ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Inflammation"

  • Abstract Number: 1361 • 2015 ACR/ARHP Annual Meeting

    Synovial Macrophages Promote TGF-β Signaling but Protect Against Influx of S100A8/S100A9-Producing Cells after Intra-Articular Injections of Oxidized Low-Density Lipoproteins

    Wouter de Munter1, Martijn H. van den Bosch1, Arjen Blom1, Birgitte Walgreen2, Monique Helsen1, Leo Joosten3, Johannes Roth4, Thomas Vogl5, Fons van de Loo1, Marije Koenders1, Wim van den Berg1, Peter van der Kraan1 and Peter van Lent1, 1Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 2Experimentel Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 3Internal Medicine, Radboud university medical center, Nijmegen, Netherlands, 4Institute of Immunology, University of Münster, Münster, Germany, 5University of Muenster, Muenster, Germany

    Background/Purpose:  In previous studies we found that synovial macrophages regulate joint pathology during experimental osteoarthritis (OA). Recently, we found that high systemic levels of LDL…
  • Abstract Number: 2773 • 2015 ACR/ARHP Annual Meeting

    Novel Mechanisms of Action for Methotrexate and Doxycycline: Prevention of Protein Adduct Formation and Free Radical Scavenging

    Daniel Anderson1, Michael J. Duryee2, Matthew Zimmerman3, Jun Tian3, Cleofes Sarmiento3, Lynell W. Klassen4, James R. O'Dell1, Geoffrey M. Thiele5 and Ted R. Mikuls1, 1University of Nebraska Medical Center, Omaha, NE, 2Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 3Cell Biology and Physiology, University of Nebraska Medical Center, Omaha, NE, 4Dept of Internal Medicine, Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 5Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE

    Background/Purpose:  Oxidative stress and free radical formation play an important pathogenic role in rheumatoid arthritis (RA) and a number of other inflammatory diseases.  Oxidative stress…
  • Abstract Number: 1975 • 2014 ACR/ARHP Annual Meeting

    Profiling 14-3-3η in Human Primary Cell Based BioMAP® Disease Models Reveals a Unique Pro-Inflammatory Phenotypic Signature Consistent with RA-Inflammation Biology

    Alison O'Mahony1, Ellen L. Berg1, Walter P. Maksymowych2, Yuan Gui3 and Anthony Marotta4, 1BioSeek, South San Francisco, CA, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3Augurex Life Sciences Corp., North Vancouver, BC, Canada, 41423 Dempsey Road, Augurex Life Sciences Corp., North Vancouver, BC, Canada

    Background/Purpose 14-3-3 proteins represent a highly conserved seven-member family of ubiquitously expressed intracellular chaperonins that perform a broad range of signaling functions.  The 14-3-3 eta…
  • Abstract Number: 911 • 2014 ACR/ARHP Annual Meeting

    Bioluminescent Imaging of Histidyl-Transfer RNA Synthetase-Induced Myositis Reveals Early-Phase Involvement of NF-Kb-Mediated Inflammation

    Nicholas A. Young1, Lai-Chu Wu1, Michael Bruss2, Wael N. Jarjour3 and Dana P. Ascherman4, 1Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 2Division of Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, 3Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, 4Rheumatology, Miami VAMC, Miami, FL

    Background/Purpose:  The idiopathic inflammatory myopathies represent a group of autoimmune diseases that target muscle as well as extra-muscular organs, leading to significant morbidity and mortality. …
  • Abstract Number: 1978 • 2014 ACR/ARHP Annual Meeting

    Role of Monocytes Subsets in the Pathology of Rheumatoid Arthritis: Involvement in Endothelial Dysfunction and Proinflammatory Profile

    Chary Lopez-Pedrera, Patricia Ruiz-Limon, Carlos Perez-Sanchez, Rosario Carretero, Yolanda Jiménez Gómez, Ángeles Aguirre Zamorano, Jerusalem calvo-Gutierrez, Eduardo Collantes-Estevez, Alejandro Escudero-Contreras and Nuria Barbarroja, Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain

    Background/Purpose Different frequency of monocytes subsets has been reported in rheumatoid arthritis (RA).Human monocytes are divided into three main subpopulations according to expression of the…
  • Abstract Number: 832 • 2014 ACR/ARHP Annual Meeting

