ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "leukocytes"

  • Abstract Number: 0036 • ACR Convergence 2021

    The NAD+ Metabolism Is Altered in Rheumatoid Arthritis and Its Modulation with NAD+ Boosters Exhibits Key Anti-Inflammatory and Anti-Oxidant Effects

    Carlos Pérez-Sánchez1, Luz Marina Sanchez-Mendoza2, Nuria Barbarroja3, M.Carmen Abalos-Aguilera4, Maria Luque-Tevar5, Alejandra Patiño-Trives5, Iván Arias de la Rosa3, Cristobal Román-Rodriguez6, Juan Antonio Moreno2, Maria Isabel Buron2, Jose Antonio Gonzalez-Reyes2, Marta Rojas-Gimenez4, Eduardo Collantes-Estevez6, alejandro Escudero6, Jose Manuel Villalba2 and Chary lopez-pedrera6, 1IMIBIC, Córdoba, Spain, 2Department of Cell Biology, Physiology and Immunology, University of Córdoba, Campus de Excelencia Internacional Agroalimentario, ceiA3, Cordoba, Spain, 3University of Cordoba/IMIBIC/Reina Sofia Hospital, Cordoba, Spain, 4Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Córdoba, Cordoba, Spain, 5Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, 6IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain

    Background/Purpose: NAD+ is a key cofactor and second messenger for multiple cellular processes that exhibits antioxidant, anti-apoptotic, and anti-inflammatory properties. Numerous publications and clinical trials…
  • Abstract Number: 2443 • 2018 ACR/ARHP Annual Meeting

    Trends in the Incidence of Lymphomas and Leukemias in Patients with Rheumatoid Arthritis in Spain: An Observational Cohort Study of Hospital Discharges from 1999 to 2015

    J.L Morell-Hita1, Ramon Mazzucchelli2, E Perez-Fernandez2, Javier Quirós2, Cristina Macia-Villa3, Natalia Crespí4, M Peña2, Carmen Barbadillo5, Maria Espinosa6, Hilda Godoy5, Manuel Fernández7, María Galindo8, Alberto Garcia-Vadillo9, O Guzon-Illescas2, Angela Herranz10, Cristina Martinez-Prada11, C Morado-Quiñoa11 and Virginia Villaverde García12, 1H.U.Ramón y Cajal, Madrid, Spain, 2H.U.Fundación Alcorcón, Madrid, Spain, 3Hospital Universitario Severo Ochoa, Madrid, Spain, 4C.S. La Rivota, Madrid, Spain, 5H.U. Puerta de Hierro, Madrid, Spain, 6Rheumatology, H.U. Puerta de Hierro, Madrid, Spain, 7Hospital Universitario de Guadalajara. Spain, Guadalajara, Spain, 8Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 9Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 10H.U. del Henares, Madrid, Spain, 11H.U. Clínico San Carlos, Madrid, Spain, 12Rheumatology, Hospital Universitario de Móstoles, Móstoles, Spain

    Background/Purpose: Oncohematological diseases have an increased incidence in Rheumatoid Arthritis (RA) patients. In the last years numerous studies have appeared exploring the relationship between these…
  • Abstract Number: 2656 • 2017 ACR/ARHP Annual Meeting

    Alterations of the Splicing Machinery Components in Leukocytes from Systemic Lupus Erythematosus Patients Influences Its Development and Atherothrombotic Profile and Drives the Therapeutic Response

    Carlos Perez-Sanchez1, Maria Ángeles Aguirre Zamorano1, Sergio Pedraza-Arévalo2, Mercedes del Río-Moreno2, Irene Cecchi3, Patricia Ruiz-Limon4, Nuria Barbarroja1, Yolanda Jiménez-Gómez1, Ivan Arias de la Rosa4, Maria Carmen Abalos-Aguilera4, Pedro Segui5, Eduardo Collantes-Estévez1, Justo P Castaño2, Raul M Luque6, Maria Jose Cuadrado7 and Chary Lopez-Pedrera1, 1Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 2Department of Cell Biology, Physiology and Immunology. University of Cordoba, Reina Sofia Hospital, IMIBIC, CIBERobn, and ceiA3, Córdoba, Spain, 3Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 4Rheumatology Service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 5Radiology, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 6Department of Cell Biology, Physiology and Immunology. University of Cordoba, Hospital Universitario Reina Sofia (HURS), Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), CIBERobn, and ceiA3, Córdoba, Spain, 7St Thomas Hospital, Lupus Research Unit, London, United Kingdom

