Abstracts tagged "Knee"

Abstract Number: 1107 • 2012 ACR/ARHP Annual Meeting
Baseline Knee Flexion Pain, Age and Joint Line Tenderness Predict the Progression of Asymptomatic, Radiographic Knee Osteoarthritis to Symptomatic Knee Osteoarthritis Over 5 Years
Abhiram Gande¹ and James J. Irrgang², ¹Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, ²Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Knee Osteoarthritis (OA) is the most prevalent form of OA. Historically, not all people who have tell-tale signs of radiographic knee osteoarthritis progress to…
Abstract Number: 257 • 2012 ACR/ARHP Annual Meeting
Meta-Analysis of Four 12-Week Phase III Clinical Trials Investigating the Effect of TDT 064, a Transdermal Gel, in Osteoarthritis of the Knee
Matthias Rother¹, Johannes C. Vester², Wolfgang W. Bolten³ and Philip G. Conaghan⁴, ¹IMR Partner GmbH, Graefelfing, Germany, ²IDV Data Analysis and Study Planning, Krailling, Germany, ³Rheumatology, Klaus-Miehlke-Klink, Wiesbaden, Germany, ⁴University of Leeds, Leeds, United Kingdom
Background/Purpose: A transfersome is an ultradeformable lipid vesicle originally developed to deliver high concentrations of drug (eg NSAIDs) transdermally. Large interventional trials in osteoarthritis (OA)…
Abstract Number: 1585 • 2012 ACR/ARHP Annual Meeting
Physical Activity and Timing of Discharge From Physical Therapy Following Total Knee Replacement
Carol A. Oatis¹, Wenjun Li², Milagros Rosal³, David Ayers² and Patricia D. Franklin², ¹Physical Therapy, Arcadia University, Glenside, PA, ²Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ³Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA
Background/Purpose: In 2009 over 620,000 total knee replacement (TKR) surgeries were performed. That number is expected to increase to 3.5 million annually by 2030. Post-operative…
Abstract Number: 1083 • 2012 ACR/ARHP Annual Meeting
Physicians’ Recommendations for Total Knee Arthroplasty in Younger Persons with Moderate Osteoarthritis
Liana Fraenkel¹, Lawrence Weis² and Lisa Suter³, ¹Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ²Medicine, Yale University, New Haven, CT, ³Medicine, Rheumatol, TAC S541, Yale University, New Haven, CT
Background/Purpose: Rates of total knee arthroplasty (TKA) are increasing among all age groups. The most rapidly growing population of patients undergoing TKA are those under…
Abstract Number: 258 • 2012 ACR/ARHP Annual Meeting
Efficacy and Safety of the Chinese Herbal Compound Hou-Lou-Xiao-Ling Dan in Patients with Osteoarthritis of the Knee: Results of a Phase II International Study
Marc C. Hochberg¹, Lixing Lao², Patricia Langenberg³, Harry H. S. Fong⁴, David Y-W. Lee⁵ and Brian Berman², ¹Department of Medicine, University of Maryland, Baltimore, MD, ²Center for Integrative Medicine, University of Maryland, Baltimore, MD, ³University of Maryland, Baltimore, MD, ⁴University of Illinois at Chicago, Chicago, IL, ⁵Harvard Medical School, Boston, MA
Background/Purpose: Traditional Chinese Medicine (TCM), which includes the use of herbal medicines, is widely used to treat osteoarthritis (OA) of the knee in Asian societies;…
Abstract Number: 1553 • 2012 ACR/ARHP Annual Meeting
The Effect of Knee Replacement On Participation Outcomes: The Multicenter Osteoarthritis Study and Osteoarthritis Initiative
Jessica L. Maxwell¹, Jingbo Niu², Julie J. Keysor³, Tuhina Neogi⁴, Tianzhong Yang⁵, Michael C. Nevitt⁶, Jasvinder A. Singh⁷, Laura Frey-Law⁸ and David T. Felson⁹, ¹Physical Therapy & Athletic Training, Boston Univ Sargent College, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Physical Therapy, Boston University Sargent College, Boston, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ⁶Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁷Department of Medicine, University of Alabama, Tuscaloosa, AL, ⁸University of Iowa, Iowa City, IA, ⁹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Little research has explored participation outcomes, defined as involvement in life situations, among persons following knee replacement (KR). We recently reported (OARSI 2012) that…
Abstract Number: 1088 • 2012 ACR/ARHP Annual Meeting
Factors Influencing Long-Term Recovery of Total Knee Arthroplasty
C. Allyson Jones¹, Gian S. Jhangri² and Maria E. Suarez-Almazor³, ¹Departments of Physical Therapy and School of Public Health, University of Alberta, Edmonton, AB, Canada, ²School of Public Health, University of Alberta, Edmonton, AB, Canada, ³The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX
Background/Purpose: Although a number of studies have examined short term outcomes after total knee arthroplasty (TKA), few have prospectively examined the long term trajectory of…
Abstract Number: 265 • 2012 ACR/ARHP Annual Meeting
Reducing Loads in the Contralateral Side in Medial Knee Osteoarthritis; A 3-Year Follow-up Study
Roy H. Lidtke and Joel A. Block, Section of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: No strategies have been shown to prevent Medial knee osteoarthritis (MKOA). For those with symptomatic unilateral MKOA, the contralateral knee may be at risk…
Abstract Number: 2533 • 2012 ACR/ARHP Annual Meeting
Weight Loss Is Associated with Structure Modification in Subjects with Radiographic Osteoarthritis of the Knee: Data From the Osteoarthritis Initiative