    NOD2-Associated Autoinflammatory Disease: The Largest Cohort Study

    Qingping Yao1, Min Shen2, Christine McDonald3, Felicitas Lacbawan4 and Bo Shen5, 1Rheumatic and Immunologic Dis, Cleveland Clinic, Cleveland, OH, 2Rheumatic and Immunologic Disease, Cleveland Clinic, Cleveland, OH, 3Pathobiology, Cleveland Clinic, Cleveland, OH, 4Molecular Genetics Pathology, Cleveland Clinic, Cleveland, OH, 5Gastroenterology, Cleveland Clinic, Cleveland, OH

    Background/Purpose NOD2-associated autoinflammatory disease (NAID) is an emerging systemic inflammatory disease. The aim is to report our extended study of the phenotypic and genotypic features of…
  • Abstract Number: 2933 • 2014 ACR/ARHP Annual Meeting

    Metabolic Syndrome, Adipocytokines and Inflammation in Sjögren’s Syndrome

    Kristopherson Lustosa Augusto1, Eloisa Bonfá2, Rosa M. R. Pereira1, Cleonice Bueno3, Vilma S. T. Viana4 and Sandra G. Pasoto5, 1Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 2Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, 3Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 4Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil

    Background/Purpose Systemic inflammation has been linked to increased frequency of metabolic syndrome (MetS) in autoimmune diseases. However, there are no studies concerning the frequency of…
  • Abstract Number: 1964 • 2014 ACR/ARHP Annual Meeting

    Changes in Soluble CD18 Reflect Latency in the Immune System and Predict Radiographic Progression in Early Rheumatoid Arthritis

    Tue Wenzel Kragstrup1, Babak Jalilian1, Kresten Krarup Keller2, Kristian Stengaard-Pedersen3, Merete Lund Hetland4, Kim Hørslev-Petersen5, Peter Junker6, Mikkel Østergaard4, Ellen Margrethe Hauge7,8, Malene Hvid1, Thomas Vorup-Jensen1 and Bent Deleuran1,3, 1Department of Biomedicine, Aarhus University, Aarhus, Denmark, 2Aarhus University Hospital, Aarhus, Denmark, 3Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 4Glostrup University Hospital, Glostrup, Denmark, 5Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, 6Odense University Hospital, Odense, Denmark, 7Dept. of Anatomi, Aarhus University, Aarhus, Denmark, 8Rheumatology, Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose In early rheumatoid arthritis (RA), clinical disease characterized by swollen and painful joints is caused by synovitis. However, presence of autoantibodies may precede the…
  • Abstract Number: 735 • 2014 ACR/ARHP Annual Meeting

    Sarcopenia in Systemic Sclerosis: Prevalence and Association with Functional Parameters and Quality of Life

    Elise Siegert1, Kristina Norman2, Emilie Preis3, Alexander Makowka3, Gerd Burmester4 and Gabriela Riemekasten1, 1Rheumatology and Clinical Immunology, Charité – University Hospital, Berlin, Germany, 2Geriatrics Research Group, Charité – University Medicine Berlin, Berlin, Germany, 3Rheumatology and Clinical Immunology, Charité – University Medicine Berlin, Berlin, Germany, 4Charité – University Medicine Berlin, Berlin, Germany

    Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune disease that characterized by endothelial dysfunction, inflammation and fibrosis. It is associated with high mortality and physical impairment.…
  • Abstract Number: 2876 • 2014 ACR/ARHP Annual Meeting

    Interleukin-10 Receptor Blockade during Lcmv Infection Results in Macrophage Activation Syndrome-like Disease in Mice

    Lehn K. Weaver1 and Edward M. Behrens2, 1Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2Pediatric Rheumatology, Childrens Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Macrophage activation syndrome (MAS) is the rheumatic disease-associated member of a group of hyperinflammatory syndromes characterized by uncontrolled cytokine storm manifest as unremitting fevers,…
  • Abstract Number: 1894 • 2014 ACR/ARHP Annual Meeting

    Is It Worth It to Include MRI of the Spine in the ASAS Classification Criteria for Axial Spondyloarthritis?

