ACR Meeting Abstracts

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Abstracts tagged "lung and rheumatoid arthritis"

  • Abstract Number: 2560 • 2016 ACR/ARHP Annual Meeting

    Sputum Antibody to Malondialdehyde-Acetaldehyde Adduct in Subjects with Established Rheumatoid Arthritis

    Bryant R. England1,2, Peter Maloley3, Eric Daubach3, Michael J. Duryee4, M. Kristen Demoruelle5, Kevin D. Deane5, Geoffrey M. Thiele6 and Ted R Mikuls6, 1Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 2VA Nebraska-Western Iowa, Omaha, NE, 3University of Nebraska Medical Center, Omaha, NE, 4Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 5Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 6Veteran Affairs Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Anti-malondialdehyde-acetaldehyde adduct (MAA) antibodies target immunogenic products of oxidative stress, are detected in higher concentration in paired synovial fluid vs serum in RA, and…
  • Abstract Number: 3017 • 2016 ACR/ARHP Annual Meeting

    Elevated Neutrophil Extracellular Trap Levels Correlate with Anti-CCP3-IgG and Anti-CCP3-IgA Levels in the Sputum of Individuals at-Risk for Future Rheumatoid Arthritis

    M. Kristen Demoruelle1, Monica Purmalek2, Heather Rothfuss3, Michael Weisman4, Lindsay Kelmenson1, Michael Mahler5, Jill M. Norris6, Brian Cherrington3, Mariana Kaplan2, V. Michael Holers1 and Kevin D. Deane1, 1Rheumatology Division, University of Colorado Denver, Aurora, CO, 2Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 3Zoology and Physiology, University of Wyoming, Laramie, WY, 4Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 5Research and Development, Inova Diagnostics, San Diego, CA, 6Epidemiology, Colorado School of Public Health, Aurora, CO

    Background/Purpose: The initial site of anti-citrullinated protein antibody (ACPA) generation in RA has been proposed to be a mucosal site. We have previously demonstrated ACPA…
  • Abstract Number: 3019 • 2016 ACR/ARHP Annual Meeting

    Sputum Antibodies to Individual Citrullinated Protein/Peptide Antigens Are Elevated in Subjects at-Risk of Future RA and Subjects with Established Disease

    Emily Bowers1, M. Kristen Demoruelle2, Michael Weisman3, Jill M. Norris4, William H. Robinson5, V. Michael Holers2 and Kevin D. Deane2, 1Medicine, University of Colorado Denver, Aurora, CO, 2Rheumatology Division, University of Colorado Denver, Aurora, CO, 3Cedars-Sinai Medical Center, Los Angeles, CA, 4Epidemiology, Colorado School of Public Health, Aurora, CO, 5Stanford University School of Medicine, Stanford, CA

    Background/Purpose: Multiple studies demonstrate that ACPAs are elevated in the serum years prior to the onset of seropositive RA during a preclinical period of autoimmunity.…
  • Abstract Number: 2659 • 2012 ACR/ARHP Annual Meeting

    An Expanded Repertoire of Anti-Citrullinated Peptide Antibodies Is Associated with Interstitial Lung Disease in Rheumatoid Arthritis

    Jon T. Giles1, Sonye Danoff2, Jeremy Sokolove3, Robert Winchester4, Dimitrios A. Pappas5, Catriona Cramb6, Geoffrey Connors7, Stanley S. Siegelman8, William H. Robinson9 and Joan M. Bathon5, 1Medicine, Columbia University, New York, NY, 2Medicine/Pulmonary, Johns Hopkins School of Medicine, Baltimore, MD, 3Medicine, VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, 4Dept of Medicine & Pathology, Columbia University, New York, NY, 5Columbia University, New York, NY, 6VA Palo Alto Heatlh Care System and Stanford University, Palo Alto, CA, 7Division of Pulmonary and Critical Care Medicine, Yale University, New Haven, CT, 8Department of Radiology, Johns Hopkins University, Baltimore, MD, 9Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA

    Background/Purpose: Interstitial lung disease (ILD) is an outcome with high morbidity and mortality in rheumatoid arthritis (RA).  Citrullinated proteins are observed in these lung tissues;…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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