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Abstracts tagged "Intervention"

  • Abstract Number: 1965 • ACR Convergence 2025

    Two-Year Outcomes of Microwave Ablation for Recurrent Monoarthritis with Synovial Hypertrophy Resistant to Medical Treatment: Expanded Cohort and Long-Term Follow-Up Results

    Rabia Deniz1, Tevfik Güzelbey2, İlhan Nahit Mutlu2, Kübra Kalkan3, Özgür Kılıçkesmez2 and Cemal Bes4, 1University of Health Sciences Basaksehir Çam and Sakura City Hospital, Istanbul, Turkey, 2University of Health Sciences Başakşehir Çam and Sakura City Hospital, Department of Radiology, Istanbul, Turkey, 3University of Health Sciences Başakşehir Çam and Sakura City Hospital, Department of Rheumatology, Istanbul, Turkey, 4University of Health Sciences, Basaksehir Çam and Sakura City Hospital, Istanbul, Turkey

    Background/Purpose: Recurrent monoarthritis (RM) is a significant therapeutic challenge in rheumatology, often persisting despite NSAIDs, corticosteroids (CS), DMARDs, and biologic therapies. Local interventions like intra-articular…
  • Abstract Number: 1832 • ACR Convergence 2025

    Time-to-Event Analysis of Statin Use and Thrombotic Risk in Patients with Systemic Lupus Erythematosus: A Single-Center Retrospective Study

    Christine Lenchur1, Niurka Liranzo Tejera1, Adal Abonamah1, Takemichi Matsui1, Emily Cosentino1, Priscilla Abate Namnum2, Olga Marushchak1, Melissa Akselrad1, Martin John3, Sophia Lutgen4, Celestine He5, Boluwatito Oladeinde3, Harleen Sidhu6, Emilia Bagiella5, Ian Wright5 and Chrisanna Dobrowolski5, 1Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY, 2Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York, 3Icahn School of Medicine at Mount Sinai, New York, 4Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York City, NY, 5Icahn School of Medicine at Mount Sinai, New York, NY, 6Icahn School of Medicine at Mount Sinai/NYC H+H- Elmhurst, Queens, NY, Rego Park, NY

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) face elevated risk of thrombotic events (TEs) due to traditional cardiovascular factors and chronic inflammation. Statins may offer…
  • Abstract Number: 1586 • ACR Convergence 2025

    Real-World Safety and Efficacy of JAK Inhibitors in Systemic Sclerosis: A Propensity-Matched EUSTAR Study

    Stefano Di Donato1, Marie-Elise Truchetet2, Marco Minerba3, Oliver Distler4, JUAN JOSE ALEGRE SANCHO5, Yolanda Braun Moscovici6, Christina Bergmann7, Petros Sfikakis8, Jeska de Vries-Bouwstra9, Murray Baron10, Silvia Bellando-Randone11, Lorenzo Dagna12, Christopher Denton13, Madelon Vonk14, Vanessa Smith15, Ivan Castellvi16, Gabriela Riemekasten17, Andra Balanescu18, Masataka Kuwana19, Maria De Santis20, Kamal Solanki21, Anastas Batalov22, Vahan Mukuchyan23, Marco Matucci-Cerinic24, Yannick Allanore25, Francesco Del Galdo26 and Michael Hughes27, 1University of Leeds, Canosa Sannita, Chieti, Italy, 2Bordeaux University Hospital, Bordeaux, France, 3Campus Bio-Medico University of Rome, Taranto, Taranto, Italy, 4Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland, Zurich, Switzerland, 5Department of rheumatology. Hospital Universitario Doctor Peset, Valencia, Spain, 6Rambam Heath Care Campus, Haifa, Israel, 7Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, 8NKUA - SCHOOL OF MEDICINE, Athens, Greece, 9Leiden University Medical Center, Leiden, Netherlands, 10Self employed, Montréal, Canada, 11University of Florence, Florence, Florence, Italy, 12Ospedale San Raffaele, Milano, Italy, 13University College London, UK, London, United Kingdom, 14Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 15Ghent University Hospital, Gent, Belgium, 16Hospital Universitari de la Santa Creu i Sant Pau, Sant Just Desvern, Spain, 17University Clinic Schleswit-Holstein (UKSH), Lübeck, Germany, 18UNIVERSITY OF MEDICINE AND PHARMACY CAROL DAVILA, Bucharest, Romania, 19Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 20Humanitas University, Pieve Emanuele, Italy, 21Waikato Hospital, Hamilton, New Zealand, 22Medical University of Plovdiv, Plovdiv, Bulgaria, 23"Erebuni" Medical Center, Yerevan, Armenia, 24University San Raffaele Milano, Milano, Milan, Italy, 25Université Paris Cité, Paris, France, 26University of Leeds, Leeds, United Kingdom, 27Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK, Manchester, England, United Kingdom

