Abstracts tagged "Knee"

Abstract Number: 1005 • 2015 ACR/ARHP Annual Meeting
Association of Baseline Knee Sagittal Dynamic Joint Stiffness during Gait and 2-Year Cartilage Damage Progression in Knee Osteoarthritis (OA)
Alison H. Chang¹, Joan S. Chmiel², Orit Almagor³, Kirsten C. Moisio³, Laura Belisle³, Yunhui Zhang³, Karen W. Hayes⁴ and Leena Sharma⁵, ¹PT & Human Movement Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Department of Physical Therapy and Human Movement Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: While patellofemoral (PF) OA has been found to have substantial impact on pain and function, most studies continue to focus on tibiofemoral (TF)…
Abstract Number: 2389 • 2015 ACR/ARHP Annual Meeting
Relation of Pronated Foot Posture to Risk of Worsening Knee Pain during Gait and Compartment-Specific Knee Cartilage Damage
K. Douglas Gross^1,2, Howard J. Hillstrom³, Emily K. Quinn⁴, Michael C. Nevitt⁵, Cora E. Lewis⁶, James Torner⁷ and David T. Felson², ¹Physical Therapy, MGH Institute of Health Professions, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Rehabilitation, Hospital for Special Surgery, New York, NY, ⁴Clinical Epidemiology Unit, Boston University, Boston, MA, ⁵Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁶Preventive Medicine, University of Alabama, Birmingham, AL, ⁷Epidemiology, University of Iowa, Iowa City, IA
Background/Purpose: Pronated foot posture is prevalent in older adults with knee cartilage damage and younger adults with knee pain. Yet, there is disagreement about the…
Abstract Number: 1006 • 2015 ACR/ARHP Annual Meeting
Incident Frequent Knee Pain Is Associated with Changes in Semi-Quantitative Imaging Biomarkers of Inflammation
C.Kent Kwoh¹, Michael J. Hannon², Tomoko Fujii³, Frank W Roemer⁴, Ali Guermazi⁵, David Hunter⁶, Felix Eckstein⁷ and Robert M. Boudreau⁸, ¹Department of Medicine, The University of Arizona Arthritis Center and Division of Rheumatology, Tucson, AZ, ²Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, ⁸Epidemiology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The cause of knee pain in osteoarthritis (OA) is multi-factorial, and there is increasing evidence of the role of inflammation in OA. The goal…
Abstract Number: 2395 • 2015 ACR/ARHP Annual Meeting
Predictors of and Longitudinal Factors Associated with Change in Pain, Stiffness and Physical Function over 8 Years in a Midlife Cohort with a Low Prevalence of Knee Osteoarthritis
Hussain Ijaz Khan¹, Andrew McBride², Louisa Chou³, Dawn Aitken⁴, Leigh Blizzard⁵, Changhai Ding⁶, Jean-Pierre Pelletier⁷, Johanne Martel-Pelletier⁸, Flavia Cicuttini⁹ and Graeme Jones⁶, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ⁴Muscyloskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ⁵Biostatistics, Menzies Institute of Medical Research, Hobart, Australia, ⁶Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁷Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ⁸Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁹Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Knee Osteoarthritis (OA) is the most common musculoskeletal condition affecting quality of life and was one of the leading causes of the years lived…
Abstract Number: 1011 • 2015 ACR/ARHP Annual Meeting
Impact of a Musculoskeletal “Mini-Residency” Continuing Professional Education Program on Knee MRI Orders By Primary Care Providers
Matthew Call^1,2, Andrea M. Barker³, Grant W. Cannon⁴, Phillip Lawrence⁵ and Michael J. Battistone⁶, ¹Rheumatology, University of Utah, Salt Lake City, UT, ²Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ³General Internal Medicine, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁴Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁵Pharmacology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT
Background/Purpose: The US Department of Veterans Affairs (VA) has developed a national continuing professional development program to train primary care providers (PCPs) in the evaluation…
Abstract Number: 2396 • 2015 ACR/ARHP Annual Meeting
The Absence of Symptom in Subjects with Advanced Knee OA
Son Kyeong Min¹, Dong-Hyun Kim², Myung Hee Cho³, Dae Gyu Jang³ and Hyun Ah Kim⁴, ¹Chunchun Sacred Heart Hosp, 153, Chunchun, South Korea, ²Deparment of Social and Preventive Medicine, Hallym University College of Medicine, Chunchon, South Korea, ³Department of Statistics, Seoul National University, seoul, South Korea, ⁴Division of Rheumatology, Hanlim University Hospital, Anyang, South Korea
Background/Purpose: Although osteoarthritis(OA) is predominantly considered as a disease of cartilage, articular cartilage is an aneural tissue, and there is a consensus that the association…
Abstract Number: 1281 • 2015 ACR/ARHP Annual Meeting
Reduction in Rural-Urban Disparity in Discharge Disposition to Home after Total Knee Arthroplasty in the U.S
Jasvinder A. Singh and Rekha Ramachandaran, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Rural-urban disparities in outcomes after total joint arthroplasty are of great interest, given the differences in health care access and social support between those…
Abstract Number: 2404 • 2015 ACR/ARHP Annual Meeting
