ACR Meeting Abstracts

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Abstracts tagged "longitudinal studies"

  • Abstract Number: 2571 • ACR Convergence 2024

    Trajectories of Physical Function in Children with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Clare Cunningham1, Roberta A Berard2, Matthew Berkowitz3, Brian Feldman4, Nicole Johnson5, Lillian Lim6, Thomas Loughin3, Meghan McPherson7, Paivi Miettunen5, Jean-Philippe Proulx-Gauthier8, Dax Rumsey6, Heinrike Schmeling5, Lori Tucker9, Kristin Houghton10 and Jaime Guzman11, and CAPRI Registry Investigators, 1University of British Columbia, Vancouver, BC, Canada, 2London Health Sciences Centre, London, ON, Canada, 3Simon Fraser University, Burnaby, BC, Canada, 4Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 5University of Calgary, Calgary, AB, Canada, 6University of Alberta, Edmonton, AB, Canada, 7University of Manitoba, Winnipeg, MB, Canada, 8CHU de Quebec - Universite Laval, Quebec, QC, Canada, 9BC Children's Hospital, Vancouver, BC, Canada, 10University of British Columbia - Vancouver, Vancouver, BC, Canada, 11University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood. Contrary to historical cohorts, it is hoped that with contemporary treatments…
  • Abstract Number: 0175 • ACR Convergence 2024

    Do Knee Strength and Pain Relate to Developing Stair Climbing Difficulty for Knee Osteoarthritis?

    Jason Jakiela1, Yvonne Golightly2, Sydney Liles3, Judy Foxworth4 and Daniel White5, 1Winston-Salem State University, Winston-Salem, NC, 2University of Nebraska Medical Center, Omaha, NE, 3University of Delaware, Elkton, MD, 4Winston-Salem State University, Elon, NC, 5University of Delaware, Newark, DE

    Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and stair climbing difficulty is often the first-reported limitation. Previous work…
  • Abstract Number: 1541 • ACR Convergence 2024

    Effect of Rituximab on Long-term Damage Acquisition in Patients with Systemic Lupus Erythematosus

    Amanda Brito1, Teresa Moitinho de Almeida2, Sofia Miranda3, Miriam Barreto Baié1, Daniel Calado3 and David Isenberg4, 1Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil, 2Unidade Local de Saúde de Lisboa Ocidental, Lisboa, Portugal, 3Hospital do Divino Espírito Santo, Ponta Delgada, Portugal, 4University College London, London, United Kingdom

    Background/Purpose: B-cell depletion has been used to treat patients with systemic lupus erythematosus (SLE) for over twenty years, but we still lack studies that evaluate…
  • Abstract Number: 0638 • ACR Convergence 2024

    Soluble TNF RII in Lupus Nephritis as a Biomarker of Disease Activity and Treatment Response

    Ranjan Gupta1, Sonam Rajput2, Jayanth Kumar2 and Dipendra K Mitra2, 1All India Institute of Medical Sciences, New Delhi, Delhi, India, 2All India Institute of Medical Sciences, New Delhi, New Delhi, India

    Background/Purpose: Lupus Nephritis (LN) affects almost 60-70% patients of Systemic Lupus Erythematosus (SLE). Conventional markers of renal involvement i.e. proteinuria and renal biopsy have limitations…
  • Abstract Number: 1870 • ACR Convergence 2024

    Costs and Healthcare Resource Utilization Associated with Inpatient and Day Hospitalizations of Patients with Lupus and Psychiatric Manifestations in France

    Nicoleta Petrica1, Nathan Cohen1, Maria Pini1, Minjee Park2, Mathieu Rosé3 and Jean-Francois Ricci2, 1Alira Health, Paris, France, 2Alira Health, Basel, Switzerland, 3Alira Health, Barcelone, Spain

    Background/Purpose: Lupus, a rare chronic autoimmune disorder, severely impacts patients' quality of life, productivity, and survival, placing a heavy burden on the healthcare system. Up…
  • Abstract Number: 0688 • ACR Convergence 2024

    Mycophenolate Mofetil Treatment in Limited Cutaneous Systemic Sclerosis Reduces the Risk of Vascular Complication Leading to Treatment Escalation: Emulation of a Target Trial Using Time-dependent Propensity Score-matching

