiu Mok1, Ling Yin Ho2 and Paul Jannetto3, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong, 3Director, Toxicology and Drug Monitoring Laboratory, Mayo Clinic, Rochester, MN

    Background/Purpose:  To study the factors determining the hydroxychloroquine (HCQ) serum concentration in a cohort of Chinese patients with systemic lupus erythematosus (SLE). Methods: Consecutive patients…
  • Abstract Number: 929 • 2016 ACR/ARHP Annual Meeting

    Retinal Examinations Among SLE Patients Newly-Initiating Hydroxychloroquine in a U.S. Medicaid SLE Population, 2000-10

    Tzu-Chieh Lin1, CH Feldman2, Hongshu Guan3, Sarah Chen4, Medha Barbhaiya1 and Karen H. Costenbader1, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 4Beth Israel Deaconess Medical Center, Boston, MA

    Background/Purpose: U.S. Medicaid provides medical benefits to low-income people. Although the Federal government establishes guidelines, each state sets vision benefits. The American Academy of Ophthalmology…
  • Abstract Number: 2010 • 2016 ACR/ARHP Annual Meeting

    Predictive Factors of Adherence to Treatment in an International Prospective Study of Blood Hydroxychloroquine Levels in SLE Patients with Flares

    Nathalie Costedoat-Chalumeau1, Frédéric A. Houssiau2, Peter M. Izmirly3, Véronique Le Guern4, Sandra V. Navarra5, Meenakshi Jolly6, Guillermo RUIZ-IRASTORZA7, Eric Hachulla8, Nancy Agmon-Levin9, Yehuda Shoenfeld10, Francesca Dall'Ara11, Jill P. Buyon12, Christophe Deligny13, Ricard Cervera14, Estibaliz Lazaro15, Holy Bezanahary16, Gabriel Baron17, Gaëlle Leroux18, Nathalie Morel4, Jean-Francois Viallard19, Christian Pineau20, Lionel Galicier21, Ronald van Vollenhoven22, Angela Tincani23, Hanh Nguyen24, Guillaume Gondran25, Noel Zahr26, Jacques Pouchot27, Jean Charles Piette28, Michelle Petri29 and David A. Isenberg30, 1Internal Medicine, Cochin University Hospital, Paris, France, 2Rheumatology, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, 3New York University School of Medicine, New York, NY, 4Internal Medicine Department, Cochin Hospital, “René-Descartes Paris V” University, Paris, France, 5Rheumatology, University of Santo Tomas Hospital, Manila, Philippines, 6Rush, Chicago, IL, 7Cruces University Hospital, Barakaldo, Spain, 8Internal Medicine, Lille University Hospital, Lille, France, 9Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Aviv, Israel, 10Zabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel Hashomer, Israel Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel, 11University of Pavia, Pavia, Italy, 12Medicine, New York University School of Medicine, New York, NY, 13Zobda Quitman Hospital, Rheumatology and Internal Medicine, Fort de France, Martinique, 14Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain, 15Centre François Magendie, CHU de Bordeaux, Pessac, France, 16Internal Medicine, University Hospital of Limoges, Limoges, France, 17Hôpital Hôtel Dieu, Paris, France, 18Internal Medicine, Pitié-Salpêtrière University Hospital, Paris, France, 19Internal Medecine, Haut Lévèque Hospital, Bordeaux, France, 20Rheumatology, MUHC, Montreal, QC, Canada, 21Clinical Immunology, St Louis Hospital, Paris, France, 22Amsterdam Rheumatology Center, Amsterdam, Netherlands, 23Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 24Centre of Rheumatology. Medicine., University College of London Hospital, london, United Kingdom, 25Internal Medicine Department, Limoges, France, 26Pitié Salpêtrière, Pharmacological, Pitié Salpêtrière, Paris, France, 27Internal Medicine Department, European Hospital Georges Pompidou, Paris, France, 28Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, 29Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD, 30Centre for Rheumatology, Division of Medicine, University College London, London, United Kingdom

    Background/Purpose: Non-adherence to treatment, a major cause of continued lupus activity and flares, may be difficult to recognize. In this international prospective study, we evaluated…
  • Abstract Number: 1806 • 2015 ACR/ARHP Annual Meeting

    Hydroxychloroquine Serum Levels and Flares of Systemic Lupus Erythematosus: A Longitudinal Cohort Analysis

    Chi Chiu Mok1, Hannah Penn2, Sau Mei Tse1, Loralie Langman2, Kar Li Chan1 and Paul Jannetto3, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 3Director, Toxicology and Drug Monitoring Laboratory, Mayo Clinic, Rochester, MN

    Background/Purpose: To study the relationship between the serum hydroxychloroquine (HCQ) concentration and flares of systemic lupus erythematosus (SLE) in a longitudinal cohort of Chinese patients.Methods:…
  • Abstract Number: 679 • 2014 ACR/ARHP Annual Meeting

    Hydroxychloroquine Dosing and Disease Activity in a Large Multi-Racial Lupus Cohort

    Jennifer M. Grossman1, Megan E. B. Clowse2, Peter M. Izmirly3, Diane L. Kamen4, Alana B. Levine5, Meggan Mackey6, W. Joseph McCune7, Jerry McGwin8, David S. Pisetsky9, Tammy Utset10 and Jinoos Yazdany11, 1Division of Rheumatology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Rheumatology, Duke University Medical Center, Durham, NC, 3Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 4Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 5Rheumatology, Hospital for Special Surgery, New York, NY, 6Autoimmune & Musculoskeletal Disease, The Feinstein Institute, Mahasset, NY, 7Int Med/ Rheum, University of Michigan, Ann Arbor, MI, 8Biostats, UAB, Birmingham, AL, 9Duke University Medical Center, Durham, NC, 10Internal Medicine/Rheumatology, UC Pritzker Schl of Medicine, Chicago, IL, 11Medicine, University of California, San Francisco, San Francisco, CA

    Background/Purpose:   Treatment with hydroxychloroquine (HCQ) is recommended for all patients with lupus nephritis to prevent further damage and reduce disease manifestations. Some studies suggest…
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