Abstracts tagged "Imaging"

Abstract Number: 0962 • ACR Convergence 2025
Spatial Proteomics Analysis of the organization of tertiary lymphoid structures in Systemic Sclerosis Skin
Dennis Bleck¹, Karen Drechsel², Tim Filla³, Yi-Nan Li⁴, Andrea-Hermina Györfi⁵, Alexandru-Emil Matei⁶ and Jörg Distler⁷, ¹University Hospital Düsseldorf, Department of Rheumatology, Hiller Research Center, Düsseldorf, Nordrhein-Westfalen, Germany, ²University Hospital Düsseldorf, Department of Rheumatology, Hiller Research center, Düsseldorf, Nordrhein-Westfalen, Germany, ³Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University., Düsseldorf, Germany, ⁴University Hospital of Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany, ⁵Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University., Düsseldorf, Germany, ⁶Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany, Düsseldorf, Germany, ⁷University Hospital Duesseldorf and HHU, Duesseldorf, Germany
Background/Purpose: Systemic Sclerosis (SSc) is a rare autoimmune connective tissue disease and presents a significant medical challenge. It is characterized by fibrotic tissue remodeling, along…
Abstract Number: 0419 • ACR Convergence 2025
Ultrasound-Guided Synovial Biopsy in Children and Adolescents with Juvenile Arthritis: Initial Results
Patricia Vega-Fernandez¹, Kelly Rogers², Megan Quinlan-Waters³, Sheila Angeles-Han², Alexei Grom¹, Daniel Lovell¹, Jennifer Huggins⁴, Ekemini Ogbu¹, Amy Cassedy⁵, Sara Szabo¹, Tracy Ting¹, Grant Schulert¹, McKenzie Vater⁶, Hermine Brunner¹, Jackeline Rodriguez-Smith¹ and Katelyn Banschbach⁷, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children's Hospital, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, CCHMC, ⁴Cincinnati Children's Medical Center, Cincinnati, OH, ⁵Cincinnati Children's hospital medical center, cincinnati, OH, ⁶Cincinnati Children's Hospital Medical Center, Fort Thomas, KY, ⁷cincinnati Children's hospital, Villa Hills, KY
Background/Purpose: Ultrasound-guided synovial biopsy (USGSB) has been recently implemented for clinical and research purposes in adults with inflammatory arthritis. The current use of USGSB in…
Abstract Number: 2319 • ACR Convergence 2025
Reducing selection bias while maintaining precision through an integrated analysis: 2-year longitudinal analysis of imaging outcomes in the SPondyloArthritis Caught Early cohort
Liese de Bruin¹, Floris A. van Gaalen¹, Manouk de Hooge², Miranda van Lunteren¹, Mary Lucy Marques³, Monique Reijnierse⁴, Roberta Ramonda⁵, Inger Jorid Berg⁶, Carl Turesson⁷, Robert Landewé⁸, Désirée Van Der Heijde¹ and Sofia Ramiro⁹, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, ⁴Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Padua, Italy, ⁶⁶Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Nepal, ⁷Lund University, Malmö, Sweden, ⁸Department of Rheumatology, Amsterdam University Medical Center, Amsterdam, Netherlands; and Zuyderland Medical Center, Heerlen, Netherlands, ⁹Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: Imaging outcomes in ongoing cohort studies are typically evaluated across multiple reading rounds by several readers. Often, only scores from the most recent reading…
Abstract Number: 1962 • ACR Convergence 2025
Imaging findings in patients with enteropathic spondyloarthritis
Marika Bodnárová¹, Lucia Ondrejčáková², Tomáš Grega³, Ladislav Šenolt⁴, Karel Pavelka⁵ and Kristýna Bubová¹, ¹Institute of Rheumatology, Prague, Czech Republic, ²Institute of Rheumatology, Prague, Hlavni mesto Praha, Czech Republic, ³Military University Hospital Prague, Prague, ⁴Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ⁵Institute of Rheumatology and Department of Rheumatology, ¹st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Enteropathic spondyloarthritis (eSpA) is a subtype of SpA associated with inflammatory bowel disease (IBD). Sacroiliac joints (SIJs) involvement is common in eSpA but often…
Abstract Number: 1937 • ACR Convergence 2025
Does Combining Standard MRI-Based Scores with Radiographic Trabecular Bone Texture Biomarkers Improve Predictive Performance for Radiographic Knee Osteoarthritis Progression?
