ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Inflammation"

  • Abstract Number: 82 • 2017 ACR/ARHP Annual Meeting

    CKD-506, a Novel Inhibitor of Histone Deacetylase 6 (HDAC6) Has a Therapeutic Potential in Rheumatoid Arthritis and Inflammatory Bowel Disease

    Jieun Shin1, Nina Ha1, Daekwon Bae1, Dong-Hyeon Suh1, Yu Jin Jang2, Sehui Shon3, Ji-yeon Baek1, Jae Hyun Jun1, Yong Jae Lee1, Changsik Lee1, Sei-Hwan Kim1, Hosung Yu1, Young Il Choi1, Keun Ho Ryu1, Soung-Min Lee4, Yeong Wook Song2, Su K Seo4 and Seong Kon Kim1, 1Research Institute of Chong Kun Dang Pharmaceutical Corporation, Yongin, Korea, Republic of (South), 2Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, Republic of (South), 3Department of Molecular Medicine and Biopharmaceutical Sciences, Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, Republic of (South), 4Department of Microbiology and Immunology, Inje University College of Medicine, Busan, Korea, Republic of (South)

    Background/Purpose: Autoimmune disease such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) is a chronic inflammatory disorder, significantly limiting quality of life. Even though…
  • Abstract Number: 1101 • 2017 ACR/ARHP Annual Meeting

    Systematic Physician Assessment Beyond Inflammation in Routine Rheumatology Care Using Visual Analog Scale Scores for Inflammation, Damage, and Distress to Document Patient Status and Support Clinical Decisions: Analysis of Inter-Rater Reliability

    Shakeel M. Jamal1, Theodore Pincus2, Isabel Castrejón2, Jacquelin R. Chua1, Aman Kugasia1, Juan Schmukler1, Stacy Weinberg1 and Joel A. Block3, 1Division of Rheumatology, Rush University Medical Center, Chicago, IL, 2Rheumatology, Rush University Medical Center, Chicago, IL, 3Rush University Medical Center, Chicago, IL

    Background/Purpose: A physician global estimate of patient status (DOCGL) on a 0-10 visual analog scales (VAS) is as effective as any rheumatoid arthritis (RA) Core…
  • Abstract Number: 1928 • 2017 ACR/ARHP Annual Meeting

    Fibroblast-like Synovial Cell Production of ED-a Fibronectin Contributes to Inflammation in Osteoarthritis

    Tue Wenzel Kragstrup1,2,3, Dong Hyun Sohn4, Christin Lepus3, Kazuhiro Onuma5, Qian Wang3, William H. Robinson3 and Jeremy Sokolove3, 1Randers Regional Hospital, Randers, Denmark, 2Department of Biomedicine, Aarhus University, Aarhus, Denmark, 3VA Palo Alto Healthcare System and Stanford University, Palo Alto, CA, 4Microbiology and Immunology, Pusan National University School of Medicine, Yangsan, Korea, Republic of (South), 5VA Palo Alto Healthcare System and Stanford University, Stanford, CA

    Background/Purpose: The pathophysiology of osteoarthritis (OA) involves wear and tear, and a state of low-grade inflammation. Wear and tear leads to tissue degradation followed by…
  • Abstract Number: 33 • 2017 Pediatric Rheumatology Symposium

    An extracellular ionic milieu renders human granulocytic S100A12 into a pro-inflammatory TLR4-binding alarmin

    Christoph Kessel1, Sabrina Fuehner1, Bastian Zimmermann2, Dirk Holzinger1, Helmut Wittkowski1, Claas Hinze1 and Dirk Foell1, 1Department of Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany, 2Biaffin GmbH & Co KG, Kassel, Germany

    Background/Purpose:  Granulocytic S100A12 is a member of the calgranulin-subgroup within the S100 family of calcium-binding proteins. Similar to other S100 proteins S100A12 can bind divalent…
  • Abstract Number: 131 • 2017 Pediatric Rheumatology Symposium

    Balancing JAK/STAT-signaling with tofacitinib may foster anti-inflammatory functions of human monocytes

