Abstracts tagged "Knee"

Abstract Number: 1300 • 2015 ACR/ARHP Annual Meeting
Comparison Between Semiquantitative and Quantitative Methods for the Assessment of Knee Synovitis Using Non-Enhanced and Gadolinium-Enhanced MRI
Michel D. Crema¹, Frank Roemer², Ling Li³, Laura B. Rosen⁴, Amanda Dudley⁵, Robert Alexander⁶ and Ali Guermazi⁷, ¹Department of Radiology, Boston University School of Medicine, Boston, MA, ²Radiology, Boston University School of Medicine, Boston, MA, ³Dana-Farber Cancer Institute, Boston, MA, ⁴AstraZeneca Neuroscience Innovative Medicines, Cambridge, MA, ⁵AstraZeneca Neuroscience Innovative Medicines, Cambridge, United Kingdom, ⁶Pfizer Neuroscience, Cambridge, MA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: There is evidence that the presence of synovitis in knee osteoarthritis (OA) is clinically relevant since it is associated with pain and structural…
Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting
Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best
Elien A.M. Mahler¹, Nienke Cuperus², Johannes W J Bijlsma³, Thea Vliet Vlieland⁴, Frank H.J. van den Hoogen⁵, Alfons den Broeder⁵ and Cornelia H.M. van den Ende¹, ¹Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…
Abstract Number: 314 • 2015 ACR/ARHP Annual Meeting
A Double-Blind, Randomized, Controlled, Four Parallel Arm, Dose-Finding Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Single Intra-Articular (IA) Injections of Fasitibant in Patients with Symptomatic OA of the Knee
Claudia Gabriele Werner¹, Karel Pavelka², Andrea Nizzardo³, Cristina Rossi³, Simona Scartoni³, Maria Paola Contini³, Serena di Molfetta³, Monica Bertolotti³, Angela Capriati³ and Carlo Alberto Maggi⁴, ¹Clinical Research, A. Menarini Research & Business Service GmbH, Berlin, Germany, ²Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ³Clinical Research Department, Menarini Ricerche S.p.A., Florence, Italy, ⁴Menarini Ricerche S.p.A., Florence, Italy
Background/Purpose: Fasitibant (FAS) is a competitive, potent and selective antagonist of the bradykinin B2 receptor administered IA for SOAK. In response to positive outcomes in…
Abstract Number: 1413 • 2015 ACR/ARHP Annual Meeting
Medial Meniscus Extrusion and Spontaneous Osteonecrosis of the Knee
Tadashi Yasuda, Soichiro Masuda, Yuka Miyazaki, Makoto Hayashi, Yusuke Yamawaki, Mutsumi Watanabe, Hisataka Takeuchi, Satoshi Ota, Satoshi Fujita, Eijiro Onishi, Koichi Iwaki and Hiroshi Yamamoto, Department of Orthopaedic Surgery, Kobe City Medical Center General Hospital, Kobe, Japan
Background/Purpose: Although the pathogenesis of spontaneous osteonecrosis of the knee (SONK) remains unclear, two main etiologies have been suggested in the pathogenesis of SONK: vascular…
Abstract Number: 2414 • 2015 ACR/ARHP Annual Meeting
High-Intensity Versus Low-Intensity Physical Activity or Exercises in Patients with Hip or Knee Osteoarthritis: A Meta-Analysis
Jean-Philippe Regnaux^1,2,3, Marie-Martine Lefèvre-Colau⁴, Ludovic Trinquart³, Christelle Nguyen⁵, Isabelle Boutron^1,3,6,7, Lucie Brosseau⁸ and Philippe Ravaud^3,6,7,9, ¹METHODS team, INSERM UMR-S 1153, Paris, France, ²EHESP Rennes, Sorbonne Paris Cité, Paris, France, ³French Cochrane Center, Paris, France, ⁴Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de rééducation et réadaptation de l’appareil locomoteur et des pathologies du rachis, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁵Univ. Paris Descartes, PRES Sorbonne Paris, Cité Laboratoire de Pharmacologie, Toxicologie et Signalisation Cellulaire, INSERM UMR-S 1124, UFR Biomédicale des Saints Pères, Paris, France, Paris, France, ⁶Paris Descartes University, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, ⁷Centre d’Épidémiologie Clinique, AP-HP (Assistance Publique des Hôpitaux de Paris), Hôpital Hôtel Dieu, Paris, France, ⁸Rehabilitation Sciences, University of Ottawa, Ottawa, ON, Canada, ⁹METHODS team, INSERM U1153, Paris, France