Ahmad Almhdie-Imjabbar¹, Saida Daroussi², Daniela Herrera³, Hechmi Toumi² and Eric Lespessailles⁴, ¹University Hospital Center of Orleans, Orleans, France, ²PRIMMO- University Hospital Center of Orleans, Orleans, France, ³PRIMMO- University Hospital Center of Orleans, Olreans, France, ⁴CHU Orléans, Orléans, France
Background/Purpose: Knee osteoarthritis (KOA) is a major cause of disability worldwide, particularly impacting the elderly and obese population. Radiographic trabecular bone texture (TBT) is demonstrated…
Abstract Number: 1483 • ACR Convergence 2025
Evidence of Early Cardiovascular Dysfunction in Young Systemic Lupus Erythematosus Patients Compared to Older Healthy Controls
Fernanda M. Garcia-Garcia¹, Oscar Azael Garza-Flores², Esteban C. Garza-Gonzalez³, Rebeca L. Polina-Lugo⁴, Leslie Y. Lopez-Cantú¹, Dionicio A. Galarza-Delgado¹, Iris J. Colunga-Pedraza¹, Jesus Alberto Cardenas-de la Garza⁵, Jose R Azpiri-Lopez⁶ and Victor M Fraga-Enriquez⁷, ¹Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ²Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Guadalupe, Mexico, ³Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo Leon, Mexico, ⁴Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, ⁵Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, ⁶Cardiology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁷Cardiology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by systemic inflammation and accelerated atherosclerosis, leading to increased cardiovascular (CV) risk. While CV…
Abstract Number: 0956 • ACR Convergence 2025
Mapping Metabolic Changes in Skin Fibrosis in Systemic Sclerosis by Spatial Proteomics
Veda Devakumar¹, Yi-Nan Li², Tim Filla³, Aleix Rius Rigau⁴, Andrea-Hermina Györfi⁵, Bilgesu Safak Tümerdem⁶, Ranjana Neelagar⁷, Minrui Liang⁸, Christina Bergmann⁹, Georg Schett¹⁰, Jörg Distler¹¹ and Alexandru-Emil Matei¹², ¹Heinrich Heine University, University Clinic Düsseldorf, Düsseödorf, ²University Hospital of Düsseldorf, Düsseldorf, Germany, ³Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University., Düsseldorf, Germany, ⁴Department of Internal Medicine ³, Rheumatology and Clinical Immunology, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen. Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ⁵Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University., Düsseldorf, Germany, ⁶Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University, Düsseldorf, Nordrhein-Westfalen, Germany, ⁷Heinrich Heine University Duesseldorf, University Hospital Duesseldorf, Düsseldorf, Nordrhein-Westfalen, Germany, ⁸Huashan Hospital, Fudan University, Shanghai, China (People's Republic), ⁹Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, ¹⁰Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, ¹¹University Hospital Duesseldorf and HHU, Duesseldorf, Germany, ¹²Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany, Düsseldorf, Germany
Background/Purpose: Several tissue resident populations undergo metabolic reprogramming during tissue fibrosis as a phenotypic adaptation to their changing metabolic demands. However, these shifts in metabolic…
Abstract Number: 0418 • ACR Convergence 2025
Evaluation of Disease Activity in the Knee Joint Through Clinical, Radiologic, Synovial Fluid and Histopathologic Measurements of Inflammation in Children with Juvenile Idiopathic Arthritis
Patricia Vega-Fernandez¹, Kelly Rogers², Alyssa Sproles², Sherry Thornton¹, Lexi Auld³, Jackeline Rodriguez-Smith¹, Ekemini Ogbu¹, Kara Murphy Schmidt⁴, McKenzie Vater⁵, Katelyn Banschbach⁶, Grant Schulert¹, Alexei Grom¹, Sheila Angeles-Han², Hermine Brunner¹, Jennifer Huggins⁷, Daniel Lovell¹, Amy Cassedy⁸, Yuriy Baglaenko², Tracy Ting¹ and Sara Szabo¹, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children's Hospital, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, Division of Rheumatology, Cincinnati, OH, ⁴Cincinnati Children’s Hospital Medical Center, Louisville, KY, ⁵Cincinnati Children's Hospital Medical Center, Fort Thomas, KY, ⁶cincinnati Children's hospital, Villa Hills, KY, ⁷Cincinnati Children's Medical Center, Cincinnati, OH, ⁸Cincinnati Children's hospital medical center, cincinnati, OH
