ACR Meeting Abstracts

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Abstracts tagged "longitudinal studies"

  • Abstract Number: 668 • 2015 ACR/ARHP Annual Meeting

    Pasdas, Cpdai and MDA Evolution in the First 6 Months after Diagnosis of Early Psoriatic Arthritis Patients: Results of the Depar Study

    Jolanda Luime1, Ilja Tchetverikov2, Marijn Vis3, Cathelyne Appels4, Wiebo van der Graaff5, Josien Veris6, Andreas Gerards7, Hans van Groenendaal8, Mark Kok9, Lindy-Anne Korswagen10, Cor Stolk11 and Cicero, 1Department of Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands, 2Albert Schweitzer Ziekenhuis, Dordrecht, Netherlands, 3Rheumatology, ErasmusMC, Rotterdam, Netherlands, 4Rheumatology, Amphia Hospital, Breda, Netherlands, 5Rheumatology, Rivas hospital, Gorinchem, Netherlands, 6Rheumatology, Reumazorg Zuid West Nederland, Goes, Netherlands, 7Rheumatology, Vlietland Hospital, Schiedam, Netherlands, 8Rheumatology, Reumazorg Zuid West Nederland, Roosendaal, Netherlands, 9Maasstadweg 21, Maasstad Ziekenhuis, Rotterdam, Netherlands, 10Rheumatology, Sint Fransicus Gasthuis, Rotterdam, Netherlands, 11-, Patient Partner, Bunnink, Netherlands

    Background/Purpose: Several disease activity measures were developed for use in psoriatic arthritis (PsA) . Little data is available on their performance in usual care. This…
  • Abstract Number: 709 • 2015 ACR/ARHP Annual Meeting

    Progression of Patients with Non-Radiographic Axial Spondyloarthritis to Ankylosing Spondylitis: A Population-Based Cohort Study

    Runsheng Wang1, Sherine Gabriel2 and Michael M. Ward1, 1NIH/NIAMS, Bethesda, MD, 2Division of Rheumatology; Department of Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: The long-term outcome of patients with non-radiographic axial spondyloarthritis (nr-axSpA) is unclear, particularly whether few or most progress to ankylosing spondylitis (AS).  Our objective…
  • Abstract Number: 712 • 2015 ACR/ARHP Annual Meeting

    Factors Associated with Anti-TNF Treatment in a Longitudinally Followed Ankylosing Spondylitis (AS) Cohort

    Mary Gibson1, MinJae Lee2, Michael M. Ward3, Lianne S. Gensler4, Matthew A. Brown5, Shervin Assassi6, Colton Pence1, Laura A. Diekman7, Mohammad H. Rahbar8, Michael H. Weisman9 and John D. Reveille1, 1Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, 2Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, 3NIH/NIAMS, Bethesda, MD, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 5The University of Queensland Diamantina Institute, Brisbane, Australia, 6Rheumatology, University of Texas Medical School at Houston, Houston, TX, 7Rheumatology, University of Texas Medical School, Houston, TX, 8The University of Texas Health Science Center at Houston, Houston, TX, 9Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA

    Background/Purpose: TNF-α inhibitor therapy is recommended by ASAS/EULAR guidelines for ankylosing spondylitis (AS) patients with moderate-to-high disease activity despite inadequate response to NSAIDs  in addition…
  • Abstract Number: 716 • 2015 ACR/ARHP Annual Meeting

    Urinary Proteomics Identifies Three Novel Biomarkers for Lupus Nephritis Activity: Retinol Binding Protein, Alpha-1-Antichymotrysin and Haptoglobin

    Amita Aggarwal1, Sudhir sinha2, Ranjan Gupta3, Liza Rajasekhar4, Akhilesh Yadav3, Ramnath Misra1 and Virsingh Negi5, 1Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 2Department of Biochemistry, CSIR-central drug research institute, Lucknow, India, 3Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 4Department of Rheumatology, Nizam Institute of Medical Sciences, Hyderabad, India, 5Department of Clinical Immunology, JIPMER, Puducherry, India

    Background/Purpose: Urinary biomarkers have a potential for identification, follow-up and assessment of response to treatment in patients with lupus nephritis. Urinary proteomics can help in…
  • Abstract Number: 849 • 2015 ACR/ARHP Annual Meeting

    A Computational Tool for Individualized Prognosis of Percent of Predicted Forced Vital Capacity Trajectories in Systemic Sclerosis