    Enrico De Lorenzis1, Gerlando Natalello2, Fabio Cacciapaglia3, Rossella De Angelis4, Edoardo Cipolletta5, Veronica Codullo6, Giacomo De Luca7, Dilia Giuggioli8, Francesca Ingegnoli9, Valeria Riccieri10, Maria Antonietta D'Agostino11, Clodoveo Ferri12, Marco Matucci Cerinic13 and Silvia Laura Bosello14, 1Catholic University of the Sacred Heart, Roma, Rome, Italy, 2Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, 3Rheumatology Unit � DiMePRe-J, University and AOU Policlinico of Bari, Italy, Bari, Italy, 4Polytechnic University of Marche, Ancona, Italy, Ancona, Italy, 5Polytechnic University of Marche, Ancona, Italy, 6Division of Rheumatology - Policlinico San Matteo, Pavia, Italy, Pavia, Lombardia, Italy, 7Vita-Salute San Raffaele University & IRCCS San Raffaele Hospital, Milan, Milan, Italy, 8Scleroderma Unit, University of Modena and Reggio Emilia, Modena, Italy, 9Division of Clinical Rheumatology, ASST Pini, Dept. of Clinical Sciences & Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Research Center for Environmental Health, Università degli Studi di Milano, Milan, Italy, 10Department of Rheumatology, La Sapienza University of Rome, Rome, Italy, 11Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy, 12Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy, 13Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, 14Unit of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy

    Background/Purpose: The prescription of Mycophenolate Mofetil (MMF) represents the primary treatment for interstitial lung disease (ILD) associated with systemic sclerosis (SSc) and is an option…
  • Abstract Number: 1871 • ACR Convergence 2024

    A Seropositive RA Polygenic Risk Score Does Not Predict Progression to RA in an ACPA Positive Population

    Tada Vargas1, Lauren Vanderlinden2, Patrick Carry3, Kristen Demoruelle4, Marie Feser1, Katerina Kechris5, Jane Buckner6, William Robinson7, Gary Firestein8, Michael Holers1, Kevin Deane9 and Jill Norris10, 1Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 2Colorado School of Public Health, Monument, CO, 3Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, 4University of Colorado Anschutz Medical Campus, Golden, CO, 5Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, 6Benaroya Research Institute, Seattle, WA, 7Division of Immunology and Rheumatology, Stanford University, and VA Palo Alto Health Care System, Stanford, CA, 8University of California, San Diego, San Diego, CA, 9University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 10Colorado School of Public Health, Denver, CO

    Background/Purpose: Serum autoantibodies, such as ACPA and RF, are commonly detectable prior to the development of seropositive clinical RA; however, not all individuals with these…
  • Abstract Number: 0711 • ACR Convergence 2024

    Molecular Signatures in the Skin as Predictors of Longitudinal Clinical Trajectories in Patients with Systemic Sclerosis

    Natania Field1, Monica Yang2, Niket Gupta1, Maxwell Shramuk1, Lutfiyya Muhammad1, Vivien Goh1, Monica Espinoza3, Yiwei Yuan3, Rezvan Parvizi3, Kathleen Aren4, Mary Carns4, Isaac Goldberg5, Lorinda Chung6, Dinesh Khanna7, Zsuzsanna McMahan8, Michael Whitfield3 and Monique Hinchcliff9, 1Northwestern Feinberg School of Medicine, Chicago, IL, 2UCSF, San Francisco, CA, 3Geisel School of Medicine at Dartmouth, Hanover, NH, 4Northwestern University Division of Rheumatology, Chicago, IL, 5Wayne State University School of Medicine, Detroit, MI, 6Stanford University, Woodside, CA, 7University of Michigan, Ann Arbor, MI, 8UTHealth Houston Division of Rheumatology, Houston, TX, 9Yale School of Medicine, Westport, CT

    Background/Purpose: It has become clear that classification by phenotype is insufficient to explain the heterogeneity in clinical progression for many rheumatic diseases. Systemic sclerosis (SSc)…
  • Abstract Number: 1953 • ACR Convergence 2024

    The National Trend of Using Prescription Immunosuppressives

    Queeneth Edwards1, Amenah Qotineh1, Chukwuemelie Okeke2 and Jian Zhang1, 1Georgia Southern University, statesboro, GA, 2St Georges University, St Georges, Saint George, Grenada

    Background/Purpose:  Recent data from the 2021 National Health Interview Survey (NHIS) reveals a marked increase in the percentage of adults using immunosuppression. However, data from…
  • Abstract Number: 0822 • ACR Convergence 2024

    Investigating the Association Between Alcohol Consumption and Spinal Radiographic Progression in Axial Spondyloarthritis: A Longitudinal Cohort Analysis over a Period of 6 Years

    Evelyne Gendron1, Sinead Maguire2, Yangqing Deng3, Nigil Haroon4 and Robert Inman5, 1University of Toronto, University Health Network, Schroeder Arthritis Institute, Department of Rheumatology, Quebec City, QC, Canada, 2University of Toronto, University Health Network, Schroeder Arthritis Institute, Department of Rheumatology, Toronto, Canada, 3Department of Biostatistics, University Health Network, Toronto, Canada, 4Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto, Toronto, ON, Canada, 5University Health Network, Toronto, ON, Canada

    Background/Purpose: We assessed whether alcohol consumption (AC) is associated with spinal radiographic progression in axSpA as measured by the modified Stoke Ankylosing Spondylitis Spinal Score…
  • Abstract Number: 2048 • ACR Convergence 2024

    Prognostic Value of Bronchoalveolar Lavage in CTD-related Interstitial Lung Disease: An Observational Study

