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Abstracts tagged "longitudinal studies"

  • Abstract Number: 2966 • 2018 ACR/ARHP Annual Meeting

    Ultrasound Shows Rapid Reduction of Uric Load during Treat-to-Target Approach in Gout Patients: Results from a Longitudinal Study

    Hilde B Hammer1, Lars Fritjof Karoliussen2, Lene Terslev3, Espen A. Haavardsholm1, Tore Kvien4 and Till Uhlig5, 1Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Rheumatology, Rigshospitalet Glostrup, Copenhagen, Denmark, 4RAID working group for EULAR, Zurich, Switzerland, 5Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose:  Uric monosodium urate (MSU) depositions are detected by ultrasound (US), and US is included in the ACR/EULAR classification criteria for gout. OMERACT definitions for…
  • Abstract Number: 240 • 2018 ACR/ARHP Annual Meeting

    Bi-Directional Associations between “Too Much Sitting” and Self-Reported Pain in Patients with Rheumatoid Arthritis

    Ciara O'Brien1, Joan L. Duda1, Jet J.C.S. Veldhuijzen van Zanten1,2, George S. Metsios2,3, George D. Kitas1,2,4 and Sally A.M. Fenton1,2, 1School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom, 2Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, 3Faculty of Education Health & Wellbeing, University of Wolverhampton, Walsall, United Kingdom, 4Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom

    Background/Purpose: Epidemiological evidence indicates that sedentary behaviour, or “too much sitting”, is associated with poor health outcomes in the general population, including elevated systemic inflammation.…
  • Abstract Number: 455 • 2018 ACR/ARHP Annual Meeting

    Metabolic Syndrome and Trajectories of Pain Severity and Number of Painful Sites in Knee Osteoarthritis: Data from a 10.7-Year Prospective Study

    Feng Pan1, Jing Tian2, Flavia Cicuttini3 and Graeme Jones4, 1Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 2Public health unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 3Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, 4Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: Metabolic syndrome (MetS) has been suggested as having a role in osteoarthritis (OA) pathogenesis. No study has assessed whether MetS and its components are…
  • Abstract Number: 784 • 2017 ACR/ARHP Annual Meeting

    Damage and Predictors of Damage in Takayasu’s Arteritis

    Antoine G. Sreih1, Tanaz A. Kermani2, David Cuthbertson3, Simon Carette4, Nader A. Khalidi5, Curry L. Koening6, Carol A. Langford7, Carol A. McAlear8, Paul A. Monach9, Larry W. Moreland10, Christian Pagnoux11, Philip Seo12, Kenneth J. Warrington13, Steven R. Ytterberg13 and Peter A. Merkel1,14, 1Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Division of Rheumatology, University of California, Los Angeles, CA, 3Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 4Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 5Rheumatology, McMaster University, Hamilton, ON, Canada, 6Rheumatology, University of Utah, Salt Lake City, UT, 7Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 8University of Pennsylvania, Philadelphia, PA, 9Boston University School of Medicine, Boston, MA, 10Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 11Rheumatology-Vasculitis clinic, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 12Medicine, Johns Hopkins University, Baltimore, MD, 13Rheumatology, Mayo Clinic, Rochester, MN, 14Biostatistics, Epidemiology, and Bioinformatics, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Information regarding the degree and the predictors of damage in patients with Takayasu’s arteritis (TAK) is limited. This study aimed to characterize damage and…
  • Abstract Number: 943 • 2017 ACR/ARHP Annual Meeting

    The Course of the Forced Vital Capacity during Treatment for Systemic Sclerosis-Related Interstitial Lung Disease Predicts Long-Term Survival in 2 Independent Cohorts

    Elizabeth R. Volkmann1, Donald P. Tashkin1, Myung Sim1, Dinesh Khanna2, Michael Roth3, Philip J. Clements3, Daniel E. Furst1, Lynette Keyes-Elstein4, Ashley Pinckney4, Ellen Goldmuntz5, Robert Elashoff6 and Keith Sullivan7, 1University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2University of Michigan, Ann Arbor, MI, 3Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 4Rho Federal Systems, Inc., Chapel Hill, NC, 5NIAID, NIH, Bethesda, MD, 6University of California, Los Angeles, Los Angeles, CA, 7Duke University, Durham, NC

    Background/Purpose: While prior observational studies have identified predictors of mortality in systemic sclerosis-interstitial lung disease (SSc-ILD), no studies have evaluated predictors of long-term mortality in…
  • Abstract Number: 1248 • 2017 ACR/ARHP Annual Meeting

    Evaluation of Validated Patient Reported Outcome Measures to Assess Sensitivity to Change in Patients with Systemic Sclerosis and Gastroesophageal Reflux Disease —a Scleroderma Clinical Trials Consortium Collaborative Project

