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Abstracts tagged "Juvenile idiopathic arthritis"

  • Abstract Number: 0874 • ACR Convergence 2022

    A Tale of Many Canadas: Associations of Ethnicity with Juvenile Idiopathic Arthritis Categories and Disease Severity at Presentation in a Multicultural Universal Healthcare Setting: Results from ReACCh-Out

    Stephanie Wong1, Lori Tucker2, Kristin Houghton3, David Cabral4, Mercedes Chan2, Ross Petty3, Andrea Human2, Kimberly Morishita3, Rae Yeung5, Kiem Oen6, Ciaran Duffy7, Roberta Berard8, Gaelle Chedeville9, Thomas Loughin10, Matthew Berkowitz10 and Jaime Guzman11, 1University of British Columbia, Vancouver, BC, Canada, 2British Columbia Children's Hospital, Vancouver, BC, Canada, 3University of British Columbia - Vancouver, Vancouver, BC, Canada, 4BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 5The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 6University of Manitoba, Toronto, ON, Canada, 7University of Ottawa, Ottawa, ON, Canada, 8London Health Sciences Centre, London, ON, Canada, 9McGill University, Montréal, QC, Canada, 10Simon Fraser University, Vancouver, BC, Canada, 11University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: The distribution of Juvenile Idiopathic Arthritis (JIA) categories and disease severity at presentation vary across countries, however it is unclear how much of this…
  • Abstract Number: 2209 • ACR Convergence 2022

    Efficacy of Secukinumab in Enthesitis-related Arthritis and Juvenile Psoriatic Arthritis Subtypes of Juvenile Idiopathic Arthritis: Results from a Randomized, Phase 3 Study

    Hermine Brunner1, Elena Chertok2, Joke Dehoorne3, Gerd Horneff4, Tilmann Kallinich5, Ingrid Louw6, Maria Alessio7, Sandrine Compeyrot-Lacassagne8, Bernard Lauwerys9, Neil Martin10, Katherine Marzan11, W Patrick Knibbe12, Ruvie Martin13, Xuan Zhu14, sarah whelan15, Luminita Pricop16, Daniel Lovell17, Alberto Martini18 and Nicola Ruperto19, 1Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH, 2Voronezh State Medical University, Voronezh, Russia, 3University Hospital Gent, Gent, Belgium, 4Pediatrics, Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin, Germany, 5Charité - Universitätsmedizin Berlin, Nuremberg, Germany, 6Panaroma Medical Centre, Cape Town, South Africa, 7Policlinico Federico II di Napoli, Napoli, Italy, 8Great Ormond Street Hospital for Children, London, United Kingdom, 9Cliniques Universitaires Saint-Luc, Brussels, Belgium, 10Royal Hospital for Children, Glasgow, Scotland, United Kingdom, 11Children's Hospital Los Angeles, Los Angeles, CA, 12St. Luke's Hospital System, Meridian, ID, 13Novartis Pharmaceutical Corporation, East Hanover, NJ, 14Novartis Pharmaceuticals Corporation, Basking Ridge, NJ, 15Novartis Ireland Ltd, Crumlin, Dublin, Ireland, 16Novartis Pharmaceuticals Corporation, East Hanover, NJ, 17Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 18Istituto Giannina Gaslini, Genova, Italy, 19IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) represent pediatric counterparts of adult non-radiographic axial spondyloarthritis and psoriatic…
  • Abstract Number: 0853 • ACR Convergence 2022

    Reliability of MRI Lesions Comprising the Preliminary OMERACT Juvenile Idiopathic Arthritis MRI Score (OMERACT JAMRI-SIJ): What Is the Impact of Systematic Reader Calibration?

    Walter P Maksymowych1, Nisha Varma2, Arthur Meyers3, Jennifer Stimec4, Nikolay Tzaribachev5, Jonathan Akikusa6, Tarimobo Otobo4, Marion von Rossum7, Andrea Doria4 and Nele Herregods8, 1Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2Department of Paediatric Radiology, The Royal Children's Hospital Melbourne, Melbourne, Australia, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Department of Diagnostic Imaging, SickKids, University of Toronto, Toronto, ON, Canada, 5PRI Research Institute, Bad Bramstedt, Germany, 6Rheumatology Service, Royal Children’s Hospital, Melbourne, Melbourne, Australia, 7Emma Children’s Hospital, Dept Pediatrics, Amsterdam University Medical Centers, Amsterdam, Netherlands, 8Ghent University Hospital, Ghent, Belgium

    Background/Purpose: The evaluation of the sacroiliac joints (SIJ) in children with Juvenile Idiopathic Arthritis (JIA) increasingly relies on the use of MRI since radiography is…
  • Abstract Number: 0875 • ACR Convergence 2022

    Predictive Biomarkers of Tofacitinib Response and Disease Activity in Juvenile Idiopathic Arthritis Subtypes: A Longitudinal Study

    Ekemini Ogbu1, Sherry Thornton2, Alyssa Sproles2, Alexei Grom3, Sanjeev Dhakal4, Bin Huang5 and Hermine Brunner6, 1Cincinnati Children's Hospital Medical Center, Atlanta, GA, 2Cincinnati Children's Hospital, Cincinnati, OH, 3Divisions of Rheumatology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Cincinnati Children's Hospital Medical Center, Cinciannati, OH, 6Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH

    Background/Purpose: Tofacitinib has been shown to improve disease activity of several subtypes of Juvenile Idiopathic Arthritis (JIA). No known biomarkers to date predict JIA improvement…
  • Abstract Number: 2210 • ACR Convergence 2022

    Baricitinib in Juvenile Idiopathic Arthritis: A Phase 3, Double-Blind, Placebo-Controlled, Withdrawal, Efficacy and Safety Study

    Athimalaipet Ramanan1, Pierre Quartier Dit Maire2, Nami Okamoto3, Gabriella Meszaros4, Joana Araujo4, Zhongkai Wang4, Ran Liao4, Brenda Crowe4, Xin Zhang4, Rodney Decker4, Stuart Keller4, Hermine Brunner5 and Nicola Ruperto6, 1Bristol Royal Hospital for Children, Bristol, United Kingdom, 2Necker hospital, Paris Cedex 15, France, 3Osaka Medical College, Takatsuki-city, Japan, 4Eli Lilly and Company, Indianapolis, IN, 5Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH, 6IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Baricitinib is a JAK1/2 selective inhibitor approved for the treatment of rheumatoid arthritis. Juvenile idiopathic arthritis (JIA) is a group of diseases characterized by…
  • Abstract Number: 0854 • ACR Convergence 2022

    Outcome of Uveitis in Juvenile Idiopathic Arthritis and Spondyloarthritis Patients – a 5-year Follow up Study

    Filipe Pinheiro1, Mariana Leuzinger-Dias2, Bruno Fernandes3, Diogo Fonseca4, Joana Vilaça5, Luís Figueira6 and Iva Brito7, 1Rheumatology Department, Centro Hospitalar Universitário de São João, Porto, Portugal, 2Ophtalmology Department, Centro Hospitalar Universitário de São João, Porto, Portugal, 3Rheumatology Deparment, Centro Hospitalar e Universitário de São João, Porto, Portugal, 4Rheumatology Department, Centro Hospitalar de Vila Nova de Gaia / Espinho, Vila Nova de Gaia, Portugal, 5Paediatrics Department, Hospital de Braga, Braga, Portugal, 6Ophthalmology Department, Centro Hospitalar Universitário de São João, Porto, Portugal, 7Pediatric and Young Adult Rheumatology Unit, Centro Hospitalar Universitário de São João, Porto, Portugal

    Background/Purpose: Uveitis is a frequent complication of juvenile idiopathic arthritis (JIA) and juvenile spondyloarthritis (jSpA), and diagnosis is often challenging. The importance of uveitis relates…
  • Abstract Number: 0876 • ACR Convergence 2022

    Investigation of Predictive Factors for Active Disease Status Within 24 Months of Juvenile Idiopathic Arthritis Diagnosis

    Erin Balay1 and Susan Shenoi2, 1University of Washington, Seattle Children's Hospital, Seattle, WA, 2Seattle Children's Hospital and Research Center / University of Washington, Seattle, WA

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most common rheumatologic disease in children. JIA disease course and prognosis varies significantly between its seven categories, and…
  • Abstract Number: 2211 • ACR Convergence 2022

    Identification of Plasma Metabolomic Biomarkers of Juvenile Idiopathic Arthritis

    Amar Kumar1, Joshua Tartarian2, Valentina Shakhnovich3, Carl Langefeld4, Daniel Lovell5, Susan Thompson6, Mara Becker7 and Ryan Funk8, 1University of Kansas, Kansas City, KS, 2University of Kansas Medical Center, Kansas City, KS, 3University of Missouri-Kansas City School of Medicine & Children’s Mercy Kansas City, Kansas City, MO, 4Wake Forest School of Medicine, Winston Salem, NC, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Cincinnati Children's Hospital Medical Center/Univ of Cincinnati College of Medicine, Blue Ash, OH, 7Duke University Medical Center/Duke Clinical Research Institute, Durham, NC, 8University of Kansas, Leawood, KS

    Background/Purpose: Identification of disease and therapeutic biomarkers remains a barrier to the early diagnosis of and initiation of effective therapy for juvenile idiopathic arthritis (JIA).…
  • Abstract Number: 0855 • ACR Convergence 2022

    Change in Short Term Outcomes Following Tolerated Disease Activity Level for Individuals with Juvenile Idiopathic Arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry

    Melissa Mannion1, Fenglong Xie1, Timothy Beukelman1, Jeffrey Curtis2 and , for the CARRA Registry Investigators3, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Hoover, AL, 3CARRA, Washington, DC

    Background/Purpose: Current recommendations suggest treatment escalation for juvenile idiopathic arthritis (JIA) until the disease activity target is reached, ideally inactive or low disease activity. Our…
  • Abstract Number: 0877 • ACR Convergence 2022

    Neutrophils Extracellular Traps Formation May Serve as a Biomarker for Disease Activity in Oligoarticular Juvenile Idiopathic Arthritis

    Merav Heshin-Bekenstein1, Szilvia Baron2, Grant Schulert3, Anna Shusterman4, Rachel Shukrun4, Yoav Binenbaum4 and Ronit Elhasid5, 1Dana Dwek Children's Hospital, Tel Aviv Medical Center Israel, Binyamina, Israel, 2Pediatric Hemato-Oncology Research Laboratory, Tel Aviv Medical Center, Tel Aviv, Israel, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Tel Aviv Medical Center, Tel Aviv, Israel, 5Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv, Israel

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children, causing significant morbidity. Despite the dramatic improvement in treatment, many patients…
  • Abstract Number: 2213 • ACR Convergence 2022

    Multi-omic Analysis of Macrophage Activation Syndrome Associated with sJIA Reveals a Potential Role of Type I Interferons in the Expansion of Cycling T Cells

    Kailey Brodeur1, Liang Chen1, zhengping huang2, Yan Du1, Holly Wobma3, Maria Taylor4, Joyce Chang3, Megan Day-Lewis3, Fatma Dedeoglu3, Olha Halyabar3, Mindy Lo3, Jane W. Newburger5, Mary Beth F. Son3, Robert Sundel3, Peter Nigrovic3, lauren henderson3 and Pui Lee3, 1Boston Children's Hospital, Boston, MA, 2Guangdong Second Provincial Hospital, Guangzhou, China, 3Division of Immunology, Boston Children's Hospital, Boston, MA, 4Division of Immunology, Boston Children's Hospital, Brighton, MA, 5Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Macrophage activation syndrome (MAS) is a complication of systemic juvenile idiopathic arthritis (sJIA) characterized by cytokine storm and overt immune cell activation. We aim…
  • Abstract Number: 0856 • ACR Convergence 2022

    A Cross-Sectional Description of Physical Activity (PA) in Children with Juvenile Idiopathic Arthritis (JIA): The LEAP Study (Linking Exercise, Activity, and Pathophysiology in Canadian Children with Arthritis)

    Lori Tucker1, Jaime Guzman2, Lamia Hayawi3, Nick Barrowman3, Heather Macdonald4, Kristin Houghton5, David Cabral6, Bianca Lang7, Dax Rumsey8, Elizabeth Stringer9, Shirley Tse10, Roberta Berard11, Claire Leblanc12, Tommy Gerschman13, Liane Heale14, Karen Watanabe-Duffy15, Sarah Campillo12, Natalie Shiff16 and Ciaran Duffy17, 1British Columbia Children's Hospital, Vancouver, BC, Canada, 2University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada, 3Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada, 4University of British Columbia, Vancouver, BC, Canada, 5University of British Columbia - Vancouver, Vancouver, BC, Canada, 6BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 7Dalhousie University - Halifax, Halifax, NS, Canada, 8Stollery Children's Hospital, Edmonton, AB, Canada, 9IWK Hospital, Halifax, NS, Canada, 10Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 11London Health Sciences Centre, London, ON, Canada, 12McGill University, Montréal, QC, Canada, 13University of British Columbia - Vancouver, North Vancouver, BC, Canada, 14McMaster University, Oakville, ON, Canada, 15Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, 16Janssen Scientific Affairs, LLC, Horsham, PA, USA/ Department of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada, Philadelphia, PA, 17University of Ottawa, Ottawa, ON, Canada

    Background/Purpose: Participation in physical activity (PA) is a concern of children with JIA , however, factors associated with PA in these children are incompletely understood. …
  • Abstract Number: 0878 • ACR Convergence 2022

    A United States Nationwide Analysis of Total Knee Arthroplasty in Patients < 21 Years Old

    John Gibbons1, Cynthia A. Kahlenberg1, Deanna Jannat-Khah, DrPH, MSPH1, Alexander B. Christ2, Susan Goodman1, Peter Sculco1, Mark Figgie1 and Bella Mehta3, 1Hospital for Special Surgery, New York, NY, 2Keck School of Medicine of USC, Los Angeles, CA, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: Total knee arthroplasty (TKA) is rarely performed in patients under 21 years old and may be performed in this population due to conditions such…
  • Abstract Number: PP08 • ACR Convergence 2022

    Learning to Advocate for Myself and the Young Adult Community While Finding My Place as a Patient Partner at CARRA (Childhood Arthritis and Rheumatology Research Alliance)

    Ela Chintagunta1, Courtney Wells2 and Kristine Carandang3, 1Young Patients' Autoimmune Research & Empowerment Alliance, Chicago, IL, 2University of Wisconsin-River Falls; Young Patients' Autoimmune Research and Empowerment Alliance, St. Paul, MN, 3Young Patients' Autoimmune Research & Empowerment Alliance, San Diego, CA

    Background/Purpose: I was diagnosed with Juvenile Idiopathic Arthritis at the age of 13 when I was experiencing joint swelling in my lower body and my…
  • Abstract Number: 0858 • ACR Convergence 2022

    Predicting the Occurrence of Drug-Free Inactive Disease Two Years After Diagnosis of Non-Systemic Juvenile Idiopathic Arthritis

    Melissa Mannion1, Chen Chen2, Olha Halyabar3, Susan Paetkau4, Tingting Qiu5 and Bin Huang6, 1University of Alabama at Birmingham, Birmingham, AL, 2Cincinnati Children's Hospital Medical Center, Taipei, Taiwan, 3Children's Hospital/Boston Medical Center, Boston, MA, 4The Hospital for Sick Children, Toronto, ON, Canada, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Cincinnati Children's Hospital Medical Center, Cinciannati, OH

    Background/Purpose: The goal of treatment for juvenile idiopathic arthritis (JIA) is inactive disease (ID), but the optimal treatment for each patient to maximize ID and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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