    Manouk de Hooge1, Jean-Baptiste Pialat2, Antoine Feydy3, Monique Reijnierse1, Pascal Claudepierre4, Alain Saraux5, Maxime Dougados3 and Désirée van der Heijde1, 1Leiden University Medical Center, Leiden, Netherlands, 2Hôpital Edouard Herriot, Lyon, France, 3Descartes University, Cochin Hospital, Paris, France, 4Henri Mondor Teaching Hospital, Creteil, France, 5CHU de la Cavale Blanche, Brest Cedex, France

    Background/Purpose: Spinal MRI lesions suggestive of axial Spondyloarthritis (axSpA) are not included in the ASAS definition of a positive MRI, but do occur in the…
  • Abstract Number: 660 • 2014 ACR/ARHP Annual Meeting

    Microthrombotic Renal Vascular Lesions Are Associated to Increased Renal Inflammatory Infiltration in a Mouse Model of Lupus Nephritis

    María Galindo1, Elena Gonzalo-Gil2, Oscar Toldos3, Carmen García-Herrero2, Alicia Usategui1, Sonia Pérez-Yagüe4, Gabriel Criado5, Domingo F. Barber4 and Jose L. Pablos1, 1Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 2Department of Rheumatology, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 3Servicio de Anatomia Patologica, Hospital 12 de Octubre, Madrid, Spain, 4Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain, 5Grupo de Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain

    Background/Purpose In patients with lupus nephritis (LN), acute renal vascular and atherosclerotic lesions correlate with the degree of inflammation regardless the presence of antiphospholipid antibodies.…
  • Abstract Number: 2889 • 2014 ACR/ARHP Annual Meeting

    The Association Between Changes in Inflammation and High Density Lipoprotein Cholesterol Efflux Capacity in Rheumatoid Arthritis

    K P Liao1, Martin Playford2, Michelle A. Frits3, Christine K. Iannaccone4, Jonathan S. Coblyn1, Michael E. Weinblatt5, Nancy A. Shadick6 and Nehal N. Mehta7, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2National Heart, Blood, and Lung Institute, Bethesda, MD, 3Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, 4Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology & Immunology, Brigham and Women's Hospital, Boston, MA, 6Brigham and Women's Hospital/Harvard University, Cambridge, MA, 7Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: High density lipoprotein (HDL) cholesterol efflux capacity measures the functional ability of HDL to remove cholesterol from atherosclerotic plaque. Low HDL efflux capacity is…
  • Abstract Number: 1823 • 2014 ACR/ARHP Annual Meeting

    Inflammation Is Associated with Erosive Progression in Patients with Hand Osteoarthritis: A Prospective Ultrasonography Study

    Marion C. Kortekaas1,2, Wing Yee Kwok3, Monique Reijnierse4, Theo Stijnen5 and Margreet Kloppenburg6, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Flevoziekenhuis, Almere-Stad, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands, 4Radiology, Leiden University Medical Center, Leiden, Netherlands, 5Medical Statistics, Leiden University Medical Center, Leiden, Netherlands, 6Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose Erosive hand osteoarthritis (OA) is a subset that shows inflammatory features with ultrasound or MRI much more frequent than non-erosive hand OA, and can…
  • Abstract Number: 611 • 2014 ACR/ARHP Annual Meeting

    Autophagy and Unfolded Protein Response: A Fine Balance That Can Influence the Pathogenesis of Ankylosing Spondylitis and Inflammatory Bowel Disease

    Nigil Haroon1, Giuliana Guggino2, Zhenbo Zhang1, Kirby Yee3, Hasan Abdullah4, Ricardo Alessandro5, Stefania Raimondo5, Giovanni Triolo5 and Francesco Ciccia2, 1Toronto Western Research Institute, Toronto, ON, Canada, 2Rheumatology Unit, University of Palermo, Palermo, Italy, 3McMaster University, Hamilton, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5University of Palermo, Palermo, Italy

    Background/Purpose We have shown an increase in the unfolded protein response (UPR) with decreased ERAP1 or ERAP2 function in an in vitrosystem. Similarly UPR has…
  • « Previous Page
  • 1
  • …
  • 48
  • 49
  • 50
  • 51
  • 52
  • …
  • 58
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology