ACR Meeting Abstracts

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Abstracts tagged "juvenile idiopathic arthritis (JIA) and pediatric rheumatology"

  • Abstract Number: 2390 • 2018 ACR/ARHP Annual Meeting

    Incidence of and Risk Factors for Adrenal Suppression Following Ultrasound-Guided Intra-Articular Corticosteroid Injection with Triamcinolone Acetonide in Juvenile Idiopathic Arthritis

    Katherine K Ngo1, Angelina Bernier1, Melissa E Elder2, Renee F Modica2 and Akaluck Thatayatikom1, 1Pediatrics, University of Florida, Gainesville, FL, 2Department of Pediatrics, University of Florida, Gainesville, FL

    Background/Purpose: Intra-articular corticosteroid injection (IACI) is routinely used in juvenile idiopathic arthritis (JIA) with oligoarticular disease and as adjunct therapy for other types of JIA.…
  • Abstract Number: 2397 • 2018 ACR/ARHP Annual Meeting

    The Impact of Adalimumab on Growth in Patients with Pediatric Enthesitis-Related Arthritis

    Rubén Burgos-Vargas1, Shirley M.L. Tse2, Kirsten Minden3, Pierre Quartier4, Jaclyn K. Anderson5, Kristina Unnebrink6, Ivan Lagunes Galindo5 and Gerd Horneff7, 1Hospital General de Mexico, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, 2The Hospital for Sick Children, Toronto, ON, Canada, 3Charite University Medicine, Berlin, Germany, 4Hopital Necker-Enfants Malades, Paris, France, 5AbbVie Inc., North Chicago, IL, 6AbbVie Deutschland GmbH & Co., Ludwigshafen, Germany, 7Asklepios Clinic Sankt Augustin, and University Hospital of Cologne, Cologne, Germany

    Background/Purpose: Children with one or more subtypes of juvenile idiopathic arthritis, such as enthesitis-related arthritis (ERA), often exhibit growth impairments. The purpose of the analysis…
  • Abstract Number: 2032 • 2018 ACR/ARHP Annual Meeting

    Effector T Helper Cell Differentiation and Cytokine Secretion Are Increased in Young Children with Juvenile Idiopathic Arthritis

    Anna Patrick1, Thomas Aune2, Jessica Duis3 and T. Brent Graham4, 1Pediatric Rheumatology, Monroe Carell Junior Children's Hospital at Vanderbilt, Division of Pediatric Rheumatology, Nashville, TN, 2Medicine, Vanderbilt University Medical Center, Division of Rheumatology, Nashville, TN, 3Pediatrics, Monroe Carell Junior Children's Hospital at Vanderbilt, Division of Medical Genetics and Genomic Medicine, Nashville, TN, 4Pediatrics, Monroe Carell Junior Children's Hospital at Vanderbilt, Division of Pediatric Rheumatology, Nashville, TN

    Background/Purpose: T cells play a critical role in the body’s response to pathogens. A naïve T helper (Th0) cell proliferates in response to antigen encounter…
  • Abstract Number: 9 • 2017 Pediatric Rheumatology Symposium