    Background/Purpose: Systemic sclerosis (SSc) is a complex systemic autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. While JAK inhibitors (JAKi) have shown promising immunomodulatory…
  • Abstract Number: 1587 • ACR Convergence 2025

    Longitudinal Clinical Response to JAK Inhibitors in Systemic Sclerosis: A Real-Life Multicentric Study Across Clinical Domains

    Stefano Di Donato1, JUAN JOSE ALEGRE SANCHO2, Anastas Batalov3, Zguro Batalov4, Silvia Bellando-Randone5, carmela coccia6, Marco de Pinto7, Dilia Giuggioli8 and Michael Hughes9, 1University of Leeds, Canosa Sannita, Chieti, Italy, 2Department of rheumatology. Hospital Universitario Doctor Peset, Valencia, Spain, 3Medical University of Plovdiv, Plovdiv, Bulgaria, 4UMHAT Kaspela, Ploudiv, Bulgaria, 5University of Florence, Florence, Florence, Italy, 6Rheumatology Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy, 7Azienda Ospedaliero Universitaria Policlinico di Modena, Parma, Parma, Italy, 8Scleroderma Unit, Rheumatology Unit, University Hospital of Modena and Reggio Emilia, Modena, Italy, Modena, Italy, 9Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK, Manchester, England, United Kingdom

    Background/Purpose: JAK inhibitors (JAKi) have shown promising early results in systemic sclerosis (SSc) patients, yet real-world data on their longitudinal effects across different disease domains…
  • Abstract Number: 1246 • ACR Convergence 2025

    Myo Vs. Myo-fascial Injection for Myofascial Trigger Points. Is There Really a Difference? A Randomized Controlled Trial

    seda yildiz1, bugra ince1 and Halil ibrahim candal2, 1izmir sehir hastanesi, izmir, Turkey, 2ızmir sehir hastanesi, izmir

    Background/Purpose: Experimental and clinical studies suggest that fascial structures play a critical role in the pathogenesis and pain mechanisms of myofascial pain syndrome (MTrP). It…
  • Abstract Number: 1190 • ACR Convergence 2025

    IgG4-related disease with comorbid autoimmune diseases: a retrospective study from a large cohort

    Xinli Yang1, Wen Zhang2, Jiaxin zhou3 and Yuxue Nie4, 1Peking Union Medical College, Dong Cheng Qu, China (People's Republic), 2Peking Union Medical College Hospital, Dong Cheng Qu, China (People's Republic), 3Peking Union Medical College Hospital, Beijing, China (People's Republic), 4Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, Dong Cheng Qu, China (People's Republic)

    Background/Purpose: This study aimed to explore the clinical characteristics, treatment, and prognosis of IgG4-related disease (IgG4-RD) patients with comorbid autoimmune diseases (AIDs).Methods: A total of…
  • Abstract Number: 1182 • ACR Convergence 2025

    Cardiac Sarcoidosis in Black Patients: A Biopsy-Confirmed Cohort Study

    Roshan Subedi1, Haya Haddad2, Rachel Barish1, Tania Vora1, Nana Afari-Armah3, Ajay Kadakkal1, Farooq Sheikh1 and Florina Constantinescu1, 1Medstar Washington Hospital Center, Washington, DC, 2Medstar Washington Hospital Center, Silver Spring, MD, 3Medstar Washington Hospital Center, Washington

