Abstracts tagged "Infection"

Abstract Number: 0638 • ACR Convergence 2021
Improving Safety in Rheumatology Patients by Closing Pre-screening Laboratory Care Gaps
P. Daniel Nicholas¹, Jonida Cote², Dante Grassi¹, Swana Thomas³, Joseph Chronowski¹, David Pugliese⁴ and Eric Newman¹, ¹Geisinger Medical Center, Danville, PA, ²Geisinger Medical Center, Orefield, PA, ³Geisinger Medical Center, Wilkes-Barre, PA, ⁴Geisinger Medical Center, Wilkes Barre, PA
Background/Purpose: The Centers for Disease Control and Prevention and expert rheumatologists recommend screening for HBV and HCV prior to DMARD initiation and the ACR recommends…
Abstract Number: 1528 • ACR Convergence 2021
Clinical Consequences of Hepatitis B Core Antibody Positivity After IVIG Administration
William West¹, Therese Posas-Mendoza², Jerald Zakem³, William Davis¹ and Robert Quinet⁴, ¹Ochsner Medical Center, New Orleans, LA, ²Ochsner Clinic Foundation, New Orleans, LA, ³Ochsner Health Systems, Metairie, LA, ⁴Ochsner Health, River Ridge, LA
Background/Purpose: Intravenous immunoglobulin (IVIG) is a blood product created by pooling of donor plasma that is used for a wide range of indications. IVIG is…
Abstract Number: 0639 • ACR Convergence 2021
Improving Pre-biologic Infection Screening Using a Best Practice Alert in Electronic Health Records
Hailey Baker¹, Rebecca Fine¹, Betty Hsiao², Vaidehi Chowdhary³, Lisa Suter⁴ and Abhijeet Danve⁵, ¹Yale University, New Haven, CT, ²Yale-New Haven Medical Center, New Haven, CT, ³Yale University, East Haven, CT, ⁴Yale School of Medicine, New Haven, CT, ⁵Yale University, Rocky Hill, CT
Background/Purpose: Biologics and small molecules (bDMARDs) are important immunomodulatory medications for management of patients with rheumatic diseases. Use of a bDMARD in patients with infection…
Abstract Number: 1534 • ACR Convergence 2021
Severity Factors of Covid-19 Infection in Rheumatic Immune-mediated Inflammatory Diseases: Study in a Single University Hospital
David Martinez-Lopez¹, Diana Prieto-Peña¹, Lara Sánchez-Bilbao¹, Carmen Álvarez-Reguera¹, Alba Herrero-Morant¹, Fabricio Benavides-Villanueva¹, Cristina Corrales-Selaya¹, Martin Trigueros-Vazquez¹, Miguel Ángel gonzalez-Gay², Ricardo Blanco³ and Reinhard Wallmann⁴, ¹Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, ³Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ⁴Cantabria Health Service, Santander, Spain
Background/Purpose: Severity factors for COVID-19 have been widely studied in the general population. However, the severity factors and characteristics of COVID-19 in patients with rheumatic…
Abstract Number: L04 • ACR Convergence 2020
Influenza Adverse Events in Patients with Rheumatoid Arthritis in the Tofacitinib Clinical Program
Kevin L Winthrop¹, Arne Yndestad², Dan Henrohn³, Hyejin Jo⁴, Sara Marsal⁵, Maria Galindo⁶, Annette Diehl⁷, Andrea B Shapiro⁸ and Stanley B Cohen⁹, ¹Oregon Health & Science University, Portland, OR, ²Pfizer Inc, Oslo, Norway, ³Pfizer Inc, Sollentuna, Sweden, ⁴Syneos Health, Raleigh, NC, ⁵Vall d’Hebron Hospital, Barcelona, Spain, ⁶Rheumatology Unit, Hospital Universitario 12 de Octubre, Madrid, Spain, ⁷Pfizer Inc, Collegeville, PA, ⁸Pfizer Inc, Peapack, NJ, ⁹Metroplex Clinical Research Center, Dallas, TX
Background/Purpose: Patients (pts) with RA have increased susceptibility to seasonal influenza and its complications.1 The COVID-19 pandemic highlights the need to understand acute respiratory RNA…
Abstract Number: 0057 • ACR Convergence 2020
Increased Susceptibility to Measles in Patients from Central America and Mexico in a U.S. Rheumatology Clinic
Alice Fike¹, Abhimanyu Amarnani², Yanira Ruiz-Perdomo³, Sarfaraz Hasni³, Michael Ward³ and James Katz⁴, ¹NIAMS, Bethesda, MD, ²SUNY Downstate Health Sciences University, Brooklyn, NY, ³National Institutes of Health, Bethesda, MD, ⁴NIH NIAMS, Bethesda, MD
Background/Purpose: Infections in patients with rheumatic disease are a leading cause of morbidity and mortality. Preventive measures such as immunizations can reduce the burden of…
Abstract Number: 0604 • ACR Convergence 2020
Increasing the Rate of Pneumococcal Vaccination in an Academic Rheumatology Outpatient Clinic
Maria Bacalao¹, Swathi Reddy² and Nilofar Syed³, ¹UT Southwestern, Dallas, TX, ²Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX, ³UT Southwestern Medical Center, RICHARDSON, TX
Background/Purpose: Many patients with rheumatic diseases are at increased risk of infection, including invasive pneumococcal infection, due to both disease-related abnormalities of the immune system as…
Abstract Number: 1026 • ACR Convergence 2020
The Incidence, Mortality, and Economic Burden of Potentially Preventable Infections in Systemic Lupus Erythematosus Patients
Estefania Gauto-Mariotti¹, Soumyasri Kambhatla² and Augustine Manadan³, ¹John H. Stroger Jr. Hospital of Cook County, Chicago, IL, ²John H Stroger Hospital of Cook County, Riverside, IL, ³Rush University Medical Center, Chicago, IL