Background/Purpose: Exercise or physical activity are complex interventions whose effectiveness depends on more than one component. We aimed to determine the benefits and harms of…
Abstract Number: 322 • 2015 ACR/ARHP Annual Meeting
Reduction of Treatment Needed for Knee Osteoarthritis after Bariatric Surgery
Evan Wilder¹, Janice Lin¹, Fernando Bomfim¹, Thayer Mukherjee¹, Lucy O'Shaughnessy¹, Lauren Browne¹, Myriam Weill¹, Kevin Gernavage¹, Farah Taufiq¹, Renata La Rocca Vieira², Christine Ren-Fielding³, Manish Parikh⁴, Steven B. Abramson⁵ and Jonathan Samuels⁶, ¹NYU Langone Medical Center, New York, NY, ²Department of Radiology, NYU Langone Medical Center, New York, NY, ³Department of Surgery, New York University School of Medicine, New York, NY, ⁴Department of Surgery, NYU Langone Medical Center, New York, NY, ⁵Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY, ⁶Rheumatology, NYU - Hospital for Joint Diseases, New York, NY
Background/Purpose: Medical treatment for knee osteoarthritis (KOA) can be limited and risk morbidity. Weight loss reduces the arthritis burden and may preclude aggressive treatment. Bariatric…
Abstract Number: 1419 • 2015 ACR/ARHP Annual Meeting
Increasing Comorbidity Is Associated with Worsening Physical Function during Intermediate-Term Follow-up of Primary Total Knee Arthroplasty
Maren Hilton¹, Terence Gioe² and Jasvinder A. Singh³, ¹Arthritis and Rheumatology Consultants, Edina, MN, ²Department of Orthopaedic Surgery, Minneapolis VA Medical Center, Minneapolis, MN, ³University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Total knee arthroplasty (TKA) is associated with significant gains in function and pain improvement. However, decline in function has been noted in patients who…
Abstract Number: 3251 • 2015 ACR/ARHP Annual Meeting
The Relation of Massive Weight Loss to Changes in Knee Pain and Sensitization
Joshua Stefanik^1,2, David T. Felson³, Jingbo Niu³, Anyu Hu⁴, Caroline Apovian⁵, Michael P. Lavalley⁶ and Tuhina Neogi⁷, ¹Northeastern University, Boston, MA, ²Clinical Epidemiology, Boston University, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Clinical Epidemiology Research Unit, Boston University School of Medicine, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Biostatistics, Boston University School of Public Health, Boston, MA, ⁷Clinical Epidemiology, Boston University School of Medicine, Boston, MA
Background/Purpose: Individuals with chronic knee pain often develop central and/or peripheral sensitization (altered pain processing of the nervous system). Whether improvements in knee pain are…
Abstract Number: 324 • 2015 ACR/ARHP Annual Meeting
Activity Limitations in Persons with Low, Medium, and High Levels of Pain Prior to Total Knee Replacement: Implications for Appropriateness and Efficacy
Ilana M. Usiskin¹, Heidi Y. Yang¹, Bhushan R. Deshpande¹, Jamie E. Collins², Griffin L. Michl¹, Savannah R. Smith³, Kristina M. Klara¹, Jeffrey N. Katz² and Elena Losina⁴, ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ⁴Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopaedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Historically, persons with knee OA considered for total knee replacement (TKR) have had severe pain, as reflected in high WOMAC scores, in addition to…
Abstract Number: 1497 • 2015 ACR/ARHP Annual Meeting
Panlar Consensus on Hand, Hip and Knee OA
Oscar Luis Rillo¹, Humberto Riera², Rolando Espinosa-Morales³, Carlota Acosta⁴, Veronica Liendo⁵, Joyce Bolaños⁶, Ligia Monterola⁷, Edgar Nieto⁸, Luisa M. Franco⁹, Rodolfo Arape¹⁰, Ana Antunez¹¹, Silvia Beatriz Papasidero¹², Mariflor Vera¹³, Jorge Esquivel¹⁴, Renee Souto¹⁵, Jose F. Molina¹⁶, César Rossi¹⁷, Francisco Ballesteros¹⁸, José Salas¹⁹, Francisco Radrigan²⁰, Marlene Guibert-Toledano²¹, Gil Reyes Llerena²², Lorena Urioste²³, Walter Camacho²⁴, Abraham García²⁵, Isa Iraheta²⁶, Carmen E Gutierrez²⁷, Raúl Aragón²⁸, Margarita Duarte²⁹, Oswaldo Castañeda³⁰, Juan Angulo Solimano³¹, Ibsen Coimbra³², Roberto Munoz Louis³³, Carlos Vallejo³⁴, Ricardo Saenz³⁵, Francisco Giron³⁶, Anibal De León³⁷, Ramon Perez Acuna³⁸, Anthony M. Reginato³⁹ and Maritza Quintero², ¹Hospital General de Agudos “Dr. Ignacio Pirovano”, Buenos Aires, Argentina, ²Unidad de Reumatología, Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes, Mérida, Venezuela, ³Mexican Board of Rheumatology, Mexico City, Mexico, ⁴Ciudad Bolivar, Hospital Universitario "Ruiz y Páez, Bolivar, Venezuela, ⁵Clínica Roosevelt, Caracas, Venezuela, ⁶Hospital Perez Carreño, Caracas, Venezuela, ⁷Clínica Colinas, Anzoátegui, Venezuela, ⁸Traumatology, Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes, Mérida, Venezuela, ⁹Instituto Docente de Urología, Carabobo, Venezuela, ¹⁰Centro Clínico La Isabelica, Carabobo, Venezuela, ¹¹Hospital Central Dr. URQUINAONA, Maracaibo, Venezuela, ¹²Rheumatology Department, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ¹³Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes, Mérida, Venezuela, ¹⁴Universidad Autónoma de Nuevo León, Distrito Federal, Mexico, ¹⁵Catedra de Reumatología de la Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay, ¹⁶Centro Integral de Reumatologia Reumalab, Medellin, Colombia, ¹⁷Cátedra de Reumatología de la Facultad de Medicina, Universidad de la República, Montevideo, Uruguay, ¹⁸Departamento de Reumatología, Universidad de Chile, Santiago, Chile, ¹⁹Reumacaribe, Barranquilla, Colombia, ²⁰Departamento de Reumatología, Universidad Católica de Chile, Santiago, Chile, ²¹Rheumatology, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, ²²Servicio Nacional de Reumatología, Centro de Investigaciones Médico Quirúrgicas (CIMEQ), La Habana, Cuba, ²³Hospital Alfonzo Gumucio-Techo Académico Universidad Católica, San Pablo, Bolivia, ²⁴Servicio de Medicina Interna, Hospital Obrero N° 3 de la Caja Nacional de Salud, Santa Cruz, Bolivia, ²⁵Postgrado de Reumatología, Universidad Francisco Marroquí, Guatemala, Guatemala, ²⁶Rheumatology, Guatemalan Association against Rheumatic Diseases (AGAR), Guatemala City, Guatemala, ²⁷Instituto Salvadoreño del Seguro Social, San Miguel, El Salvador, ²⁸FACULTAD DE MEDICINA, UNIVERSIDAD DE EL SALVADOR., San Salvador, El Salvador, ²⁹Servicio de Reumatología, Hospital de Clínicas de Asunción, Universidad Nacional de Asunción, Asunción, Paraguay, ³⁰Clínica Angloamericana, Lima, Peru, ³¹Rheumatology, Universidad Nacional Mayor San Marcos, Lima, Peru, ³²Departamento de Clínica Médica, Faculdade de Ciências Médicas da UNICAMP, Campinas, Brazil, ³³Reumatologia, Clinica Abreu - Hospital Docente Padre Billini, Santo Domingo, Dominican Republic, ³⁴FACULTAD DE MEDICINA. PONTIFICIA UNIVERSIDAD CATOLICA DEL ECUADOR., Quito, Ecuador, ³⁵Hospital Dr. Rafael A. Calderón Guardia, San José, Costa Rica, ³⁶IHSS Tegucigalpa, Tegucigalpa, Honduras, ³⁷Hospital Santo Tomás, Panama, Panama, ³⁸Zona franca ultrpark 6A, Zona franca ultrpark 6A, La Aurora de Heredia, Costa Rica, ³⁹Rheumatology, Rhode Island Hospital, The Warren Alpert School of Medicine at Brown University, Providence, RI
