ACR Meeting Abstracts

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Abstracts tagged "Juvenile idiopathic arthritis"

  • Abstract Number: 0362 • ACR Convergence 2023

    Adverse Childhood Experiences Are Associated with Disease Outcomes in Youth with Juvenile Idiopathic Arthritis

    Danielle Bullock1, Ilir Agalliu2, Evin Rothschild2, Kaveh Ardalan3, Erica Lawson4, Natoshia Cunningham5, William Soulsby4, Nicole Reitz6, Laura Bouslaugh7, Anna Diggs8, Elizabeth Kessler9, Sara Kramer1, Bhupinder Nahal4, Cassandra Davis10, Ashley Kemp1, Riley O'Connor1, Tiffany Chinn4, Kathy Nguyen4, Paige Hill1 and Tamar Rubinstein11, 1University of Minnesota, Minneapolis, MN, 2Albert Einstein College of Medicine, Bronx, NY, 3Duke University School of Medicine, Durham, NC, 4University of California San Francisco, San Francisco, CA, 5Michigan State University, Grand Rapids, MI, 6CARRA, Allendale, MI, 7CARRA, Washington, DC, 8CARRA, Tipton, MO, 9Spectrum Health, Grand Rapids, MI, 10University of Utah, Salt Lake City, UT, 11Albert Einstein College of Medicine, Children's Hospital at Montefiore, White Plains, NY

    Background/Purpose: Adverse childhood events (ACEs) are common in children. ACEs are various stressors, including, but not limited to parental incarceration or food and housing insecurity.…
  • Abstract Number: 0761 • ACR Convergence 2023

    EULAR / PreS Recommendations for the Diagnosis and Management of Systemic Juvenile Idiopathic Arthritis (sJIA) and Adult Onset Still’s Disease (AOSD)

    Bruno Fautrel1, STEPHANE MITROVIC2, Arianna De Matteis3, Sara Bindoli4, Jordi Anton5, Alexandre Belot6, Claudia Bracaglia3, Tamas Constantin7, Lorenzo Dagna8, Alessandro de Bartolo9, Eugen Feist10, Dirk Foell11, Marco Gattorno12, Sophie Georgin-Lavialle13, Roberto Giacomelli14, Alexei Grom15, Yvan Jamilloux16, Katerina Laskari17, Calin Lazar18, Francesca Minoia19, Peter Nigrovic20, Filipa Oliveira Ramos21, Seza Ozen22, Pierre Quartier Dit Maire23, Piero Ruscitti24, Erdal Sag25, Sinisa Savic26, Marie-Elise Truchetet27, Sebastiaan Vastert28, Tanita Wilhelmer29, Carine Wouters30, Loreto Carmona31 and Fabrizio De Benedetti32, 1Sorbonne Université APHP, Paris, France, 2Pitie Salpetriere Hospital, Sorbonne University, APHP, Paris, France, 3IRCCS Ospedale Pediatrico Bambino Gesu', Rome, Italy, 4Rheumatology Unit, department of Medicine,University of Padova, Padova, Italy, 5Hospital Sant Joan de Déu, Pediatric Rheumatology Department, Universitat de Barcelona, Barcelona, Spain, 6Hospices Civils de Lyon, Collonges au mont d'or, France, 7Semmelweis University, Budapest, Hungary, 8Ospedale San Raffaele, Milano, Italy, 9PReS Patient Research Partner, Milan, Italy, 10Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Germany, 11University Hospital Münster, Münster, Germany, 12UOC Reumatologia e Malattie Autoinfiammatorie, Genoa, Italy, 13AP-HP, Tenon hospital, Paris, France, 14Policlinico Universitario Campus Bio-Medico, Roma, Italy, 15Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 16Hospices Civils de Lyon, Lyon, France, 17Athens University Medical School, Athens, Greece, 18University of Medicine and Pharmacy, Cluj-Napoca, Romania, 19Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy, 20Boston Children's Hospital, Boston, MA, 21Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal, 22Hacettepe University Medical Faculty, Ankara, Turkey, 23Necker Hospital, Paris Cedex 15, France, 24University of L'Aquila, L'Aquila, Italy, 25Department of Pediatric Rheumatology, Hacettepe University, Ankara, Turkey, 26Leeds University, Leeds, United Kingdom, 27Bordeaux University Hospital, Bordeaux, France, 28University Medical Center Utrecht, Utrecht, Netherlands, 29EULAR Patient Research Partner, Bludenz, Austria, 30Leuven University, Leuven, Belgium, 31Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, 32Bambino Gesu Children's Hospital, Division of Rheumatology, Rome, Italy

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD) are supposed to be age counterparts of the same disease, but no consensus has…
  • Abstract Number: 1707 • ACR Convergence 2023

    PD1-Expressing Regulatory T Cells Found in Inflamed Joints Suppress Tph Cell-B Cell Interactions

    Ki Pui Lam1, Amélie M Julé1, Claudia Harris2, Maria Taylor1, Maryrose Hahn2, Laurie A Ohlms3, Pui Lee2, Margaret Chang4, Talal Chatila5, Peter Nigrovic4 and Lauren Henderson4, 1Division of Immunology, Boston Children’s Hospital, Boston, MA, 2Division of Immunology, Boston Children's Hospital, Boston, MA, 3Department of Otolaryngology & Communication Enhancement, Boston Children’s Hospital, Boston, MA, 4Boston Children's Hospital, Boston, MA, 5Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: T peripheral helper (Tph) cells promote B cell maturation and the generation of antibodies in the inflamed joints of adults with seropositive rheumatoid arthritis…
  • Abstract Number: 016 • 2023 Pediatric Rheumatology Symposium

    Gene Expression Changes in Polyarticular Juvenile Idiopathic Arthritis Following Tofacitinib Treatment

    Esraa Eloseily1, Alex Pickering2, Sanjeev Dhakal3, Alexei Grom3, Hermine Brunner3 and Sherry Thornton4, 1Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnti, OH, 2Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital, Cincinnati, OH

    Background/Purpose: Despite advances in the understanding of juvenile idiopathic arthritis (JIA) pathophysiology, personalized treatments informed by gene transcriptomic profiles remain elusive. We aimed toexamine the…
  • Abstract Number: 113 • 2023 Pediatric Rheumatology Symposium

    Proportion of Patients with a Polyphasic Disease Course in Systemic-onset Juvenile Idiopathic Arthritis May Be Higher in the Age of Cytokine Inhibitors

    Itay Marmor1, Rotem Semo Oz2, Amir hendel3, Guy Hazan4, Kevin Baszis5, Anthony French5, Cuoghi Edens6, Irit Tirosh7, Yonatan Butbul Aviel8, Liora Harel9 and Gil Amarilyo10, 1Dana-Dwek Children's Hospital, Hod Hasharon, Israel, 2Sheba medical center, Herzelyia, Israel, 3Tel Aviv University, Tel Aviv, Israel, 4Soroka University Medical Center, Be'er Sheva, Israel, 5Washington University School of Medicine, St Louis, MO, 6University of Chicago, Chicago, IL, 7Sheba Medical Center, Savyon, Israel, 8Rambam Medical center, Haifa, Israel, 9Scheiders Children Medical Center of Israel, Petah-Tiqva, Israel, 10Schneider Children's Medical Center of Israel, Petach Tikva, Israel

    Background/Purpose: Systemic-onset juvenile idiopathic arthritis (sJIA) is a pediatric autoinflammatory condition, known for significant variability between patients in its severity and long-term outcomes. The classification…
  • Abstract Number: 017 • 2023 Pediatric Rheumatology Symposium

    Potential Uveitic Biomarkers in Tears of Children with Juvenile Idiopathic Arthritis: A Pilot Study

    Tiffany Nguyen1, Ilaria Maccora1, Mekibib Altaye1, Wendy Haffey2, Theresa Hennard1, Alyssa Sproles1, Sherry Thornton1, Virginia Miraldi Utz1, Ken Greis2 and Sheila Angeles-Han1, 1Cincinnati Children's Hospital, Cincinnati, OH, 2University of Cincinnati, Cincinnati, OH

    Background/Purpose: Children diagnosed with oligoarticular juvenile idiopathic arthritis (JIA), the most commonly diagnosed subset of chronic arthritis, are at increased risk of developing uveitis. Known…
  • Abstract Number: 115 • 2023 Pediatric Rheumatology Symposium

    Development of an Electronic Clinical Phenotype to Identify Potential Study Subjects with Juvenile Arthritis

    Alysha Taxter1, Marc Natter2, Min-Lee Chang2, Laura Schanberg3, Valarie Morrow4, Eveline Wu5, Tedryl Bumpass4, Alex Fist4, Meg Waite6, Vincent Del Gaizo7, Melanie Kohlheim7 and CARRA Registry Investigators7, 1Nationwide Children's Hospital, Columbus, OH, 2Boston Children's Hospital, Boston, MA, 3Duke University Medical Center, Durham, NC, 4Duke University, Durham, NC, 5UNC Chapel Hill, Chapel Hill, NC, 6Boston Children's Hospital, Boston, MA, 7CARRA, Washington, DC

    Background/Purpose: The LIMIT-JIA trial is the first study of the use of biologic therapy to prevent disease extension in children with newly diagnosed, uncomplicated, oligo-articular…
  • Abstract Number: 019 • 2023 Pediatric Rheumatology Symposium

    Developing Standard Improvement Curves for Disease Activity, Pain and Quality of Life in Children with Newly Diagnosed Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Amieleena Chhabra1, Matt Berkiwitz2, Thomas Loughin2, Lori Tucker3, Giles Boire4, Karine Toupin-April5, Dax Rumsey6, Michelle Batthish7, Linda Li8, Adam Huber9, Brian Feldman10, Jean-Phillippe Proulx-Gauthier11, Ciaran Duffy12, Paul Dancey13, Gordon Soon14, Heinrike Schmeling6 and Jaime Guzman15, 1University of British Columbia, Vancouver, BC, Canada, 2Simon Fraser University, Burnaby, BC, Canada, 3BC Children's Hospital, Vancouver, BC, Canada, 4Sherbrooke University, Sherbrooke, QC, Canada, 5University of ottawa, Ottawa, ON, 6University of Alberta, Edmonton, AB, Canada, 7McMaster Children's Hospital, Hamilton, ON, Canada, 8Arthritis research, Vancouver, BC, Canada, 9University of Nova Scotia, Halifax, NS, Canada, 10Hospital for Sick Children / University of Toronto, Toronto, ON, Canada, 11Université Laval, Québec, QC, Canada, 12Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, Canada, 13Université de Montréal, Montreal, QC, Canada, 14University of Toronto, Toronto, ON, 15University of British Columbia, Vancouver, BC

    Background/Purpose: When a diagnosis of juvenile idiopathic arthritis (JIA) is made, many parents are shocked to find out that arthritis occurs in children and may…
  • Abstract Number: 118 • 2023 Pediatric Rheumatology Symposium

    Serum Hepatocyte Growth Factor in Children with Juvenile Idiopathic Arthritis

    Natalia Shevchenko and Olga Pavlova, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine

    Background/Purpose: Only limited data are available on the risk of liver fibrosis in patients with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) on long-term…
  • Abstract Number: 037 • 2023 Pediatric Rheumatology Symposium

    Transcriptional Analysis of CD14+ Monocytes During Macrophage Activation Syndrome Highlights Role for Interferons and RNA Sensing in Monocytes

    Susan Canny1, Hannah DeBerg2, Griffin Gessay2, Ailing Lu3, Mary Eckert1, Andrea La Bella4, Susan Shenoi5, Joyce Hui-Yuen6, Betsy Barnes7 and Jessica Hamerman2, 1Seattle Children's Hospital, Seattle, WA, 2Benaroya Research Institute, Seattle, WA, 3Feinstein Institutes for Medical Research, Manhasset, NY, 4Northwell Health, Cohen Children's Medical Center, New Hyde Park, NY, 5Seattle Children's Hospital, Seattle, WA, 6Cohen Children's Medical Center, Northwell Health, Lake Success, New York; Center for Autoimmune, Musculoskeletal, and Hematopoietic Diseases Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, 7Center for Autoimmune, Musculoskeletal, and Hematopoietic Diseases Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY

    Background/Purpose: Macrophage activation syndrome (MAS), a form of secondary hemophagocytic lymphohistiocytosis (HLH), is a potentially fatal complication of rheumatic diseases. MAS is a dysfunctional hyperinflammatory…
  • Abstract Number: 119 • 2023 Pediatric Rheumatology Symposium

    Laser Flare Photometery in the Pediatric Rheumatology Clinic as a Screening Tool for Juvenile Idiopathic Arthritis Associated Uveitis

    Kaleo Ede1, Michael Shishov2, Elisa Wershba2, Nikita Goswami2, Sabrina Gorry2, Malin Jospeh2, Lucia Mirea2 and James O'neil2, 1Phoenix Children's Hosptial; University of Arizona College of Medicine- Phoenix, Phoenix, AZ, 2Phoenix Children's Hospital, Phoenix, AZ

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most common chronic rheumatic disease in childhood, affecting 1 to 22 per 100,000 children. JIA-associated uveitis is known…
  • Abstract Number: 038 • 2023 Pediatric Rheumatology Symposium

    HLA-DRB1*15 Alleles in Systemic Juvenile Idiopathic Arthritis with Lung Disease and Macrophage Activation Syndrome in Italy

    Claudia Bracaglia1, Manuela Pardeo1, Maria Troiano2, Giuseppe Testa2, Ivan Caiello1, Arianna De Matteis3, Matteo Trevisan1, Franco Locatelli4, Marco Andreani2 and Fabrizio De Benedetti1, 1Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy, 2Laboratory of Transplant Immunogenetics, Department of Haematology/Oncology, Cell and Gene, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Lazio, Italy, 3Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesu', Roma, Italy, 4Ospedale Pediatrico Bambino Gesù, Department of Hematology/Oncology, Cell and Gene Therapy, Roma, Italy

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is characterized by unique clinical features and it is considered as a polygenic autoinflammatory disease. Macrophage activation syndrome (MAS)…
  • Abstract Number: 122 • 2023 Pediatric Rheumatology Symposium

    Juvenile Arthritis in Minnesota: Geospatial Variability and Environmental Exposures in Juvenile Idiopathic Arthritis

    Colleen Correll1, Austin Rau2 and Jesse Berman2, 1University of Minnesota, Minneapolis, MN, 2University of Minnesota, Minneapolis

    Background/Purpose: It is widely accepted that juvenile idiopathic arthritis (JIA) is caused by a combination of genetic and environmental factors, but the potential environmental triggers…
  • Abstract Number: 039 • 2023 Pediatric Rheumatology Symposium

    Towards the Definition of Cutoff Values for Disease Activity States in Systemic JIA Using the Systemic Juvenile Arthritis Disease Activity Score

    Ana Isabel Rebollo-Giménez1, Yulia Vyzhga2, Luca Carlini3, Silvia Rosina4, Elisa Patrone1, Maria Katsikas5, Claudia Magalhaes6, Dalia El-Ghoneimy7, Yasser El Miedany8, Raju Khubchandani9, Priyankar Pal10, Gabriele Simonini11, Giovanni Filocamo12, Maurizio Gattinara13, Fabrizio De Benedetti14, Davide Montin15, Adele Civino16, Muatasem Alsuweiti17, Valda Stanevicha18, Vyacheslav Chasnyk19, Ekaterina Alexeeva20, Sulaiman M Al-Mayouf21, Soamarat Vilaiyuk22 and Angelo Ravelli23, 1IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Infiammatorie, Genova, Italy, 2IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattia Infiammatorie, Genova, Italy, 3IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genova, Italy, 4IRCCS Istituto Giannina Gaslini, Genova, Italy, 5Hospital de Pediatria Juan P. Garrahan, Department of Immunology/Rheumatology, Buenos Aires, Argentina, 6São Paulo State University, Pediatric Rheumatology Division, Botucatu, Brazil, 7Children's Hospital, Ain Shams University, Pediatric Allergy, Immunology and Rheumatology Unit, Cairo, Egypt, 8Ain Shams University, Department of Rheumatology and Rehabilitation, Cairo, Egypt, 9Jaslok Hospital and Research Centre, Department of Paediatrics, Mumbai, India, 10Institute of Child Health, Pediatric medicine, Kolkata, India, Kolkata, India, 11IRCCS Meyer Children’s Hospital, Rheumatology Unit, Florence, Italy, 12Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Pediatric Rheumatology, Milano, Italy, 13Istituto Gaetano Pini, Rheumatology Unit, Milano, Italy,, Genova, 14Division of Rheumatology, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy, 15Regina Margherita Children Hospital, Immunology and Rheumatology Unit, Turin, Italy, 16Ospedale Vito Fazzi, Paediatric Immunology/Rheumatology Service, Lecce, Italy, 17King Hussein Medical Center, Department of Pediatrics - Pediatric Allergy, Immunology & Rheumatology Clinic, Amman, Jordan, 18University Children Hospital, Department of Pediatrics, Riga, Latvia, 19Saint-Petersburg State Pediatric Medical University, Department of Hospital Pediatrics, St. Petersburg, Russia, 20Federal State Autonomous Institution “National Medical Research Center of Children's Health”, Ministry of Health of the Russian Federation, Moscow, Russia, 21King Faisal Specialist Hospital & Research Center, Alfaisal University, Department of Pediatric Rheumatology, Riyadh, Saudi Arabia, 22Mahidol University Faculty of Medicine, Ramathibodi Hospital Department of Pediatrics, Bangkok, Thailand, 23IRRCS Istituto Giannina Gaslini and Università degli Studi di Genova, Genova, Italy

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) accounts up to 15% of all patients with JIA and is distinctfrom the other disease categories due to the…
  • Abstract Number: 124 • 2023 Pediatric Rheumatology Symposium

    JIA-Associated TMJ Arthritis, Idiopathic Condylar Resorption or Anterior Disc Displacement – a Care Provider Survey

    Daria Sosna1, Nancy Pan2, Shelly Abramowicz3, Mara Becker4, Melissa Lerman5, Cory Resnick6, Tova Ronis7, Matthew Stoll8, Peter Stoustrup9, Marinka Twilt10, CARRA Registry Investigators11 and For TMJaw12, 1Alberta Children's Hospital/University of Calgary, Calgary, AB, Canada, 2Hospital for Special Surgery, New York, NY, 3Emory University, Atlanta, GA, 4Duke University Medical Center/Duke Clinical Research Institute, Durham, NC, 5Children's Hospital of Philadelphia, Philadelphia, PA, 6Harvard University, Boston, MA, 7Children's National Hospital, Chevy Chase, MD, 8University of Alabama at Birmingham, Birmingham, AL, 9Aarhus University, Aarhus, Denmark, 10Alberta Children's Hospital, Calgary, AB, Canada, 11CARRA, Washington, DC, 12TMJaw, Fullerton, CA

    Background/Purpose: The temporomandibular joint (TMJ) can be affected in juvenile idiopathic arthritis (JIA) patients of any age or subtype. There have been reports of isolated…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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