    Biologically-Based Approach for Classifying Chronic Childhood Arthritis

    Elham Rezaei1, Daniel Hogan2, Brett Trost2, Anthony Kusalik2, Susanne Benseler3, Gilles Boire4, David A. Cabral5, Bonnie Cameron6, Sarah Campillo7, Gaëlle Chédeville8, Paul Dancey9, Ciarán M. Duffy10, Karen N Watanabe Duffy11, Janet Ellsworth12, Simon Eng13, Brian M. Feldman14, John Gordon2, Jaime Guzman15, Kristin Houghton16, Adam Huber17, Quaid Morris13, Bianca Lang18, Deborah M. Levy19, Loren Matheson20, Kiem Oen21, Ross Petty22, Suzanne Ramsey23, Johannes Roth24, Dax Rumsey25, Claire Saint-Cyr26, Rayfel Schneider27, Rosie Scuccimarri28, Earl Silverman19, Lynn R. Spiegel29, Elizabeth Stringer18, Shirley M.L. Tse30, Lori Tucker31, Rae S.M. Yeung32 and Alan Rosenberg1, 1Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 2University of Saskatchewan, Saskatoon, SK, Canada, 3Pediatric Rheumatology, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada, 4Rheumatology Division, CHUS - Sherbrooke University, Sherbrooke, QC, Canada, 5Pediatrics/Rm K4-121, BC Children's Hospital, Vancouver, BC, Canada, 6The Hospital for Sick Children, Toronto, ON, Canada, 7Montreal Children's Hospital, Montreal, QC, Canada, 8Rheumatology, McGill University, Montreal, QC, Canada, 9Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, 10Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, 11Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, 12University of Alberta, Edmonton, AB, Canada, 13University of Toronto, Toronto, ON, Canada, 14Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 15Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, 16Rheumatology/Pediatrics, British Columbia Childrens Hos, Vancouver, BC, Canada, 17IWK Health Centre, Halifax, NS, Canada, 18Dalhousie University, Halifax, NS, Canada, 19Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 20University of Saskatchewan, Ottawa, ON, Canada, 21University of Manitoba, Winnipeg, MB, Canada, 22Pediatric Rheumatology, Division of Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, 23Pediatric Rheumatology, IWK Health Centre, Halifax, NS, Canada, 24Pediatric Rheumatology, Children's Hospital Eastern On, Ottawa, ON, Canada, 25Stollery Children's Hospital, Edmonton, AB, Canada, 26Pediatrics, CHU Sainte-Justine, Montreal, QC, Canada, 27Division of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 28Division of Pediatric Rheumatology, Montreal Children's Hospital/McGill University Health Centre, Montreal, QC, Canada, 29Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, 30Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 31Pediatric Rheum/Rm K4-120, BC Childrens Hospital, Vancouver, BC, Canada, 32Paediatrics, Immunology and Medical Science, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) comprises a heterogeneous group of conditions that share chronic arthritis as a common characteristic. International uniformity in classifying JIA, based…
  • Abstract Number: 116 • 2017 Pediatric Rheumatology Symposium

    Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study

    Kathryn Phillippi1, Thomas Sferra2, Nora Singer3 and Elizabeth Brooks4, 1Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children’s Hospital / Case Medical Center, Cleveland, OH, 2Pediatric Gastroenterology, Rainbow Babies and Children's Hospital/Case Medical Center, Cleveland, OH, 3MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, Cleveland, OH, 4Division of Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children’s Hospital / Case Medical Center, Cleveland, OH, Cleveland, OH

    Background/Purpose: Inflammatory bowel disease (IBD) is associated with extra-intestinal manifestations, the most common of which is arthralgia/arthritis. 4.1- 15% of patients with inflammatory bowel disease…
  • Abstract Number: 393 • 2016 ACR/ARHP Annual Meeting

    Association of Sex, Race and Ethnicity on Disease Outcomes in Juvenile Idiopathic Arthritis Patients

    Vivek Joseph1, Tracy R. Andrews2, Esi Morgan3, Ronald Laxer4, cagri Toruner5, Tzielan Lee6,7, Beth S. Gottlieb8, C. April Bingham9, Sheetal S. Vora10, Jon M. Burnham11, Judyann C. Olson12, Murray H. Passo13, Michelle Batthish14, Meredith Riebschleger15 and Jennifer E. Weiss16, 1Internal Medicine, Rutgers New Jersey Medical School, Bloomfield, NJ, 2Biostatistics, David & Alice Jurist Institute, Hackensack University Medical Center, hackensack, NJ, 3Pediatric Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, 4Div of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 5Rheumatology, Nationwide Children's Hospital, Columbus, OH, 6Dept of Pediatric Rheumatology, Stanford Univ School of Med, Palo Alto, CA, 7Pediatric Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 8Pediatric Rheumatology, The Steven and Alexandra Cohen Children's Medical Center of New York, The Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY, 9Penn State Health Children's Hospital, Hershey, PA, 10Pediatric Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 11Pediatric Rheumatology, Children's Hospital Philadelphia, Philadelphia, PA, 12Ped/MACC Fund Research Ctr, Medical College of Wisconsin, Milwaukee, WI, 13Division of Rheumatology PTD, Medical University of South Carolina, Charleston, SC, 14Division of Pediatric Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, 15Pediatric Rheumatology, University of Michigan, CS Mott Children's Hospiatl, Ann Arbor, MI, 16Hackensack Univ Med Ctr, Hackensack, NJ

    Background/Purpose: JIA patients are predominantly non-Hispanic white and studies have shown that race and ethnicity may be associated with worse disease.  This study assesses the…
  • Abstract Number: 1355 • 2016 ACR/ARHP Annual Meeting

    ASAH1 Gene Mutations Cause Acid Ceramidase Deficiency (Farber Disease), with Symptoms Including Arthritis and Subcutaneous Nodules. Patients Are Often Misdiagnosed with JIA, and Slowly Progressive Disease May Only be Diagnosed in Adulthood

    Alexander Solyom1, Calogera Simonaro2 and Edward Schuchman3, 1Roivant Sciences, New York, NY, 2Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 3Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: Mutations in the ASAH1 gene cause acid ceramidase deficiency, accumulation of the pro-inflammatory and pro-apoptotic lipid ceramide, and a distinct set of clinical features,…
  • Abstract Number: 933 • 2014 ACR/ARHP Annual Meeting

    A Multi-Center, Double-Blind, Randomized-Withdrawal Trial of Subcutaneous Golimumab in Pediatric Patients with Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy: Week 48 Results

    Hermine I. Brunner1, Nicolino Ruperto2, N Tzaribachev3, Gerd Horneff4, Carine Wouters5, Violeta Vladislava Panaviene6, Vyacheslav Chasnyk7, Carlos Abud-Mendoza8, Ruben Cuttica9, Andreas Reiff10, M Maldonado-Velázquez1, Nadina Rubio-Pérez11, Rik Joos12, V Keltsev13, Evgeny Nasonov14, Daniel Kingsbury15, M Bandeira16, Earl Silverman17, F Weller-Heinemann11, A van Royen-Kerkhof18, Alan M. Mendelsohn19, Lilianne Kim20, Daniel Lovell21 and A Martini22, 1PRCSG, Cincinnati, OH, 2Pediatria II,, Istituto Giannina Gaslini, Genoa, Italy, 3PRINTO & PRCSG, Bramstedt, Germany, 4Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 5Pediatric Rheumatology, University Hosp Gasthuisberg, Leuven, Belgium, 6Istituto Giannina Gaslini, Genoa, Italy, 7Litovskaya Str., 2, Novartis Pharma, Saint-Peterburg, Russia, 8Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 9Tilcara 3023, Hospital de Ninos Pedro de Elizalde, Capital Federal, Argentina, 10Children’s Hospital of Los Angeles, Los Angeles, CA, 11PRINTO, Genoa, Italy, 12UZ Gent, Gent, Belgium, 13Paediatric Rheumatology International Trials Organisation–IRCCS [PRINTO], Genoa, Italy, 14State Institute of Rheumatology of RAMS, Moscow, Russia, 15Pediatric Rheumatology, Randall Children's Hospital at Legacy Emanuel, Portland, OR, 16Pediatrics, Hospital Infantil Pequeno Príncipe, Curitiba, Brazil, 17Division of Rheumatology, Hosp for Sick Children, Toronto, ON, Canada, 18Department of Pediatric Immunology & Rheumatology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, Netherlands, 19Immunology, Janssen Research & Development, LLC., Spring House, PA, 20Janssen Research & Development, LLC., Spring House, PA, 21Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, 22Istituto Gaslini-PRINTO, Genova, Italy

    Background/Purpose:   To assess efficacy and safety of SC golimumab (GLM) in polyarticular pediatric juvenile idiopathic arthritis pts (aged 2 to
  • Abstract Number: 281 • 2014 ACR/ARHP Annual Meeting

    Retrospective Review of Immobilization Vs. Immediate Resumption of Activity in Patients with Oligoarticular Juvenile Idiopathic Arthritis and Corticosteroid Knee Injections

    Elaine Ramsay1, Heather Benham2, Jenna Tress3, Janille Diaz4 and David D. Sherry3, 1Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Pediatric Rheumatology, Texas Scottish Rite Hospital for Children, Dallas, TX, 3Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia,, PA

    Background/Purpose Intraarticular corticosteroid injection (IACI) is one of the most common treatment modalities in oligoarticular Juvenile Idiopathic Arthritis (JIA). There is widespread use of IACI…
  • Abstract Number: 292 • 2014 ACR/ARHP Annual Meeting

    Flares in Children with JIA: Results from the Reacch-out Cohort

    Lori B. Tucker1, Jaime Guzman1, Kiem Oen2 and ReACCh Out Investigators3, 1Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 2Pediatrics, Children's Hospital of Winnipeg and University of Manitoba, Winnipeg, MB, Canada, 3BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose:   Disease flares are a concern to patients with JIA, their parents, and caregivers alike; but little is known of disease manifestations during a…
  • Abstract Number: 270 • 2014 ACR/ARHP Annual Meeting

    Disease Burden Is Comparable in Children with Enthesitis-Related Arthritis and Polyarticular Juvenile Idiopathic Arthritis

    Pierre Quartier1, Jasmina Kalabic2, Zbigniew Zuber3, Kirsten Minden4 and Jaclyn K. Anderson5, 1Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 2AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, 3St. Louis Children’s Hospital, Krakow, Poland, 4Charité Universitätsmedizin Berlin, Berlin, Germany, 5AbbVie Inc., North Chicago, IL

    Background/Purpose: To compare baseline disease characteristics of pediatric patients (pts) with enthesitis-related arthritis (ERA) and polyarticular juvenile idiopathic arthritis (pJIA) from clinical trials with adalimumab…
  • Abstract Number: 2865 • 2013 ACR/ARHP Annual Meeting

    Gene Expression Profiles Of Fibroblast-Like Synoviocytes In Early Stage Of Oligoarticular Juvenile Idiopathic Arthritis Are Different In Extended Versus Persistent Course

    AnneMarie C. Brescia1, Megan M. Simonds2, Suzanne M. McCahan2, Paul T. Fawcett2 and Carlos D. Rose1, 1Pediatric Rheumatology, Thomas Jefferson University/ AI duPont Hospital for Children, Wilmington, DE, 2Nemours Research, Nemours/AI duPont Hospital for Children, Wilmington, DE

    Background/Purpose: Our goal is the identification of informative synovial biomarkers to predict persistent vs extended course in oligoarticular JIA patients. Methods: Stored remnant synovial fluid…
  • Abstract Number: 1150 • 2012 ACR/ARHP Annual Meeting

    Adverse Events in Juvenile Idiopathic Arthritis: Results From the Enhanced Drug Safety Surveillance (EDSS) Pilot Project

    Sarah Ringold1, Audrey F. Hendrickson2, Carol A. Wallace3 and Rachel E. Sobel4, 1Pediatrics, Seattle Children's Hospital/Univ of Washington, Seattle, WA, 2Rheumatology, Seattle Children's Research Institute, Seattle, WA, 3Pediatrics, Seattle Childrens Hospital, Seattle, WA, 4Epidemiology, Worldwide Safety Strategy, Pfizer, Inc., New York, NY

    Background/Purpose: There are few data available regarding the rates of serious and important medical events (SAEs and IMEs) for most of the medications used to…
  • Abstract Number: 862 • 2012 ACR/ARHP Annual Meeting

    What Is the Impact of a Transition Program On Adolescents with Juvenile Idiopathic Arthritis and Their Parents ?

    Deborah Hilderson1, Rene Westhovens2, Rik Joos3, Carine H. Wouters4 and Philip Moons5, 1Department of Paediatrics; Centre for Health Services and Nursing Research, University Hospital Leuven, KU Leuven, Leuven, Belgium, 2Rheumatology Department of development and regeneration, University Hospital KU Leuven, Leuven, Belgium, 3PRINTO, Genoa, Italy, 4Pediatric Rheumatology, University Hospital KU Leuven, Leuven, Belgium, 5Centre for Health Services and Nursing Research, KU Leuven, Leuven, Belgium

    Background/Purpose: To date, there is no structured or systematic approach in Belgium for transferring adolescents with juvenile idiopathic arthritis from pediatric rheumatology to an adult…
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