Abstracts tagged "inflammation and mitochondria"

Abstract Number: 1988 • 2018 ACR/ARHP Annual Meeting
Effect of Different Fucoidans on Pathological Pathways Activated in Osteoarthritic Chondrocytes and Synoviocytes
María José Lamas Vázquez¹, Rosa Meijide-Failde¹, Francisco J Blanco², Herminia Domínguez³ and Carlos Vaamonde-Garcia⁴, ¹Department of Physiotherapy, Medicine and Biological Sciences, Tissue Engineering and Regenerative Medicine group (University of A Coruña), A Coruña, Spain, ²Rheumatology Division, CIBER-BBN/ISCIII, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, ³Facultad de Ciencias. Campus de Ourense (University of Vigo), Ourense, Spain, ⁴Department of Physiotherapy, Medicine and Biological sciences, Tissue Engineering and Regenerative Medicine group (University of A Coruña), A Coruña, Spain
Background/Purpose: Osteoarthritis (OA) is a disease managed rather than cured, with a focus on alleviating its pain. Recent studies show that fucoidans, one of the…
Abstract Number: 1827 • 2013 ACR/ARHP Annual Meeting
The Intraarticular Injection Of An Inhibitor Of Complex V Of Mitochondrial Respiratory Chain Induces a Pathological Response In Rat Knee Joints
Carlos Vaamonde-García¹, Jesus Loureiro¹, Eduardo López-Peláez², Alberto Centeno-Cortés², Romina R. Riveiro-Naveira¹, M. Noa Valcárcel-Ares¹, Francisco J. Blanco³ and Maria J. López-Armada¹, ¹Aging and Inflammation Research Lab, INIBIC-CHU A Coruña, A Coruña, Spain, ²Experimental Surgery Unit, CHU A Coruña, A Coruña, Spain, ³Osteoarticular and Aging Res. Lab. CIBER-BBN. INIBIC- University of A Coruña, A Coruña, Spain
Background/Purpose: A decline of mitochondrial function has been described in OA chondrocytes and RA synoviocytes. Recent ex vivo findings support a connection between mitochondrial dysfunction…

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