ACR Meeting Abstracts

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Abstracts tagged "Lung Disease"

  • Abstract Number: 412 • 2013 ACR/ARHP Annual Meeting

    Clinical Characterization Of Extensive Interstitial Lung Disease In Rheumatoid Arthritis Patients

    Masaomi Yamasaki, Rheumatology, Shin-Yokohama Yamasaki Clinic, Yokohama, Japan

    Background/Purpose: To investigate clinical characteristics of interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients, and to analyze whether high resolutional CT (HRCT) can predict…
  • Abstract Number: 2574 • 2013 ACR/ARHP Annual Meeting

    Early Use of Prostacyclin Therapy Improves Transplant-Free Survival in Patients With Systemic Sclerosis-Related Pulmonary Arterial Hypertension Plus Interstitial Lung Disease

    Elizabeth Volkmann1, Rajan Saggar2, Bryant Torres1, Lynne Yoder2, Robert Elashoff3, Rajeev Saggar4, Harsh Agrawal1, Nabeel Borazan5, Sarah Thomas1 and Daniel Furst1, 1Medicine, University of California, Los Angeles, Los Angeles, CA, 2Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 3Biomath, University of California, Los Angeles, Los Angeles, CA, 4Critical Care Medicine, St. Joseph's Hospital and Medical Center, Phoenix, AZ, 5Medicine, Rheumatology UCLA, Los Angeles, CA

    Background/Purpose: The leading causes of death in systemic sclerosis (SSc) are pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD). Use of PAH therapy in…
  • Abstract Number: 2567 • 2013 ACR/ARHP Annual Meeting

    Cadherin-11 Regulates Pulmonary Fibrosis In Bleomycin-Induced Lung Injury

    Mesias Pedroza, Anuh T. George and Sandeep K. Agarwal, Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX

    Background/Purpose: Pulmonary fibrosis (PF) is the leading cause of death in systemic sclerosis.  Pathologically, PF is characterized by an aberrant wound healing repair mechanism leading…
  • Abstract Number: 2070 • 2013 ACR/ARHP Annual Meeting

    Cytokine Profiles In Polymyositis and Dermatomyositis Complicated With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Associated Interstitial Lung Disease Or Anti-Aminoacyl tRNA Synthetase Antibody-Associated Interstitial Lung Disease

    Takahisa Gono, Yasushi Kawaguchi, Hirotaka Kaneko, Yasuhiro Katsumata, Masanori Hanaoka, Sayuri Kataoka, Hidenaga Kawasumi, Kae Takagi, Hisae Ichida, Sayumi Baba, Yuko Okamoto, Yuko Ota and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: Polymyositis (PM) / dermatomyositis (DM) are often complicated with interstitial lung disease (ILD). In PM/DM, complication with ILD is associated with anti-aminoacyl-tRNA synthetase (ARS),…
  • Abstract Number: 2076 • 2013 ACR/ARHP Annual Meeting

    Oxidation Products Of Arachidonic Acid and Linoleic Acid Are Increased In High Density Lipoprotein From Patients With Dermatomyositis and Polymyositis

    Christina Charles-Schoeman1, Yuen Yin Lee1, Ani Shahbazian1, David Meriwether2, Geraldine Navarro1, John D. FitzGerald1 and Srinivasa T. Reddy2, 1Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Medicine-Cardiology, UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose:   Oxidation products of arachidonic acid and linoleic acid including hydroxyeicosatetraenoic acids (HETEs) and hydroxyoctadecadienoic acids (HODEs), respectively, play an important role in the…
  • Abstract Number: 2077 • 2013 ACR/ARHP Annual Meeting

    Inflammatory Lung Disease a Potential Risk Factor For Onset Of Inflammatory Myopathies

    Ingrid E. Lundberg1, Sevim Barbasso Helmers2 and Lars Alfredsson3, 1Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, 2Institute of Environmental Medicine, Unit of Cardiovascular Epidemiology, Karolinska Institutet, Stockholm, Sweden, 3Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Although the etiology of inflammatory myopathies is unclear, there are data indicating that myositis occurs as a result of complex interactions between genes and…
  • Abstract Number: 2079 • 2013 ACR/ARHP Annual Meeting

    Serum Interferon α, β and Interleukin-18 Are Associated With Disease Activity Of Rapidly Progressive Interstitial Lung Disease In Patients With Clinical Amyopathic Dermatomyositis

    Shinji Sato1, Noriko Sasaki1, Shinichi Nogi1, Naofumi Chinen2, Kiri Honda1, Eiko Saito1, Chiho Yamada2 and Yasuo Suzuki2, 1Rheumatology, Tokai University School of Medicine, Isehara, Japan, 2Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan

    Background/Purpose: It is well known that rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM) is associated with poor outcome. Previous findings suggested…
  • Abstract Number: 2053 • 2013 ACR/ARHP Annual Meeting

    Efficacy Of Intermittent Intra-Venous Cyclophosphamide and Cyclosporin A Combination Therapy For Rapidly Progressive Interstitial Lung Disease With Dermatomyositis Associated With Anti-Melanoma Differentiation-Associated Gene 5 Autoantibody Titer

    Noriko Sasaki1, Shinji Sato1, Shinichi Nogi1, Naofumi Chinen2, Kiri Honda1, Eiko Saito1, Chiho Yamada2 and Yasuo Suzuki2, 1Rheumatology, Tokai University School of Medicine, Isehara, Japan, 2Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan

    Background/Purpose: Anti-Melanoma Differentiation-Associated Gene 5 (MDA5) autoantibody is present specifically in patients with dermatomyositis (DM), especially those with few or no muscle manifestations (clinically amyopathic…
  • Abstract Number: 922 • 2013 ACR/ARHP Annual Meeting

    Role Of B Cells and/Or Autoantibodies In Pulmonary Manifestations Of Inflammatory Arthritis

    Lisa K. Peterson1, Jeremy Sokolove2, Paul Jedlicka3, Lauren J. Lahey4, William H. Robinson5 and Leonard L. Dragone6, 1Pediatrics, National Jewish Health, Denver, CO, 2VA Palo Alto Healthcare System and Stanford University, Palo Alto, CA, 3Pathology, University of Colorado Denver, Aurora, CO, 4Medicine, VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, 5VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, 6Dept of Pediatrics, National Jewish Health, Denver, CO

    Background/Purpose: RA is a systemic condition affecting approximately 1% of the general population leading to progressive arthritis and extra-articular manifestations (ExRA), including interstitial lung disease…
  • Abstract Number: 926 • 2013 ACR/ARHP Annual Meeting

    Autoantibodies to the Th/To Complex Are the Most Common Antibodies in Systemic Sclerosis (SSc) Patients Without Other Autoantibodies

    Michael Mahler1, Jason Y.F. Chan2, Edward K.L. Chan3, Minoru Satoh2, Marie Hudson4, Murray Baron5, James Wick6 and Marvin J. Fritzler7, 1Research, INOVA Diagnostics, San Diego, CA, 2Medicine, University of Florida, Gainesville, FL, 3Oral Biology, University of Florida, Gainesville, FL, 4Jewish General Hospital, McGill University, Montreal, QC, Canada, 5Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, 6Department of medicine, Faculty of Medicine, University of Calgary, Calgary, AB, Canada, 7Medicine, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Antinuclear antibodies (ANA) play an important role in the diagnosis of systemic sclerosis (SSc) being present in about 80-90% of the patients. In the…
  • Abstract Number: 697 • 2013 ACR/ARHP Annual Meeting

    Longitudinal Assessment Of Pulmonary Function In 304 Norwegian Patients With Systemic Sclerosis

    Anna-Maria Hoffmann-Vold1, Torhild Garen2, Oyvind Midtvedt1, May-Brit Lund3, Jan Tore Gran1 and Øyvind Molberg4, 1Rheumatology, Oslo University Hospital, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 3Pulmonary Unit, Oslo University Hospital, Rikshopitalet, Oslo, Norway, 4Oslo University Hospital, Oslo, Norway

    Background/Purpose: The purpose of this study was to asses sequential pulmonary function measurements (forced vital capacity [FVC] % predicted) in a large systemic sclerosis (SSc)…
  • Abstract Number: 666 • 2013 ACR/ARHP Annual Meeting

    Involvement Of TCR Vdelta1+ NKT Cells In Systemic Sclerosis: Association With Interstitial Pneumonia

    Seiji Segawa1, Daisuke Goto2, Masanobu Horikoshi2, Yuya Kondo3, Naoto Umeda2, Shinya Hagiwara2, Masahiro Yokosawa4, Tomoya Hirota3, Haruka Miki1, Hiroto Tsuboi3, Hiroshi Ogishima2, Takeshi Suzuki4, Isao Matsumoto5 and Takayuki Sumida3, 1Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan, 2Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba City, Japan, 3Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, 4Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, 5Department of Internal Medicine, Faculty of Medicine,, University of Tsukuba, Tsukuba, Japan

    Background/Purpose: Interstitial pneumonia (IP) is one of the critical complications in patients with several autoimmune diseases. However, the exact mechanism of IP remains elusive. Recently,…
  • Abstract Number: 675 • 2013 ACR/ARHP Annual Meeting

    Impact Of Male Sex On Survival In Systemic Sclerosis

    Haseena Hussein1, Peter Lee2, Cathy Chau3 and Sindhu R. Johnson4, 1Medicine, Toronto Scleroderma Research Program, Mount Sinai Hospital, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Lebovic Bldg, Mt. Sinai Hospital, Toronto, ON, Canada, 3Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 4Medicine, Division of Rheumatology, Toronto Western Hospital, University Health Network Pulmonary Hypertension Programme, Toronto General Hospital, Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Systemic sclerosis (SSc) has a female predominance with a female-to-male ratio of 3:1. Sex differences have been seen in many autoimmune diseases; however, little…
  • Abstract Number: 648 • 2013 ACR/ARHP Annual Meeting

    A Possible Contribution of Inducible Costimulator to the Development of Skin Sclerosis and Interstitial Lung Disease in Systemic Sclerosis

    Koichi Yanaba1, Yoshihide Asano2 and Shinichi Sato2, 1Dermatology, The University of Tokyo, Tokyo, Japan, 2Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan

    Background/Purpose: Systemic sclerosis (SSc) is a heterogeneous disorder characterized by excessive fibrosis and microvascular damage of the skin and various internal organs. Cutaneous mononuclear cell…
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