    Background/Purpose: Recent studies emphasize the relevance of alternative splicing in the development of genetic and autoimmune diseases. The aim of this study was to identify…
  • Abstract Number: 32 • 2016 ACR/ARHP Annual Meeting

    Comparison of Effects of Leukocyte-RICH and Leukocyte-Poor Platelet-RICH Plasma on PAIN and Functionality in Patients with Lateral Epicondylitis

    Havva Talay Calis1, Melek Yerlikaya2, Serap Sütbeyaz3, Hatice Sayan2, Nurdan Özkan2, Ali Koç4 and Çiğdem Karakükçü5, 1Departmentbof Physical Medicine and Rehabilitation, Kayseri Education and Research Hospital, Kayseri, Turkey, 2Department of Physical Medicine and Rehabilitation, Kayseri Education and Research Hospital, Kayseri, Turkey, 3Department of Physical Medicine and Rehabilitation, Kayseri Edıcation and Research Hospital, Kayseri, Turkey, 4Department of Radiology, Kayseri Education and Tesearch Hospital, Kayseri, Turkey, 5Department of Biochemistry, Kayseri Education and Research Hospital, Kayseri, Turkey

    Comparison of effects of leukocyte-rich and leukocyte-poor platelet-rich plasma on pain and functionality in patients with lateral epicondylitis Melek Yerlikaya¹, Havva Talay  Çalýþ¹, Serap Tomruk…
  • Abstract Number: 2506 • 2014 ACR/ARHP Annual Meeting

    Decrease in the Number of Peripheral Leukocytes and Neutrophils and Increase of the Percentage of Eosinophils at 4 Week Predict the DAS28-ESR Remission at 24 Weeks after Administration of Tocilizumab

    Tamao Nakashita1, Shinji Motojima2 and Akira Jibatake3, 1[email protected], Kameda Medical Center, Kamogawa-city, Japan, 2[email protected], Kameda Medical Center, Kamogawa City, Japan, 3Depertment of Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan

    Background/Purpose : Tocilizumab (TCZ) is a monoclonal anti-IL-6 receptor antibody, and is very effective in controlling RA activity.  However we had noticed that the change…
  • Abstract Number: 1516 • 2014 ACR/ARHP Annual Meeting

    TNF-Alpha Inhibitors Normalizes Melanocortin Receptor Subtype 2, 3 and 4 Expression in CD8+, CD14+ and CD19+ Leukocyte Subsets in Rheumatoid Arthritis

    Marlene Andersen1, Michael Kruse Meyer2, Ivan Nagaev3, Olga Nagaeva3, Jarl E.S. Wikberg4, Lucia Mincheva-Nilsson3 and Grethe N. Andersen2, 1Department of Rheumatology, Aalborg University, Hjørring, Denmark, 2Clinic of Rheumatology, Hospital of Vendsyssel/Aalborg University, Hjørring, Denmark, 3Department of Clinical Immunology, University of Umeå, Umeå, Sweden, 4Department of Pharmaceutical Biosciences, Department of Pharmaceutical Pharmacology, Uppsala, Sweden

    Background/Purpose: We examined Adalimumab´s effects on melanocortin receptor subtype (MC)1-5 gene expression in important leukocyte subsets in rheumatoid arthritis (RA). The melanocortin system is a…
  • Abstract Number: 2544 • 2013 ACR/ARHP Annual Meeting

    Serum Mediated Phagocytosis Of Necrotic Material By Polymorphonuclear Leukocytes May Be Used As a Tool To Predict Clinical Manifestations In Systemic Lupus Erythematosus

    Michele Compagno1, Birgitta Gullstrand2, Andreas Jönsen3, Lennart Truedsson2, Gunnar Sturfelt4 and Anders A. Bengtsson3, 1Department of clinical sciences - Rheumatology, Lund University, Lund, Sweden, 2Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden, 3Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, 4Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden

    Background/Purpose: Polymorphonuclear (PMNs) leukocytes with engulfed necrotic cell material (NCM), as formerly used in the LE-cell test, are frequently seen in SLE and associated to…
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