Background/Purpose: The purpose of this Consensus is to update the PANLAR recommendations for hand, hip and knee osteoarthritis (OA) based on a combination of the…
Abstract Number: 3252 • 2015 ACR/ARHP Annual Meeting
Impact of Knee Pain Frequency on Physical Function in the Osteoarthritis Initiative
Jin Zhou¹, Erin Ashbeck², Lynn Hamilton² and C. Kent Kwoh³, ¹Epidemiology & Biostatistics, University of Arizona, Tucson, AZ, ²Arthritis Center, University of Arizona, Tucson, AZ, ³Rheumatology, University of Arizona, Tucson, AZ
Background/Purpose: Knee pain is a prominent symptom among patients with knee osteoarthritis (OA), but the impact of knee pain frequency on physical function has been…
Abstract Number: 326 • 2015 ACR/ARHP Annual Meeting
Older Adults without Extreme Obesity Are at Highest Risk for Accelerated Knee Osteoarthritis
Jeffrey Driban¹, Grace H. Lo², Charles B. Eaton³, Lori Lyn Price⁴, Bing Lu⁵, Mary Barbe⁶ and Timothy E. McAlindon⁷, ¹Tufts Medical Center, Boston, MA, ²VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ³Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁴Clinical Care Research, Tufts Medical Center, Boston, MA, ⁵Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁶Temple University School of Medicine, Philadelphia, PA, ⁷Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Accelerated knee osteoarthritis (AKOA) may be a unique subset of knee osteoarthritis (KOA). AKOA is more common among those who are older, overweight, or…
Abstract Number: 2092 • 2015 ACR/ARHP Annual Meeting
Knee Pain Burden Is Associated with Decreased Moderate to Vigorous Physical Activity: Data from the Osteoarthritis Initiative
Javad Razjouyan¹, Bijan Najafi², Erin Ashbeck³, Dorothy D. Dunlop⁴, Julia (Jungwha) Lee⁵, Lynn Hamilton³ and C. Kent Kwoh⁶, ¹Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, University of Arizona, Tucson, AZ, ²Department of Surgery and Department of Biomedical Engineering, University of Arizona, Tucson, AZ, ³Arthritis Center, University of Arizona, Tucson, AZ, ⁴Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology, University of Arizona, Tucson, AZ
Knee Pain Burden is Associated with Decreased Motor Performance: Data from the Osteoarthritis InitiativeBackground/Purpose: The influence of knee pain perception on daily life motor performance…
Abstract Number: 3269 • 2015 ACR/ARHP Annual Meeting
Trends in Prevalence of Knee Pain Among US Adults, National Health Interview Survey, 2002-2010
Jennifer M. Hootman¹, Charles G. Helmick² and Yvonne M. Golightly³, ¹Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ²Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ³Epidemiology, University of North Carolina, Chapel Hill, NC
Trends in prevalence of knee pain among US adults, National Health Interview Survey, 2002-2010 Background/Purpose : Aging of the population as well as the obesity…
Abstract Number: 330 • 2015 ACR/ARHP Annual Meeting
Calf Muscle Adiposity Is Associated with Impaired Physical Performance in Knee OA
Michael Davison¹, Monica R. Maly², Jonathan D. Adachi³ and Karen A. Beattie⁴, ¹School of Medicine, McMaster University, Hamilton, ON, Canada, ²School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, ³Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁴Medicine, McMaster University, Hamilton, ON, Canada
Background/Purpose: Knee osteoarthritis (OA) is a degenerative disease associated with significant muscle weakness and disability. Ectopic fat in the thigh, including intramuscular fat (intraMF; fat…

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