    Zsuzsanna McMahan1, Tracy M. Frech2, David Lim3, Veronica J. Berrocal4, Cosimo Bruni5, Marco Matucci-Cerinic6, Vanessa Smith7, Karin Melsons8, Susanna Proudman9, Jinyu Zhang10, Fabian A Mendoza11, Melanie Woods3 and Dinesh Khanna3, 1Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, 2Division of Rheumatology, University of Utah, Salt Lake City, UT, 3University of Michigan, Ann Arbor, MI, 4Div of Rheumatology, University of Michigan, Ann Arbor, MI, 5Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy, 6Dept of Medicine/Div of Rheum, University of Florence, Firenze, Italy, 7Faculty of Internal Medicine, Ghent University, Ghent, Belgium, 8Ghent University, Gent, Belgium, 9Discipline of Medicine, University of Adelaide, Adelaide, Australia, 10Thomas Jefferson University, Philadelphia, PA, 11Jefferson Institute of Molecular Medicine and Scleroderma Center, Rheumatology Division, Department of Medicine, Thomas Jefferson University, Philadelphia, PA

    Background/Purpose: The UCLA SCTC GIT 2.0 and NIH PROMIS GI Symptoms Scales are validated in scleroderma to assess patient-reported gastrointestinal (GI) involvement. We sought to…
  • Abstract Number: 1277 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Predictors of Physical Function in Juvenile Myositis

    Kaveh Ardalan1,2, Hannah L. Palac3,4, Julia (Jungwha) Lee4, Madison Wolfe5,6, Gabrielle A. Morgan7,8 and Lauren M. Pachman9, 1Departments of Pediatrics and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Division of Rheumatology, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, 3Abbvie, Inc, Chicago, IL, 4Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 6Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 7Cure JM Program of Excellence in Myositis Research, Chicago, IL, 8Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 9Cure JM Program of Excellence in Juvenile Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL

    Background/Purpose: Juvenile myositis (JM) is marked by skin rashes, proximal muscle weakness, and deconditioning causing potentially severe disability. Studies examining long-term physical function in JM…
  • Abstract Number: 1500 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Analysis of Different Therapeutic Strategies in Patients with Primary Sjögren’s Syndrome

    Kristen Davies1, Kamran Mirza1, Jessica Tarn2, Marian Regan3, Saravanan Vadivelu4, Gavin Clunie5, Jacqueline Andrews6, Elizabeth Price7, Steve Young-Min8, Ian Giles9, Bhaskar Dasgupta10, Cathy Lawson11, Nagui Gendi12, Neil J. McHugh13, Michele Bombardieri14, Costantino Pitzalis14, Nurhan Sutcliffe14, Simon Bowman15, Dennis Lendrem16,17 and Wan-Fai Ng2,18, 1Institute of Cellular Medicine, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, 2Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, 3Royal Derby Hospital, Derby, UK, Derby, United Kingdom, 4Queen Elizabeth Hospital, Gateshead, UK, Gateshead, United Kingdom, 5Ipswich Hospital NHS Trust, Ipswich, UK, Ipswich, United Kingdom, 6Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, 7Great Western Hospital, Swindon, UK, Swindon, United Kingdom, 8Queen Alexander Hospital, Portsmouth, UK, Portsmouth, United Kingdom, 9Centre for Rheumatology, University College London, Centre for Rheumatology, University College London, UK, London, United Kingdom, 10Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Westcliff-on-Sea, United Kingdom, 11Harrogate District Hospital, Harrogate, UK, Harrogate, United Kingdom, 12Basildon and Thurrock University Hospital, Basildon, UK, Basildon, United Kingdom, 13Royal National Hospital for Rheumatic Diseases, Bath, UK, Bath, United Kingdom, 14Barts Health NHS Trust & Barts and the London School of Medicine & Dentistry, London, UK, London, United Kingdom, 15Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, Birmingham, United Kingdom, 16Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-upon-Tyne, United Kingdom, 17Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle, United Kingdom, 18Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom

    Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease characterised by sicca features and systemic manifestations such as pain and fatigue. The classic…
  • Abstract Number: 1613 • 2017 ACR/ARHP Annual Meeting

    Natural History of Disease Activity and Damage in Patients with Cutaneous Lupus Erythematosus on Standard of Care Treatments Using Longitudinal Registries from Two Academic Dermatology Centers

    Noelle M. Teske1, Khor Jia Ker2,3, Rui Feng4, Benjamin F. Chong1 and Victoria P Werth5, 1Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 2Dermatology, National Skin Centre, Singapore, Singapore, 3Dermatology, University of Pennsylvania, Philadelphia, PA, 4Department of Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania, Philadelphia, PA, 5University of Pennsylvania and the VA Medical Center, Philadelphia, PA

    Background/Purpose: The natural disease course of patients with cutaneous lupus erythematosus (CLE) on standard-of-care treatments is not fully characterized. We sought to characterize their disease…
  • Abstract Number: 1642 • 2017 ACR/ARHP Annual Meeting