    Background/Purpose: Sarcoidosis is an inflammatory disease characterized by non-necrotizing granulomatous inflammation that can affect any organ. Approximately 5% of patients with sarcoidosis develop clinically significant…
  • Abstract Number: 0974 • ACR Convergence 2025

    Tissue resident macrophages derived from induced pluripotent stem cells induce tissue fibrosis in human skin equivalent models of systemic sclerosis

    Xuezhi Hong1, Yanhua Xiao2, shihao zhu3, Yi-Nan Li4, Linlin Huang3, Martin Regensburger5, Franz Marxreiter6, Tim Filla7, Andrea-Hermina Györfi8, James Adjaye9, Jürgen Winkler6, Florian Groeber-Becker10, Jörg Distler11 and Alexandru-Emil Matei12, 1Department of Rheumatology, University Hospital Dusseldorf, Medical Faculty of Heinrich Heine University, Dusseldorf, Germany, Düsseldorf, Germany, 2Medical Faculty of Heinrich Heine University, Dusseldorf, Germany, 3Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany, 4University Hospital of Düsseldorf, Düsseldorf, Germany, 5Department of Stem Cell Biology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany, 6Department of Molecular Neurology, FAU Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany, 7Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University., Düsseldorf, Germany, 8Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University., Düsseldorf, Germany, 9Institute for Stem Cell Research and Regenerative Medicine, University Hospital Düsseldorf, Moorenstrasse 5, D-40225 Duesseldorf, Germany, Dusseldorf, Germany, 10Department of Ophthalmology, University Hospital Düsseldorf, 40225, Düsseldorf, Germany, Dusseldorf, Germany, 11University Hospital Duesseldorf and HHU, Duesseldorf, Germany, 12Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany, Düsseldorf, Germany

    Background/Purpose: Previous studies showed that monocyte-derived macrophages become pro-fibrotic in systemic sclerosis (SSc) and contribute to fibroblast activation. Macrophages are, however, a heterogeneous population. Macrophages…
  • Abstract Number: 0344 • ACR Convergence 2025

    Inpatient Zoledronic Acid for Glucocorticoid-Induced Osteoporosis Prevention

    Gregory Challener1, Zandra E. Walton1, Christine M. Parsons1, Aakash V. Patel2, Alex Tinianow3, Molly E. Griffin1, Raisa Lomanto Silva3, Avira Som1, Laura J. Yockey4, WuQiang Fan5, Sheila L. Arvikar1 and Marcy Bolster6, 1Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, 2Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Massachusetts General Hospital, Boston, MA, 4MGH, Charlestown, MA, 5Division of Endocrinology, Department of Medicine, Massachusetts General Hospital, Boston, 6Massachusetts General Hospital, Concord, MA

    Background/Purpose: Glucocorticoids are widely used in rheumatology and are associated with increased fracture risk. The 2022 ACR Guideline for the Prevention and Treatment of Glucocorticoid-induced…
  • Abstract Number: 0209 • ACR Convergence 2025

    A Retrospective Safety Analysis based on Platelets in Arthrocentesis and Joint injections in Cancer Patients

    Yuanteng Li1, Cheuk Leung2, Heather Lin2, Angeles Lopez-Olivio3 and Jean Tayar3, 1MD Anderson Cancer Center, Houston, TX, 2MD Anderson Cancer Center, Houston, 3The University of Texas, MD Anderson Cancer Center, Houston, TX

    Background/Purpose: Arthrocentesis and joint injections are commonly performed to diagnose and to treat rheumatic conditions such as crystal-induced arthritis, septic arthritis, and inflammatory arthritis. While…
  • Abstract Number: 2690 • ACR Convergence 2025

    Dietary interventions in Psoriatic Arthritis: A Randomized controlled clinical trial