    Friederike Cordes1, Eva Lenker2, Toni Weinhage2, Georg Varga2 and Dirk Foell3, 1Gastroenterology, Internal Medicine, University of Muenster, Muenster, Germany, 2Department of Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany, 3Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany

    Background/Purpose: Monocytes are bridging natural and acquired immunity. Information about JAK signaling in monocytes is scarce especially in an inflammatory milieu. JAK-inhibition is a promising…
  • Abstract Number: 146 • 2017 Pediatric Rheumatology Symposium

    Age-Related Differences in Neuronal High Mobility Group Box-1 and Resolvin D1 Receptors in Collagen-Induced Arthritis

    Tracy Wilson-Gerwing and Alan Rosenberg, Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada

    Background/Purpose: More thorough understanding of age-related molecular interactions that drive inflammation and inflammatory pain is required to help guide evidenced-based, age appropriate treatment strategies that…
  • Abstract Number: 178 • 2016 ACR/ARHP Annual Meeting

    Alpha-Enolase Promotes Pro-Inflammatory Phenotype of Monocytes-Derived Macrophages

    Pascal Rottenberg1,2, Manuel Fréret1,2, Sébastien Calbo1 and Olivier Vittecoq1,2, 1INSERM U905 & Normandy University, Institute for Research and Innovation in Biomedicine, Rouen, France, 2Rheumatology, Rouen University Hospital, Rouen, France

    Background/Purpose:  Monocytes of healthy donors were cultured with M-CSF (gcultured with ENO1, or control BSA, to investigate its effect on monocytes differentiation and macrophages polarization.…
  • Abstract Number: 1441 • 2016 ACR/ARHP Annual Meeting

    Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Knockout Attenuates Arthritis Progression and Systemic Inflammation in TNF-Tg Arthritis Mouse Models

    Yahui Grace Chiu1, Richard Bell2, Dongge Li3, Edward Schwarz4 and Christopher T. Ritchlin5, 1Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, 2Pathology, University of Rochester, Rochester, NY, 3Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 4Orthopedeatrics, University of Rochester, Rochester, NY, 5Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Tumor necrosis factor-transgenic (TNF-Tg) mice develop systemic inflammatory polyarthritis. DC-STAMP, a multi-pass transmembrane protein, was originally identified from a dendritic cell library and required…
  • Abstract Number: 2288 • 2016 ACR/ARHP Annual Meeting

    Inflammatory Status and Serum Uric Acid Determine High-Density Lipoprotein Cholesterol Levels in a Non-Rheumatic Population

    Mariano Andrés1, María Amparo Quintanilla2, Eliseo Pascual3, Pedro Morillas2 and FAPRES study group, 1Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, 2Servicio de Cardiología, Hospital General Universitario de Elche, Elche, Spain, 3Departamento de Medicina Clínica, Emeritus Professor, Universidad Miguel Hernández, Alicante, Spain

    Background/Purpose: In inflammatory disorders, highest incidence of cardiovascular (CV) events paradoxically occurs at lower lipid levels [ARD.70:482], especially for high-density lipoprotein cholesterol (HDLc). Current data…
  • Abstract Number: 189 • 2016 ACR/ARHP Annual Meeting

    Nutraceutical Therapy with Polyphenol-Rich Pomegranate Fruit Extract (POMx) Inhibits Systemic NFκB-Mediated Inflammation in a Murine Model of Endotoxemia

    Nicholas A. Young1, Misha Mobeen2, Tariq M Haqqi3 and Wael N. Jarjour4, 1Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3Anatomy & Neurobiology, Northeast Ohio Medical University, Rootstown, OH, 4Department of Rheumatology/Medicine, Ohio State University, Columbus, OH

    Background/Purpose:  The pomegranate fruit is cultivated worldwide for dietary consumption, but has been used therapeutically in Eastern medicine from times dating back to ancient Egypt…
  • Abstract Number: 1442 • 2016 ACR/ARHP Annual Meeting

    Suppression of Acute Arthritis By N-Methyl-3,4-Dichloropropionaniline (N-MeDCPA), a Reversible Orai Calcium Channel Inhibitor

