ACR Meeting Abstracts

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Abstracts tagged "Lipids"

  • Abstract Number: 52 • 2013 ACR/ARHP Annual Meeting

    Altered Lipid Metabolism In Osteoarthritis With Subsequent Proinflammatory Properties Of Apolipoprotein A-I

    Dominique de Seny1, Gaël Cobraiville2, Edith Charlier3, Sophie Neuville2, Laurence Lutteri4, Denis Malaise5, Olivier Malaise3, Jean-Paul Chapelle4, Biserka Relic1 and Michel G. Malaise1, 1Department of Rheumatology, GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, 2GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, 3Department of Rheumatology, GIGA Research - University of Liège - CHU Liège, Liège, Belgium, 4Medical Chemistry - CHU Liège, Liège, Belgium, 5University of Liège, Liège, Belgium

    Background/Purpose: Osteoarthritis (OA) is associated with a local inflammatory process. It is now considered as a metabolic syndrome rather than due to aging or mechanical…
  • Abstract Number: 2827 • 2013 ACR/ARHP Annual Meeting

    Effect Of Biologic Agents On Lipids and Cardiovascular Risk In Rheumatoid Arthritis Patients

    Dimitrios A. Pappas1, Ani John2, Jeffrey R. Curtis3, George W. Reed4, Jeffrey D. Greenberg5, Ashwini Shewade2, Daniel H. Solomon6, Joel M. Kremer7 and Tanya Sommers4, 1Columbia University, New York, NY, 2Genentech Inc., South San Francisco, CA, 3Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4CORRONA, Inc., Southborough, MA, 5Departments of Medicine (Rheum Div) and Hospital for Joint Diseases, New York Hospital for Joint Diseases, New York, NY, 6Division of Pharmacoepidemiology, Harvard Medical School, Brigham and Women's Hospital, Division of Rheumatology, Division of Pharmacoepidemiology, Boston, MA, 7Medicine, Albany Medical College and the Center for Rheumatology, Albany, NY

    Background/Purpose: The risk for cardiovascular disease (CVD) is increased in patients (pts) with RA. The interplay between traditional CV risk factors and inflammatory burden may…
  • Abstract Number: 2332 • 2013 ACR/ARHP Annual Meeting

    Assessment of Lipid Changes and Infection Risk In Diabetic and Nondiabetic Patients With Rheumatoid Arthritis Treated With Tofacitinib

    W. F. C. Rigby1, L. Takiya2, S. P. Wood3, H. Fan2 and T. V. Jones2, 1Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, 2Pfizer Inc, Collegeville, PA, 3Pfizer Inc, Groton, CT

    Background/Purpose: Tofacitinib is a novel, oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Studies have shown an increased prevalence of diabetes mellitus…
  • Abstract Number: 2309 • 2013 ACR/ARHP Annual Meeting

    Quantifying The Gap Between General Population Guidelines and Expert Opinion For Cardiovascular Risk Management In Rheumatic Disease Patients

    Katherine P. Liao1, Jonathan Brown2, Jonathan S. Coblyn3, Paul Cohen2, Jorge Plutzky2 and Daniel H. Solomon4, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Cardiology, Brigham and Women's Hospital, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 4Division of Pharmacoepidemiology, Harvard Medical School, Brigham and Women's Hospital, Division of Rheumatology, Division of Pharmacoepidemiology, Boston, MA

    Background/Purpose: Cardiovascular (CV) risk is higher among rheumatic disease patients than the general population.  However, CV risk management guidelines calibrated for the rheumatic disease population…
  • Abstract Number: 1280 • 2013 ACR/ARHP Annual Meeting

    The Role of Sphingosine-1-Phosphate Receptor 3 Signaling in Murine Collagen-Induced Arthiritis

    Hidetake Nagahara1, Masataka Kohno1, Ken Murakami1, Aihiro Yamamoto1, Takahiro Seno1, Wataru Fujii1, Kazuki Fujioka1, Yuji Kukida1, Ryo Oda2, Hiroyoshi Fujiwara2 and Yutaka Kawahito1, 1Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, 2Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, kyoto, Japan

    Background/Purpose: Sphingolipids represent a major class of lipids that are ubiquitously expressed in eukaryotic cell membranes. Through the interaction with a family of five G-protein-coupled…
  • Abstract Number: 1166 • 2013 ACR/ARHP Annual Meeting

    Anti-Inflammatory Property Of HDL In NOD1 Ligand Induced Kawasaki Arteritis In Mice

    Hajime Kono1, Tamiko Yanagida2, Kurumi Asako1, Toshihiro Nanki1, Hirotoshi Kikuchi1, Akiko Okamoto1, Akiko Onda3 and Maki Takayama1, 1Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 2Depart ment of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 3Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan

    Background/Purpose: Atherosclerosis is a chronic metabolic disease of inflammatory processes. Immune cells including monocytes are recruited to the subintimal lesion of the vascular wall and…
  • Abstract Number: 450 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Monotherapy Compared With Adalimumab Monotherapy In Patients With Rheumatoid Arthritis: An Evaluation Of High-Density Lipoprotein Composition

    Cem Gabay1, Katie Tuckwell2, Jennifer Green2, Micki Klearman3 and Arthur Kavanaugh4, 1SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 2Roche, Welwyn Garden City, United Kingdom, 3Roche, South San Francisco, CA, 4University of California, San Diego, La Jolla, CA

    Background/Purpose: Rheumatoid arthritis (RA) patients (pts) are at increased risk for cardiovascular (CV) disease. Although analysis of lipids such as LDL-C and HDL-C is useful…
  • Abstract Number: 385 • 2013 ACR/ARHP Annual Meeting

    Systemic Inflammation In Patients With Inflammatory Joint Disease Does Not Influence Statin Dose Needed To Obtain Low Density Lipoprotein Cholesterol Goal In Cardiovascular Prevention

    Silvia Rollefstad1, Eirik Ikdahl2, Tore K. Kvien3,4, Terje R. Pedersen4,5, Ingar Holme6 and Anne G. Semb2, 1Rhuematology, Diakonhjemmet Hospital, Oslo, Norway, 2Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Faculty of Medicine, University of Oslo, Oslo, Norway, 5Centre of Preventive Medicine, Oslo University Hospital-Ullevaal, Oslo, Norway, 6Department of biostatistics, epidemiology and health economics, Oslo University Hospital-Ullevaal, Oslo, Norway

    Background/Purpose: There is a lipid paradox in rheumatoid arthritis (RA): despite low lipids influenced by systemic inflammation, there is an increased risk of cardiovascular (CV)…
  • Abstract Number: 1249 • 2012 ACR/ARHP Annual Meeting

    The Impact of Statin Use On Lipid Levels in Statin-Naive Patients with Rheumatoid Arthritis (RA) Vs. Non-RA Subjects: Results From a Population-Based Study

    Elena Myasoedova1, Cynthia S. Crowson2, Abigail B. Green2, Eric L. Matteson3 and Sherine E. Gabriel4, 1Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: Dyslipidemia in patients with rheumatoid arthritis (RA) is well recognized. The impact of lipid-lowering medications on lipid levels in patients with RA vs non-RA…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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