Background/Purpose: Clinical, radiologic and biomarker data are measurements used in the assessment of juvenile idiopathic arthritis (JIA) disease activity. The development of ultrasound-guided synovial biopsy…
Abstract Number: 2306 • ACR Convergence 2025
Prevalence and Clinical Significance of the Gastrointestinal Fat Halo Sign in Patients with Psoriatic Arthritis: A Cross-Sectional Study
Amir Haddad¹, Kathrien Mousa¹, Kateryna Milman¹, Najwan Nassrallah¹, Devy Zisman² and Sharbell Hashoul³, ¹Carmel Medical Centre, Haifa, Israel, ²Carmel Medical Center, Haifa, Israel, ³The Faculty of Humanities and Social Sciences. Uno Academic College, Haifa, Israel
Background/Purpose: The existence of a gut-joint axis is widely described in spondyloarthritis, linking intestinal dysbiosis, subclinical gut inflammation, and arthritis. The fat halo sign is…
Abstract Number: 1959 • ACR Convergence 2025
The development and validation of a Diagnostic Ultrasound Enthesitis Score (DUET) for Psoriatic Arthritis
Lihi Eder¹, Ricardo Acayaba de Toledo², Catherine Bakewell³, Philippe Carron⁴, Basant Elnady⁵, Amir Haddad⁶, Arthur Kavanaugh⁷, Fahmeen J. Afgani⁸, Arnon Katz⁹, Minna Kohler¹⁰, josefina marin¹¹, Nam Nguyen¹², Adrien NZEUSSEU TOUKAP¹³, Ari Polachek¹⁴, Ernesto Rodriguez¹⁵, Marcos Rosemffet¹⁶, Abha Singh¹⁷, Maria S. Stoenoiu¹⁸, Agnes Szentpetery¹⁹, Iliara Tinazzi²⁰, Janeth Yinh²¹, Mu Yang²², Richard Cook²², Gurjit Kaeley²³ and Sibel Aydin²⁴, ¹University of Toronto, Toronto, ON, Canada, ²Centro Integrado de Pesquisas (CIP) do Hospital de Base de São José do Rio Preto, São José do Rio Preto, Brazil, ³Intermountain Healthcare Medical Group, Salt Lake City, ⁴Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, ⁵Research Centre at Al Hada Armed Forces Hospital, Cairo, Egypt, ⁶Carmel Medical Center, Haifa, Israel, ⁷University of California, San Diego, School of Medicine, San Diego, CA, ⁸Women's College Hospital, Toronto, Canada, ⁹GRAPPA, Seattle, ¹⁰Massachusetts General Hospital, Harvard Medical School, Boston, MA, ¹¹Hospital Universitario Rey Juan Carlos, Madrid, Spain, ¹²University of Toronto, Toronto, Canada, ¹³Cliniques Universitaires Saint-Luc, St.-Lambrechts-Woluwe, Belgium, ¹⁴Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel, ¹⁵Florida Medical Clinic, Tampa, ¹⁶Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ¹⁷Altman Clinical and Translational Research Institute, University of California San Diego, San Diego, CA, ¹⁸Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹⁹Uppsala University Hospital, Djursholm, Sweden, ²⁰Ospedale Sacro Cuore-Don Calabria, Verona, Italy, ²¹Massachusetts General Hospital, Boston, MA, ²²University of Waterloo, Waterloo, Canada, ²³UF COM-J, Ponte Vedra Beach, FL, ²⁴Department of Medicine, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, ON, Canada
Background/Purpose: Enthesitis is a key lesion in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aimed to develop and validate a novel sonographic…
Abstract Number: 1936 • ACR Convergence 2025
A Fully Automated Method for Measuring Minimum Tibiofemoral Joint Space Width in Knee Osteoarthritis Assessment: Data from the FNIH cohort
Ahmad Almhdie-Imjabbar¹, Yousra TOUZANI², Hechmi Toumi² and Eric Lespessailles³, ¹University Hospital Center of Orleans, Orleans, France, ²PRIMMO- University Hospital Center of Orleans, Orleans, France, ³CHU Orléans, Orléans, France
