ACR Meeting Abstracts

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Abstracts tagged "Infection"

  • Abstract Number: 0801 • ACR Convergence 2022

    Impact of Diagnosis and Treatment of Tropheryma Whipplei Infection in Patients with Pre-existing Chronic Inflammatory Rheumatic Diseases: Data from the National Tw-IRD Registry

    Damien CAILLET PORTILLLO1, Xavier Puéchal2, Yannick Degboe1, Marie Kostine3, Alexia Michaut4, Andre Ramon5, Daniel Wendling6, Nathalie Costedoat-Chalumeau7, Pascal Richette8, Hubert Marotte9, Justine VIX10, Jean Jacques Dubost11, Sebastien Ottaviani12, Gaël Mouterde13, Anne Grasland14, Aline Frazier-Mironer15, Vincent GERMAIN16, Fabienne COURY17, Anne Tournadre11, Martin Soubrier18, Pauline Brevet19, Laurent Cavalie20, Laurent Arnaud21, Christophe Richez22, Adeline Ruyssen-Witrand23 and Arnaud Constantin24, 1Pierre-Paul Riquet University Hospital, Toulouse & Toulouse III University - Paul Sabatier, Rheumatology, Toulouse, France, 2National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France, 3Pellegrin Hospital, University Hospital of Bordeaux, Rheumatology, Bordeaux, France, 4Hospital center, Loire Vendée Ocean, Rheumatology, La Roche-sur-Yon, France, La Roche-sur-Yon, France, 5University Hospital of DIJON, Rheumatology, Dijon, France, 6CHU, University Teaching Hospital, Besançon, France, 7Inserm DR Paris 5, Paris, France, 8Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, 9INSERM 1059, Saint-Etienne, France, 10University Hospital of poitiers, Rheumatology, Poitiers, France, Poitiers, France, 11University Hospital of Clermont Ferrand, Rheumatology, Clermont-Ferrand, France, 12Hopital Bichat-Claude Bernard, Paris, France, 13Lapeyronie Hospital, Montpellier, France, 14Louis-Mourier Hospital, AP-HP, Colombes, Rheumatology, Colombes, France, 15APHP Hôpital Lariboisire, Paris, France, 16Pau Hospital, Rheumatology, Pau, France, Pau, France, 17Pierre-Bénite Hospital, University Hospital Lyon, Rheumatology, Lyon, France, 18Gabriel-Montpied Hospital, Clermont-Ferrand, France, 19University Hospital of Rouen, Rheumatology, Rouen, France., Le Havre, France, 20Purpan Hospital, Federal Institute of Biology (IFB), University Hospital, Toulouse, Biology, Toulouse, France, 21Hautepierre Hospital, University Hospital of Strasbourg, Rheumatology, Strasbourg, France, 22Université de Bordeaux, Bordeaux, France, 23CHU de Toulouse, Toulouse, France, 24Toulouse University Hospital, Toulouse, France

    Background/Purpose: Tropheryma whipplei (Tw) infection is a rare condition, characterized by inflammatory joint symptoms in more than 75% of the cases, which can lead the…
  • Abstract Number: 1469 • ACR Convergence 2022

    Risk Factors for Herpes Zoster Among Patients with Systemic Lupus Erythematosus

    Caroline Spitznagel, Fedelis Mutiso, Jim Oates and Diane Kamen, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) have a higher prevalence and incidence of herpes zoster (HZ) compared with the general population. Our study was…
  • Abstract Number: 2059 • ACR Convergence 2022

    Association of Hydroxychloroquine with the Incidence of Infectious Disease in Systemic Lupus Erythematosus: Data from the LUNA Registry

    Chiharu Hidekawa1, Ryusuke Yoshimi2, Yusuke Saigusa3, Jun Tamura3, Nobuyuki Yajima4, Naoki Suzuki5, Noriko Kojitani2, Yuji Yoshioka5, Natsuki Sakurai5, Yumiko Sugiyama5, Yosuke Kunishita6, Daiga Kishimoto7, Kana Higashitani5, Yuichiro Sato5, Takaaki Komiya5, Hideto Nagai2, Naoki Hamada5, Ayaka Maeda5, Naomi Tsuchida5, Lisa Hirahara2, Yutaro Soejima5, Kaoru Takase-Minegishi2, Yohei Kirino5, Ken-ei Sada8, Yoshia Miyawaki9, Kunihiro Ichinose10, Shigeru Ohno11, Hiroshi Kajiyama12, Shuzo Sato13, Yasuhiro Shimojima14, Michio Fujiwara15 and Hideaki Nakajima5, 1Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama City, Kanagawa Prefecture, Japan, 2Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan, 4Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan, 5Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan, 6Department of Rheumatology, Yokohama Minami Kyosai Hospital, Yokohama, Kanagawa, Japan, 7Center for Rheumatic Diseases, Yokohama City University Medical Center, Kanazawa-ku Yokohamashi, Japan, 8Department of Clinical Epidemiology, Kochi Medical School, Kochi University, Okayama, Japan, 9Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Yokohama, Japan, 10Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Yokohama, Japan, 11Center for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, Japan, 12Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Yokohama, Japan, 13Department of Rheumatology, Fukushima Medical University School of Medicine, Hikarigaoka, Japan, 14Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan, 15Department of Rheumatology, Yokohama Rosai Hospital, Yokohama, Japan

    Background/Purpose: Infections are significant causes of mortality in patients with systemic lupus erythematosus (SLE), and their prevention is essential. Although some previous reports have shown…
  • Abstract Number: 0372 • ACR Convergence 2022

    Incidence and Risk of Overall Infections in Patients with Ankylosing Spondylitis Receiving Biologic Therapies: A Real-world Prospective Observational Study Using KOBIO Registry

    Kyung Min Ko1 and Su-Jin Moon2, 1International St. Mary's Hospital, Incheon, Republic of Korea, 2Catholic University of Korea, Seoul, Republic of Korea

    Background/Purpose: Infection is a perpetual concern in patients treated with biological therapy. However, long-term real-world data on infectious profile of AS patients are lacking The…
  • Abstract Number: 0804 • ACR Convergence 2022

    Incidence and Risk Factors of Active Tuberculosis in Patients with Rheumatic Diseases Complicated with Tuberculosis Infection: A Multicenter Prospective Cohort Study

    Lifan Zhang1, yuchen liu2, xiaoqing zou3, shi chen2, yanan ma2, huimin ma4, qifei cao4, zhengrong yang4, Fengchun ZHANG5, Yan Zhao5, Xiaofeng Zeng6 and Xiaoqing Liu1, 1Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Clinical Epidemiology Unit, Peking Union Medical College, International Clinical Epidemiology Network; Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, 3Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 4Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 5Peking Union Medical College Hospital, Beijing, China, 6Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China

    Background/Purpose: China remains a high-burden country of both rheumatic disease (RD) and tuberculosis (TB) till today. Patients with RD are considered as a high-risk population…
  • Abstract Number: 1488 • ACR Convergence 2022

    Incremental Healthcare Resource Utilization and Costs of Herpes Zoster in Patients with Psoriatic Arthritis: A Retrospective Cohort Study

    David Singer1, Philippe Thompson-Leduc2, Siyu Ma3, Deepshekhar Gupta4, Wendy Cheng5, Selvam Sendhil6, Manasvi Sundar6, Ella Hagopian5, Mei Sheng Duh7 and Sara Poston1, 1GSK, Philadelphia, PA, 2Analysis Group, Inc., Montréal, QC, Canada, 3GSK/Tufts Medical Center, Boston, MA, 4Analysis Group, Inc., Menlo Park, CA, 5Analysis Group, Inc., Boston, MA, 6Analysis Group, Inc., Los Angeles, CA, 7Analysis Group Inc, Boston, MA

    Background/Purpose: Patients with psoriatic arthritis (PsA) may be at increased risk of herpes zoster (HZ). HZ can involve a painful dermatomal rash and lead to…
  • Abstract Number: 2075 • ACR Convergence 2022

    Risk of Bloodstream Infection in Patients with Systemic Lupus Erythematosus Exposed to Prolonged Moderate to High Dose Glucocorticoids

    MI HYEON KIM1, Eun Bong Lee1, Eun Young Lee2, Jin Kyun Park3 and Jun Won Park1, 1Seoul National University Hospital, Seoul, Republic of Korea, 2Seoul National University College of Medicine, Seoul, Republic of Korea, 3Seoul National University College of Medicine, Jongno-gu, Seoul, South Korea

    Background/Purpose: This study aimed to investigate the incidence and risk factors of bloodstream infection (BSI) in patients with systemic lupus erythematosus (SLE) receiving moderate-to-high dose…
  • Abstract Number: 0389 • ACR Convergence 2022

    Vaccine Effectiveness Among Patients with Psoriatic Disease: A Population-based Study

