Abstracts tagged "Inflammation"

Abstract Number: 1028 • 2012 ACR/ARHP Annual Meeting
Semi-Quantitative Assessment of Bone Marrow Edema and Synovitis-Effusion in Osteoarthritis with the Knee Inflammation MRI Scoring System: A Target Lesion Based Methodology
Walter P. Maksymowych¹, Ulrich Weber², Marcus Pianta³ and Robert GW Lambert³, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ³Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Current MRI scoring methods for assessment of bone marrow lesions (BML) in the knee of patients with osteoarthritis rely on a complex subdivision of…
Abstract Number: 50 • 2012 ACR/ARHP Annual Meeting
Human Chondrocyte Dedifferentiation Is Accompagnied by CD105 Endoglin Expression, ALK-1/Smad1/5 Phosphorylation and Leptin Production – Stimulation by Prednisolone and Aldosterone Through the Glucocorticoid Receptor
Olivier Malaise¹, Biserka Relic², Mustapha Zeddou¹, Edith Charlier¹, Florence Quesada Calvo¹, Sophie Neuville³, Dominique de Seny² and Michel G. Malaise⁴, ¹Department of Rheumatology, GIGA Research - University of Liège - CHU Liège, Liège, Belgium, ²Department of Rheumatology, GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ³GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ⁴Department of Rheumatology, University of Liège - CHU Liège, Liège, Belgium
Background/Purpose: Leptin, mainly produced by the adipose tissue including fat neighboring the joint, is considered as pro-inflammatory in osteoarthritis (OA). Normal cartilage does not…

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