Background/Purpose: Osteoarthritis is one of the most prevalent chronic diseases worldwide, with knee osteoarthritis (KOA) being a particularly painful and debilitating form. The minimum tibiofemoral…
Abstract Number: 1406 • ACR Convergence 2025
A Combined Score of Facet Joint Ankylosis and Syndesmophyte Development Correlates Well with Spinal Mobility in Axial Spondyloarthritis
Ana Bento da Silva¹, Floris A. van Gaalen¹, Robert Landewé², Manouk de Hooge³, Mary Lucy Marques⁴, Miranda van Lunteren¹, Liese de Bruin¹, Gizem Ayan⁵, Xenofon Baraliakos⁶, Monique Reijnierse⁷, Jürgen Braun⁸, Désirée Van Der Heijde¹ and Sofia Ramiro⁹, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Amsterdam University Medical Center, Amsterdam, Netherlands; and Zuyderland Medical Center, Heerlen, Netherlands, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, ⁵Ankara Research and Training Hospital, Ankara, Turkey, ⁶Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁷Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁸Ruhr-University, Bochum, Germany; and Rheumatologische Versorgungszentrum (RVZ) Steglitz, Berlin, Germany, ⁹Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: In axial SpA (axSpA), the computed tomography (CT) syndesmophyte score (CTSS) has shown to capture more spinal structural damage progression and to better correlate…
Abstract Number: 0928 • ACR Convergence 2025
Radiolabelled anti-citrullinated histone antibody CIT-013 as a tool to visualize NET rich inflamed joints in a collagen induced arthritic mouse model
Annemarie Kip¹, Daphne Dorst², Birgitte Walgreen², Monique Helsen², Eric meldrum¹, Renato Chirivi¹ and Marije Koenders², ¹Citryll BV, Oss, Netherlands, ²RadboudUMC, Nijmegen, Netherlands
Background/Purpose: Neutrophil Extracellular Traps (NETs) contribute to the pathophysiology of multiple immune-mediated inflammatory diseases including Rheumatoid Arthritis (RA), and may be promising therapeutic targets. The…
Abstract Number: 0346 • ACR Convergence 2025
Fibroblast Growth Factor-23 and Bone Status in Patients with Chronic Kidney Disease Compared to a Healthy Control Group and Its Relationship with Cardiovascular Risk
José Rodríguez gago¹, Carolina Tornero², Lina León³, María Luisa González-Casaus³, Luisa Fernanda Giraldo³, Gloria del Peso³, Diego Garrido³, Teresa López³, Mónica Coronado³, María Auxiliadora Bajo⁴, Sara García³, María Gema Serrano³, Marta Ossorio³, Alejandro Balsa³ and Pilar Aguado³, ¹Hospital Universitario La Paz, MADRID, ²Hospital La Paz, Madrid, Spain, ³Hospital Universitario La Paz, Madrid, Spain, ⁴Hospital Universitario de la Princesa - ISS Princesa, Madrid, Spain
Background/Purpose: Chronic kidney disease (CKD) is linked to increased vascular comorbidity and fracture risk. This study aims to assess bone status in CKD patients versus…
Abstract Number: L04 • ACR Convergence 2024
Performance of an Artificial Intelligence Model Compared to Multiple Human Experts in Scoring Synovitis Severity and Osteophyte Severity on Joint Ultrasound Images
Anders Weber¹, Mads Ammitzbøll Danielsen², Bill Aplin Frederiksen³, Hilde Berner Hammer⁴, Benjamin Schultz Overgaard³, Lene Terslev², Thiusius Rajeeth Savarimuthu⁵ and Soren Andreas Just³, ¹ROPCA, Odense, Denmark, ²Center for Rheumatology and Spine Disease, Rigshospitalet, Glostrup, Denmark, ³Section of Rheumatology, Department of Medicine, Svendborg Sygehus OUH, Svendborg, Denmark, ⁴Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway, ⁵Mærsk Mc-Kinney Møller Institute, University of Southern Denmark, Odense, Denmark
Background/Purpose: To evaluate the agreement of an artificial intelligence (AI) model designed to assess greyscale and Doppler synovitis severity and osteophyte severity in hand joints…

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