    Lihi Eder1, Idit Lavi2, Amir Haddad3, Nili Stein4, Ilan feldhamer5, ARNON DOV COHEN5, Walid Saliba2 and Devy Zisman2, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Carmel Medical Center, Haifa, Israel, 3Carmel Medical Centre, Haifa, Israel, 4Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel, 5Clalit Health Services, Tel Aviv, Israel

    Background/Purpose: We assess the effectiveness of COVID-19 vaccination in preventing SARS-CoV2 infection and COVID-19 hospitalizations in patients with psoriatic disease (PsD) and non-psoriatic controls, and…
  • Abstract Number: 0806 • ACR Convergence 2022

    Long-term Effectiveness of Sublingual Polybacterial Vaccines in Patients with Systemic Autoimmune Disease and Active Pharmacological Immunosuppression

    Inés Pérez Sancristóbal1, María Paula Álvarez Hernández2, Silvia Sanchez - Ramon3, Cristina Martinez4, Eduardo de la Fuente3, Concepcion Morado4, Dalifer Freites Nuñez2, Benjamin Fernandez Gutierrez5 and Gloria Candelas4, 1Instituto de Investigación Sanitaria San Carlos, Rheumatology, Madrid, Spain, 2Hospital Clínico San Carlos, Madrid, Spain, 3Department of Clinical Immunology, IML and IdSSC, Hospital Clínico San Carlos, Madrid, Spain, 4Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 5Hospital Clínico San Carlos, Rheumatology Deparment, Madrid, Spain

    Background/Purpose: Infections in patients with systemic autoimmune disease (SAD) are associated with immune dysfunction, disease activity and immunosuppression. Synthetic and biologic disease-modifying drugs (DMARDs) have…
  • Abstract Number: 1525 • ACR Convergence 2022

    Breakthrough Infections in COVID-19 Vaccinated Patients with Systemic Sclerosis: A Survival Analysis from a Multicenter International Patient-Reported Survey

    Sakir Ahmed1, Naveen R2, John Pauling3, Darpan Thakare2, Chris Wincup4, Nicoletta Del Papa5, Gianluca Sambataro6, Fabiola Atzeni7, SIMONE PARISI8, Marcello Govoni9, Elena Bartoloni Bocci10, Gian Domenico Sebastiani11, Enrico Fusaro12, Marco Sebastiani13, Luca Quartuccio14, Franco Franceschini15, Pier Paolo Sainaghi16, Giovanni Orsolini17, Rossella De Angelis18, Maria Giovanna Danielli19, Vincenzo Venerito20, Parikshit Sen21, Minchul Kim22, Abraham Edgar Gracia-Ramos23, Akira Yoshida24, James B. Lilleker25, Vishwesh Agarwal26, Sinan Kardes27, Jessica Day28, Mrudula Joshi29, Marcin Milchert30, Tamer A Gheita31, Babur Salim32, Ioannis Parodis33, Albert Selva O’Callaghan34, Elena Nikiphorou35, Tulika Chatterjee22, Ai Lyn Tan36, Arvind Nune37, Lorenzo Cavagna38, Samuel Shinjo39, Nelly Ziade40, Johannes Knitza41, Hector Chinoy42, Oliver Distler43, Masataka Kuwana44, Rohit Aggarwal45, Latika Gupta46, Vikas Agarwal2 and Ashima Makol47, 1Kalinga Institute of Medical Sciences, Bhubaneswar, India, 2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 3North Bristol NHS Trust, Bristol, United Kingdom, 4University College London, London, United Kingdom, 5Unità operativa complessa (UOC) Day Hospital Reumatologia via Gaetano Pini 9, Centro Specialistico Ortopedico Traumatologico, Gaetano Pini-CTO, Milano, Italy, 6Medico Immunologia e reumatologia presso, Artoreuma S.R.L., Cors S, Mascalucia, 7Rheumatology Unit, University of Messina, Messina, Italy, 8Italian Society for Rheumatology, Turin, Italy, 9S. Anna Hospital and University of Ferrara, Ferrara, Italy, 10Rheumatology Unit. Department of Medicine, Perugia, Perugia, Italy, 11U.O.C. Reumatologia, Ospedale San Camillo-Forlanini,, Roma, 12Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy, 13Azienda Policlinico di Modena, Modena, Italy, 14Clinic of Rheumatology, Department of Medicine (DAME), ASUFC, University of Udine, Udine, Italy, 15Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, 16Interdisciplinary Research Center of Autoimmune Diseases, Novara, Italy, 17Department of Medicine, Rheumatology Unit, University of Verona, Verona, Verona, 18Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy, 19Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle, Marche, Italy, 20Department of Emergency and Organ Transplantations-Rheumatology Unit, University of Bari "Aldo Moro", Bari, Italy, 21Maulana Azad Medical College, New Delhi, India, 22University of Illinois College of Medicine Peoria, Peoria, IL, 23Instituto Mexicano del Seguro Social, Ciudad de México, Mexico, 24Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan, 25The University of Manchester, Manchester, United Kingdom, 26Mahatma Gandhi Missions Medical College, Lucknow, India, 27Istanbul University, Istanbul, Turkey, 28Walter and Eliza Hall Institute, Melbourne, Australia, 29Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 30Pomeranian Medical University in Szczecin, Szczecin, Poland, 31Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, 32Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, 33Karolinska Institutet, Stockholm, Sweden, 34Hospital Universitari Vall d'Hebron, Barcelona, Spain, 35Leiden University Medical Center & King's College London, London, United Kingdom, 36University of Leeds, Leeds, United Kingdom, 37Southport and Ormskirk Hospital NHS Trust, Southport, United Kingdom, 38Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Pavia, Italy, 39Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil, 40Saint-Joseph University, Beirut, Lebanon, 41Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 42The University of Manchester, Sale, United Kingdom, 43Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 44Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 45Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 46Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 47Mayo Clinic, Rochester, MN, Rochester, MN