    Peter Schulam1, Colin Ligon2, Robert Wise3, Laura K. Hummers4, Fredrick M. Wigley5 and Suchi Saria1,6, 1Department of Computer Science, Johns Hopkins University, Baltimore, MD, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Department of Pulmonology, Johns Hopkins University School of Medicine, Baltimore, MD, 4Johns Hopkins University School of Medicine, Baltimore, MD, 5Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD, 6Departments of Biostatistics, and Health Policy and Management, Bloomberg School of Public Health, Baltimore, MD

    Background/Purpose: Interstitial lung disease (ILD) is a common cause of mortality in systemic sclerosis (Ssc). Decreased forced vital capacity (FVC) in Ssc-ILD is associated with…
  • Abstract Number: 1645 • 2015 ACR/ARHP Annual Meeting

    Tofacitinib, an Oral Janus Kinase Inhibitor, in the Treatment of Rheumatoid Arthritis: Safety and Clinical and Radiographic Efficacy in Open-Label, Long-Term Extension Studies over 7 Years

    Jürgen Wollenhaupt1, Joel Silverfield2, Eun Bong Lee3, Ketti Terry4, Kenneth Kwok5, Irina Lazariciu6, Chudy Nduaka7, Carol A. Connell4, Ryan DeMasi5 and Lisy Wang4, 1Schoen-Klinik Hamburg-Eilbek Teaching Hospital of the University of Hamburg, Hamburg, Germany, 2Healthpoint Medical Group, Tampa, FL, 3Seoul National University, Seoul, South Korea, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, New York, NY, 6Quintiles, Saint-Laurent, QC, Canada, 7Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We report tofacitinib safety, tolerability, and clinical response over 84 months…
  • Abstract Number: 1708 • 2015 ACR/ARHP Annual Meeting

    Predictors of Depression Severity in Ankylosing Spondylitis

    Mark Hwang1, MinJae Lee2, Michael M. Ward3, Lianne S. Gensler4, Matthew A. Brown5, Shervin Assassi6, Laura A. Diekman7, Mohammad H. Rahbar8, Michael H. Weisman9 and John D. Reveille10, 1Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, 2Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, 3NIH/NIAMS, Bethesda, MD, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 5The University of Queensland Diamantina Institute, Brisbane, Australia, 6Rheumatology, University of Texas Medical School at Houston, Houston, TX, 7Rheumatology, University of Texas Medical School, Houston, TX, 8The University of Texas Health Science Center at Houston, Houston, TX, 9Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 10Rheumatology, University of Texas Health Science Center at Houston, Houston, TX

    Background/Purpose: Depression is a known comorbidity of ankylosing spondylitis (AS) with over one-third of AS patients affected and increased depression-rate ratio compared to the general…
  • Abstract Number: 2071 • 2015 ACR/ARHP Annual Meeting

    Urinary Osteoprotegerin As Biomarker of Lupus Nephritis Disease Activity: Cross Sectional and Longitudinal Study

    Ranjan Gupta1, Amita Aggarwal2, Sudhir sinha3, Liza Rajasekhar4, Akhilesh Yadav1, Priyanka Gaur1, Ramnath Misra2 and Virsingh Negi5, 1Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 2Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 3Department of Biochemistry, CSIR-central drug research institute, Lucknow, India, 4Department of Rheumatology, Nizam Institute of Medical Sciences, Hyderabad, India, 5Department of Clinical Immunology, JIPMER, Puducherry, India

    Background/Purpose: Urinary biomarkers may help in identification, treatment and assessment of response to therapy in patients with lupus nephritis (LN). Osteoprotegerin (OPG) is produced by…
  • Abstract Number: 2693 • 2015 ACR/ARHP Annual Meeting

    Comparing Eight Year Clinical and Radiographic Outcome in Two Cohorts of Patients with Rheumatoid Arthritis

    Maria LE Andersson1, Kristina Forslind2 and Ingiäld Hafström3, 1R&D Centre Spenshult,Halmstad, Halmstad, Sweden, 2Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, 3Rheumatology Dept, Karoliska Institute, Stockholm, Sweden

    Background/Purpose: To compare patient and disease characteristics over the first 8 years of disease in a large inception cohort of early RA patients included 1992…
  • Abstract Number: 3068 • 2015 ACR/ARHP Annual Meeting