    Maximilian Gysan1, Svitlana Pochepnia2, Helmut Prosch2, Antje Lehmann1, Silvia Lee1, Andreas Renner1, Daniela Gompelmann3, Marco Idzko1, Iris Aykara4, Karolina Anderle4, Peter Weber4, Hans Kiener4, Michael Bonelli4, Daniel Mrak4, Daniel Aletaha5, Helga Lechner-Radner4 and Kastriot Kastrati4, 1Division of Pulmonology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 2Division of General and Paediatric Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 3Division of Pulmonology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria., Vienna, Austria, 4Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 5Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Wien, Austria

    Background/Purpose: The prognostic value of bronchoalveolar lavage (BAL) in connective tissue disease-related interstitial lung disease (CTD-ILD) is currently underexplored, resulting in a lack of understanding…
  • Abstract Number: 0864 • ACR Convergence 2024

    Obesity Subtypes and Trajectories of Functional Change After 7-years of Follow-up: The Multicenter Osteoarthritis (MOST) Study

    Kristine Godziuk1, Sarah Tilley2, mike LaValley3, Michael Nevitt4, C.E. Lewis5, James Torner6 and Tuhina Neogi2, 1University of Alberta, Edmonton, AB, Canada, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3Boston University School of Public Health, Arlington, MA, 4UCSF, Orinda, CA, 5University of Alabama at Birmingham, Birmingham, AL, 6University of Iowa, Iowa City

    Background/Purpose: People with knee osteoarthritis (OA) and obesity (i.e. BMI ≥30kg/m2) have poorer function than those without obesity. However, function is not uniform among people…
  • Abstract Number: 2102 • ACR Convergence 2024

    Unraveling Knee Osteoarthritis Subtypes: Differential Effect of Oral Salmon Calcitonin Treatment

    Monica Hannani1, Peder Frederiksen2, Morten Karsdal2, Asger Reinstrup Bihlet3, Jaume Bacardit4, Anne-Christine Bay-Jensen2 and Christian Thudium2, 1Nordic Bioscience & University of Copenhagen, Herlev, Denmark, 2Nordic Bioscience, Herlev, Denmark, 3NBCD A/S, Soeborg, Denmark, 4School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom

    Background/Purpose: Osteoarthritis (OA) patients are to this day left without effective treatment options. Despite different etiologies, trials designs do not account for the substantial heterogeneity…
  • Abstract Number: 0886 • ACR Convergence 2024

    A Longitudinal Cohort Study Uncovers Plasma Protein Biomarkers Predating Clinical Onset and Treatment Response of Rheumatoid Arthritis

    Chenxi Zhu1, Siyu He2, Yi Liu3, Rui Sun1 and Yi Zhao4, 1Department of Rheumatology and Immunology, West China Hospital,Sichuan University, Chengdu, Sichuan, China, chengdu, China (People's Republic), 2West China Hospital Sichuan University, chengdu, China (People's Republic), 3Department of Rheumatology and Immunology, West China Hospital,Sichuan University, Chengdu, Sichuan, China, chengdu, 4Department of Rheumatology and Immunology, West China Hospital,Sichuan University, Chengdu, Sichuan, China, Sichuan, China (People's Republic)

    Background/Purpose: Rheumatoid arthritis (RA) is a complex systemic inflammatory autoimmune disease with a high incidence, primarily affecting the joints. However, it currently lacks definitive biomarkers…
  • Abstract Number: 2182 • ACR Convergence 2024

    PECOS (Pediatric SARS-CoV-2 MIS-C Long-term Outcomes Study): Preliminary Results

    Gina Montealegre Sanchez1, Lauren Arrigoni2, Kevin Rubenstein3, Max Wolff4, Mallory Barrix2, C. Jason Liang5, James Bost6, Meghan Delaney7, Luigi Notarangelo8, Karyl Barron9 and Roberta DeBiasi10, and PECOS Study Team, 1Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID),National Institutes of Health (NIH), Bethesda, MD, 2Center for Cancer and Immunology Research (CCIR), Children's National Research Institute, Washington, DC, 3Clinical Monitoring Research Program Directorate (CMRPD), National Cancer Institute Frederick National Laboratory for Cancer Research, Frederick, MD, 4Clinical Research Directorate (CRD), National Cancer Institute Frederick National Laboratory for Cancer Research, Frederick, MD, 5Biostatistics Research Branch, NIAID, NIH, Bethesda, MD, 6Division of Biostatistics and Study Methodology and Center for Translational Research, Children's National Research Institute, Washington, DC, 7Department of Pathology and Laboratory Medicine, Children's National Hospital, Washington, DC, 8Laboratory of Clinical Immunology and Microbiology (LCIM), NIAID, Bethesda, MD, 9Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 10Children's National Hospital and Research Institute, Washington, DC

    Background/Purpose: The long-term sequelae of SARS-CoV-2 infection in children are unknown. PECOS is a large prospective observational cohort study with the main objective to characterize…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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