Marc C. Hochberg¹, Danuta I. Bujak², Jeffrey W. Duryea³, Knachelle Favors⁴ and John D. Sorkin⁴, ¹Department of Medicine, University of Maryland, Baltimore, MD, ²School of Medicine, University of Maryland, Baltimore, MD, ³Dept of Radiology, Brigham & Women, Boston, MA, ⁴VA Maryland Health Care System, Baltimore, MD
Background/Purpose: Obesity is a risk factor for the development and progression of knee osteoarthritis (OA) and weight loss is recommended as part of the management…
Abstract Number: 1120 • 2012 ACR/ARHP Annual Meeting
Cartilage Volume Loss Occurs in Most Older Adults and the Rate of Loss Increases with Age
Andreea M. Harsanyi¹, Dawn Dore², Changhai Ding³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicutinni⁵ and Graeme Jones³, ¹Menzies Research Institute Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ³Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia
Background/Purpose: Radiographic data suggests knee osteoarthritis is a relatively static disease even over the long term. It is uncertain how much this is influenced by…
Abstract Number: 1090 • 2012 ACR/ARHP Annual Meeting
A Comparison of Patient-Reported and Measured Range of Motion in a Cohort of Total Knee Replacement Patients
Jamie E. Collins¹, Benjamin N. Rome¹, Vladislav Lerner¹, Jeffrey N. Katz² and Elena Losina¹, ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Range of motion (ROM) is an important component of the assessment of total knee replacement (TKR) outcome. Traditionally, ROM is measured by a clinician…
Abstract Number: 266 • 2012 ACR/ARHP Annual Meeting
Knee Joint Stabilization Therapy in Patients with Osteoarthritis of the Knee: A Randomized, Controlled Trial
Jesper Knoop¹, Joost Dekker², Marike van der Leeden³, Martin van der Esch¹, Carina A. Thorstensson⁴, Martijn Gerritsen⁵, Ramon E. Voorneman⁵, Wilfred FH Peter¹, Mariette de Rooij¹, Suzanne Romviel¹, Willem F. Lems⁶, Leo D. Roorda⁷ and Martijn P.M. Steultjens⁸, ¹Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²VU University Medical Centre, Department of Rehabilitation Medicine, EMGO Institute and Department of Psychiatry, Amsterdam, Netherlands, ³Amsterdam Rehabilitation Research Center, Reade, Amsterdam, Netherlands, ⁴Department of Clinical Neurosciences and Rehabilitation, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, Sweden, ⁵Jan van Breemen Research Institute, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ⁶Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ⁷Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁸Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland
Background/Purpose: Patients with knee osteoarthritis (OA) and instability of the knee joint may not benefit optimally from regular strengthening training. Therefore, we evaluated the effectiveness of a newly…
Abstract Number: 2537 • 2012 ACR/ARHP Annual Meeting
Cross-Sectional and Longitudinal Associations Between Circulating Leptin and Knee Cartilage Thickness in Older Adults
Oliver Stannus¹, Yuelong Cao², Benny Samuel Eathakkattu Antony¹, Graeme Jones³ and Changhai Ding⁴, ¹Musculoskeletal, Menzies Research Institute Tasmania, Hobart, Australia, ²Musculoskeletal, Orthopaedics, Menzies Research Institute Tasmania, Research Institute of Orthopaedics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,, Hobart, Australia, ³Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ⁴Musculoskeletal and Epidemilogy, Menzies research institute & Monash University, Hobart, Australia
Background/Purpose: To investigate cross-sectional and longitudinal associations between serum leptin levels and knee cartilage thickness in older adults. Methods: A prospective cohort of 163 randomly…
Abstract Number: 1123 • 2012 ACR/ARHP Annual Meeting
Comparison of Anatomic Knee Alignment On Physical Examination and Radiographs
Iman Hemmati¹, Eric C. Sayre², Ali Guermazi³, Savvakis Nicolaou⁴, Anona Thorne⁵, Joel Singer⁶ and Jolanda Cibere⁷, ¹Deparment of Medicine and Rheumatology, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Centre of Canada, Vancouver, BC, Canada, ³Radiology, Boston University, Boston, MA, ⁴Department of Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵School of Population and Public Health, University of British Columbia, Canadian Institutes of Health Research HIV Trials Network, Vancouver, BC, Canada, ⁶School of Population and Public Health, University of British Columbia, University of British Columbia, Vancouver, BC, Canada, ⁷Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada
Background/Purpose: Severity of knee malalignment is a risk factor for osteoarthritis (OA) progression. Currently the hip-knee-angle (mechanical axis), assessed on a full-limb radiograph, is the…
Abstract Number: 1093 • 2012 ACR/ARHP Annual Meeting
Obesity Is Not a Risk Factor for Poor Pain and Function Two Years After Total Knee Replacement
Lisa A. Mandl¹, Mark P. Figgie², Alejandro Gonzalez Della Valle³, Michael Alexiades³ and Susan M. Goodman¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Orthopedics, Hospital for Special Surgery, New York, NY, ³Orthopaedics, Hospital for Special Surgery, New York, NY
Background/Purpose: Almost 90% of referring physicians think obesity increases the likelihood of poor outcomes after total knee replacement (TKR). However, current data are conflicting. The…

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