    Damage Assessment in Takayasu’s Arteritis

    Antoine G. Sreih1, Tanaz A. Kermani2, David Cuthbertson3, Simon Carette4, Gary S. Hoffman5, Nader A. Khalidi6, Curry L. Koening7, Carol A. Langford5, Carol McAlear8, Paul A. Monach9, Larry W. Moreland10, Christian Pagnoux11, Philip Seo12, Kenneth J. Warrington13, Steven R. Ytterberg14 and Peter A. Merkel8, 1Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Rheumatology, University of California Los Angeles, Santa Monica, CA, 3Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 4Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 5Rheumatology, Cleveland Clinic, Cleveland, OH, 6McMaster University, Hamilton, ON, Canada, 7Division of rheumatology, George E. Wahlen Department of Veterans Affairs Medical Center Salt Lake City and University of Utah, University of Utah School of Medicine, Salt Lake City, UT, 8Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 9Section of Rheumatology, Vasculitis Center, Boston University School of Medicine, Boston, MA, 10Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 11Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 12Division of Rheumatology, Johns Hopkins, Baltimore, MD, 13Rheumatology, Mayo Clinic, Rochester, MN, 14Rheumatology Division, Mayo Clinic, Rochester, MN

       Background/Purpose: This study aimed to describe disease-related damage in Takayasu's arteritis (TAK) and evaluate damage assessment tools using data from a large longitudinal cohort. …
  • Abstract Number: 3146 • 2015 ACR/ARHP Annual Meeting

    Health Related Quality of Life in Adults with JIA – a 30 Year Longitudinal Study

    Anita Tollisen1,2,3, Anne Marit Selvaag1, Hanne A. Aulie1, Anners Lerdal4,5 and Berit Flato1,2, 1Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 2Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, 3Department of Medicine, Lovisenberg Diakonale Hospital, Oslo, Oslo, Norway, 4Faculty of Medicine, Institute of Health and Society, University of Oslo, Oslo, Norway, 5Lovisenberg Diakonale Hospital, Oslo, Oslo, Norway

    Background/Purpose: Improvement of health-related quality of life (HRQOL) is a central aim in treatment of patients with JIA. The primary aim of the study is…
  • Abstract Number: 907 • 2014 ACR/ARHP Annual Meeting

    Ultrasonographic Tenosynovitis Score Is Responsive to Biologic Treatment in Patients with Rheumatoid Arthritis

    Hilde B. Hammer1 and Tore K. Kvien2, 1Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Ultrasound (US) is sensitive for detecting tenosynovitis in patients with rheumatoid arthritis (RA), where the synovitis can be assessed by grey scale (GS) and…
  • Abstract Number: 849 • 2014 ACR/ARHP Annual Meeting

    Tofacitinib, an Oral Janus Kinase Inhibitor, in the Treatment of Rheumatoid Arthritis: Safety and Efficacy in Open-Label, Long-Term Extension up to 6 Years

    J. Wollenhaupt1, J. Silverfield2, E.B. Lee3, S.P. Wood4, K. Terry4, H. Nakamura5, K. Kwok6, A. Anisfeld6, C. Nduaka4, R. Riese4 and L. Wang4, 1Schoen-Klinik Hamburg-Eilbek Teaching Hospital of the University of Hamburg, Hamburg, Germany, 2Healthpoint Medical Group, Tampa, FL, 3Seoul National University, Seoul, South Korea, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, Tokyo, Japan, 6Pfizer Inc, New York, NY

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here we report tofacitinib safety, tolerability, and durability of response…
  • Abstract Number: 2654 • 2014 ACR/ARHP Annual Meeting

    Cognitive Function in Systemic Lupus Erythematosus Patients with Past History of Neuropsychiatric Manifestations : A Longitudinal Study

    Yang Gao1, Yi Lo1, Jacky Wan2, Esther YY Lau2 and Mo Yin Mok1, 1Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong, 2Department of Psychology, University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Cognitive impairment is commonly reported in patients with systemic lupus erythematosus (SLE) and its associations with neuropsychiatric involvement (NPSLE) and psychiatric factors have been…
  • Abstract Number: 2494 • 2014 ACR/ARHP Annual Meeting

    Persistence on Single Disease Modifying Anti-Rheumatic Drug Therapy in US Veterans with Rheumatoid Arthritis Is Extremely Rare

    Jonathan Kruger1, Michael Morgan1, Andreas Reimold2, Ted R. Mikuls3, Gail Kerr4 and Grant W. Cannon5, 1Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, 2Rheumatology, Dallas VA and Univ of TX Southwestern Med Ct, Dallas, TX, 3Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 4Rheumatology, Washington DC VA and Georgetown and Howard University, Washington, DC, 5Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT

    Background/Purpose:             Few rheumatoid arthritis (RA) patients are managed successfully with a single disease modifying anti-rheumatic drug (DMARD).  This investigation determined the prevalence and clinical…
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