Implications of a Positive Patellar Bulge Sign of Knee Joint Effusion in Patients with Osteoarthritis: Association with MRI Signs of Inflammation and with Increased Rate of 5-Year Total Knee Arthroplasty. Data from the Osteoarthritis Initiative
Benjamin Smith¹, David McDougall², Robert G Lambert³, Walter Maksymowych⁴ and Jacob Jaremko³, ¹Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ²Radiology, University of Alberta, Edmonton, AB, Canada, ³Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Most of our understanding of the clinical significance of a knee joint effusion is derived from trauma in young patients, with surprisingly little assessment…
Abstract Number: 150 • 2015 ACR/ARHP Annual Meeting
A Preliminary Consensus on Core Outcome Domains for Total Joint Replacement Clinical Trials: An Omeract-Based Study
Jasvinder A. Singh¹ and Michael Dohm², ¹University of Alabama at Birmingham, Birmingham, AL, ²Orthopaedic Surgery, Univ of Arizona, Tucson, AZ, Tucson, AZ
Background/Purpose: Outcomes Measures in Rheumatology Trials (OMERACT) has developed a framework based on the WHO’s International Classification of Functioning, Disability, and Health (ICF) conceptual model. …
Abstract Number: 1299 • 2015 ACR/ARHP Annual Meeting
Can Bone Marrow Lesions be Scored More Reliably and Responsively in Knee Osteoarthritis Using a Web-Based Overlay System (KIMRISS) Than By Standard MRI Osteoarthritis Knee Scoring (MOAKS)? Data from the Osteoarthritis Initiative and a Prospective Trial of Adaluminab Therapy
Jacob Jaremko¹, Mark Buller², Dean Jeffery², David McDougall³, Benjamin Smith², Robert G Lambert¹ and Walter Maksymowych⁴, ¹Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ²Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) relate to pain and prognosis in knee osteoarthritis. The Knee Inflammation MRI Scoring System (KIMRISS) offers simple template-assisted binary BML…
Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting
Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties
Kelly Forrester¹, Farah Taufiq¹ and Jonathan Samuels^2,3, ¹NYU Langone Medical Center, New York, NY, ²Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ³Rheumatology, NYU Langone Medical Center, New York, NY
Background/Purpose: Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…
Abstract Number: 180 • 2015 ACR/ARHP Annual Meeting
Ultrasound Quantification of Fluid Shifts in the Knees of Arthritis Patients before and after Inflation of a Pneumatic Compressive Device
Richard Meehan¹, christopher wilson², eric Hoffman³, Elizabeth Regan⁴ and Lynne Altimier⁵, ¹Medicine, National Jewish Health, Denver, CO, ²biomedical enginering, Unviersity of Colorado- Denver, Denver, CO, ³medicine, national Jewsih Health, westminster, CO, ⁴medicine, national Jewish Health.org, denver, CO, ⁵radiology, National Jewish Health, denver, CO
Background/Purpose: Published studies indicate clinicians may miss the intrasynovial knee space during therapeutic injections in excess of 30% of attempts using landmark guided techniques due…
Abstract Number: 1300 • 2015 ACR/ARHP Annual Meeting
Comparison Between Semiquantitative and Quantitative Methods for the Assessment of Knee Synovitis Using Non-Enhanced and Gadolinium-Enhanced MRI
Michel D. Crema¹, Frank Roemer², Ling Li³, Laura B. Rosen⁴, Amanda Dudley⁵, Robert Alexander⁶ and Ali Guermazi⁷, ¹Department of Radiology, Boston University School of Medicine, Boston, MA, ²Radiology, Boston University School of Medicine, Boston, MA, ³Dana-Farber Cancer Institute, Boston, MA, ⁴AstraZeneca Neuroscience Innovative Medicines, Cambridge, MA, ⁵AstraZeneca Neuroscience Innovative Medicines, Cambridge, United Kingdom, ⁶Pfizer Neuroscience, Cambridge, MA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: There is evidence that the presence of synovitis in knee osteoarthritis (OA) is clinically relevant since it is associated with pain and structural…
Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting
Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best
Elien A.M. Mahler¹, Nienke Cuperus², Johannes W J Bijlsma³, Thea Vliet Vlieland⁴, Frank H.J. van den Hoogen⁵, Alfons den Broeder⁵ and Cornelia H.M. van den Ende¹, ¹Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…
Abstract Number: 314 • 2015 ACR/ARHP Annual Meeting
A Double-Blind, Randomized, Controlled, Four Parallel Arm, Dose-Finding Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Single Intra-Articular (IA) Injections of Fasitibant in Patients with Symptomatic OA of the Knee
Claudia Gabriele Werner¹, Karel Pavelka², Andrea Nizzardo³, Cristina Rossi³, Simona Scartoni³, Maria Paola Contini³, Serena di Molfetta³, Monica Bertolotti³, Angela Capriati³ and Carlo Alberto Maggi⁴, ¹Clinical Research, A. Menarini Research & Business Service GmbH, Berlin, Germany, ²Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ³Clinical Research Department, Menarini Ricerche S.p.A., Florence, Italy, ⁴Menarini Ricerche S.p.A., Florence, Italy
Background/Purpose: Fasitibant (FAS) is a competitive, potent and selective antagonist of the bradykinin B2 receptor administered IA for SOAK. In response to positive outcomes in…

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