    Background/Purpose: Patients with systemic autoimmune rheumatic diseases (AIRDs) are considered more susceptible to break through infection (BI) following vaccination due to their immunosuppressed status and…
  • Abstract Number: 2193 • ACR Convergence 2022

    Invasive Fungal Diseases in Patients with Autoimmune Diseases: Prospective Data from a Nationwide French Registry

    Simon Galmiche1, Benjamin Thoreau2, Stéphane Bretagne3, Alexandre Alanio3, André Paugam4, Valérie Bru5, Sophie Cassaing6, Jean-Pierre Gangneux7, Hélène Guégan7, Loïc Favennec8, Alida Minoza9, Florent Morio10, Julie Bonhomme11, Guillaume Desoubeaux12, Odile Eloy13, Lilia Hasseine14, Milène Sasso15, Laurence Millon16, Anne-Pauline Bellanger16, Philippe Poirier17, Maxime Moniot17, Taieb Chouaki18, Antoine Huguenin19, Frédéric Dalle20, Bernard Bouteille21, Muriel Nicolas22, Nicole Desbois-Nogard23, Marie-Elisabeth Bougnoux24, François Danion25, Vincent Poindron26, Antoine Néel27, Karine Boukris-Sitbon28, Fanny Lanternier29 and Benjamin Terrier30, 1Institut Pasteur, Paris, France, 2AP-HP, Université Paris Cité, INSERM U1016, CNR UMR 8104, Paris, France, 3Institut Pasteur, Université Paris Cité, Centre National de Référence Mycoses Invasives et Antifongiques, UMR 2000, AP-HP, Paris, France, 4Parasitologie – Mycologie, Université Paris Cité, Cochin Hospital, AP-HP, Paris, France, 5Institut de parasitologie et de pathologie tropicale, Hôpitaux universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France, 6Parasitologie - Mycologie, Université de Toulouse, CHU de Toulouse, Toulouse, France, 7Université de Rennes, CHU, INSERM, Irset: Institut de Recherche en Santé, Environnement et Travail, UMR_S 1085, Rennes, France, 8French National Cryptosporidiosis Reference Center, Rouen University Hospital, Rouen, France, 9Département des agents infectieux, Service de Mycologie-Parasitologie, CHU de Poitiers, Poitiers, France, 10Parasitologe – Mycologie, CHU de Nantes, Nantes, France, 11Microbiologie, CHU de Caen, Caen, France, 12Parasitologie - Mycologie - Médecine tropicale, CHU de Tours, Tours, France, 13Microbiologie, Hôpital de Versailles, Le Chesnay, France, 14Parasitologie – Mycologie, hôpital de l'Archet, CHU Nice, Nice, France, 15Laboratoire de Parasitologie-Mycologie, CHU Nîmes, Université de Montpellier, CNRS, IRD, MiVEGEC, Nîmes, France, 16Laboratoire de Parasitologie – Mycologie, CHU Besançon, Besançon, France, 17Parasitologie – Mycologie, CHU de Clermont-Ferrand, Clermont-Ferrand, France, 18Mycologie – parasitologie, CHU d’Amiens, Amiens, France, 19Parasitologie – Mycologie, hôpital Maison-Blanche, CHU de Reims, Reims, France, 20Parasitologie – Mycologie, Plateforme de Biologie Hospitalo-Universitaire Gérard Mack, Dijon, France, 21Parasitologie – Mycologie, Centre de Biologie et de Recherche en Santé, CHU Dupuytren, Limoges, France, 22Mycologie – Parasitologie, CHU de Pointe-à-pitre/Abymes, Pointe-à-Pitre, France, 23Parasitologie – Mycologie, CHU de la Martinique, Fort-de-France, France, 24Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Mycologie, Laboratoire de Parasitologie – Mycologie, Service de Microbiologie, Necker-Enfants Malades University Hospital, AP-HP, Paris, France, 25Maladies infectieuses et tropicales, Hôpitaux universitaires de Strasbourg, Strasbourg, France, 26Immunologie clinique et médecine interne, Hôpitaux universitaires de Strasbourg, Strasbourg, France, 27CHU de Nantes, Nantes, France, 28Institut Pasteur, Université Paris Cité, CNRS, Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, UMR 2000, Paris, France, 29Infectious Diseases Unit, Necker-Enfants Malades University Hospital, AP-HP, Institut Pasteur, Université Paris Cité, Centre National de Référence Mycoses Invasives et Antifongiques, CNRS UMR 2000, Paris, France, 30National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France

    Background/Purpose: Patients with autoimmune diseases (AIDs) display a risk of invasive fungal diseases (IFDs), because of the underlying disease or treatments used. Our objective was…
  • Abstract Number: 0398 • ACR Convergence 2022

    Comparison of Spondyloarthritis, Rheumatoid Arthritis and Knee Osteoarthritis Occurring in the Setting of HIV Infection

    Benjamin Naovarat1, John Reveille1, Mark Hwang2, Francis Williams3 and Gloria Salazar4, 1University of Texas McGovern Medical School, Houston, TX, 2McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, 3Specialists for Health/Wellmed, Shavano Park, TX, 4University of Texas Medical School at Houston/McGovern Medical School, Houston, TX

    Background/Purpose: Early in the HIV epidemic, autoimmune diseases such as lupus and rheumatoid arthritis (RA) were uncommonly encountered. With the advent of combined antiretroviral therapy…
  • Abstract Number: 0835 • ACR Convergence 2022

    Temporal Trends in Prosthetic Joint Infection

    Anne Bass1, Yi Zhang,2, Peter Sculco2, huong do2, Kayla Glaser2, alberto Carli2, Mark Figgie2 and Susan Goodman2, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY

    Background/Purpose: Prosthetic joint infection (PJI) is a dreaded complication of total knee replacement (TKR) that usually requires removal of the prosthesis, treatment with antibiotics and…
  • Abstract Number: 1592 • ACR Convergence 2022

    Serious Infections in SLE- Incidence, Associated Factors, Impact and Trends over Two Decades

    Rudrarpan Chatterjee, Sarit Sekhar Pattanaik, Durga P Misra, Vikas Agarwal, Able Lawrence and Amita Aggarwal, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

    Background/Purpose: Infections are a major cause of morbidity and mortality in systemic lupus erythematosus (SLE). We assessed the incidence and risk factors for major infections…
  • Abstract Number: 2218 • ACR Convergence 2022

    Frailty Is Associated with Serious Infections in Biologic and Targeted-synthetic DMARD Treated Patients with Rheumatoid Arthritis

    Namrata Singh1, Laura Gold2, Katherine Wysham3, James Andrews2, Pankti Reid4, Una Makris5, Bryant England6, Jiha Lee7, Michael George8, Joshua Baker9, Jeffrey Jarvik2, Patrick Heagerty2 and Siddharth Singh10, 1University of Washington, Bellevue, WA, 2University of Washington, Seattle, WA, 3VA Puget Sound/University of Washington, Seattle, WA, 4University of Chicago Medical Center, Chicago, IL, 5UT Southwestern Medical Center and Dallas VA, Dallas, TX, 6University of Nebraska Medical Center, Omaha, NE, 7University of Michigan, Ann Arbor, MI, 8University of Pennsylvania, Philadelphia, PA, 9University of Pennsylvania and Corporal Michael J. Crescenz VA Medical Center, Philadelphia, 10University of California San Diego, San Diego

    Background/Purpose: Recently, it has been recognized that frailty and pre-frailty are common in patients with rheumatoid arthritis (RA) [1]. Whether frailty status portends an increased…
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