    Role of Plaque in Predicting Cardiovascular Events in Women with Lupus over a 20 Year Followup

    Erika Joyce1, Linda Santelices2, Jennifer Mall2, Kristy Huysman2, Amy Xiaoqin Tang3, Michael Anderson2, Jennifer Elliott4, Amy H. Kao5,6 and Susan Manzi2, 1Internal Medicine, Allegheny Health Network, Pittsburgh, PA, 2Medicine, Allegheny Health Network, Pittsburgh, PA, 3Lupus Center of Excellence, Allegheny Health Network Research Institute, Pittsburgh, PA, 4Allegheny Health Network, Pittsburgh, PA, 5EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 6EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA), Billerica, MA

    Background/Purpose: The increased risk of premature cardiovascular disease (CVD) in systemic lupus erythematosus (SLE) patients has been well reported. Multiple series have demonstrated a higher…
  • Abstract Number: 1668 • 2017 ACR/ARHP Annual Meeting

    Identification of a Serum Measure of Lupus Nephritis Activity That Detects Molecular Pathways and Mechanisms Implicated in Renal Damage

    Mikhail Olferiev1, Dina Greenman2, David Fernandez1, Kerry Merritt1, Kyriakos A. Kirou1 and Mary K. Crow3, 1Hospital for Special Surgery, New York, NY, 2Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, NY, 3Department of Medicine, Hospital for Special Surgery, New York, NY

    Background/Purpose: Up to 60% of SLE patients develop renal involvement, and renal injury is an important predictor of mortality in patients with SLE. Kidney biopsy…
  • Abstract Number: 2131 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Cohort Study of Anti-PM/Scl Myositis Patients: Mild Muscle and Lung Involvement with Prominent Perivascular Inflammation

    Rebecca De Lorenzo1, Iago Pinal-Fernandez2, Maria Casal-Dominguez2, Wilson Huang2, Jose Cesar Milisenda1, Cassie Parks2, Katherine Pak3, Cheilonda Johnson4, Eleni Tiniakou5, Jemima Albayda6, Julie J. Paik6, Sonye K. Danoff7, Lisa Christopher-Stine7, Andrea Corse8 and Andrew Mammen3,9, 1Muscle Disease Unit, NIAMS, NIH, Bethesda, MD, 2NIAMS, NIH, Bethesda, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4Medicine/Pulmonology, Johns Hopkins University School of Medicine, Baltimore, MD, 5Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 6Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 7Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 8Neurology, Johns Hopkins University, Baltimore, MD, 9Neurology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: To describe the clinical and serologic features, as well as the disease course and response to therapy of anti-PM/Scl patients. Methods: All Johns Hopkins…
  • Abstract Number: 2138 • 2017 ACR/ARHP Annual Meeting

    Predictive Factors for Achievement of Sustained Remission with Polymyositis/Dermatomyositis: A Retrospective Single Center Cohort Study in Japan

    Eri Watanabe1, Takahisa gono1, Shinji Watanabe1, Hiroki Yabe1, Masataka Kuwana2 and Chihiro Terai1, 1Department of Rheumatology, Saitama Medical Center, Jichi Medical University, Saitama, Japan, 2Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan

    Background/Purpose: Polymyositis (PM), dermatomyositis (DM), and clinically amyopathic DM (CADM) are systemic inflammatory diseases that affect skeletal muscle, skin, and other organs, such as lungs,…
  • Abstract Number: 2880 • 2017 ACR/ARHP Annual Meeting

    Clinical Evolution of Patients with Inflammatory Back Pain: A Population-Based Longitudinal Cohort Study

    Runsheng Wang1, Cynthia S. Crowson2, Kerry Wright3 and Michael Ward4, 1Rheumatology, Columbia University Medical Center, New York, NY, 2Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4NIH/NIAMS, Bethesda, MD

    Title: Clinical Evolution of Patients with Inflammatory Back Pain: a Population-Based Longitudinal Cohort Study Authors: Runsheng Wang1, Cynthia Crowson2, Kerry Wright2, Michael Ward31.       Columbia University…
  • Abstract Number: 2942 • 2017 ACR/ARHP Annual Meeting

    One Year Changes in Ultrasound Findings in the Feet Are Associated with Patient Reported Outcomes but Not Clinical Examination:  a Prospective Observational Study of Patients with Early Rheumatoid Arthritis

    Hanyan Zou1, Karen A. Beattie2, George Ioannidis3 and Maggie Larche2, 1McMaster University, Hamilton, ON, Canada, 2Medicine, McMaster University, Hamilton, ON, Canada, 3St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: Despite extensive involvement of the feet in early RA, few studies report clinical and imaging changes in the feet over time. In this observational…
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