    Lihi Eder1, Sohan Shahab2, Sarah Hopkins Gillespie3, Laura Bumbulis4, Helen Emanoilidis5, Charlene Compher6, Jose Scher7, Dafna D. Gladman8, Richard Cook4, Vinod Chandran1 and Alexis Ogdie9, 1University of Toronto, Toronto, ON, Canada, 2Women’s College Research Institute, Women’s College Hospital, Toronto, Canada, 3University of Pennsylvania, Philadelphia, PA, 4University of Waterloo, Waterloo, Canada, 5Women’s College Hospital, Toronto, Canada, 6University of Pennsylvania School of Nursing and Hospital of the University of Pennsylvania, Philadelphia, 7New York University School of Medicine, New York, NY, 8Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, 9Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE

    Background/Purpose: The Dietary Interventions in Psoriatic Arthritis (DIPSA) study is a multicentre randomized controlled trial (RCT) designed to evaluate the efficacy of two personalized dietary…
  • Abstract Number: 2687 • ACR Convergence 2025

    Glucagon-like peptide-1 receptor agonists therapy is associated in improvement in psoriatic arthritis-related and metabolic outcomes: A retrospective analysis of two cohorts

    Lihi Eder1, Uma Scher2, Kyra Chen3, Alexandra L. Rice3, Sydney Thib4 and Rebecca Haberman5, 1University of Toronto, Toronto, ON, Canada, 2NYU School of Medicine, Scarsdale, NY, 3NYU Grossman School of Medicine and NYU Langone Health Psoriatic Arthritis Center, New York, 4Women's College Research Institute, Women's College Hospital, Toronto, Canada, 5NYU Langone Health, New York, NY

    Background/Purpose: Obesity is highly prevalent in psoriatic arthritis (PsA) and is associated with reduced therapeutic response, worse disease outcomes, and increased cardiometabolic risk. Glucagon-like peptide-1…
  • Abstract Number: 2524 • ACR Convergence 2025

    Rituximab in the Treatment of Susac Syndrome: Single Center Descriptive Study with a Large Susac Cohort

    Adam Brown1, Leonard Calabrese2 and Rula Hajj-Ali3, 1Cleveland Clinic, Shaker Heights, OH, 2Cleveland Clinic, Cleveland, OH, 3Cleveland Clinic, Cleveland

    Background/Purpose: Susac Syndrome is a rare autoimmune condition causing microvascular occlusions in the brain, retina and inner ear leading to the characteristic triad of encephalopathy,…
  • Abstract Number: 2280 • ACR Convergence 2025

    Changes of B Cell Subsets During Treatment with Abatacept in Patients with Rheumatoid Arthritis

    Athanasios Mavropoulos1, Christos Liaskos2, Ioannis Alexiou3, Christina Katsiari4, Dimitrios Bogdanos5 and Lazaros Sakkas6, 1University of Thessaly, Volos, Greece, 2University of Thessaly, Faculty of Medicine, Larisa, Greece, 3University General Hospital of larissa, Larissa, Greece, 4University General Hospital of Larisa, University of Thessaly Faculty of Medicine, Larisa, Greece, 5Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece, 6Department of Rheumatology, University of Thessaly, Larissa, Greece

    Background/Purpose: Abatacept, an efficacious therapy for rheumatoid arthritis (RA), inhibits the interaction between CD28 on T cells and CD80/CD86 on antigen-presenting cells (APCs). The aim…
  • Abstract Number: 2187 • ACR Convergence 2025

    Transforming MSUS Access in Mexico: A Comparative Study of National Trends and a Hybrid Training Cohort

    Mario R. Garcia-Pompermayer1, SARAH G. AYTON2, Karina Silva Luna3, Ricardo Ramirez-Morales4 and Mario Garza Elizondo5, 1Hospital San Jose Tecnologico de Monterrey, Monterrey, Mexico, 2Columbia University, New York, NY, 3Centro Médico Zambrano Hellion, Monterrey, Mexico, 4Private Rheumatology Practice, Monterrey, Mexico, Monterrey, Nuevo Leon, Mexico, 5Hospital Zambrano-Hellion TecSalud, Monterrey, Mexico

    Background/Purpose: Musculoskeletal ultrasound (MSUS) is a valuable diagnostic tool in rheumatology, yet access to formal MSUS training in Latin America remains limited. In a 2022…
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