Abstracts tagged "Knee"

Abstract Number: 316 • 2016 ACR/ARHP Annual Meeting
Postural Stability Is Associated with Lower Pain, Lower Stiffness, and Higher Muscle Power Among Adults with Symptomatic Knee Osteoarthritis
Wei Liu¹, Augustine C. Lee², William F. Harvey², Lori Lyn Price³, Jeffrey B. Driban² and Chenchen Wang², ¹Osteopathic Rehabilitation and Biomechanics, 1Edward Via College of Osteopathic Medicine, Auburn, AL, USA, Auburn, AL, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA
Background/Purpose: Postural stability is an indicator of static standing balance and a critical component of physical function and fall prevention among those with knee OA.…
Abstract Number: 2343 • 2016 ACR/ARHP Annual Meeting
A Phase 2, Multi-Center, Randomized, Double-Blind, Active-Controlled, Parallel Group Study to Evaluate the Safety and Dose Effectiveness of Intradermal Injections of Purified Apis Mellifera Toxin to Improve Pain and Physical Function in Patients with Osteoarthritis of the Knee
Douglas R. Schumacher¹, Anna Jakubowska² and Christopher M.H. Kim³, ¹Radiant Research, Columbus, OH, ²Apimeds, Inc., Jungwongu, Seongnam, Gyeonggido, Korea, The Republic of, ³CHA University, Bundanggu, Seongnam, Gyeongghido, Korea, The Republic of
Background/Purpose: This Phase 2a/b trial evaluated the safety and dose effectiveness of honeybee toxin (purified Apis melliferatoxin) injections to improve pain and physical function in…
Abstract Number: 448 • 2016 ACR/ARHP Annual Meeting
Cross-Cultural and Construct Validity of the Animated Activity Questionnaire to Assess Activity Limitations in Patients with Hip and Knee Osteoarthritis in Different Languages
Wilfred Peter¹, Henrica de Vet², Maarten Boers³, Jaap Harlaar⁴, Leo D. Roorda⁵, Rudolf Poolman⁶, Vanessa Scholtes⁷, Martijn P.M. Steultjens⁸, Gordon Hendry⁹, Ewa M. Roos¹⁰, Francis Guillemin¹¹, Maria Grazia Benedetti¹², Lorenzo Cavazutti¹², Antonio Escobar Martinez¹³, Hanne Dagfinrud¹⁴ and Caroline Terwee¹⁵, ¹Department of Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, Netherlands, ²EMGO Institute, VU Medical Centre, Amsterdam, Netherlands, ³Epidemiology & Biostatistics, VU Univ Medical Center F-wing, Amsterdam, Netherlands, ⁴Dep of Rehabilitation Medicine and MOVE research institute, VU University Medical Center, Amsterdam, Netherlands, ⁵Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁶Orthopedic department, Joint Reserach, OLVG, Amsterdam, Netherlands, ⁷Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, ⁸Rehabilitation Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁹School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom, ¹⁰Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, ¹¹University of Lorraine, Nancy, France, ¹²Physical Medicine and Rehabilitation Unit, Istituto Ortopedico Rizzoli, Bologna, Italy, ¹³Health Service Research Network on Chronic Diseases (REDISSEC), Basurto University Hospital, Bilbao, Spain, ¹⁴Department of Rheumatology /National Advosory Unit for Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ¹⁵Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Application of the AAQ in international studies requires good cross-cultural validity, i.e. minimal Differential Item Functioning (DIF) across countries. The aim of this study…
Abstract Number: 2344 • 2016 ACR/ARHP Annual Meeting
Inflammation and Glucose Homeostasis Are Associated with Specific Structural Features Among Adults without Knee Osteoarthritis
Alina Stout¹, Mary Barbe², Charles B. Eaton³, Mamta Amin⁴, Fatimah Al Eid¹, Lori Lyn Price⁵, Bing Lu⁶, Grace H. Lo⁷, Ming Zhang⁸, Timothy E. McAlindon⁹ and Jeffrey Driban⁸, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Temple University School of Medicine, Philadelphia, PA, ³Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁴Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, ⁵Clinical Care Research, Tufts Medical Center, Boston, MA, ⁶Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁷Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ⁸Tufts Medical Center, Boston, MA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Adults with osteoarthritis (OA) have greater glucose concentrations and inflammation. It remains unclear if inflammation and glucose homeostasis are related to specific features of…
Abstract Number: 449 • 2016 ACR/ARHP Annual Meeting
the Animated Activity Questionnaire to Assess Activity Limitations in Patients with Hip and Knee Osteoarthritis: Reliability, Responsiveness, and Interpretation
Wilfred Peter¹, Henrica de Vet², Rudolf Poolman³, Vanessa Scholtes⁴, Dionne Timmermans⁵, Nina Klein Essink⁵ and Caroline Terwee⁶, ¹Amsterdam Rehabilitation Research Centre, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²EMGO Institute, VU Medical Centre, Amsterdam, Netherlands, ³Orthopedic department, Joint Reserach, OLVG, Amsterdam, Netherlands, ⁴Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, ⁵Orthopedics, Joint Research, OLVG, Amsterdam, Netherlands, ⁶Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: A newly developed and (cross-cultural) validated measurement tool, the computerized Animated Activity Questionnaire (AAQ) for assessing activity limitations in hip and knee osteoarthritis (HKOA)…
Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting
Obesity-Related Systemic Inflammation and Knee Synovitis
Devyani Misra¹, Tuhina Neogi², Michael C. Nevitt³, James Torner⁴, Cora E. Lewis⁵ and David T. Felson⁶, ¹Medicine, Section of, BUSM, Boston, MA, ²Clinical Epidemiology, BUSM, Boston, MA, ³Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴University of Iowa, UIowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
Abstract Number: 108 • 2016 ACR/ARHP Annual Meeting
Does Receiving Physical Therapy for Knee Osteoarthritis Impact Downstream Healthcare Utilization?
Allyn Bove¹, Christopher Bise¹, Ken Smith², Julie Fritz³, John Childs⁴, Gerard P. Brennan⁵, J. Haxby Abbott⁶ and G. Kelley Fitzgerald⁷, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Division of Internal Medicine; Institute for Clinical Research Education, University of Pittsburgh, Pittsburgh, PA, ³Department of Physical Therapy, University of Utah, Salt Lake City, UT, ⁴US Army-Baylor University, Schertz, TX, ⁵Rehabilitation Services, Intermountain Healthcare, Murray, UT, ⁶Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, ⁷Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The clinical effectiveness of supervised exercise therapy for individuals with knee osteoarthritis (KOA) is well known. However, it is unclear whether participation in a…
Abstract Number: 1017 • 2016 ACR/ARHP Annual Meeting
Statistical Simulation Using Data from the Foundation for the National Institute of Health/Osteoarthritis Initiative Biomarkers Consortium to Evaluate the Clinical Utility of Prognostic Knee Osteoarthritis Biomarkers in Designing a Knee Osteoarthritis Clinical Trial
Sheng Feng¹, Zheng (Roger) Liu², Feng Hong¹, Jeroen Medema¹, Rajesh Kamath¹ and Marc C. Levesque¹, ¹AbbVie Bioresearch Center, Worcester, MA, ²AbbVie Inc, AbbVie Bioresearch Center, Worcester, MA
Background/Purpose: Development of disease-modifying osteoarthritis drugs (DMOADs) for knee osteoarthritis (OA) has been challenging, partially owing to lack of prognostic biomarkers. Our objective was to…
Abstract Number: 2354 • 2016 ACR/ARHP Annual Meeting
Pharmaceutical Grade Chondroitin Sulfate Improves Knee Osteoarthritis Symptoms More Than Placebo and As Much As Celecoxib: Results of the Chondroitin Vs Celecoxib Vs Placebo Trial (CONCEPT)
J-Y Reginster and CONCEPT Authors' Group, Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium
Background/Purpose: For the assessment of Symptomatic Slow Acting Drugs in Osteoarthritis (SYSADOAs), regulatory Agencies request the assessment of two co-primary endpoints: pain and function. They…
Abstract Number: 333 • 2015 ACR/ARHP Annual Meeting
Smoking and Knee and Hip Osteoarthritis Evolution. Results from the Knee and Hip Osteoarthritis Long-Terme Assessment Cohort
christian roux¹, joel Coste², Bernard Mazieres³, Coralie Roger⁴, eric Fontas⁵, Bruno fautrel⁶, Jacques Pouchot^7,8, Patrice Fardellone^9,10, Anne-Christine Rat^11,12, alain Saraux¹³, Francis Guillemin¹⁴ and Liana Euller Ziegler¹⁵, ¹Rheumatology, LAMHESS laboratory, sofia antipolis university, CHU Pasteur 2, Nice, France, nice, France, ²Biostatistique, Unité INSERM 875, Hotel Dieu, Paris, france, Paris, France, ³Rheumatology department, Hospital Toulouse, france, toulouse, France, ⁴Direction recherche clinique, Hopital universitaire de Nice, nice, France, ⁵Direction recherche clinique, CHU de Nice, france, Nice, France, ⁶rheumatology department, Hospital Pitié Salpétrière, Paris, france, Paris, France, ⁷internal medicine, Hôpital Européen Georges Pompidou, AP-HP, Paris, France, ⁸Paris University, Internal medicine, Paris, France, ⁹Rheumatology, Hopital Nord Amiens, Amiens, France, ¹⁰Department of Rheumatology, Amiens University hospital, Amiens, France, ¹¹CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ¹²Service de Rhumatologie, Nancy-University, Paris Descartes, Metz P Verlaine, EA 4003; Department of clinical epidemiology and evaluation, Nancy University Hospital; Department of rheumatology, Nancy University Hospital, Vandoeuvre les Nancy, France, ¹³Rheumatology Department, CHU la cavale Blanche, brest, france, Brest, France, ¹⁴Department of Clinical Epidemiology and Evaluation, Nancy University Hospital, Nancy-University, EA 4003, Nancy, France, ¹⁵151 rte de St Antoine de Gines, CHU de Nice -Université Nice Sophia Antipolis, Nice, France
Background/Purpose: Relations between smoking and osteoarthritis remains discussed. The protective effect found in previous epidemiological studies has not been confirmed by recent studies and meta…
Abstract Number: 2114 • 2015 ACR/ARHP Annual Meeting
Higher Total Knee Arthroplasty Revision Rates in Black Americans: A Systematic Literature Review and Meta-Analysis
Anne R. Bass¹, Kelly McHugh¹, Kara Fields^2,3, Rie Smethurst⁴, Michael Parks⁵ and Susan M. Goodman¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Medicine/Rheumatology, Hospital for Special Surgery, New York, NY, ³Biostatistics, Hospital for Special Surgery, New York, NY, ⁴Education - Academic Training, Hospital for Special Surgery, New York, NY, ⁵Orthopedics, Hospital for Special Surgery, New York, NY
Background/Purpose: Utilization of total knee arthroplasty (TKA) is lower among blacks than whites in the United States (U.S.), which may be due to blacks' perception…
Abstract Number: 897 • 2015 ACR/ARHP Annual Meeting
Intra-Articular Corticosteroids Are Safe and Have No Major Effect on Structural Progression of Synovitic Knee OA: A 2-Year Randomized Controlled Trial of 3-Monthly Triamcinolone Hexacetonide
Jeffrey Driban¹, Michael P. Lavalley², Lori Lyn Price³, William F. Harvey⁴ and Timothy E. McAlindon⁴, ¹Tufts Medical Center, Boston, MA, ²Biostatistics, Boston University, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Synovitis is common in knees with OA, and is associated with structural progression. Intra-articular corticosteroids are widely used and could reduce knee OA cartilage…
Abstract Number: 2169 • 2015 ACR/ARHP Annual Meeting
Low Education Is Associated with Mortality Among Individuals with Knee and/or Hip OA: The Johnston County Osteoarthritis Project
Rebecca J. Cleveland¹, Todd A. Schwartz², Jordan B. Renner³, Joanne M. Jordan⁴ and Leigh F. Callahan⁴, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²School of Nursing, University of North Carolina, Chapel Hill, NC, ³Radiology, University of North Carolina, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Low socioeconomic status (SES) is associated with an increased risk of death as well as knee and/or hip osteoarthritis (OA). SES and mortality has…
Abstract Number: 949 • 2015 ACR/ARHP Annual Meeting
The Metabolic Syndrome, Its Elements and Knee Osteoarthritis: The Framingham Osteoarthritis (OA) Study
Jingbo Niu¹, Mary Clancy², Piran Aliabadi³ and David T. Felson¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology, BUSM, Boston, MA, ³Radiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Recent studies have suggested an association between knee OA and the metabolic syndrome (MetS), but in these studies the relationship of this syndrome to…
Abstract Number: 2247 • 2015 ACR/ARHP Annual Meeting
Health Care Practices and Care Consumption in a Population Based Cohort of Symptomatic Knee and/or Hip OA Patients
Anne-Christine Rat¹, Alain Saraux², Claudine Gard³, Francis Guillemin⁴ and Bruno Fautrel⁵, ¹Rheumatology, Nancy Teaching Hospital, Nancy, France, ²Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ³APHP, Paris, France, ⁴University of Lorraine, Nancy, France, ⁵GRC08, Sorbonne Universités, UPMC Univ Paris 06, Paris, France, Paris, France
Background/Purpose: Hip and knee OA is frequent and is one of the leading causes of global disability. Population-based data of health care practices and consumption…

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