Background/Purpose: Streptococcus pneumoniae, Herpes zoster, and influenza infections are common and potentially preventable causes of morbidity and mortality. Vaccinations have been shown to reduce infection…
Abstract Number: 1997 • ACR Convergence 2020
Immunogenicity of Adjuvanted Herpes Zoster Subunit Vaccine in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors and Controls: Preliminary Results
Hanna Källmark¹, Birgitta Gullstrand², Johanna Nagel³, Jon Einarsson¹, Göran Jönsson⁴, Fredrik Kahn⁵, Robin Kahn⁶, Anders Bangtsson², Tomas Bergström⁷ and Meliha Kapetanovic¹, ¹Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden and Skåne University Hospital Sweden., Lund, Sweden, ²Department of Rheumatology, Clinical Sciences, Lund University Sweden, Lund, Sweden, ³Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Rheumatology, Lund, Sweden, Lund, Sweden, ⁴Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden, Lund, Sweden, ⁵Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden, Lund, Sweden, ⁶Department of Clinical Sciences Lund, Section of Pediatrics, Lund University, Lund, Sweden; Wallenberg Centre of Molecular Medicine, Lund University, Lund, Sweden, ⁷Department of Infectious Diseases, Section for Clinical Virology, Institute of Biomedicine, University of Gothenburg, Sweden, Gothenburg, Sweden
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of contracting herpes zoster (HZ) and treatment with JAnus Kinase inhibitors (JAKi) further adds on…
Abstract Number: 0069 • ACR Convergence 2020
Identification of CD13 as a Potential Cause for SARS-CoV-2-triggered Hyperinflammation and Thrombosis
Eliza Pei-Suen Tsou¹, Gautam Sule¹, Mikel Gurrea Rubio², M. Asif Amin¹, Yu Zuo¹, Jason Knight¹, Yogendra Kanthi³ and David Fox¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Division of Rheumatology, University of Michigan, Canton, MI, ³Division of Cardiovascular Medicine, Ann Arbor
Background/Purpose: The ectopeptidase CD13, which is highly expressed on stromal and myeloid cells in joints, lung and other tissues, is a known receptor for many…
Abstract Number: 0622 • ACR Convergence 2020
Infection-induced MPO-ANCA Associated Vasculitis: A Systematic Review of Published Case Reports
Konstantinos Parperis¹, Loukas Kakoullis², Eleni Papachristodoulou³ and George Panos³, ¹University of Arizona College of Medicine Phoenix and University of Cyprus Medical School, Phoenix, ²University of Patras School of Health Sciences, Patras, Akhaia, Greece, ³University of Cyprus Medical School, Nicosia, Nicosia, Cyprus
Background/Purpose: Anti-myeloperoxidase (MPO) antineutrophil cytoplasmic antibody (ANCA) has been implicated in the pathogenesis of microscopic polyangiitis (MPA) and an MPO-ANCA associated glomerulonephritis; both conditions are…
Abstract Number: 1099 • ACR Convergence 2020
High Burden of Infections in Indian Patients with Idiopathic Inflammatory Myopathy: Validation of Observations from the MyoCite Dataset
Rudrarpan Chatterjee¹, Pankti Mehta², Vikas Agarwal¹ and Latika Gupta², ¹Sanjay Gandhi Post Graduate Institute of Medical Sciences, lucknow, Lucknow, Uttar Pradesh, India, ²Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Background/Purpose: Infections are a major cause of morbidity and mortality in idiopathic inflammatory myopathy (IIM), more so in India.[1-3] The objective of this study was…
Abstract Number: 0079 • ACR Convergence 2020
Analysis of COVID-19 and Rheumatology Twitter Activity During the Pandemic Months
Mosaab Mohameden¹ and Ali H.Ali², ¹University of Cincinnati College of Medicine, Cincinnati, OH, ²University of California San Francisco Fresno, Fresno, CA
Background/Purpose: Twitter is a popular social media platform that is widely used to publish information and exchange ideas. There are over 300 million active monthly…
Abstract Number: 0627 • ACR Convergence 2020
Complications of COVID-19 Infection in Patients with Rheumatic Disease: A Case Series
Timothy Buckey¹, Mali Jurkowski¹, Kevin Lu², Roberto Caricchio² and Aruni Jayatilleke², ¹Temple University, Philadelphia, PA, ²Section of Rheumatology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA
Background/Purpose: People with rheumatic diseases may be at high risk for poor outcomes related to COVID-19; on the other hand, immunomodulatory medications are used as…
Abstract Number: 1165 • ACR Convergence 2020
Validation of Healthcare Claims Algorithms for Identification of Herpes Zoster Among Children with Autoimmune/Autoinflammatory Disease
Beth Rutstein¹, Sabrina Gmuca², Jeffrey S. Gerber² and Alexis Ogdie³, ¹The Children's Hospital of Philadelphia, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Herpes zoster (HZ) is a known serious infectious complication in children with autoimmune/autoinflammatory disease and potentially exacerbated by immunomodulatory medications. Information on HZ burden…

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