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Abstracts tagged "Joint destruction and rheumatoid arthritis (RA)"

  • Abstract Number: 2574 • ACR/ARHP Annual Meeting 2016

    IL-22 As a Biomarker for Erosive Disease in Rheumatoid Arthritis

    Jan Leipe, Hendrik Schulze-Koops and Alla Skapenko, Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany

    Background/Purpose: Consistent with models of experimental arthritis implicating IL-22 – in the development of joint destruction could previously demonstrate that elevated IL-22 serum levels were…
  • Abstract Number: 1532 • ACR/ARHP Annual Meeting 2015

    Occurrence of Valvular Heart Disease in Rheumatoid Arthritis: A Population Based Study

    Tamanna Khullar1, John P. Bois1, Cynthia S. Crowson2, Megan L. Krause3 and Rekha Mankad1, 1Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: Patients with rheumatoid arthritis (RA) are known to have an increased risk of cardiovascular disease, particularly atherosclerosis and heart failure.  However, little is known…
  • Abstract Number: 1557 • ACR/ARHP Annual Meeting 2015

    The Impact of Hindfoot Deformity on Disability of Korean Patients with Rheumatoid Arthritis

    Hye-Jin Jeong1, Il Woong Sohn1, Seung Lee1, Seung Taek Song1, Soo-Kyung Cho2 and Yoon-Kyoung Sung2, 1Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose: Rheumatoid arthritis (RA) commonly involves the hindfoot, but this part is frequently overlooked when caring for patients with multiple joints pain and deformity. For…
  • Abstract Number: 1630 • ACR/ARHP Annual Meeting 2015

    Progressive Destruction of Large Joints in Patients with Rheumatoid Arthritis Treated with Biologic Agents

    Arata Nakajima1, Masato Sonobe2 and Koichi Nakagawa2, 1Orthopaedics, Toho University Sakura Medical Center, Sakura, Japan, 2Toho University Sakura Medical Center, Sakura, Japan

    Background/Purpose: Many clinical trials have revealed that biologic agents inhibit destruction of small joints, however, there have been a few reports demonstrating their inhibitory effects…
  • Abstract Number: 1841 • ACR/ARHP Annual Meeting 2014

    Eventual Joint Failure and Surgery Rates in Rheumatoid Arthritis Remain High in Patients with Moderate Disease Activity in the First 5 Years of Disease

    Elena Nikiphorou1, Lewis Carpenter2, Sam Norton3, Josh Dixey4, Patrick Kiely5, David Walsh6,7 and Adam Young1,8, 1School of Life & Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom, 2Centre for Lifespan & Chronic Illness Research, University of Hertfordshire, Hatfield, United Kingdom, 3Institute of Psychiatry, King's College London, London, United Kingdom, 4Rheumatology, New Cross Hospital, Wolverhampton, United Kingdom, 5Rheumatology Dept, St. Georges Healthcare NHS Trust, London, United Kingdom, 6Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom, 7Rheumatology, Sherwood Forest Hospitals NHS Foundation Trust, Sutton-in-Ashfield, United Kingdom, 8Rheumatology, ERAS, St Albans City Hospital, St Albans, United Kingdom

    Background/Purpose: It is well-established that sustained high disease activity in RA results in worse outcomes. In reality many patients remain in low/moderate disease activity states,…
  • Abstract Number: 90 • ACR/ARHP Annual Meeting 2014

    Genetic Variants in IL-6, IL-10, C5-TRAF1 and FCRL3 and Progression of Joint Damage in Rheumatoid Arthritis; A Study on Six Cohorts

    H.W. van Steenbergen1, L. Rodriguez-Rodriguez2, E. Berglin3, A. Zhernakova4, R. Knevel1, J. Ivorra-Cortes5, T.W.J. Huizinga1, B. Fernández-Gutiérrez6, P.K. Gregersen7, S. Rantapää-Dahlqvist8 and A.H.M. van der Helm-van Mil1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 3Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, 4Genetics, University Medical Center Groningen, Groningen, Netherlands, 5Rheumatology, University Hospital la Fe, Valencia, Spain, 6Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 7The Feinstein Institute for Medical Research, Manhasset, NY, 8Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden

    Background/Purpose Understanding the mechanisms underlying the inter-individual differences in radiographic progression is relevant and heritability studies have shown that genetic factors explain part of these…
  • Abstract Number: 2259 • ACR/ARHP Annual Meeting 2013

    Does a Ratingen Score Of ≥ 3 At Disease Onset Define RA In ACR/EULAR 2010 Criteria Negative Patients?

    Ruediger Mueller1, Toni Kaegi1, Sarah Haile2 and Johannes von Kempis1, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Clinical Trials Unit, Kantonsspital St. Gallen, St. Gallen, Switzerland

    Background/Purpose: A EULAR task force has recently selected an evidence and consensus based definition of erosive disease defining rheumatoid arthritis (RA) in patients who do…
  • Abstract Number: 2660 • ACR/ARHP Annual Meeting 2012

    Progressive Radiographic Joint Damage in Established Rheumatoid Arthritis: Common and Strongly Associated with Seropositivity

    Siri Lillegraven1, Nancy A. Shadick2, Zarif Jabbar-Lopez3, Anna Potapov3, Michelle A. Frits4, Christine K. Iannaccone4, Espen A. Haavardsholm1, Tore K. Kvien5, Michael Weinblatt2 and Daniel H. Solomon6, 1Diakonhjemmet Hospital, Oslo, Norway, 2Brigham and Women's Hospital, Boston, MA, 3Harvard School of Public Health, Boston, MA, 4Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Division of Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: During the last decade, rheumatoid arthritis (RA) research has mainly focused on early disease, as it has become apparent that early and aggressive treatment…
  • Abstract Number: 1009 • ACR/ARHP Annual Meeting 2012

    A New Approach for Detecting Progressive Joint Damage Using 3D Imaging From High-Resolution Peripheral Quantitative Computed Tomography: Measuring Reproducibility

    Cheryl Barnabe1, Helen R. Buie2, Michelle Kan2, Susan G. Barr3, Liam Martin3 and Steven K. Boyd2, 1Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, 2Mechanical Engineering, University of Calgary, Calgary, AB, Canada, 3Medicine, University of Calgary, Calgary, AB, Canada

    A New Approach for Detecting Progressive Joint Damage using 3D Imaging from High-Resolution Peripheral Quantitative Computed Tomography: Measuring Reproducibility Background/Purpose: Joint space narrowing is an…

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