    John Barnett1, Lisa Robinson2, Jonathan Soboloff3, Rosana Schafer4, Ida Holaskova5, Meenal Elliott1, Michelle Witt2, Raphael Hirsch6 and Harry Blair7, 1Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV, 2Pathology, West Virginia University, Morgantown, WV, 3Dept of Medical Genetics and Molecular Biochemistry, Temple University, Philadelphia, PA, 4Dept Micro, Immun & Cell Biol, West Virginia University, Morgantown, WV, 5West Virginia University, Morgantown, WV, 6Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, 7pathology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:  Bone maintenance is a balance between the removal of old bone by osteoclasts (OCL) and the production of new bone by osteoblasts. In the…
  • Abstract Number: 2343 • 2016 ACR/ARHP Annual Meeting

    A Phase 2, Multi-Center, Randomized, Double-Blind, Active-Controlled, Parallel Group Study to Evaluate the Safety and Dose Effectiveness of Intradermal Injections of Purified Apis Mellifera Toxin to Improve Pain and Physical Function in Patients with Osteoarthritis of the Knee

    Douglas R. Schumacher1, Anna Jakubowska2 and Christopher M.H. Kim3, 1Radiant Research, Columbus, OH, 2Apimeds, Inc., Jungwongu, Seongnam, Gyeonggido, Korea, The Republic of, 3CHA University, Bundanggu, Seongnam, Gyeongghido, Korea, The Republic of

    Background/Purpose: This Phase 2a/b trial evaluated the safety and dose effectiveness of honeybee toxin (purified Apis melliferatoxin) injections to improve pain and physical function in…
  • Abstract Number: 271 • 2016 ACR/ARHP Annual Meeting

    Impaired Satellite Cell Activation and Myofiber Transition during Skeletal Muscle Regeneration in Patients with Polymyositis and Dermatomyositis

    Beatriz Hanaoka1, Prabhakara R. Nagareddy2, Marilyn Campbell3, Leslie J. Crofford4, Charlotte A. Peterson5, Lisa G. Rider6 and Frederick W. Miller7, 1Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2Nutritional Sciences, University of Alabama at Birmingham, Birmingham, AL, 3University of Kentucky, Lexington, KY, 4Medicine, Vanderbilt University Medical Center, Nasville, TN, 5College of Health Sciences, University of Kentucky, Lexington, KY, 6Rheumatology, George Washington University, Washington, DC, 7Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD

    Background/Purpose: Satellite cells are myogenic stem cells that are essential for myofiber repair, growth and homeostasis in postnatal life. A decline in satellite cell performance…
  • Abstract Number: 1471 • 2016 ACR/ARHP Annual Meeting

    Myocardial 18f-Fluorodeoxyglucose (18F-FDG) Uptake in RA Patients without Clinical Cardiovascular Disease Is Higher Than in Controls and Decreases with Treatment

    Isabelle Amigues1, Jon T. Giles2, Afshin Zartoshti3, Rachelle Morgenstern4, Raul Flores5, Sabahat Bokhari6 and Joan Bathon7, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Rheumatology, Columbia University Medical Center, NY, NY, 3Rheumatology, Columbia University, College of Physicians & Surgeons, New York city, NY, 4Cardiology, columbia university college of physicians and surgeons, New York city, NY, 5Medicine, Columbia University, New York Presbyterian, New York city, NY, 6Cardiology, Columbia University College of Physicians & Surgeons, NY, NY, 7Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose:   Symptomatic heart failure (HF) and HF-associated mortality rates are higher in RA compared with the non-RA population, even after controlling for coronary artery…
  • Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting

    Obesity-Related Systemic Inflammation and Knee Synovitis

    Devyani Misra1, Tuhina Neogi2, Michael C. Nevitt3, James Torner4, Cora E. Lewis5 and David T. Felson6, 1Medicine, Section of, BUSM, Boston, MA, 2Clinical Epidemiology, BUSM, Boston, MA, 3Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 4University of Iowa, UIowa, Iowa City, IA, 5University of Alabama Birmingham, Birmingham, AL, 6Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
  • « Previous Page
  • 1
  • …
  • 42
  • 43
  • 44
  • 45
  • 46
  • …
  • 58
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology