Abstracts tagged "Knee and osteoarthritis"

Abstract Number: 318 • 2015 ACR/ARHP Annual Meeting
Dual Variable Domain-Immunoglobulin (Dvd-Igâ„¢) Abt-981 Simultaneously and Dose-Dependently Inhibits Interleukin-1 Î‘lpha and -1 Î’eta in Subjects with Knee Osteoarthritis
Susanne X. Wang¹, Ralf Loebbert², Erik Sampson³, Mary Saltarelli¹, Jeroen Medema¹ and Feng Hong³, ¹AbbVie Inc., North Chicago, IL, ²AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, ³AbbVie Inc., Worcester, MA
Background/Purpose: ABT-981 is a novel human Dual-Variable Domain Immunoglobulin (DVD-Ig™) that inhibits interleukin (IL)-1α and IL-1β. The purpose of this study is to evaluate IL-1α…
Abstract Number: 319 • 2015 ACR/ARHP Annual Meeting
Phase 1 Studies of Anti-Interleukin-1 Dual-Variable Domain Immunoglobulin in Healthy Subjects and Patients with Osteoarthritis
Susanne X. Wang¹, Wei Liu¹, Ping Jiang¹, Martin Okun¹, Richard Preston², Carlos J. Lozada², David Carter¹ and Jeroen Medema¹, ¹AbbVie Inc., North Chicago, IL, ²University of Miami Miller School of Medicine, Miami, FL
Background/Purpose: Interleukin (IL)-1 is a catabolic cytokine that plays an important role in pathogenesis and progression of osteoarthritis (OA). Two phase 1 clinical trials investigated…
Abstract Number: 1088 • 2015 ACR/ARHP Annual Meeting
Effect of Training on Knee Torsional Stiffness and Its Relationship to Tibial Compressive and Anterior Shear Forces in Recreational Female Runners
Bhushan Thakkar¹ and D. S. Blaise Williams III², ¹PHYSICAL THERAPY, VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA, ²Physical Therapy, Virginia Commonwealth University, Richmond, VA
Background/Purpose: 42 million Americans participate annually in running. In 2014, the half marathon was the most popular distance with a total of 61% females (1.2…
Abstract Number: 2234 • 2014 ACR/ARHP Annual Meeting
Safety and Efficacy of Liposome Intra-Articular Injection in Moderate Knee Osteoarthritis. a Prospective Randomized Double-Blinded Study
Leonid Kandel¹, Yaniv Dolev², Rachel Shimonov¹, Gurion Rivkin¹, Meir Liebergall¹, Yoav Mattan¹ and Xavier Chevalier³, ¹Orthopedic Surgery Department, Hadassah Medical Center, Jerusalem, Israel, ²Moebius Medical Ltd., Tel Aviv, Israel, ³Department of Rheumatology Hopital Henri Mondor, Créteil, France
Background/Purpose: Bio-lubrication is a prerequisite for proper joint mobility and is crucial for prevention of degradative changes of the joint. Phospholipids are components of the…
Abstract Number: 2144 • 2013 ACR/ARHP Annual Meeting
Prevention Of Radiological Progression In Patients With Primary Knee Osteoarthritis With Strontium Ranelate
Jean-Yves Reginster¹, Roland Chapurlat², Francis Berenbaum³, P. Nash⁴, O. Zamani⁵, Martine Cohen-Solal⁶, Gerolamo Bianchi⁷, Jaime Branco⁸, F. Navarro⁹ and Cyrus Cooper¹⁰, ¹Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, ²INSERM UMR 1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, ³Rheumatology, AP-HP, St Antoine Hospital, Paris, France, ⁴University of Queensland, Brisbane, Australia, ⁵Rheumazentrum Favoriten, Wien, Austria, ⁶Rhumatologie A, INSERM U606 Hôpital Lariboisière, Centre Viggo Petersen, Paris, France, ⁷Div Reumatologia, ASL3 Genovese, Genoa, Italy, ⁸UNL/Rheumatology Department, Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, ⁹UGC de Reumatologia, University Hospital Virgen Macarena, Sevilla, Spain, ¹⁰MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom
Prevention of radiological progression in patients with primary knee osteoarthritis with Strontium Ranelate Background/Purpose: Strontium ranelate (SrRan) has demonstrated a structure-modifying activity with symptomatic improvement in…
Abstract Number: 2147 • 2013 ACR/ARHP Annual Meeting
Effect Of Fish Oil On Structural Progression In Knee Osteoarthritis: A Two Year Randomized, Double-Blind Clinical Trial Comparing High Dose With Low Dose
Catherine L. Hill¹, Graeme Jones², Susan Lester³, Ruth Battersby¹, Tanya Fedorova⁴, Kristen Hynes⁵, Susanna Proudman⁶, Leslie G. Cleland⁶ and Lyn March⁷, ¹Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Rheumatology Unit, Queen Elizabeth Hospital, Woodville South, Australia, ⁴Rheumatology Royal North Shore Hospital, University of Sydney Institute of Bone and Joint Research, St Leonards, Australia, ⁵Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ⁶Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, ⁷Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia
Background/Purpose: Fish oil is widely used for the symptomatic treatment of osteoarthritis. However, its effect on cartilage volume has not previously been investigated in an…
Abstract Number: 1128 • 2013 ACR/ARHP Annual Meeting
Validation Of a Rapid, Quantitative Method Of Magnetic Resonance Imaging-Detected Osteoarthritis-Related Bone Marrow Lesions In The Patellofemoral Joint
Charles Ratzlaff¹ and Jeffrey W. Duryea², ¹Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ²Dept of Radiology, Brigham & Women, Boston, MA
Background/Purpose : We recently developed an efficient semi-automated measure of tibial and femoral BML volume and validated it against the Whole-Organ Magnetic Resonance Imaging Score…
Abstract Number: 257 • 2013 ACR/ARHP Annual Meeting
The Association Of Proximal Tibia Shape With Sex: The Osteoarthritis Initiative
Barton L. Wise¹, Felix Liu², Neeta Parimi³, John A. Lynch⁴, Yuqing Zhang⁵, Lisa Kritikos⁶ and Nancy E. Lane¹, ¹Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ²University of California at San Francisco, San Francisco, CA, ³California Pacific Medical Center Research Institute, San Francisco, CA, ⁴Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁵Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁶UC Davis School of Medicine, Sacramento, CA
Abstract for Submission to OARSI December 2012 Background/Purpose: Knee osteoarthritis (OA) manifests disproportionately in women and the etiology remains unclear. Bone shape has been…
Abstract Number: 1098 • 2012 ACR/ARHP Annual Meeting
Knee Osteoarthritis and Frailty in Older Adults: Findings From the Multicenter Osteoarthritis Study and Osteoarthritis Initiative
Devyani Misra¹, Michael C. Nevitt², Cora E. Lewis³, James Torner⁴, David T. Felson⁵ and Tuhina Neogi⁶, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ³Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, ⁴Epidemiology, University of Iowa, Iowa City, Iowa City, IA, ⁵Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁶Clinical Epidemiology, Boston University School of Medicine, Boston, MA
Background/Purpose: Both knee osteoarthritis (OA) and the frailty syndrome affect older adults and both are associated with functional limitation and disability. Frailty in elders is…
Abstract Number: 914 • 2012 ACR/ARHP Annual Meeting
Prognosis for the Year 2030: The Consultation Prevalence of Osteoarthritis in Sweden May Increase by 50%
Aleksandra Turkiewicz¹, Ingemar F. Petersson², Jonas Björk³, Leif E. Dahlberg¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Lund University, Lund, Sweden, ³Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden, Lund, Sweden
Background/Purpose: To project the future prevalence of knee and hip osteoarthritis (OA) leading to doctor consultation. Methods: The Skåne Health Care Register is a legislative,…
Abstract Number: 913 • 2012 ACR/ARHP Annual Meeting
Consultation Prevalence of Osteoarthritis in Southern Sweden
Aleksandra Turkiewicz¹, Ingemar F. Petersson², Jonas Björk³, Leif E. Dahlberg¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Lund University, Lund, Sweden, ³Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden, Lund, Sweden
Background/Purpose: To estimate the prevalence of subjects with osteoarthritis (OA) having led to doctor consultation. Methods: The Skåne Health Care Register (SHCR) is a legislative,…
Abstract Number: 798 • 2012 ACR/ARHP Annual Meeting
A Rich Description of Clinical Exam Features in Patients with Knee Osteoarthritis and Their Correlation with Functional Outcomes
Maura D. Iversen¹, Kelli Sylvester², Abigail Grader², Michelle A. Frits³, Marie Boneparth⁴, Megan Whitmore⁴, Jane Lucas⁵, Fatima Shahzad⁶, Jeffrey B. Driban⁶ and Chenchen Wang⁷, ¹Northeastern University, Department of Physical Therapy, and Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²Department of Physical Therapy, Northeastern University, Department of Physical Therapy, Northeastern University, Boston, MA, ³Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁴Physical Therapy, Tufts Medical Center, Boston, ⁵Back Bay Physical Therapy, Boston, ⁶Rheumatology, Tufts Medical Center, Boston, MA, ⁷Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Assessments of symptomatic knee osteoarthritis (KOA) rely on physical measures for clinical decision-making. However, there is limited literature on the association between examination procedures…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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